UniProtKB - Q64249 (NR6A1_MOUSE)

BLAST

>sp|Q64249|NR6A1_MOUSE Nuclear receptor subfamily 6 group A member 1 OS=Mus musculus OX=10090 GN=Nr6a1 PE=1 SV=1
MERDERPPSGGGGGGGSAGFLEPPAALPPPPRNGFCQDELAELDPGTNGETDSLTLGQGH
IPVSVPDDRAEQRTCLICGDRATGLHYGIISCEGCKGFFKRSICNKRVYRCSRDKNCVMS
RKQRNRCQYCRLLKCLQMGMNRKAIREDGMPGGRNKSIGPVQISEEEIERIMSGQEFEEE
ANHWSNHGDSDHSSPGNRASESNQPSPGSTLSSSRSVELNGFMAFRDQYMGMSVPPHYQY
IPHLFSYSGHSPLLPPQARSLDPQSYSLIHQLMSAEDLEPLGTPMLIEDGYAVTQAELFA
LLCRLADELLFRQIAWIKKLPFFCELSIKDYTCLLSSTWQELILLSSLTVYSKQIFGELA
DVTAKYSPSDEELHRFSDEGMEVIERLIYLYHKFHQLKVSNEEYACMKAINFLNQDIRGL
TSASQLEQLNKRYWYICQDFTEYKYTHQPNRFPDLMMCLPEIRYIAGKMVNVPLEQLPLL
FKVVLHSCKTSTVKE

Align

Format
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History
Entry version 160 (07 Nov 2018)
Sequence version 1 (01 Nov 1996)
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Protein

Nuclear receptor subfamily 6 group A member 1

Gene

Nr6a1

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Orphan nuclear receptor. Binds to a response element containing the sequence 5'-TCAAGGTCA-3'. May be involved in the regulation of gene expression in germ cell development during gametogenesis.1 Publication

Regions

Feature key	Position(s)	DescriptionActions	Length
DNA bindingⁱ	72 – 147	Nuclear receptorPROSITE-ProRule annotationAdd BLAST	76
Zinc fingerⁱ	75 – 95	NR C4-typePROSITE-ProRule annotationAdd BLAST	21
Zinc fingerⁱ	111 – 135	NR C4-typePROSITE-ProRule annotationAdd BLAST	25

GO - Molecular functionⁱ

DNA binding
Source: MGI
Inferred from direct assayⁱ
- 11702949
- 16166633
nuclear receptor activity
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
protein homodimerization activity
Source: UniProtKB
Inferred from direct assayⁱ
- 7854358
- 9025060
proximal promoter DNA-binding transcription activator activity, RNA polymerase II-specific
Source: NTNU_SB
Inferred from direct assayⁱ
- 9099702
RNA polymerase II proximal promoter sequence-specific DNA binding
Source: NTNU_SB
Inferred from mutant phenotypeⁱ
- 9099702
sequence-specific DNA binding
Source: UniProtKB
Inferred from direct assayⁱ
- 7854358
- 9025060
steroid hormone receptor activity Source: InterPro
zinc ion binding Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

cell differentiation Source: UniProtKB-KW
gamete generation
Source: UniProtKB
Inferred from expression patternⁱ
- 7835709
- 7854358
multicellular organism development Source: UniProtKB-KW
negative regulation of transcription by RNA polymerase II
Source: MGI
Inferred from direct assayⁱ
- 11702949
- 16166633
positive regulation of transcription by RNA polymerase II
Source: NTNU_SB
Inferred from direct assayⁱ
- 9099702
spermatogenesis Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Developmental protein, DNA-binding, Receptor
Biological process	Differentiation, Spermatogenesis, Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Enzyme and pathway databases

Reactomeⁱ	R-MMU-383280 Nuclear Receptor transcription pathway

Reactomeⁱ

R-MMU-383280 Nuclear Receptor transcription pathway

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: Nuclear receptor subfamily 6 group A member 1 Alternative name(s): Germ cell nuclear factor Short name: GCNF Short name: mGCNF Retinoid receptor-related testis-specific receptor Short name: RTR
Gene namesⁱ	Name:Nr6a1 Synonyms:Gcnf
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 2

Organism-specific databases

MGIⁱ	MGI:1352459 Nr6a1

Keywords - Cellular componentⁱ

Nucleus

Pathology & Biotechⁱ

Mutagenesis

Feature key	Position(s)	DescriptionActions	Length
Mutagenesisⁱ	246 – 247	SY → GG: Abolishes interaction with RXRIP110. 1 Publication	2
Mutagenesisⁱ	254 – 255	LP → AA: Does not abolish interaction with RXRIP110. 1 Publication	2
Mutagenesisⁱ	265 – 266	SY → AA: Does not abolish interaction with RXRIP110. 1 Publication	2

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000053742	1 – 495	Nuclear receptor subfamily 6 group A member 1Add BLAST		495

Proteomic databases

PaxDbⁱ	Q64249
PRIDEⁱ	Q64249

PTM databases

PhosphoSitePlusⁱ	Q64249

PhosphoSitePlusⁱ

Q64249

Expressionⁱ

Tissue specificityⁱ

Expressed in the germ cells of both the adult testis and ovary, being most abundant in spermatids.2 Publications

Gene expression databases

Bgeeⁱ	ENSMUSG00000063972 Expressed in 212 organ(s), highest expression level in primitive streak
CleanExⁱ	MM_NR6A1
ExpressionAtlasⁱ	Q64249 baseline and differential
Genevisibleⁱ	Q64249 MM

Interactionⁱ

Subunit structureⁱ

Homodimer. Interacts with UIMC1.2 Publications

GO - Molecular functionⁱ

protein homodimerization activity
Source: UniProtKB
Inferred from direct assayⁱ
- 7854358
- 9025060

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	199868, 5 interactors
STRINGⁱ	10090.ENSMUSP00000075624

Structureⁱ

Secondary structure

Legend: HelixTurnBeta strandPDB Structure known for this area

Feature key	Position(s)	DescriptionActions	Length
Turnⁱ	76 – 78	Combined sources	3
Beta strandⁱ	84 – 86	Combined sources	3
Helixⁱ	93 – 104	Combined sources	12
Turnⁱ	121 – 123	Combined sources	3
Helixⁱ	124 – 126	Combined sources	3
Helixⁱ	128 – 138	Combined sources	11
Helixⁱ	142 – 144	Combined sources	3

Show more details

3D structure databases

ProteinModelPortalⁱ	Q64249
SMRⁱ	Q64249
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	264 – 495	NR LBDPROSITE-ProRule annotationAdd BLAST		232

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	187 – 268	Sufficient for interaction with UIMC1Add BLAST		82

Sequence similaritiesⁱ

Belongs to the nuclear hormone receptor family. NR6 subfamily.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	75 – 95	NR C4-typePROSITE-ProRule annotationAdd BLAST		21
Zinc fingerⁱ	111 – 135	NR C4-typePROSITE-ProRule annotationAdd BLAST		25

Keywords - Domainⁱ

Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG3575 Eukaryota ENOG410XRZC LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00870000136388
HOGENOMⁱ	HOG000113847
HOVERGENⁱ	HBG052664
InParanoidⁱ	Q64249
KEGG Orthology (KO) More...KOⁱ	K08561
OMAⁱ	PVEAHTH
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G06MN
PhylomeDBⁱ	Q64249
TreeFamⁱ	TF350737

Family and domain databases

Gene3Dⁱ	3.30.50.10, 1 hit
InterProⁱ	View protein in InterPro IPR035500 NHR_like_dom_sf IPR000536 Nucl_hrmn_rcpt_lig-bd IPR001723 Nuclear_hrmn_rcpt IPR001628 Znf_hrmn_rcpt IPR013088 Znf_NHR/GATA
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00104 Hormone_recep, 1 hit PF00105 zf-C4, 1 hit
PRINTSⁱ	PR00398 STRDHORMONER PR00047 STROIDFINGER
SMARTⁱ	View protein in SMART SM00430 HOLI, 1 hit SM00399 ZnF_C4, 1 hit
SUPFAMⁱ	SSF48508 SSF48508, 1 hit
PROSITEⁱ	View protein in PROSITE PS51843 NR_LBD, 1 hit PS00031 NUCLEAR_REC_DBD_1, 1 hit PS51030 NUCLEAR_REC_DBD_2, 1 hit

Sequences (3+)ⁱ

Sequence statusⁱ: Complete.

This entry describes 3 isoformsⁱ produced by alternative splicing. Align Add to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show all Align All

Isoform 1 (identifier: Q64249-1) [UniParc]FASTA Add to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MERDERPPSG GGGGGGSAGF LEPPAALPPP PRNGFCQDEL AELDPGTNGE 
        60         70         80         90        100
TDSLTLGQGH IPVSVPDDRA EQRTCLICGD RATGLHYGII SCEGCKGFFK 
       110        120        130        140        150
RSICNKRVYR CSRDKNCVMS RKQRNRCQYC RLLKCLQMGM NRKAIREDGM 
       160        170        180        190        200
PGGRNKSIGP VQISEEEIER IMSGQEFEEE ANHWSNHGDS DHSSPGNRAS 
       210        220        230        240        250
ESNQPSPGST LSSSRSVELN GFMAFRDQYM GMSVPPHYQY IPHLFSYSGH 
       260        270        280        290        300
SPLLPPQARS LDPQSYSLIH QLMSAEDLEP LGTPMLIEDG YAVTQAELFA 
       310        320        330        340        350
LLCRLADELL FRQIAWIKKL PFFCELSIKD YTCLLSSTWQ ELILLSSLTV 
       360        370        380        390        400
YSKQIFGELA DVTAKYSPSD EELHRFSDEG MEVIERLIYL YHKFHQLKVS 
       410        420        430        440        450
NEEYACMKAI NFLNQDIRGL TSASQLEQLN KRYWYICQDF TEYKYTHQPN 
       460        470        480        490 
RFPDLMMCLP EIRYIAGKMV NVPLEQLPLL FKVVLHSCKT STVKE

Length:495

Mass (Da):55,976

Last modified:November 1, 1996 - v1

Checksum:ⁱECB0AB3E99E42661

Isoform 2 (identifier: Q64249-2) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
48-62: Missing.
63-63: V → I

« Hide

        10         20         30         40         50
MERDERPPSG GGGGGGSAGF LEPPAALPPP PRNGFCQDEL AELDPGTISV 
        60         70         80         90        100
PDDRAEQRTC LICGDRATGL HYGIISCEGC KGFFKRSICN KRVYRCSRDK 
       110        120        130        140        150
NCVMSRKQRN RCQYCRLLKC LQMGMNRKAI REDGMPGGRN KSIGPVQISE 
       160        170        180        190        200
EEIERIMSGQ EFEEEANHWS NHGDSDHSSP GNRASESNQP SPGSTLSSSR 
       210        220        230        240        250
SVELNGFMAF RDQYMGMSVP PHYQYIPHLF SYSGHSPLLP PQARSLDPQS 
       260        270        280        290        300
YSLIHQLMSA EDLEPLGTPM LIEDGYAVTQ AELFALLCRL ADELLFRQIA 
       310        320        330        340        350
WIKKLPFFCE LSIKDYTCLL SSTWQELILL SSLTVYSKQI FGELADVTAK 
       360        370        380        390        400
YSPSDEELHR FSDEGMEVIE RLIYLYHKFH QLKVSNEEYA CMKAINFLNQ 
       410        420        430        440        450
DIRGLTSASQ LEQLNKRYWY ICQDFTEYKY THQPNRFPDL MMCLPEIRYI 
       460        470        480
AGKMVNVPLE QLPLLFKVVL HSCKTSTVKE

Note: No experimental confirmation available.

Show »

Length:480

Mass (Da):54,469

Checksum:ⁱ17DA7AC5DB297A23

Isoform 3 (identifier: Q64249-3) [UniParc]FASTA Add to basket

The sequence of this isoform differs from the canonical sequence as follows:
1-57: Missing.
58-62: QGHIP → METWE

« Hide

        10         20         30         40         50
METWEVSVPD DRAEQRTCLI CGDRATGLHY GIISCEGCKG FFKRSICNKR 
        60         70         80         90        100
VYRCSRDKNC VMSRKQRNRC QYCRLLKCLQ MGMNRKAIRE DGMPGGRNKS 
       110        120        130        140        150
IGPVQISEEE IERIMSGQEF EEEANHWSNH GDSDHSSPGN RASESNQPSP 
       160        170        180        190        200
GSTLSSSRSV ELNGFMAFRD QYMGMSVPPH YQYIPHLFSY SGHSPLLPPQ 
       210        220        230        240        250
ARSLDPQSYS LIHQLMSAED LEPLGTPMLI EDGYAVTQAE LFALLCRLAD 
       260        270        280        290        300
ELLFRQIAWI KKLPFFCELS IKDYTCLLSS TWQELILLSS LTVYSKQIFG 
       310        320        330        340        350
ELADVTAKYS PSDEELHRFS DEGMEVIERL IYLYHKFHQL KVSNEEYACM 
       360        370        380        390        400
KAINFLNQDI RGLTSASQLE QLNKRYWYIC QDFTEYKYTH QPNRFPDLMM 
       410        420        430 
CLPEIRYIAG KMVNVPLEQL PLLFKVVLHS CKTSTVKE

Note: No experimental confirmation available.

Show »

Length:438

Mass (Da):50,445

Checksum:ⁱ78B62010C39F7310

Computationally mapped potential isoform sequencesⁱ

There are 2 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Z4YMW4	Z4YMW4_MOUSE	Nuclear receptor subfamily 6 group ... Nuclear receptor subfamily 6 group A member 1	Nr6a1	235	Annotation score:
A0A0A0MQG4	A0A0A0MQG4_MOUSE	Nuclear receptor subfamily 6 group ... Nuclear receptor subfamily 6 group A member 1	Nr6a1	220	Annotation score:

Alternative sequence

Feature key	Position(s)	DescriptionActions	Length
Alternative sequenceⁱVSP_025928	1 – 57	Missing in isoform 3. CuratedAdd BLAST	57
Alternative sequenceⁱVSP_025929	48 – 62	Missing in isoform 2. CuratedAdd BLAST	15
Alternative sequenceⁱVSP_025930	58 – 62	QGHIP → METWE in isoform 3. Curated	5
Alternative sequenceⁱVSP_025931	63	V → I in isoform 2. Curated	1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U14666 mRNA Translation: AAA92682.1 U09563 mRNA Translation: AAA64746.1 AF254821 AF254820 Genomic DNA Translation: AAG24485.1 AF390896 mRNA Translation: AAM55193.1 AF390900 , AF390897, AF390898, AF390899 Genomic DNA Translation: AAM95878.1 AL844842, AL935155 Genomic DNA Translation: CAM21928.1 AL844842, AL935155 Genomic DNA Translation: CAM21929.1 AL844842 Genomic DNA Translation: CAM21933.1 AL935155, AL844842 Genomic DNA Translation: CAM21313.1 AL935155, AL844842 Genomic DNA Translation: CAM21314.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS16012.1 [Q64249-1] CCDS50581.1 [Q64249-3]
PIRⁱ	A57053
NCBI Reference Sequences More...RefSeqⁱ	NP_001153020.1, NM_001159548.1 [Q64249-3] NP_034394.1, NM_010264.4 [Q64249-1]
UniGeneⁱ	Mm.439703

Genome annotation databases

Ensemblⁱ	ENSMUST00000076275; ENSMUSP00000075624; ENSMUSG00000063972 [Q64249-1] ENSMUST00000112877; ENSMUSP00000108498; ENSMUSG00000063972 [Q64249-1] ENSMUST00000168098; ENSMUSP00000126009; ENSMUSG00000063972 [Q64249-3]
GeneIDⁱ	14536
KEGGⁱ	mmu:14536
UCSC genome browser More...UCSCⁱ	uc012bus.1 mouse [Q64249-3] uc012buu.1 mouse [Q64249-1]

Keywords - Coding sequence diversityⁱ

Alternative splicing

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q64249	Nuclear receptor subfamily 6 group A member 1		HUMAN		480	UniRef90_Q64249
Nuclear receptor subfamily 6 group A member 1		PIG		479
nuclear receptor subfamily 6 group A member 1 isoform X1		DELLE		497
nuclear receptor subfamily 6 group A member 1 isoform X2		Yangtze finless porpoise		376
nuclear receptor subfamily 6 group A member 1 isoform X5		Florida manatee		497
+185
Q64249-3	Nuclear receptor subfamily 6 group A member 1 (Fragment)		MOUSE		235	UniRef90_Q64249-3
Nuclear receptor subfamily 6 group A member 1		MYODS		508
Uncharacterized protein		AOTNA		457
Uncharacterized protein		MACFA		457
Uncharacterized protein		PANTR		455
+108

Protein	Similar proteins		Species	Score	Length	Source
Q64249	Nuclear receptor subfamily 6 group A member 1		HUMAN		480	UniRef50_Q64249
Nuclear receptor subfamily 6 group A member 1		PIG		479
Nuclear receptor subfamily 6 group A member 1-A		DANRE		477
nuclear receptor subfamily 6 group A member 1 isoform X5		Florida manatee		497
nuclear receptor subfamily 6 group A member 1 isoform X1		DELLE		497
+425

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	U14666 mRNA Translation: AAA92682.1 U09563 mRNA Translation: AAA64746.1 AF254821 AF254820 Genomic DNA Translation: AAG24485.1 AF390896 mRNA Translation: AAM55193.1 AF390900 , AF390897, AF390898, AF390899 Genomic DNA Translation: AAM95878.1 AL844842, AL935155 Genomic DNA Translation: CAM21928.1 AL844842, AL935155 Genomic DNA Translation: CAM21929.1 AL844842 Genomic DNA Translation: CAM21933.1 AL935155, AL844842 Genomic DNA Translation: CAM21313.1 AL935155, AL844842 Genomic DNA Translation: CAM21314.1
CCDSⁱ	CCDS16012.1 [Q64249-1] CCDS50581.1 [Q64249-3]
PIRⁱ	A57053
RefSeqⁱ	NP_001153020.1, NM_001159548.1 [Q64249-3] NP_034394.1, NM_010264.4 [Q64249-1]
UniGeneⁱ	Mm.439703

3D structure databases

Select the link destinations: Protein Data Bank Europe More...PDBeⁱ Protein Data Bank RCSB More...RCSB PDBⁱ Protein Data Bank Japan More...PDBjⁱ Links Updated	PDB entry	Method	Resolution (Å)	Chain	Positions	PDBsum
	5KRB	X-ray	2.10	B/G	72-155	[»]
ProteinModelPortalⁱ	Q64249
SMRⁱ	Q64249
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	199868, 5 interactors
STRINGⁱ	10090.ENSMUSP00000075624

PTM databases

PhosphoSitePlusⁱ	Q64249

PhosphoSitePlusⁱ

Q64249

Proteomic databases

PaxDbⁱ	Q64249
PRIDEⁱ	Q64249

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	14536
Structural Biology Knowledgebase	Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000076275; ENSMUSP00000075624; ENSMUSG00000063972 [Q64249-1] ENSMUST00000112877; ENSMUSP00000108498; ENSMUSG00000063972 [Q64249-1] ENSMUST00000168098; ENSMUSP00000126009; ENSMUSG00000063972 [Q64249-3]
GeneIDⁱ	14536
KEGGⁱ	mmu:14536
UCSCⁱ	uc012bus.1 mouse [Q64249-3] uc012buu.1 mouse [Q64249-1]

Organism-specific databases

CTDⁱ	2649
MGIⁱ	MGI:1352459 Nr6a1

Phylogenomic databases

eggNOGⁱ	KOG3575 Eukaryota ENOG410XRZC LUCA
GeneTreeⁱ	ENSGT00870000136388
HOGENOMⁱ	HOG000113847
HOVERGENⁱ	HBG052664
InParanoidⁱ	Q64249
KOⁱ	K08561
OMAⁱ	PVEAHTH
OrthoDBⁱ	EOG091G06MN
PhylomeDBⁱ	Q64249
TreeFamⁱ	TF350737

Enzyme and pathway databases

Reactomeⁱ	R-MMU-383280 Nuclear Receptor transcription pathway

Reactomeⁱ

R-MMU-383280 Nuclear Receptor transcription pathway

Miscellaneous databases

ChiTaRSⁱ	Nr6a1 mouse
Protein Ontology More...PROⁱ	PR:Q64249
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000063972 Expressed in 212 organ(s), highest expression level in primitive streak
CleanExⁱ	MM_NR6A1
ExpressionAtlasⁱ	Q64249 baseline and differential
Genevisibleⁱ	Q64249 MM

Family and domain databases

Gene3Dⁱ	3.30.50.10, 1 hit
InterProⁱ	View protein in InterPro IPR035500 NHR_like_dom_sf IPR000536 Nucl_hrmn_rcpt_lig-bd IPR001723 Nuclear_hrmn_rcpt IPR001628 Znf_hrmn_rcpt IPR013088 Znf_NHR/GATA
Pfamⁱ	View protein in Pfam PF00104 Hormone_recep, 1 hit PF00105 zf-C4, 1 hit
PRINTSⁱ	PR00398 STRDHORMONER PR00047 STROIDFINGER
SMARTⁱ	View protein in SMART SM00430 HOLI, 1 hit SM00399 ZnF_C4, 1 hit
SUPFAMⁱ	SSF48508 SSF48508, 1 hit
PROSITEⁱ	View protein in PROSITE PS51843 NR_LBD, 1 hit PS00031 NUCLEAR_REC_DBD_1, 1 hit PS51030 NUCLEAR_REC_DBD_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	NR6A1_MOUSE
Accessionⁱ	Q64249Primary (citable) accession number: Q64249 Secondary accession number(s): A2AQL8, A2AQM1, Q687Z3
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
	Last sequence update:	November 1, 1996
	Last modified:	November 7, 2018
	This is version 160 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

3D-structure, Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
PDB cross-references
Index of Protein Data Bank (PDB) cross-references

UniProtKB

UniParc

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UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q64249 (NR6A1_MOUSE)

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Nuclear receptor subfamily 6 group A member 1

Nr6a1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Nucleus

Other locations

Keywords - Cellular componenti

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Alternative sequence

Sequence databases

Genome annotation databases

Keywords - Coding sequence diversityi

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Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Enzyme and pathway databases

Miscellaneous databases

Gene expression databases

Family and domain databases

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<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

Pathology & Biotechⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Keywords - Coding sequence diversityⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ