Atp7b

Functionⁱ

Copper ion transmembrane transporter involved in the export of copper out of the cells, such as the efflux of hepatic copper into the bile.By similarity

Catalytic activityⁱ

ATP + H₂O + Cu⁺(Side 1) = ADP + phosphate + Cu⁺(Side 2).By similarity

Sites

Feature key	Position(s)	DescriptionActions	Length
Metal bindingⁱ	79	Copper 1PROSITE-ProRule annotation	1
Metal bindingⁱ	82	Copper 1PROSITE-ProRule annotation	1
Metal bindingⁱ	164	Copper 2PROSITE-ProRule annotation	1
Metal bindingⁱ	167	Copper 2PROSITE-ProRule annotation	1
Metal bindingⁱ	278	Copper 3PROSITE-ProRule annotation	1
Metal bindingⁱ	281	Copper 3PROSITE-ProRule annotation	1
Metal bindingⁱ	372	Copper 4PROSITE-ProRule annotation	1
Metal bindingⁱ	501	Copper 5PROSITE-ProRule annotation	1
Metal bindingⁱ	504	Copper 5PROSITE-ProRule annotation	1
Metal bindingⁱ	577	Copper 6PROSITE-ProRule annotation	1
Metal bindingⁱ	580	Copper 6PROSITE-ProRule annotation	1
Active siteⁱ	1029	4-aspartylphosphate intermediateBy similarity	1
Metal bindingⁱ	1264	MagnesiumPROSITE-ProRule annotation	1
Metal bindingⁱ	1268	MagnesiumPROSITE-ProRule annotation	1

GO - Molecular functionⁱ

ATP binding Source: HGNC
copper-exporting ATPase activity
Source: MGI
Inferred from direct assayⁱ
- 15634671
copper ion binding Source: HGNC
copper ion transmembrane transporter activity Source: MGI
copper-transporting ATPase activity
Source: MGI
Inferred from direct assayⁱ
- 11237756
zinc ion binding Source: MGI

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Hydrolase
Biological process	Copper transport, Ion transport, Transport
Ligand	ATP-binding, Copper, Magnesium, Metal-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAⁱ	3.6.3.4 3474
Reactomeⁱ	R-MMU-936837 Ion transport by P-type ATPases

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Copper-transporting ATPase 2 (EC:3.6.3.54By similarity) Alternative name(s): Copper pump 2 Wilson disease-associated protein homolog
Gene namesⁱ	Name:Atp7b Synonyms:Wnd
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 8

Organism-specific databases

MGIⁱ	MGI:103297 Atp7b

Topology

Feature key	Position(s)	DescriptionActions	Length
Topological domainⁱ	1 – 655	CytoplasmicSequence analysisAdd BLAST	655
Transmembraneⁱ	656 – 677	HelicalSequence analysisAdd BLAST	22
Topological domainⁱ	678 – 699	ExtracellularSequence analysisAdd BLAST	22
Transmembraneⁱ	700 – 719	HelicalSequence analysisAdd BLAST	20
Topological domainⁱ	720 – 726	CytoplasmicSequence analysis	7
Transmembraneⁱ	727 – 747	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	748 – 766	ExtracellularSequence analysisAdd BLAST	19
Transmembraneⁱ	767 – 787	HelicalSequence analysisAdd BLAST	21
Topological domainⁱ	788 – 921	CytoplasmicSequence analysisAdd BLAST	134
Transmembraneⁱ	922 – 944	HelicalSequence analysisAdd BLAST	23
Topological domainⁱ	945 – 974	ExtracellularSequence analysisAdd BLAST	30
Transmembraneⁱ	975 – 996	HelicalSequence analysisAdd BLAST	22
Topological domainⁱ	997 – 1319	CytoplasmicSequence analysisAdd BLAST	323
Transmembraneⁱ	1320 – 1337	HelicalSequence analysisAdd BLAST	18
Topological domainⁱ	1338 – 1348	ExtracellularSequence analysisAdd BLAST	11
Transmembraneⁱ	1349 – 1368	HelicalSequence analysisAdd BLAST	20
Topological domainⁱ	1369 – 1462	CytoplasmicSequence analysisAdd BLAST	94

Keywords - Cellular componentⁱ

Endosome, Golgi apparatus, Membrane

Pathology & Biotechⁱ

Involvement in diseaseⁱ

Defects in Atp7b are the cause of the toxic milk mouse mutant (tx) phenotype, characterized by accumulation of copper in the liver in a manner similar to that observed in patients with Wilson disease.1 Publication

Keywords - Diseaseⁱ

Disease mutation

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000046315	1 – 1462	Copper-transporting ATPase 2Add BLAST		1462

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	478	PhosphoserineBy similarity	1
Modified residueⁱ	483	PhosphoserineBy similarity	1
Modified residueⁱ	1395	PhosphoserineBy similarity	1
Modified residueⁱ	1454	PhosphoserineBy similarity	1

Keywords - PTMⁱ

Phosphoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q64446
PaxDbⁱ	Q64446
PRIDEⁱ	Q64446

PTM databases

iPTMnetⁱ	Q64446
PhosphoSitePlusⁱ	Q64446

Expressionⁱ

Tissue specificityⁱ

Detected in liver and kidney.

Gene expression databases

Bgeeⁱ	ENSMUSG00000006567 Expressed in 123 organ(s), highest expression level in stomach
CleanExⁱ	MM_ATP7B
ExpressionAtlasⁱ	Q64446 baseline and differential
Genevisibleⁱ	Q64446 MM

Interactionⁱ

Subunit structureⁱ

Monomer. Interacts with COMMD1/MURR1 (By similarity). Interacts with DCTN4, in a copper-dependent manner (By similarity). Interacts with ATOX1 (By similarity). Interacts (via C-terminus) with ZBTB16/PLZF (By similarity).By similarity

Protein-protein interaction databases

BioGridⁱ	198269, 1 interactor
IntActⁱ	Q64446, 1 interactor
Molecular INTeraction database More...MINTⁱ	Q64446
STRINGⁱ	10090.ENSMUSP00000006742

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q64446
SMRⁱ	Q64446
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	69 – 135	HMA 1PROSITE-ProRule annotationAdd BLAST	67
Domainⁱ	154 – 220	HMA 2PROSITE-ProRule annotationAdd BLAST	67
Domainⁱ	268 – 334	HMA 3PROSITE-ProRule annotationAdd BLAST	67
Domainⁱ	362 – 428	HMA 4PROSITE-ProRule annotationAdd BLAST	67
Domainⁱ	491 – 557	HMA 5PROSITE-ProRule annotationAdd BLAST	67
Domainⁱ	567 – 633	HMA 6PROSITE-ProRule annotationAdd BLAST	67

Domainⁱ

Each HMA domain can bind a copper ion, they are tightly packed and closely interact with each other. Wild-type ATP7B can usually be loaded with an average 5.5 copper atoms per molecule (By similarity).By similarity

Sequence similaritiesⁱ

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily. [View classification]Curated

Keywords - Domainⁱ

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGⁱ	KOG0207 Eukaryota COG2217 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063773
HOGENOMⁱ	HOG000250397
HOVERGENⁱ	HBG050616
InParanoidⁱ	Q64446
KEGG Orthology (KO) More...KOⁱ	K17686
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G022E
TreeFamⁱ	TF300460

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd00371 HMA, 6 hits
Gene3Dⁱ	3.40.1110.10, 1 hit
InterProⁱ	View protein in InterPro IPR023299 ATPase_P-typ_cyto_dom_N IPR018303 ATPase_P-typ_P_site IPR023298 ATPase_P-typ_TM_dom_sf IPR008250 ATPase_P-typ_transduc_dom_A_sf IPR036412 HAD-like_sf IPR017969 Heavy-metal-associated_CS IPR006122 HMA_Cu_ion-bd IPR006121 HMA_dom IPR036163 HMA_dom_sf IPR027256 P-typ_ATPase_IB IPR001757 P_typ_ATPase
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00403 HMA, 6 hits
SUPFAMⁱ	SSF55008 SSF55008, 6 hits SSF56784 SSF56784, 1 hit SSF81653 SSF81653, 1 hit SSF81665 SSF81665, 1 hit
TIGRFAMsⁱ	TIGR01525 ATPase-IB_hvy, 1 hit TIGR01494 ATPase_P-type, 2 hits TIGR00003 TIGR00003, 5 hits
PROSITEⁱ	View protein in PROSITE PS00154 ATPASE_E1_E2, 1 hit PS01047 HMA_1, 5 hits PS50846 HMA_2, 6 hits

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show all Align All

Q64446-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MDPRKNLASV GTMPEQERQV TAKEASRKIL SKLALPGRPW EQSMKQSFAF 
        60         70         80         90        100
DNVGYEGGLD STSSSPAATD VVNILGMTCH SCVKSIEDRI SSLKGIVNIK 
       110        120        130        140        150
VSLEQGSATV RYVPSVMNLQ QICLQIEDMG FEASAAEGKA ASWPSRSSPA 
       160        170        180        190        200
QEAVVKLRVE GMTCQSCVSS IEGKIRKLQG VVRIKVSLSN QEAVITYQPY 
       210        220        230        240        250
LIQPEDLRDH ICDMGFEAAI KNRTAPLRLG PIDVNKLEST NLKKETVSPV 
       260        270        280        290        300
QISNHFETLG HQGSYLATLP LRIDGMHCKS CVLNIEGNIG QLPGVQNIHV 
       310        320        330        340        350
SLENKTAQIQ YDPSCVTPMF LQTAIEALPP GHFKVSLPDG VEENEPQSGS 
       360        370        380        390        400
SQRHQEQGPG RTAVLTISGI TCASSVQPIE DMLSQRKGVQ QTSISLAEGT 
       410        420        430        440        450
GAVLYDPSIV SLDELRTAVE DMGFEVSVNS ETFTINPVRN FKSGNSVPQT 
       460        470        480        490        500
MGDIAGSVQK MAPDTRGLPT HQGPGHSSET PSSPGATASQ KCFVQIKGMT 
       510        520        530        540        550
CASCVSNIER SLQRHAGILS VLVALMSGKA EVKYDPEIIQ SPRIAQLIQD 
       560        570        580        590        600
LGFEASVMED NTVSEGDIEL IITGMTCASC VHNIESKLTR TNGITYASVA 
       610        620        630        640        650
LATSKAHVKF DPEIVGPRDI IKIIEEIGFH ASLAQRNPNA HHLDHKTEIK 
       660        670        680        690        700
QWKKSFLCSL VFGIPVMGLM VYMLIPSSTP QETMVLDHNI IPGLSVLNLI 
       710        720        730        740        750
FFILCTFVQF LGGWYFYVQA YKSLRHRSAN MDVLIVLATT IAYAYSLVIL 
       760        770        780        790        800
VVAVAEKAEK SPVTFFDTPP MLFVFIALGR WLEHVAKSKT SEALAKLMSL 
       810        820        830        840        850
QATEATVVTL GEDNLILREE QVPMELVQRG DVIKVVPGGK FPVDGKVLEG 
       860        870        880        890        900
NTMADESLIT GEAMPVTKKP GSIVIAGSIN AHGSVLLKAT HVGNDTTLAQ 
       910        920        930        940        950
IVKLVEEAQM SKAPIQQLAD RFSGYFVPFI IIISTLTLVV WIVIGFVDFG 
       960        970        980        990       1000
VVQKYFPSPS KHISQTEVII RFAFQTSITV LCIACPCSLG LATPTAVMVG 
      1010       1020       1030       1040       1050
TGVAAQNGVL IKGGKPLEMA HKIKTVMFDK TGTITHGVPR VMRFLLLADV 
      1060       1070       1080       1090       1100
ATLPLRKVLA VVGTAEASSE HPLGVAVTKY CKEELGTETL GYSTDFQAVP 
      1110       1120       1130       1140       1150
GCGISCKVSN VEGILARSDL TAHPVGVGNP PTGEGAGPQT FSVLIGNREW 
      1160       1170       1180       1190       1200
MRRNGLTISS DISDAMTDHE MKGQTAILVA IDGVLCGMIA IADAVKPEAA 
      1210       1220       1230       1240       1250
LAIYTLKSMG VDVALITGDN RKTARAIATQ VGINKVFAEV LPSHKVAKVQ 
      1260       1270       1280       1290       1300
ELQNEGKKVA MVGDGVNDSP ALAQADVGIA IGTGTDVAIE AADVVLIRND 
      1310       1320       1330       1340       1350
LLDVVASIHL SKRTVRRIRV NLVLALIYNM VGIPIAAGVF MPIGIVLQPW 
      1360       1370       1380       1390       1400
MGSAAMAASS VSVVLSSLQL KCYRKPDLER YEAQAHGRMK PLSASQVSVH 
      1410       1420       1430       1440       1450
IGMDDRRRDS PRATAWDQVS YVSQVSLSSL TSDRLSRHGG AAEDGGDKWS 
      1460 
LLLSDRDEEQ CI

Length:1,462

Mass (Da):157,190

Last modified:July 27, 2011 - v2

Checksum:ⁱBEC219F80EB74214

GO

Computationally mapped potential isoform sequencesⁱ

There is 1 potential isoform mapped to this entry.BLAST Align Show all Add to basket

	Entry	Entry name		Protein names	Gene names	Length	Annotation

	B1AQ57	B1AQ57_MOUSE		Copper-transporting ATPase 2 Copper-transporting ATPase 2	Atp7b	1,347	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	107 – 108	SA → KH in AAC52852 (PubMed:8894697).Curated		2

Natural variant

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Natural variantⁱ	1356	M → V in tx mice.		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U38477 mRNA Translation: AAC52852.1 AL590619, AC163439 Genomic DNA Translation: CAM22052.1 CH466580 Genomic DNA Translation: EDL32910.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS22168.1
NCBI Reference Sequences More...RefSeqⁱ	NP_031537.2, NM_007511.2
UniGeneⁱ	Mm.87854

Genome annotation databases

Ensemblⁱ	ENSMUST00000006742; ENSMUSP00000006742; ENSMUSG00000006567
GeneIDⁱ	11979
KEGGⁱ	mmu:11979
UCSC genome browser More...UCSCⁱ	uc009lck.1 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q64446	Copper-transporting ATPase 2		RAT		1451	UniRef90_Q64535
UPI0003D6EA5E		MOUSE		1511
UPI000A30A045		MUSPA		1468
Isoform Short of Copper-transporting ATPase 2		RAT		663
Isoform PINAM2 of Copper-transporting ATPase 2		RAT		637
+4

Protein	Similar proteins		Species	Score	Length	Source
Q64446	Copper-transporting ATPase 2	)	HUMAN		1465	UniRef50_P35670
Copper-transporting ATPase 2		SHEEP		1505
Copper-transporting ATPase 2		RAT		1451
Uncharacterized protein		MACMU		1531
Uncharacterized protein		RHIBE		1531
+640

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U38477 mRNA Translation: AAC52852.1 AL590619, AC163439 Genomic DNA Translation: CAM22052.1 CH466580 Genomic DNA Translation: EDL32910.1
CCDSⁱ	CCDS22168.1
RefSeqⁱ	NP_031537.2, NM_007511.2
UniGeneⁱ	Mm.87854

3D structure databases

ProteinModelPortalⁱ	Q64446
SMRⁱ	Q64446
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	198269, 1 interactor
IntActⁱ	Q64446, 1 interactor
MINTⁱ	Q64446
STRINGⁱ	10090.ENSMUSP00000006742

PTM databases

iPTMnetⁱ	Q64446
PhosphoSitePlusⁱ	Q64446

Proteomic databases

MaxQBⁱ	Q64446
PaxDbⁱ	Q64446
PRIDEⁱ	Q64446

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000006742; ENSMUSP00000006742; ENSMUSG00000006567
GeneIDⁱ	11979
KEGGⁱ	mmu:11979
UCSCⁱ	uc009lck.1 mouse

Organism-specific databases

CTDⁱ	540
MGIⁱ	MGI:103297 Atp7b

Phylogenomic databases

eggNOGⁱ	KOG0207 Eukaryota COG2217 LUCA
GeneTreeⁱ	ENSGT00530000063773
HOGENOMⁱ	HOG000250397
HOVERGENⁱ	HBG050616
InParanoidⁱ	Q64446
KOⁱ	K17686
OrthoDBⁱ	EOG091G022E
TreeFamⁱ	TF300460

Enzyme and pathway databases

BRENDAⁱ	3.6.3.4 3474
Reactomeⁱ	R-MMU-936837 Ion transport by P-type ATPases

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q64446
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000006567 Expressed in 123 organ(s), highest expression level in stomach
CleanExⁱ	MM_ATP7B
ExpressionAtlasⁱ	Q64446 baseline and differential
Genevisibleⁱ	Q64446 MM

Family and domain databases

CDDⁱ	cd00371 HMA, 6 hits
Gene3Dⁱ	3.40.1110.10, 1 hit
InterProⁱ	View protein in InterPro IPR023299 ATPase_P-typ_cyto_dom_N IPR018303 ATPase_P-typ_P_site IPR023298 ATPase_P-typ_TM_dom_sf IPR008250 ATPase_P-typ_transduc_dom_A_sf IPR036412 HAD-like_sf IPR017969 Heavy-metal-associated_CS IPR006122 HMA_Cu_ion-bd IPR006121 HMA_dom IPR036163 HMA_dom_sf IPR027256 P-typ_ATPase_IB IPR001757 P_typ_ATPase
Pfamⁱ	View protein in Pfam PF00403 HMA, 6 hits
SUPFAMⁱ	SSF55008 SSF55008, 6 hits SSF56784 SSF56784, 1 hit SSF81653 SSF81653, 1 hit SSF81665 SSF81665, 1 hit
TIGRFAMsⁱ	TIGR01525 ATPase-IB_hvy, 1 hit TIGR01494 ATPase_P-type, 2 hits TIGR00003 TIGR00003, 5 hits
PROSITEⁱ	View protein in PROSITE PS00154 ATPASE_E1_E2, 1 hit PS01047 HMA_1, 5 hits PS50846 HMA_2, 6 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	ATP7B_MOUSE
Accessionⁱ	Q64446Primary (citable) accession number: Q64446 Secondary accession number(s): B1AQ56
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 8, 2000
	Last sequence update:	July 27, 2011
	Last modified:	November 7, 2018
	This is version 174 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

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Help

UniRef

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Supporting data

UniProtKB - Q64446 (ATP7B_MOUSE)

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Copper-transporting ATPase 2

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Golgi apparatus

Endosome

Endoplasmic reticulum

Endosome

Golgi apparatus

Plasma Membrane

Other locations

Topology

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Keywords - Diseasei

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Natural variant

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

Keywords - Diseaseⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ