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Entry version 176 (02 Jun 2021)
Sequence version 2 (27 May 2002)
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Protein

Nuclear pore glycoprotein p62

Gene

Nup62

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Essential component of the nuclear pore complex. The N-terminal is probably involved in nucleocytoplasmic transport. The C-terminal is involved in protein-protein interaction probably via coiled-coil formation, promotes its association with centrosomes and may function in anchorage of p62 to the pore complex. Plays a role in mitotic cell cycle progression by regulating centrosome segregation, centriole maturation and spindle orientation. It might be involved in protein recruitment to the centrosome after nuclear breakdown.

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA transport, Protein transport, Translocation, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-159227, Transport of the SLBP independent Mature mRNA
R-MMU-159230, Transport of the SLBP Dependant Mature mRNA
R-MMU-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-MMU-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein
R-MMU-191859, snRNP Assembly
R-MMU-3108214, SUMOylation of DNA damage response and repair proteins
R-MMU-3232142, SUMOylation of ubiquitinylation proteins
R-MMU-3301854, Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453, Regulation of HSF1-mediated heat shock response
R-MMU-4085377, SUMOylation of SUMOylation proteins
R-MMU-4551638, SUMOylation of chromatin organization proteins
R-MMU-4570464, SUMOylation of RNA binding proteins
R-MMU-4615885, SUMOylation of DNA replication proteins
R-MMU-5578749, Transcriptional regulation by small RNAs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nuclear pore glycoprotein p62
Alternative name(s):
62 kDa nucleoporin
Nucleoporin Nup62
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Nup62
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1351500, Nup62

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Nuclear pore complex, Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology%5Fand%5Fbiotech%5Fsection">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi479C → S: Loss of reduction of influx rate of NLS cargo upon oxidative stress; when associated with S-509. 1 Publication1
Mutagenesisi510C → S: Loss of reduction of influx rate of NLS cargo upon oxidative stress; when associated with S-478. 1 Publication1

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section indicates that the initiator methionine is cleaved from the mature protein.<p><a href='/help/init_met' target='_top'>More...</a></p>Initiator methionineiRemovedBy similarity
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002048812 – 526Nuclear pore glycoprotein p62Add BLAST525

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei2N-acetylserineBy similarity1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi377O-linked (GlcNAc) threonineBy similarity1
Modified residuei412PhosphoserineCombined sources1
Modified residuei422PhosphoserineBy similarity1
Glycosylationi472O-linked (GlcNAc) serineBy similarity1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi479Interchain (with NUP155)1 Publication
Disulfide bondi510Interchain (with NUP155)1 Publication

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

O-glycosylated.1 Publication
The inner channel of the NPC has a different redox environment from the cytoplasm and allows the formation of interchain disulfide bonds between some nucleoporins, the significant increase of these linkages upon oxidative stress reduces the permeability of the NPC.

Keywords - PTMi

Acetylation, Disulfide bond, Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q63850

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q63850

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q63850

PRoteomics IDEntifications database

More...
PRIDEi
Q63850

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
293814

PTM databases

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q63850, 2 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q63850

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q63850

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q63850

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000109511, Expressed in floor plate of midbrain and 312 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q63850, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the p62 complex, a complex at least composed of NUP62, NUP54, and NUP58.

Interacts with NUP88.

Interacts with NUTF2.

Interacts with HIKESHI.

Interacts with OSBPL8.

Interacts with CAPG.

Interacts with SAS6 and TUBG1 at the centrosome.

Interacts with MCM3AP (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
201879, 13 interactors

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-4474, Nuclear pore complex

Protein interaction database and analysis system

More...
IntActi
Q63850, 2 interactors

Molecular INTeraction database

More...
MINTi
Q63850

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000056785

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q63850, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q63850

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati6 – 71By similarity2
Repeati46 – 472By similarity2
Repeati78 – 793By similarity2
Repeati115 – 1164By similarity2
Repeati143 – 1445By similarity2

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni6 – 1445 X 2 AA repeats of F-GBy similarityAdd BLAST139
Regioni43 – 82DisorderedSequence analysisAdd BLAST40
Regioni128 – 148DisorderedSequence analysisAdd BLAST21
Regioni332 – 462Required for centrosome localizationBy similarityAdd BLAST131

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili332 – 462Sequence analysisAdd BLAST131

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Contains FG repeats.

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the nucleoporin NSP1/NUP62 family.Curated

Keywords - Domaini

Coiled coil, Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG2196, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000161737

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_025936_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q63850

Identification of Orthologs from Complete Genome Data

More...
OMAi
EMMSKQV

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q63850

TreeFam database of animal gene trees

More...
TreeFami
TF324795

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026010, NSP1/NUP62
IPR007758, Nucleoporin_NSP1_C
IPR033072, NUP62_met

The PANTHER Classification System

More...
PANTHERi
PTHR12084, PTHR12084, 1 hit
PTHR12084:SF12, PTHR12084:SF12, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05064, Nsp1_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q63850-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGFNFGGTG APAGGFTFGT AKTATTTPAT GFSFSASGTG TGGFNFGTPS
60 70 80 90 100
QPAATTPSTS LFSLTTQTPT TQTPGFNFGT TPASGGTGFS LGISTPKLSL
110 120 130 140 150
SNAAATPATA NTGSFGLGSS TLTNAISSGS TSNQGTAPTG FVFGSSTTSA
160 170 180 190 200
PSTGSTGFSF TSGSASQPGA SGFSLGSVGS SAQPTALSGS PFTPATLVTT
210 220 230 240 250
TAGATQPAAA APTAATTSAG STLFASIAAA PASSSATGLS LPAPVTTAAT
260 270 280 290 300
PSAGTLGFSL KAPGAAPGAS TTSTTTTTTT TTTTAAAAAA STTTTGFALS
310 320 330 340 350
LKPLVSAGPS SVAATALPAS STAAGTATGP AMTYAQLESL INKWSLELED
360 370 380 390 400
QERHFLQQAT QVNAWDRTLI ENGEKITSLH REVEKVKLDQ KRLDQELDFI
410 420 430 440 450
LSQQKELEDL LSPLEESVKE QSGTIYLQHA DEEREKTYKL AENIDAQLKR
460 470 480 490 500
MAQDLKDIIE HLNMAGGPAD TSDPLQQICK ILNAHMDSLQ WVDQSSALLQ
510 520
RRVEEASRVC EGRRKEQERS LRIAFD
Length:526
Mass (Da):53,255
Last modified:May 27, 2002 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i54AE74B211018FE4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A140LJH5A0A140LJH5_MOUSE
Nuclear pore glycoprotein p62
Nup62
42Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A140LJ77A0A140LJ77_MOUSE
Nuclear pore glycoprotein p62
Nup62
159Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti113G → V in AAB19953 (PubMed:1915419).Curated1
Sequence conflicti319A → V in AAB19953 (PubMed:1915419).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
S59342 mRNA Translation: AAB19953.1
BC005784 mRNA Translation: AAH05784.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS21216.1

Protein sequence database of the Protein Information Resource

More...
PIRi
A56573

NCBI Reference Sequences

More...
RefSeqi
NP_444304.1, NM_053074.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000057195; ENSMUSP00000056785; ENSMUSG00000109511
ENSMUST00000207103; ENSMUSP00000147181; ENSMUSG00000109511
ENSMUST00000208626; ENSMUSP00000146695; ENSMUSG00000109511

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
18226

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:18226

UCSC genome browser

More...
UCSCi
uc009gqw.2, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
S59342 mRNA Translation: AAB19953.1
BC005784 mRNA Translation: AAH05784.1
CCDSiCCDS21216.1
PIRiA56573
RefSeqiNP_444304.1, NM_053074.2

3D structure databases

SMRiQ63850
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi201879, 13 interactors
ComplexPortaliCPX-4474, Nuclear pore complex
IntActiQ63850, 2 interactors
MINTiQ63850
STRINGi10090.ENSMUSP00000056785

PTM databases

GlyGeniQ63850, 2 sites
iPTMnetiQ63850
PhosphoSitePlusiQ63850
SwissPalmiQ63850

Proteomic databases

EPDiQ63850
MaxQBiQ63850
PaxDbiQ63850
PRIDEiQ63850
ProteomicsDBi293814

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
1686, 360 antibodies

The DNASU plasmid repository

More...
DNASUi
18226

Genome annotation databases

EnsembliENSMUST00000057195; ENSMUSP00000056785; ENSMUSG00000109511
ENSMUST00000207103; ENSMUSP00000147181; ENSMUSG00000109511
ENSMUST00000208626; ENSMUSP00000146695; ENSMUSG00000109511
GeneIDi18226
KEGGimmu:18226
UCSCiuc009gqw.2, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23636
MGIiMGI:1351500, Nup62

Phylogenomic databases

eggNOGiKOG2196, Eukaryota
GeneTreeiENSGT00940000161737
HOGENOMiCLU_025936_0_0_1
InParanoidiQ63850
OMAiEMMSKQV
PhylomeDBiQ63850
TreeFamiTF324795

Enzyme and pathway databases

ReactomeiR-MMU-159227, Transport of the SLBP independent Mature mRNA
R-MMU-159230, Transport of the SLBP Dependant Mature mRNA
R-MMU-159231, Transport of Mature mRNA Derived from an Intronless Transcript
R-MMU-159236, Transport of Mature mRNA derived from an Intron-Containing Transcript
R-MMU-170822, Regulation of Glucokinase by Glucokinase Regulatory Protein
R-MMU-191859, snRNP Assembly
R-MMU-3108214, SUMOylation of DNA damage response and repair proteins
R-MMU-3232142, SUMOylation of ubiquitinylation proteins
R-MMU-3301854, Nuclear Pore Complex (NPC) Disassembly
R-MMU-3371453, Regulation of HSF1-mediated heat shock response
R-MMU-4085377, SUMOylation of SUMOylation proteins
R-MMU-4551638, SUMOylation of chromatin organization proteins
R-MMU-4570464, SUMOylation of RNA binding proteins
R-MMU-4615885, SUMOylation of DNA replication proteins
R-MMU-5578749, Transcriptional regulation by small RNAs

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
18226, 15 hits in 51 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Nup62, mouse

Protein Ontology

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PROi
PR:Q63850
RNActiQ63850, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000109511, Expressed in floor plate of midbrain and 312 other tissues
GenevisibleiQ63850, MM

Family and domain databases

InterProiView protein in InterPro
IPR026010, NSP1/NUP62
IPR007758, Nucleoporin_NSP1_C
IPR033072, NUP62_met
PANTHERiPTHR12084, PTHR12084, 1 hit
PTHR12084:SF12, PTHR12084:SF12, 1 hit
PfamiView protein in Pfam
PF05064, Nsp1_C, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNUP62_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q63850
Secondary accession number(s): Q99JN7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: May 27, 2002
Last modified: June 2, 2021
This is version 176 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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