UniProtKB - Q63Y06 (SYR_BURPS)
Protein
Arginine--tRNA ligase
Gene
argS
Organism
Burkholderia pseudomallei (strain K96243)
Status
Functioni
Catalytic activityi
- EC:6.1.1.19UniRule annotation
GO - Molecular functioni
- arginine-tRNA ligase activity Source: UniProtKB-UniRule
- ATP binding Source: UniProtKB-UniRule
GO - Biological processi
- arginyl-tRNA aminoacylation Source: UniProtKB-UniRule
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | BPSE272560:G1G3Q-393-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)Alternative name(s): Arginyl-tRNA synthetaseUniRule annotation Short name: ArgRSUniRule annotation |
Gene namesi | Name:argSUniRule annotation Ordered Locus Names:BPSL0383 |
Organismi | Burkholderia pseudomallei (strain K96243) |
Taxonomic identifieri | 272560 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000241997 | 1 – 594 | Arginine--tRNA ligaseAdd BLAST | 594 |
Interactioni
Subunit structurei
Monomer.
UniRule annotationProtein-protein interaction databases
STRINGi | 272560.BPSL0383 |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 139 – 149 | 'HIGH' regionAdd BLAST | 11 |
Sequence similaritiesi
Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation
Phylogenomic databases
eggNOGi | COG0018, Bacteria |
OMAi | NKPLHLG |
Family and domain databases
CDDi | cd00671, ArgRS_core, 1 hit |
Gene3Di | 3.30.1360.70, 1 hit 3.40.50.620, 1 hit |
HAMAPi | MF_00123, Arg_tRNA_synth, 1 hit |
InterProi | View protein in InterPro IPR001412, aa-tRNA-synth_I_CS IPR001278, Arg-tRNA-ligase IPR005148, Arg-tRNA-synth_N IPR036695, Arg-tRNA-synth_N_sf IPR035684, ArgRS_core IPR008909, DALR_anticod-bd IPR014729, Rossmann-like_a/b/a_fold IPR009080, tRNAsynth_Ia_anticodon-bd |
PANTHERi | PTHR11956, PTHR11956, 1 hit |
Pfami | View protein in Pfam PF03485, Arg_tRNA_synt_N, 1 hit PF05746, DALR_1, 1 hit PF00750, tRNA-synt_1d, 1 hit |
PRINTSi | PR01038, TRNASYNTHARG |
SMARTi | View protein in SMART SM01016, Arg_tRNA_synt_N, 1 hit SM00836, DALR_1, 1 hit |
SUPFAMi | SSF47323, SSF47323, 1 hit SSF55190, SSF55190, 1 hit |
TIGRFAMsi | TIGR00456, argS, 1 hit |
PROSITEi | View protein in PROSITE PS00178, AA_TRNA_LIGASE_I, 1 hit |
i Sequence
Sequence statusi: Complete.
Q63Y06-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLPAQKHTLE TLLENSVKQV VQASKGDADA AFVLPAIALE RPKVAAHGDV
60 70 80 90 100
ACNVALQLAK PLGANPRQLA EQIVAALTAQ PEAAGLVDAA EIAGPGFINL
110 120 130 140 150
RLTPASKQAV IGAVLAQGRA FGASERDHGK RVLLEFVSAN PTGPLHVGHG
160 170 180 190 200
RQAALGDALA NVLASQGYAV HREFYYNDAG VQIGNLAIST QARARGLKPG
210 220 230 240 250
DAGWPEAAYN GEYIADIARD YLNGETVAAS DGEPVTGKRD VEDLEAIRKF
260 270 280 290 300
AVTYLRREQD MDLKAFGVKF DQYYLESSLY TEGRVEKTVD ALIAAGMTYE
310 320 330 340 350
QEGALWLRTT DEGDDKDRVM RKTDGTYTYF VPDVAYHVTK WERGFTKVIN
360 370 380 390 400
IQGSDHHGTI ARVRAGLQGL HIGIPKGYPD YVLHKMVTVM RDGQEVKISK
410 420 430 440 450
RAGSYVTVRD LIEWSGGATP GSEGSPELLD EATITRGRDA VRFFLISRKA
460 470 480 490 500
DTEFVFDIDL ALKQNDENPV YYVQYAHARI CSVINEWKSR YGATDALLPG
510 520 530 540 550
ADLSPLDSKQ AMALMQKLAE YPDVLAHAAG ELAPHAVAFY LRELASEFHS
560 570 580 590
FYNAERVLVD EQAPRTARVA LLAATRQVLE NGLAMLGVSA PSKM
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX571965 Genomic DNA Translation: CAH34371.1 |
RefSeqi | WP_004522947.1, NZ_CP009538.1 YP_107009.1, NC_006350.1 |
Genome annotation databases
EnsemblBacteriai | CAH34371; CAH34371; BPSL0383 |
GeneIDi | 45704266 |
KEGGi | bps:BPSL0383 |
PATRICi | fig|272560.51.peg.1284 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX571965 Genomic DNA Translation: CAH34371.1 |
RefSeqi | WP_004522947.1, NZ_CP009538.1 YP_107009.1, NC_006350.1 |
3D structure databases
SMRi | Q63Y06 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 272560.BPSL0383 |
Genome annotation databases
EnsemblBacteriai | CAH34371; CAH34371; BPSL0383 |
GeneIDi | 45704266 |
KEGGi | bps:BPSL0383 |
PATRICi | fig|272560.51.peg.1284 |
Phylogenomic databases
eggNOGi | COG0018, Bacteria |
OMAi | NKPLHLG |
Enzyme and pathway databases
BioCyci | BPSE272560:G1G3Q-393-MONOMER |
Family and domain databases
CDDi | cd00671, ArgRS_core, 1 hit |
Gene3Di | 3.30.1360.70, 1 hit 3.40.50.620, 1 hit |
HAMAPi | MF_00123, Arg_tRNA_synth, 1 hit |
InterProi | View protein in InterPro IPR001412, aa-tRNA-synth_I_CS IPR001278, Arg-tRNA-ligase IPR005148, Arg-tRNA-synth_N IPR036695, Arg-tRNA-synth_N_sf IPR035684, ArgRS_core IPR008909, DALR_anticod-bd IPR014729, Rossmann-like_a/b/a_fold IPR009080, tRNAsynth_Ia_anticodon-bd |
PANTHERi | PTHR11956, PTHR11956, 1 hit |
Pfami | View protein in Pfam PF03485, Arg_tRNA_synt_N, 1 hit PF05746, DALR_1, 1 hit PF00750, tRNA-synt_1d, 1 hit |
PRINTSi | PR01038, TRNASYNTHARG |
SMARTi | View protein in SMART SM01016, Arg_tRNA_synt_N, 1 hit SM00836, DALR_1, 1 hit |
SUPFAMi | SSF47323, SSF47323, 1 hit SSF55190, SSF55190, 1 hit |
TIGRFAMsi | TIGR00456, argS, 1 hit |
PROSITEi | View protein in PROSITE PS00178, AA_TRNA_LIGASE_I, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SYR_BURPS | |
Accessioni | Q63Y06Primary (citable) accession number: Q63Y06 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 27, 2006 |
Last sequence update: | October 25, 2004 | |
Last modified: | December 2, 2020 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - Aminoacyl-tRNA synthetases
List of aminoacyl-tRNA synthetase entries