UniProtKB - Q641G3 (CCAR1_XENLA)
Protein
Cell division cycle and apoptosis regulator protein 1
Gene
ccar1
Organism
Xenopus laevis (African clawed frog)
Status
Functioni
Transcriptional coactivator for nuclear receptors which may play an important role in regulating cell growth and apoptosis.By similarity
GO - Biological processi
- cell cycle Source: UniProtKB-KW
- regulation of transcription, DNA-templated Source: InterPro
- regulation of translation Source: UniProtKB-KW
Keywordsi
Molecular function | Activator |
Biological process | Cell cycle, Translation regulation |
Names & Taxonomyi
Protein namesi | Recommended name: Cell division cycle and apoptosis regulator protein 1 |
Gene namesi | Name:ccar1 |
Organismi | Xenopus laevis (African clawed frog) |
Taxonomic identifieri | 8355 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Amphibia › Batrachia › Anura › Pipoidea › Pipidae › Xenopodinae › Xenopus › Xenopus |
Organism-specific databases
Xenbasei | XB-GENE-989032, ccar1.L |
Subcellular locationi
Other locations
- perinuclear region By similarity
Other locations
- perinuclear region of cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000233150 | 1 – 1157 | Cell division cycle and apoptosis regulator protein 1Add BLAST | 1157 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 1157 | PhosphoserineBy similarity | 1 |
Keywords - PTMi
PhosphoproteinProteomic databases
MaxQBi | Q641G3 |
PRIDEi | Q641G3 |
Interactioni
Protein-protein interaction databases
BioGRIDi | 607867, 1 interactor |
IntActi | Q641G3, 1 interactor |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 643 – 677 | SAPPROSITE-ProRule annotationAdd BLAST | 35 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 601 – 625 | Sequence analysisAdd BLAST | 25 | |
Coiled coili | 1043 – 1128 | Sequence analysisAdd BLAST | 86 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 48 – 84 | Ala-richAdd BLAST | 37 | |
Compositional biasi | 300 – 368 | Arg-richAdd BLAST | 69 | |
Compositional biasi | 680 – 725 | Glu-richAdd BLAST | 46 | |
Compositional biasi | 824 – 908 | Asp-richAdd BLAST | 85 |
Keywords - Domaini
Coiled coilPhylogenomic databases
OrthoDBi | 614048at2759 |
Family and domain databases
Gene3Di | 1.10.720.30, 1 hit |
InterProi | View protein in InterPro IPR025224, CCAR1/CCAR2 IPR025954, DBC1/CARP1_inactive_NUDIX_dom IPR011992, EF-hand-dom_pair IPR025223, S1-like_RNA-bd_dom IPR003034, SAP_dom IPR036361, SAP_dom_sf |
PANTHERi | PTHR14304, PTHR14304, 1 hit |
Pfami | View protein in Pfam PF14443, DBC1, 1 hit PF14444, S1-like, 1 hit PF02037, SAP, 1 hit |
SMARTi | View protein in SMART SM01122, DBC1, 1 hit SM00513, SAP, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit SSF68906, SSF68906, 1 hit |
PROSITEi | View protein in PROSITE PS50800, SAP, 1 hit |
i Sequence
Sequence statusi: Complete.
Q641G3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAQFGGQKNP PPWATQFTAT AVSQPGPLAV QQSSLLGASP TIYTQQSALA
60 70 80 90 100
AAGLASPSPA NYQLSQTAAL QQQAAAAAAA AAAALQQQYT QPQQTIYSVQ
110 120 130 140 150
QQLQPPPQAI LTQPAVALPT SLALSTPQQA AQITVSYPTP RSNQQQTQPQ
160 170 180 190 200
KQRVFTGVVT KLHETFGFVD EDVFFQLTAV KGKSPQAGDR VLVEATYNPN
210 220 230 240 250
MPFKWNAQRI QTLPNQNPAS AQSLIKNPAA VMQPVAQPTA YAVQTQPPPQ
260 270 280 290 300
AQTLLQAQIS AATLTPLLQT QTSPLLQQPQ QKAGLLQTPV RIVSQPQPVR
310 320 330 340 350
RIEPPSRFSV RNDRGDSILS RKDDRNRERE RERRRSRDRS PQRKRSRERS
360 370 380 390 400
PRRERERSPR RPRRVVPRYT VQISKFCLDC PGCDTMELRR RYQNLYIPSD
410 420 430 440 450
FFDAQFTWVD AFPISRPFQL GNYSNFYIMH KEVDPLEKNT AIVDPPDADH
460 470 480 490 500
TYSAKVMLLA SPSLEELYHK SCALAEDPIE VREGFQHPAR LIKFLVGMKG
510 520 530 540 550
KDEAMAIGGH WSPSLDGPNP DKDPSVLIRT AVRCCKALTG IELSLCTQWY
560 570 580 590 600
RFAEIRYHRP EETHKGRTVP AHVETVVLFF PDVWHCLPTR SEWENLCHGY
610 620 630 640 650
KQQLVDKLQG DRKEADGEQE EEDKEDGDAK EISTPTHWSK LDPKIMKVND
660 670 680 690 700
LRKELESRTL SSKGLKSQLI ARLTKQLRIE EQKEEQKELE KCEKEEEEEE
710 720 730 740 750
ERKSEDDKEE EERKRQEELE RQRREKRYML PDEPAIIVHP NWSAKNGKFD
760 770 780 790 800
CSIMSLSVLL DYRIEDNKEH SFEVSLFAEL FNEMLQRDFG VRIYRELLAL
810 820 830 840 850
PEKEEKKDKE KKCKKEDKRE RKEDKDDDDE PKPKRRKSSD DKIKLEEKEE
860 870 880 890 900
RKRDDRRKED YREEDDPDYE NQDDYEPIAA EEDDGDYDDR EDDDDDSSSK
910 920 930 940 950
DKREDKRDGN RYSKERQSKD KEKDKKQMVT VNRDLLMAFV YFDQSHCGYL
960 970 980 990 1000
LEKDLEEILY TLGLHLSRAQ VKKLFTKILL KESLLYRKLT DTATEDGSHE
1010 1020 1030 1040 1050
ETDPLHNDIL GNCSLLPSKA VRTGLSTVED KGGLIVYKGA MVDVGSLLQK
1060 1070 1080 1090 1100
LEKSEKTRTE LEHRLQTLES KTEEDEKTIS QLEASNRNLS EELKQTKDDV
1110 1120 1130 1140 1150
GHLKDSLKAA EDTRSLYEDQ LTNTIKNLSA AMGEIQVVLN KNPSTTEDQK
SKENGSS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC082374 mRNA Translation: AAH82374.1 |
RefSeqi | NP_001090254.1, NM_001096785.1 |
Genome annotation databases
GeneIDi | 779160 |
KEGGi | xla:779160 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC082374 mRNA Translation: AAH82374.1 |
RefSeqi | NP_001090254.1, NM_001096785.1 |
3D structure databases
SMRi | Q641G3 |
ModBasei | Search... |
Protein-protein interaction databases
BioGRIDi | 607867, 1 interactor |
IntActi | Q641G3, 1 interactor |
Proteomic databases
MaxQBi | Q641G3 |
PRIDEi | Q641G3 |
Genome annotation databases
GeneIDi | 779160 |
KEGGi | xla:779160 |
Organism-specific databases
CTDi | 779160 |
Xenbasei | XB-GENE-989032, ccar1.L |
Phylogenomic databases
OrthoDBi | 614048at2759 |
Family and domain databases
Gene3Di | 1.10.720.30, 1 hit |
InterProi | View protein in InterPro IPR025224, CCAR1/CCAR2 IPR025954, DBC1/CARP1_inactive_NUDIX_dom IPR011992, EF-hand-dom_pair IPR025223, S1-like_RNA-bd_dom IPR003034, SAP_dom IPR036361, SAP_dom_sf |
PANTHERi | PTHR14304, PTHR14304, 1 hit |
Pfami | View protein in Pfam PF14443, DBC1, 1 hit PF14444, S1-like, 1 hit PF02037, SAP, 1 hit |
SMARTi | View protein in SMART SM01122, DBC1, 1 hit SM00513, SAP, 1 hit |
SUPFAMi | SSF47473, SSF47473, 1 hit SSF68906, SSF68906, 1 hit |
PROSITEi | View protein in PROSITE PS50800, SAP, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | CCAR1_XENLA | |
Accessioni | Q641G3Primary (citable) accession number: Q641G3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 2, 2006 |
Last sequence update: | October 25, 2004 | |
Last modified: | August 12, 2020 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |