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Protein

Ribose 1,5-bisphosphate phosphokinase PhnN

Gene

phnN

Organism
Burkholderia pseudomallei (strain K96243)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP).UniRule annotation

Catalytic activityi

ATP + alpha-D-ribose 1,5-bisphosphate = ADP + 5-phospho-alpha-D-ribose 1-diphosphate.UniRule annotation

Pathwayi: 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis

This protein is involved in step 3 of the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II).UniRule annotation
Proteins known to be involved in the 3 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. no protein annotated in this organism
  3. Ribose 1,5-bisphosphate phosphokinase PhnN (phnN)
This subpathway is part of the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis, which is itself part of Metabolic intermediate biosynthesis.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes 5-phospho-alpha-D-ribose 1-diphosphate from D-ribose 5-phosphate (route II), the pathway 5-phospho-alpha-D-ribose 1-diphosphate biosynthesis and in Metabolic intermediate biosynthesis.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi11 – 18ATPUniRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferase
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBPSE272560:G1G3Q-2993-MONOMER
UniPathwayiUPA00087; UER00175

Names & Taxonomyi

Protein namesi
Recommended name:
Ribose 1,5-bisphosphate phosphokinase PhnNUniRule annotation (EC:2.7.4.23UniRule annotation)
Alternative name(s):
Ribose 1,5-bisphosphokinaseUniRule annotation
Gene namesi
Name:phnNUniRule annotation
Ordered Locus Names:BPSL2860
OrganismiBurkholderia pseudomallei (strain K96243)
Taxonomic identifieri272560 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiapseudomallei group
Proteomesi
  • UP000000605 Componenti: Chromosome 1

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00004127771 – 184Ribose 1,5-bisphosphate phosphokinase PhnNAdd BLAST184

Interactioni

Protein-protein interaction databases

STRINGi272560.BPSL2860

Structurei

3D structure databases

ProteinModelPortaliQ63R14
SMRiQ63R14
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribose 1,5-bisphosphokinase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105MFQ Bacteria
COG3709 LUCA
HOGENOMiHOG000037637
KOiK05774
OMAiMARLIWL

Family and domain databases

HAMAPiMF_00836 PhnN, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR027417 P-loop_NTPase
IPR012699 PhnN
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR02322 phosphon_PhnN, 1 hit

Sequencei

Sequence statusi: Complete.

Q63R14-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAERLVYVM GPSGAGKDSL LAYARKHVRE PRIAFAHRYI TRKSDGHENH
60 70 80 90 100
VELTRDEFAA RAQLGFFALE WSSHGFRYGV GVEIDAWLAA GSVVVVSGSR
110 120 130 140 150
AHLPAALERY PQMCVVHIDA APHVLAERLA TRGRETADEI RARLARSVRW
160 170 180
AVPDGVALTA IDNSGTLDDA GRVLVALLEG LARS
Length:184
Mass (Da):20,067
Last modified:October 25, 2004 - v1
Checksum:i4805DA45BC68C7C1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX571965 Genomic DNA Translation: CAH36870.1
RefSeqiWP_004527702.1, NZ_CP009538.1
YP_109454.1, NC_006350.1

Genome annotation databases

EnsemblBacteriaiCAH36870; CAH36870; BPSL2860
GeneIDi3094078
KEGGibps:BPSL2860
PATRICifig|272560.51.peg.2440

Similar proteinsi

Entry informationi

Entry nameiPHNN_BURPS
AccessioniPrimary (citable) accession number: Q63R14
Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 21, 2011
Last sequence update: October 25, 2004
Last modified: February 28, 2018
This is version 72 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families
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