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UniProtKB - Q64511 (TOP2B_MOUSE)

Protein

DNA topoisomerase 2-beta

Gene

Top2b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks.By similarity

Miscellaneous

Eukaryotic topoisomerase I and II can relax both negative and positive supercoils, whereas prokaryotic enzymes relax only negative supercoils.

Catalytic activityi

ATP-dependent breakage, passage and rejoining of double-stranded DNA.PROSITE-ProRule annotationBy similarity

Cofactori

Mg2+PROSITE-ProRule annotationBy similarity, Mn2+PROSITE-ProRule annotationBy similarity, Ca2+PROSITE-ProRule annotationBy similarityNote: Binds two Mg2+ per subunit. The magnesium ions form salt bridges with both the protein and the DNA. Can also accept other divalent metal cations, such as Mn2+ or Ca2+.PROSITE-ProRule annotationBy similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei100ATPBy similarity1
Binding sitei129ATPBy similarity1
Metal bindingi470Magnesium 1; catalyticPROSITE-ProRule annotation1
Metal bindingi550Magnesium 1; catalyticPROSITE-ProRule annotation1
Metal bindingi550Magnesium 2PROSITE-ProRule annotation1
Metal bindingi552Magnesium 2PROSITE-ProRule annotation1
Sitei813Transition state stabilizerBy similarity1
Active sitei814O-(5'-phospho-DNA)-tyrosine intermediateBy similarity1
Sitei865Important for DNA bending; intercalates between base pairs of target DNABy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi157 – 159ATPBy similarity3
Nucleotide bindingi170 – 177ATPBy similarity8
Nucleotide bindingi385 – 387ATPBy similarity3

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

GO - Biological processi

View the complete GO annotation on QuickGO ...

Keywordsi

Molecular functionDNA-binding, Isomerase, Topoisomerase
LigandATP-binding, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-4615885 SUMOylation of DNA replication proteins

Names & Taxonomyi

Protein namesi
Recommended name:
DNA topoisomerase 2-beta (EC:5.99.1.3)
Alternative name(s):
DNA topoisomerase II, beta isozyme
Gene namesi
Name:Top2b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:98791 Top2b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL5564

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00001453702 – 1612DNA topoisomerase 2-betaAdd BLAST1611

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineCombined sources1
Modified residuei3N6-acetyllysineCombined sources1
Cross-linki21Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki22Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki165Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki166Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki216Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki287Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki355Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki361Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki425Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki427Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki434Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki588Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki593Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki623Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki631Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki634Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki664Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki700Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1080Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1202Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1205Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1214Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1215Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1224PhosphoserineBy similarity1
Cross-linki1238Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1250Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1259Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1280PhosphothreonineBy similarity1
Cross-linki1311Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki1315Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1324PhosphoserineCombined sources1
Modified residuei1328PhosphoserineBy similarity1
Modified residuei1330PhosphoserineBy similarity1
Modified residuei1332PhosphoserineBy similarity1
Modified residuei1346PhosphoserineBy similarity1
Modified residuei1358PhosphotyrosineCombined sources1
Modified residuei1363PhosphoserineCombined sources1
Modified residuei1376PhosphoserineCombined sources1
Cross-linki1385Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1387PhosphoserineCombined sources1
Modified residuei1390PhosphothreonineCombined sources1
Modified residuei1400PhosphoserineCombined sources1
Modified residuei1408PhosphotyrosineCombined sources1
Modified residuei1411PhosphoserineBy similarity1
Cross-linki1427Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1428PhosphoserineBy similarity1
Modified residuei1439PhosphoserineBy similarity1
Modified residuei1441PhosphoserineBy similarity1
Cross-linki1443Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1448PhosphoserineBy similarity1
Modified residuei1453PhosphoserineCombined sources1
Modified residuei1460PhosphoserineCombined sources1
Cross-linki1477Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei1509PhosphoserineCombined sources1
Modified residuei1511PhosphoserineCombined sources1
Modified residuei1513PhosphoserineCombined sources1
Modified residuei1537PhosphoserineCombined sources1
Modified residuei1539PhosphoserineCombined sources1
Modified residuei1562PhosphothreonineBy similarity1
Modified residuei1563PhosphoserineBy similarity1
Modified residuei1568PhosphoserineCombined sources1
Modified residuei1596PhosphotyrosineBy similarity1
Modified residuei1600PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ64511
MaxQBiQ64511
PaxDbiQ64511
PeptideAtlasiQ64511
PRIDEiQ64511

PTM databases

iPTMnetiQ64511
PhosphoSitePlusiQ64511

Expressioni

Gene expression databases

BgeeiENSMUSG00000017485 Expressed in 296 organ(s), highest expression level in brain
CleanExiMM_TOP2B
ExpressionAtlasiQ64511 baseline and differential
GenevisibleiQ64511 MM

Interactioni

Subunit structurei

Homodimer (By similarity). Interacts with KIAA1210 (PubMed:28203736).By similarity1 Publication

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sitei498Interaction with DNAPROSITE-ProRule annotation1
Sitei501Interaction with DNAPROSITE-ProRule annotation1
Sitei670Interaction with DNAPROSITE-ProRule annotation1
Sitei671Interaction with DNAPROSITE-ProRule annotation1
Sitei732Interaction with DNAPROSITE-ProRule annotation1
Sitei766Interaction with DNAPROSITE-ProRule annotation1
Sitei940Interaction with DNAPROSITE-ProRule annotation1

Binary interactionsi

WithEntry#Exp.IntActNotes
AicdaQ9WVE03EBI-2325586,EBI-3835567

GO - Molecular functioni

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridi204277, 9 interactors
IntActiQ64511, 7 interactors
MINTiQ64511
STRINGi10090.ENSMUSP00000017629

Structurei

3D structure databases

ProteinModelPortaliQ64511
SMRiQ64511
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini464 – 581ToprimPROSITE-ProRule annotationAdd BLAST118

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni351 – 353Interaction with DNABy similarity3
Regioni999 – 1008Interaction with DNABy similarity10

Sequence similaritiesi

Belongs to the type II topoisomerase family.Curated

Phylogenomic databases

eggNOGiKOG0355 Eukaryota
COG0187 LUCA
COG0188 LUCA
GeneTreeiENSGT00390000016222
HOGENOMiHOG000216693
HOVERGENiHBG052998
InParanoidiQ64511
KOiK03164
OMAiDCASARY
OrthoDBiEOG091G00U2
PhylomeDBiQ64511
TreeFamiTF105282

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
cd00187 TOP4c, 1 hit
cd03365 TOPRIM_TopoIIA, 1 hit
Gene3Di1.10.268.10, 1 hit
3.30.230.10, 1 hit
3.30.565.10, 1 hit
3.40.50.670, 1 hit
3.90.199.10, 1 hit
InterProiView protein in InterPro
IPR012542 DTHCT
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR001241 Topo_IIA
IPR013760 Topo_IIA-like_dom_sf
IPR002205 Topo_IIA_A/C
IPR013758 Topo_IIA_A/C_ab
IPR013757 Topo_IIA_A_a_sf
IPR013759 Topo_IIA_B_C
IPR013506 Topo_IIA_bsu_dom2
IPR018522 TopoIIA_CS
IPR031660 TOPRIM_C
IPR006171 TOPRIM_domain
IPR034157 TOPRIM_TopoII
PANTHERiPTHR10169 PTHR10169, 1 hit
PfamiView protein in Pfam
PF00204 DNA_gyraseB, 1 hit
PF00521 DNA_topoisoIV, 1 hit
PF08070 DTHCT, 1 hit
PF02518 HATPase_c, 1 hit
PF01751 Toprim, 1 hit
PF16898 TOPRIM_C, 1 hit
SMARTiView protein in SMART
SM00433 TOP2c, 1 hit
SM00434 TOP4c, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit
SSF56719 SSF56719, 1 hit
PROSITEiView protein in PROSITE
PS00177 TOPOISOMERASE_II, 1 hit
PS50880 TOPRIM, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q64511-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAKSSLAGSD GALTWVNNAT KKEELETANK NDSTKKLSVE RVYQKKTQLE 
        60         70         80         90        100
HILLRPDTYI GSVEPLTQLM WVYDEDVGMN CREVTFVPGL YKIFDEILVN 
       110        120        130        140        150
AADNKQRDKN MTCIKVSIDP ESNIISIWNN GKGIPVVEHK VEKVYVPALI 
       160        170        180        190        200
FGQLLTSSNY DDDEKKVTGG RNGYGAKLCN IFSTKFTVET ACKEYKHSFK 
       210        220        230        240        250
QTWMNNMMKT SEAKIKHFDG EDYTCITFQP DLSKFKMEKL DKDIVALMTR 
       260        270        280        290        300
RAYDLAGSCK GVKVMFNGKK LPVNGFRSYV DLYVKDKLDE TGVALKVIHE 
       310        320        330        340        350
LANERWDVCL TLSEKGFQQI SFVNSIATTK GGRHVDYVVD QVVSKLIEVV 
       360        370        380        390        400
KKKNKAGVSV KPFQVKNHIW VFINCLIENP TFDSQTKENM TLQPKSFGSK 
       410        420        430        440        450
CQLSEKFFKA ASNCGIVESI LNWVKFKAQT QLNKKCSSVK YSKIKGIPKL 
       460        470        480        490        500
DDANDAGGKH SLECTLILTE GDSAKSLAVS GLGVIGRDRY GVFPLRGKIL 
       510        520        530        540        550
NVREASHKQI MENAEINNII KIVGLQYKKS YDDAESLKTL RYGKIMIMTD 
       560        570        580        590        600
QDQDGSHIKG LLINFIHHNW PSLLKHGFLE EFITPIVKAS KNKQELSFYS 
       610        620        630        640        650
IPEFDEWKKH IENQKAWKIK YYKGLGTSTA KEAKEYFADM ERHRILFRYA 
       660        670        680        690        700
GPEDDAAITL AFSKKKIDDR KEWLTNFMED RRQRRLHGLP EQFLYGTATK 
       710        720        730        740        750
HLTYNDFINK ELILFSNSDN ERSIPSLVDG FKPGQRKVLF TCFKRNDKRE 
       760        770        780        790        800
VKVAQLAGSV AEMSAYHHGE QALMMTIVNL AQNFVGSNNI NLLQPIGQFG 
       810        820        830        840        850
TRLHGGKDAA SPRYIFTMLS SLARLLFPAV DDNLLKFLYD DNQRVEPEWY 
       860        870        880        890        900
IPIIPMVLIN GAEGIGTGWA CKLPNYDARE IVNNVRRMLE GLDPHPMLPN 
       910        920        930        940        950
YKNFKGTIQE LGQNQYAVSG EIFVVDRNTV EITELPVRTW TQVYKEQVLE 
       960        970        980        990       1000
PMLNGTDKTP ALISDYKEYH TDTTVKFVVK MTEEKLAQAE AAGLHKVFKL 
      1010       1020       1030       1040       1050
QTTLTCNSMV LFDHMGCLKK YETVQDILKE FFDLRLSYYG LRKEWLVGML 
      1060       1070       1080       1090       1100
GAESTKLNNQ ARFILEKIQG KITIENRSKK DLIQMLVQRG YESDPVKAWK 
      1110       1120       1130       1140       1150
EAQEKAAEEE DSQNQHDDSS SDSGTPSGPD FNYILNMSLW SLTKEKVEEL 
      1160       1170       1180       1190       1200
IKQRDTKGRE VNDLKRKSPS DLWKEDLAAF VEELDKVEAQ EREDILAGMS 
      1210       1220       1230       1240       1250
GKAIKGKVGK PKVKKLQLEE TMPSPYGRRI VPEITAMKAD ASRKLLKKKK 
      1260       1270       1280       1290       1300
GDPDTTVVKV EFDEEFSGTP AEGTGEETLT PSAPVNKGPK PKREKKEPGT 
      1310       1320       1330       1340       1350
RVRKTPTSTG KTNAKKVKKR NPWSDDESKS ESDLEEAEPV VIPRDSLLRR 
      1360       1370       1380       1390       1400
AAAERPKYTF DFSEEEDDDA AAADDSNDLE ELKVKASPIT NDGEDEFVPS 
      1410       1420       1430       1440       1450
DGLDKDEYAF SSGKSKATPE KSSNDKKSQD FGNLFSFPSY SQKSEDDSAK 
      1460       1470       1480       1490       1500
FDSNEEDTAS VFAPSFGLKQ TDKLPSKTVA AKKGKPPSDT APKAKRAPKQ 
      1510       1520       1530       1540       1550
KKIVETINSD SDSEFGIPKK TTTPKGKGRG AKKRKASGSE NEGDYNPGRK 
      1560       1570       1580       1590       1600
PSKTASKKPK KTSFDQDSDV DIFPSDFTSE PPALPRTGRA RKEVKYFAES 
      1610 
DEEEDVDFAM FN
Length:1,612
Mass (Da):181,909
Last modified:September 27, 2005 - v2
Checksum:i974D9D5DAD0DB96A
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F6XX57F6XX57_MOUSE
DNA topoisomerase 2-beta
Top2b
348Annotation score:
F6U5K2F6U5K2_MOUSE
DNA topoisomerase 2-beta
Top2b
230Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti16V → A in BAA07236 (Ref. 1) Curated1
Sequence conflicti1434L → P in BAA07236 (Ref. 1) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38046 mRNA Translation: BAA07236.1
BC041106 mRNA Translation: AAH41106.1
BC054541 mRNA Translation: AAH54541.1
CCDSiCCDS26833.1
RefSeqiNP_033435.2, NM_009409.2
UniGeneiMm.130362

Genome annotation databases

EnsembliENSMUST00000017629; ENSMUSP00000017629; ENSMUSG00000017485
GeneIDi21974
KEGGimmu:21974
UCSCiuc007shc.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D38046 mRNA Translation: BAA07236.1
BC041106 mRNA Translation: AAH41106.1
BC054541 mRNA Translation: AAH54541.1
CCDSiCCDS26833.1
RefSeqiNP_033435.2, NM_009409.2
UniGeneiMm.130362

3D structure databases

ProteinModelPortaliQ64511
SMRiQ64511
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi204277, 9 interactors
IntActiQ64511, 7 interactors
MINTiQ64511
STRINGi10090.ENSMUSP00000017629

Chemistry databases

ChEMBLiCHEMBL5564

PTM databases

iPTMnetiQ64511
PhosphoSitePlusiQ64511

Proteomic databases

EPDiQ64511
MaxQBiQ64511
PaxDbiQ64511
PeptideAtlasiQ64511
PRIDEiQ64511

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000017629; ENSMUSP00000017629; ENSMUSG00000017485
GeneIDi21974
KEGGimmu:21974
UCSCiuc007shc.1 mouse

Organism-specific databases

CTDi7155
MGIiMGI:98791 Top2b

Phylogenomic databases

eggNOGiKOG0355 Eukaryota
COG0187 LUCA
COG0188 LUCA
GeneTreeiENSGT00390000016222
HOGENOMiHOG000216693
HOVERGENiHBG052998
InParanoidiQ64511
KOiK03164
OMAiDCASARY
OrthoDBiEOG091G00U2
PhylomeDBiQ64511
TreeFamiTF105282

Enzyme and pathway databases

ReactomeiR-MMU-4615885 SUMOylation of DNA replication proteins

Miscellaneous databases

PROiPR:Q64511
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000017485 Expressed in 296 organ(s), highest expression level in brain
CleanExiMM_TOP2B
ExpressionAtlasiQ64511 baseline and differential
GenevisibleiQ64511 MM

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
cd00187 TOP4c, 1 hit
cd03365 TOPRIM_TopoIIA, 1 hit
Gene3Di1.10.268.10, 1 hit
3.30.230.10, 1 hit
3.30.565.10, 1 hit
3.40.50.670, 1 hit
3.90.199.10, 1 hit
InterProiView protein in InterPro
IPR012542 DTHCT
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR001241 Topo_IIA
IPR013760 Topo_IIA-like_dom_sf
IPR002205 Topo_IIA_A/C
IPR013758 Topo_IIA_A/C_ab
IPR013757 Topo_IIA_A_a_sf
IPR013759 Topo_IIA_B_C
IPR013506 Topo_IIA_bsu_dom2
IPR018522 TopoIIA_CS
IPR031660 TOPRIM_C
IPR006171 TOPRIM_domain
IPR034157 TOPRIM_TopoII
PANTHERiPTHR10169 PTHR10169, 1 hit
PfamiView protein in Pfam
PF00204 DNA_gyraseB, 1 hit
PF00521 DNA_topoisoIV, 1 hit
PF08070 DTHCT, 1 hit
PF02518 HATPase_c, 1 hit
PF01751 Toprim, 1 hit
PF16898 TOPRIM_C, 1 hit
SMARTiView protein in SMART
SM00433 TOP2c, 1 hit
SM00434 TOP4c, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
SSF55874 SSF55874, 1 hit
SSF56719 SSF56719, 1 hit
PROSITEiView protein in PROSITE
PS00177 TOPOISOMERASE_II, 1 hit
PS50880 TOPRIM, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiTOP2B_MOUSE
AccessioniPrimary (citable) accession number: Q64511
Secondary accession number(s): Q7TQG4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: September 27, 2005
Last modified: November 7, 2018
This is version 175 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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