Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 156 (16 Oct 2019)
Sequence version 2 (31 Oct 2012)
Previous versions | rss
Help videoAdd a publicationFeedback
Protein

Killer cell lectin-like receptor 3

Gene

Klra3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor on natural killer (NK) cells for class I MHC.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionReceptor
Biological processCell adhesion
LigandLectin

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Killer cell lectin-like receptor 3
Alternative name(s):
5E6
Lymphocyte antigen 49c
Short name:
Ly-49c
Nk2.1
T-cell surface glycoprotein Ly-49C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Klra3
Synonyms:Ly-49c, Ly49C
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:101905 Klra3

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 48CytoplasmicSequence analysisAdd BLAST48
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei49 – 69Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini70 – 266ExtracellularSequence analysisAdd BLAST197

Keywords - Cellular componenti

Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi121R → G: Increases stability and improves binding to MHC I class ligand; when associated with G-175; G-197 and K-227. 1 Publication1
Mutagenesisi160N → D: Greatly reduces MHC class I peptide tetramer binding; when associated with L-162. 1 Publication1
Mutagenesisi161K → R: No effect on MHC class I peptide tetramer binding. 1 Publication1
Mutagenesisi162T → K: Greatly reduces MHC class I peptide tetramer binding; when associated with D-160. 1 Publication1
Mutagenesisi169A → Q: No effect on MHC class I peptide tetramer binding; when associated with T-170. 1 Publication1
Mutagenesisi170N → T: No effect on MHC class I peptide tetramer binding; when associated with Q-169. 1 Publication1
Mutagenesisi173H → S: No effect on MHC class I peptide tetramer binding; when associated with S-174. 1 Publication1
Mutagenesisi174Y → S: No effect on MHC class I binding; when associated with S-173. 1 Publication1
Mutagenesisi175S → G: Increases stability. Increases stability and improves binding to MHC I class ligand; when associated with G-121; G-197 and K-227. 1 Publication1
Mutagenesisi195I → P: Greatly reduces MHC class I peptide tetramer binding; when associated with S-196. 1 Publication1
Mutagenesisi196P → S: Greatly reduces MHC class I peptide tetramer binding; when associated with P-195. 1 Publication1
Mutagenesisi197E → G: Increases stability and improves binding to MHC I class ligand; when associated with G-121; G-175 and K-227. 1 Publication1
Mutagenesisi225K → N: Greatly reduces MHC class I peptide tetramer binding; when associated with T-226. 1 Publication1
Mutagenesisi226I → T: Greatly reduces MHC class I peptide tetramer binding; when associated with N-225. 1 Publication1
Mutagenesisi227R → K: Increases stability and improves binding to MHC I class ligand; when associated with G-121; G-175 and G-197. 1 Publication1
Mutagenesisi234R → G: No effect on MHC class I peptide tetramer binding. 1 Publication1
Mutagenesisi248D → N: No effect on MHC class I peptide tetramer binding; when associated with D-250. 1 Publication1
Mutagenesisi250N → D: No effect on MHC class I peptide tetramer binding; when associated with N-248. 1 Publication1
Mutagenesisi251I → Q: No effect on MHC class I peptide tetramer binding. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000466811 – 266Killer cell lectin-like receptor 3Add BLAST266

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi79N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi87N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi104N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi113N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi149 ↔ 154
Glycosylationi160N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi167 ↔ 255
Disulfide bondi171 ↔ 257
Disulfide bondi236 ↔ 249

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q64329

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q64329

PRoteomics IDEntifications database

More...
PRIDEi
Q64329

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000067591 Expressed in 12 organ(s), highest expression level in thymus

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q64329 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer; disulfide-linked.

2 Publications

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
200995, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000107629

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1266
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q64329

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q64329

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini150 – 258C-type lectinPROSITE-ProRule annotationAdd BLAST109

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni147 – 151Involved in dimerization5
Regioni160 – 162Implicated in MHC class I binding3
Regioni195 – 196Implicated in MHC class I binding2
Regioni207 – 208Implicated in MHC class I binding2
Regioni224 – 233Implicated in MHC class I binding10
Regioni240 – 245Implicated in MHC class I binding6

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4297 Eukaryota
ENOG410XPJ1 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000008117

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000113237

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q64329

Identification of Orthologs from Complete Genome Data

More...
OMAi
NEIETHW

Database of Orthologous Groups

More...
OrthoDBi
1180904at2759

TreeFam database of animal gene trees

More...
TreeFami
TF336674

Family and domain databases

Conserved Domains Database

More...
CDDi
cd03593 CLECT_NK_receptors_like, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.10.100.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
IPR013600 Ly49_N
IPR033992 NKR-like_CTLD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00059 Lectin_C, 1 hit
PF08391 Ly49, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00034 CLECT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56436 SSF56436, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50041 C_TYPE_LECTIN_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q64329-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSEPEVTYST VRLHKSSGLQ KLVRHEETQG PREVGNRKCS APWQLIVKAL
60 70 80 90 100
GILCFLLLVT VAVLAVKIFQ YNQHKQEINE TLNHHHNCSN MQRAFNLKEE
110 120 130 140 150
MLTNKSIDCR PSNETLEYIK REQDRWDSKT KTVLDSSRDT GRGVKYWFCY
160 170 180 190 200
STKCYYFIMN KTTWSGCKAN CQHYSVPILK IEDEDELKFL QRHVIPENYW
210 220 230 240 250
IGLSYDKKKK EWAWIDNGPS KLDMKIRKMN FKSRGCVFLS KARIEDIDCN
260
IPYYCICGKK LDKFPD
Length:266
Mass (Da):31,311
Last modified:October 31, 2012 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iBF9B10D9B6EFD628
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti4P → L in AAH99880 (PubMed:15489334).Curated1
Sequence conflicti4P → L in AAH99879 (PubMed:15489334).Curated1
Sequence conflicti4P → L in AAH99878 (PubMed:15489334).Curated1
Sequence conflicti4P → L in AAH99867 (PubMed:15489334).Curated1
Sequence conflicti162T → M in BAE35215 (PubMed:16141072).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti2S → N in strain: C57BL/6 and C57BL/6 X BALB/c. 1
Natural varianti22L → Q in strain: A/Sn, BALB/c, C57BL/6, C57BL/6 X BALB/c, C57BL/6 X CBA, CB-17/SCID and NZB. 1
Natural varianti34V → A in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti41 – 42AP → VS in strain: C57BL/6 X BALB/c, NZB and C57BL/6. 2
Natural varianti60T → I in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti65 – 66AV → TI in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 2
Natural varianti72N → S in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti85H → Y in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti93 – 94RA → SD in strain: A/Sn, BALB/c, C57BL/6, C57BL/6 X BALB/c, C57BL/6 X CBA, CB-17/SCID and NZB. 2
Natural varianti115T → L in strain: C57BL/6, C57BL/6 X BALB/c and NZB; requires 2 nucleotide substitutions. 1
Natural varianti117E → D in strain: C57BL/6 and C57BL/6 X BALB/c. 1
Natural varianti127D → N in strain: C57BL/6 and C57BL/6 X BALB/c. 1
Natural varianti129K → E in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti131K → N in strain: NZB. 1
Natural varianti133V → I in strain: NZB. 1
Natural varianti146Y → H in strain: C57BL/6 and C57BL/6 X BALB/c. 1
Natural varianti151S → G in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti174Y → F in strain: A/Sn, BALB/c, C57BL/6, C57BL/6 X BALB/c, C57BL/6 X CBA, CB-17/SCID and NZB. 1
Natural varianti179L → V in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti189F → S in strain: NZB. 1
Natural varianti198N → S in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti219P → Q in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti226I → T in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti232K → T in strain: NZB. 1
Natural varianti247I → T in strain: C57BL/6, C57BL/6 X BALB/c and NZB. 1
Natural varianti251I → T in strain: NZB. 1
Natural varianti260K → R in strain: NZB. 1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U10305 mRNA Translation: AAA19053.1
U09739 mRNA Translation: AAA86873.1
U49865 mRNA Translation: AAA92951.1
U49866 mRNA Translation: AAA92952.1
U49867 mRNA Translation: AAA92953.1
U49868 mRNA Translation: AAA92954.1
U56404 mRNA Translation: AAB19100.1
U56405 mRNA Translation: AAB19101.1
AK159595 mRNA Translation: BAE35215.1
AC087336 Genomic DNA No translation available.
BC099867 mRNA Translation: AAH99867.1
BC099878 mRNA Translation: AAH99878.1
BC099879 mRNA Translation: AAH99879.1
BC099880 mRNA Translation: AAH99880.1
BC101952 mRNA Translation: AAI01953.1
BC103543 mRNA Translation: AAI03544.1
BC103544 mRNA Translation: AAI03545.1
BC103545 mRNA Translation: AAI03546.1
BC132524 mRNA Translation: AAI32525.1
BC132526 mRNA Translation: AAI32527.1
BC145192 mRNA Translation: AAI45193.1
BC145193 mRNA Translation: AAI45194.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS20601.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I49059
I49363

NCBI Reference Sequences

More...
RefSeqi
NP_001276533.1, NM_001289604.1
NP_001276534.1, NM_001289605.1
NP_034778.2, NM_010648.3
NP_034781.2, NM_010651.3
XP_011239535.1, XM_011241233.1
XP_011239537.1, XM_011241235.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000088017; ENSMUSP00000085333; ENSMUSG00000067591
ENSMUST00000111998; ENSMUSP00000107629; ENSMUSG00000067591

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
16634
16640

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:16634
mmu:16640

UCSC genome browser

More...
UCSCi
uc009eik.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U10305 mRNA Translation: AAA19053.1
U09739 mRNA Translation: AAA86873.1
U49865 mRNA Translation: AAA92951.1
U49866 mRNA Translation: AAA92952.1
U49867 mRNA Translation: AAA92953.1
U49868 mRNA Translation: AAA92954.1
U56404 mRNA Translation: AAB19100.1
U56405 mRNA Translation: AAB19101.1
AK159595 mRNA Translation: BAE35215.1
AC087336 Genomic DNA No translation available.
BC099867 mRNA Translation: AAH99867.1
BC099878 mRNA Translation: AAH99878.1
BC099879 mRNA Translation: AAH99879.1
BC099880 mRNA Translation: AAH99880.1
BC101952 mRNA Translation: AAI01953.1
BC103543 mRNA Translation: AAI03544.1
BC103544 mRNA Translation: AAI03545.1
BC103545 mRNA Translation: AAI03546.1
BC132524 mRNA Translation: AAI32525.1
BC132526 mRNA Translation: AAI32527.1
BC145192 mRNA Translation: AAI45193.1
BC145193 mRNA Translation: AAI45194.1
CCDSiCCDS20601.1
PIRiI49059
I49363
RefSeqiNP_001276533.1, NM_001289604.1
NP_001276534.1, NM_001289605.1
NP_034778.2, NM_010648.3
NP_034781.2, NM_010651.3
XP_011239535.1, XM_011241233.1
XP_011239537.1, XM_011241235.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1P1ZX-ray3.26D143-262[»]
1P4LX-ray2.90D142-263[»]
3C8JX-ray2.60A/B/C/D67-266[»]
3C8KX-ray2.90D142-266[»]
5J6GX-ray3.30G/H136-266[»]
SMRiQ64329
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi200995, 1 interactor
STRINGi10090.ENSMUSP00000107629

Proteomic databases

EPDiQ64329
PaxDbiQ64329
PRIDEiQ64329

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
16640

Genome annotation databases

EnsembliENSMUST00000088017; ENSMUSP00000085333; ENSMUSG00000067591
ENSMUST00000111998; ENSMUSP00000107629; ENSMUSG00000067591
GeneIDi16634
16640
KEGGimmu:16634
mmu:16640
UCSCiuc009eik.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
16634
16640
MGIiMGI:101905 Klra3

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00390000008117
HOGENOMiHOG000113237
InParanoidiQ64329
OMAiNEIETHW
OrthoDBi1180904at2759
TreeFamiTF336674

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Klra3 mouse
EvolutionaryTraceiQ64329

Protein Ontology

More...
PROi
PR:Q64329

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000067591 Expressed in 12 organ(s), highest expression level in thymus
GenevisibleiQ64329 MM

Family and domain databases

CDDicd03593 CLECT_NK_receptors_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR016187 CTDL_fold
IPR013600 Ly49_N
IPR033992 NKR-like_CTLD
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
PF08391 Ly49, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS50041 C_TYPE_LECTIN_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKLRA3_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q64329
Secondary accession number(s): Q3TWQ1
, Q3ZB40, Q499I4, Q61154, Q61198, Q64257
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: October 31, 2012
Last modified: October 16, 2019
This is version 156 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again