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UniProtKB - Q63158 (Q63158_RAT)
Protein
Submitted name:
RCG21090
Gene
Sp4
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- DNA binding Source: RGD
- DNA-binding transcription factor activity Source: RGD
- DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO_Central
- identical protein binding Source: RGD
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: GO_Central
- sequence-specific DNA binding Source: RGD
GO - Biological processi
- regulation of heart contraction Source: RGD
- regulation of transcription by RNA polymerase II Source: RGD
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: RCG21090ImportedSubmitted name: Sp4 transcription factorImportedSubmitted name: Zinc finger proteinImported |
Gene namesi | ORF Names:rCG_21090Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 3741, Sp4 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000005472, Expressed in thymus and 19 other tissues |
Interactioni
GO - Molecular functioni
- identical protein binding Source: RGD
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000007625 |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 646 – 675 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 676 – 705 | C2H2-typeInterPro annotationAdd BLAST | 30 | |
Domaini | 706 – 733 | C2H2-typeInterPro annotationAdd BLAST | 28 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 66 | DisorderedSequence analysisAdd BLAST | 66 | |
Regioni | 107 – 148 | DisorderedSequence analysisAdd BLAST | 42 | |
Regioni | 274 – 386 | DisorderedSequence analysisAdd BLAST | 113 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 1 – 15 | Basic and acidic residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 30 – 48 | Polar residuesSequence analysisAdd BLAST | 19 |
Keywords - Domaini
Zinc-fingerPROSITE-ProRule annotationPhylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000157827 |
HOGENOMi | CLU_019688_2_0_1 |
OMAi | HINPQPA |
OrthoDBi | 1085860at2759 |
TreeFami | TF350150 |
Family and domain databases
InterProi | View protein in InterPro IPR030453, SP4 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR23235:SF17, PTHR23235:SF17, 2 hits |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
i Sequence
Sequence statusi: Complete.
Q63158-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSDQKKEEEE EAAAAMATEG GKTSEPENNN KKPKTSGSQD SQPSPLALLA
60 70 80 90 100
ATCSKIGTPG ENQATGQQQI IIDPSQGLVQ LQNQPQQLEL VTTQLAGNAW
110 120 130 140 150
QLVASTPPAS KENNVSQPAS SSSSSSSSNN GSSSPTKTKS GNPSTPNQFQ
160 170 180 190 200
VIQVQNPSGS VQYQVIPQLQ TVEGQQIQIN PTSSSSLQDL QGQIQLISAG
210 220 230 240 250
NNQAILTAAN RTASGNILAQ NLANQTVPVQ IRPGVSIPLQ LQTLPGTQAQ
260 270 280 290 300
VVTTLPINIG GVTLALPVIN NVTAGGGTGQ VGQPTTTTTD SGTSNGNQLV
310 320 330 340 350
STPTTSTAPA STMPESPSSS TTCTTTASTS LTSSDTLVSS ADTGQYASTS
360 370 380 390 400
ASSSERTIEE PQTPAATESE AQSSSQLQSN GIQNAQDQSN SLQQVQIVGQ
410 420 430 440 450
PILQQIQIQQ PQQQIIQAIP PQSFQLQSGQ TIQTIQQQPL QNVQLQAVNP
460 470 480 490 500
TQVLIRAPTL TPSGQISWQT VQVQNIQSLS NLQVQNAGLS QQLTITPVSS
510 520 530 540 550
SGGTTLAQIA PVAVAGAPIT LNTAQLASVP NLQTVSVANL GAAGVQVQGV
560 570 580 590 600
PVTITSVAGQ QQGQDGVKVQ QATIAPVTVA VGGIANATIG AVSPDQLTQV
610 620 630 640 650
HLQQGQQTSD AEVQPGKRLR RVACSCPNCR EGEGRGSSEP GKKKQHVCHI
660 670 680 690 700
EGCGKVYGKT SHLRAHLRWH TGERPFICNW MFCGKRFTRS DELQRHRRTH
710 720 730 740 750
TGEKRFECPE CSKRFMRSDH LSKHVKTHQN KKGGGTALAI VTSGELDSSV
760 770 780
TEVLGSPRIV TVAAISQDSN PATPNVSTNM EEF
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07065921 Genomic DNA No translation available. U07610 mRNA Translation: AAA17375.1 CH474038 Genomic DNA Translation: EDL89090.1 |
PIRi | A48143 |
RefSeqi | NP_036893.1, NM_012761.1 |
Genome annotation databases
Ensembli | ENSRNOT00000007625; ENSRNOP00000007625; ENSRNOG00000005472 |
GeneIDi | 25162 |
KEGGi | rno:25162 |
UCSCi | RGD:3741, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07065921 Genomic DNA No translation available. U07610 mRNA Translation: AAA17375.1 CH474038 Genomic DNA Translation: EDL89090.1 |
PIRi | A48143 |
RefSeqi | NP_036893.1, NM_012761.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000007625 |
Genome annotation databases
Ensembli | ENSRNOT00000007625; ENSRNOP00000007625; ENSRNOG00000005472 |
GeneIDi | 25162 |
KEGGi | rno:25162 |
UCSCi | RGD:3741, rat |
Organism-specific databases
CTDi | 6671 |
RGDi | 3741, Sp4 |
Phylogenomic databases
eggNOGi | KOG1721, Eukaryota |
GeneTreei | ENSGT00940000157827 |
HOGENOMi | CLU_019688_2_0_1 |
OMAi | HINPQPA |
OrthoDBi | 1085860at2759 |
TreeFami | TF350150 |
Gene expression databases
Bgeei | ENSRNOG00000005472, Expressed in thymus and 19 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR030453, SP4 IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
PANTHERi | PTHR23235:SF17, PTHR23235:SF17, 2 hits |
Pfami | View protein in Pfam PF00096, zf-C2H2, 2 hits |
SMARTi | View protein in SMART SM00355, ZnF_C2H2, 3 hits |
SUPFAMi | SSF57667, SSF57667, 2 hits |
PROSITEi | View protein in PROSITE PS00028, ZINC_FINGER_C2H2_1, 3 hits PS50157, ZINC_FINGER_C2H2_2, 3 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | Q63158_RAT | |
Accessioni | Q63158Primary (citable) accession number: Q63158 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1996 |
Last sequence update: | November 1, 1996 | |
Last modified: | January 19, 2022 | |
This is version 152 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |