UniProtKB - Q63S19 (METN1_BURPS)
Protein
Methionine import ATP-binding protein MetN 1
Gene
metN1
Organism
Burkholderia pseudomallei (strain K96243)
Status
Functioni
Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system.UniRule annotation
Catalytic activityi
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 38 – 45 | ATPUniRule annotation | 8 |
GO - Molecular functioni
- ATPase activity Source: InterPro
- ATPase-coupled amino acid transmembrane transporter activity Source: UniProtKB-UniRule
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- methionine transport Source: InterPro
Keywordsi
Molecular function | Translocase |
Biological process | Amino-acid transport, Transport |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | BPSE272560:G1G3Q-2618-MONOMER |
Names & Taxonomyi
Protein namesi | Recommended name: Methionine import ATP-binding protein MetN 1UniRule annotation (EC:7.4.2.11UniRule annotation) |
Gene namesi | Name:metN1UniRule annotation Ordered Locus Names:BPSL2503 |
Organismi | Burkholderia pseudomallei (strain K96243) |
Taxonomic identifieri | 272560 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › pseudomallei group › |
Proteomesi |
|
Subcellular locationi
- Cell inner membrane UniRule annotation; Peripheral membrane protein UniRule annotation
GO - Cellular componenti
- plasma membrane Source: UniProtKB-SubCell
Keywords - Cellular componenti
Cell inner membrane, Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000270265 | 1 – 344 | Methionine import ATP-binding protein MetN 1Add BLAST | 344 |
Interactioni
Subunit structurei
The complex is composed of two ATP-binding proteins (MetN), two transmembrane proteins (MetI) and a solute-binding protein (MetQ).
UniRule annotationProtein-protein interaction databases
STRINGi | 272560.BPSL2503 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 2 – 241 | ABC transporterUniRule annotationAdd BLAST | 240 |
Sequence similaritiesi
Belongs to the ABC transporter superfamily. Methionine importer (TC 3.A.1.24) family. [View classification]UniRule annotation
Phylogenomic databases
eggNOGi | COG1135, Bacteria |
OMAi | LIRLINC |
Family and domain databases
CDDi | cd03258, ABC_MetN_methionine_transporter, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR026253, ABC_MetN IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR017908, ABC_transprt_methionine_MetN_C IPR041701, MetN_ABC IPR018449, NIL_domain IPR027417, P-loop_NTPase |
PANTHERi | PTHR43166:SF5, PTHR43166:SF5, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF09383, NIL, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM00930, NIL, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS51264, METN, 1 hit |
i Sequence
Sequence statusi: Complete.
Q63S19-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MIEIRNLSQR FEGPRGWIEA LHNVNLTIPQ GEVFGIIGRS GAGKSTLVRT
60 70 80 90 100
INLLTRPSEG SVFVGGRDLT QLSAAELRGA RRDIGMIFQH FNLLSSRTVF
110 120 130 140 150
DNVALPLELA GVKRAQIEAT VLPLLDLVGL AAQKDRYPAQ ISGGQKQRVG
160 170 180 190 200
IARALASKPK VLLSDEATSA LDPETTRAIL DLLRRINREL GLTIVLITHQ
210 220 230 240 250
MEVIKDVCDR VAVLDAGRVV EEGNVIDVFM RPHHEVTRAL IGDVIAQELP
260 270 280 290 300
PAMKARVAER LKTGSGHLLR LAFTGSGVDQ PILSETIRRY ELDFNILHGQ
310 320 330 340
IDEIQGRAFG SLAVLATGEP GKVGQAFAYL REQGVVVEEL SYVE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX571965 Genomic DNA Translation: CAH36509.1 |
RefSeqi | WP_004190044.1, NZ_CP009538.1 YP_109098.1, NC_006350.1 |
Genome annotation databases
EnsemblBacteriai | CAH36509; CAH36509; BPSL2503 |
GeneIDi | 45702902 |
KEGGi | bps:BPSL2503 |
PATRICi | fig|272560.51.peg.2879 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX571965 Genomic DNA Translation: CAH36509.1 |
RefSeqi | WP_004190044.1, NZ_CP009538.1 YP_109098.1, NC_006350.1 |
3D structure databases
SMRi | Q63S19 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 272560.BPSL2503 |
Genome annotation databases
EnsemblBacteriai | CAH36509; CAH36509; BPSL2503 |
GeneIDi | 45702902 |
KEGGi | bps:BPSL2503 |
PATRICi | fig|272560.51.peg.2879 |
Phylogenomic databases
eggNOGi | COG1135, Bacteria |
OMAi | LIRLINC |
Enzyme and pathway databases
BioCyci | BPSE272560:G1G3Q-2618-MONOMER |
Family and domain databases
CDDi | cd03258, ABC_MetN_methionine_transporter, 1 hit |
InterProi | View protein in InterPro IPR003593, AAA+_ATPase IPR026253, ABC_MetN IPR003439, ABC_transporter-like IPR017871, ABC_transporter_CS IPR017908, ABC_transprt_methionine_MetN_C IPR041701, MetN_ABC IPR018449, NIL_domain IPR027417, P-loop_NTPase |
PANTHERi | PTHR43166:SF5, PTHR43166:SF5, 1 hit |
Pfami | View protein in Pfam PF00005, ABC_tran, 1 hit PF09383, NIL, 1 hit |
SMARTi | View protein in SMART SM00382, AAA, 1 hit SM00930, NIL, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
PROSITEi | View protein in PROSITE PS00211, ABC_TRANSPORTER_1, 1 hit PS50893, ABC_TRANSPORTER_2, 1 hit PS51264, METN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | METN1_BURPS | |
Accessioni | Q63S19Primary (citable) accession number: Q63S19 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | January 9, 2007 |
Last sequence update: | October 25, 2004 | |
Last modified: | December 2, 2020 | |
This is version 116 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families