Sp4

Functionⁱ

GO - Molecular functionⁱ

DNA binding
Source: RGD
Inferred from direct assayⁱ
- 15572681
DNA-binding transcription factor activity
Source: RGD
Inferred from direct assayⁱ
- 12746457
DNA-binding transcription factor activity, RNA polymerase II-specific
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635
sequence-specific DNA binding Source: Ensembl
transcription coactivator activity Source: InterPro

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of transcription by RNA polymerase II
Source: GO_Central
Inferred from biological aspect of ancestorⁱ
- 21873635

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Ligand	Metal-binding, Zinc

Ligand

Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: RCG21090Imported Submitted name: Sp4 transcription factorImported Submitted name: Zinc finger proteinImported
Gene namesⁱ	Name:Sp4Imported Synonyms:HF-1bImported ORF Names:rCG_21090Imported
Organismⁱ	Rattus norvegicus (Rat)Imported
Taxonomic identifierⁱ	10116 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus
Proteomesⁱ	UP000002494 Componentⁱ: Chromosome 6

Organism-specific databases

Rat genome database More...RGDⁱ	3741 Sp4

RGDⁱ

3741 Sp4

Subcellular locationⁱ

GO - Cellular component

PTM / Processingⁱ

Proteomic databases

PRIDEⁱ	Q63158

PRIDEⁱ

Q63158

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSRNOG00000005472 Expressed in 9 organ(s), highest expression level in spleen

Bgeeⁱ

ENSRNOG00000005472 Expressed in 9 organ(s), highest expression level in spleen

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000007625

STRINGⁱ

10116.ENSRNOP00000007625

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	646 – 675	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	676 – 705	C2H2-typeInterPro annotationAdd BLAST	30
Domainⁱ	706 – 733	C2H2-typeInterPro annotationAdd BLAST	28

Keywords - Domainⁱ

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00760000118984
HOGENOMⁱ	HOG000234295
HOVERGENⁱ	HBG008933
KEGG Orthology (KO) More...KOⁱ	K09194
OMAⁱ	CHMEGCG
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G0HX6
TreeFamⁱ	TF350150

Family and domain databases

InterProⁱ	View protein in InterPro IPR030453 SP4 IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR23235:SF17 PTHR23235:SF17, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits

Sequenceⁱ

Sequence statusⁱ: Complete.

Q63158-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MSDQKKEEEE EAAAAMATEG GKTSEPENNN KKPKTSGSQD SQPSPLALLA 
        60         70         80         90        100
ATCSKIGTPG ENQATGQQQI IIDPSQGLVQ LQNQPQQLEL VTTQLAGNAW 
       110        120        130        140        150
QLVASTPPAS KENNVSQPAS SSSSSSSSNN GSSSPTKTKS GNPSTPNQFQ 
       160        170        180        190        200
VIQVQNPSGS VQYQVIPQLQ TVEGQQIQIN PTSSSSLQDL QGQIQLISAG 
       210        220        230        240        250
NNQAILTAAN RTASGNILAQ NLANQTVPVQ IRPGVSIPLQ LQTLPGTQAQ 
       260        270        280        290        300
VVTTLPINIG GVTLALPVIN NVTAGGGTGQ VGQPTTTTTD SGTSNGNQLV 
       310        320        330        340        350
STPTTSTAPA STMPESPSSS TTCTTTASTS LTSSDTLVSS ADTGQYASTS 
       360        370        380        390        400
ASSSERTIEE PQTPAATESE AQSSSQLQSN GIQNAQDQSN SLQQVQIVGQ 
       410        420        430        440        450
PILQQIQIQQ PQQQIIQAIP PQSFQLQSGQ TIQTIQQQPL QNVQLQAVNP 
       460        470        480        490        500
TQVLIRAPTL TPSGQISWQT VQVQNIQSLS NLQVQNAGLS QQLTITPVSS 
       510        520        530        540        550
SGGTTLAQIA PVAVAGAPIT LNTAQLASVP NLQTVSVANL GAAGVQVQGV 
       560        570        580        590        600
PVTITSVAGQ QQGQDGVKVQ QATIAPVTVA VGGIANATIG AVSPDQLTQV 
       610        620        630        640        650
HLQQGQQTSD AEVQPGKRLR RVACSCPNCR EGEGRGSSEP GKKKQHVCHI 
       660        670        680        690        700
EGCGKVYGKT SHLRAHLRWH TGERPFICNW MFCGKRFTRS DELQRHRRTH 
       710        720        730        740        750
TGEKRFECPE CSKRFMRSDH LSKHVKTHQN KKGGGTALAI VTSGELDSSV 
       760        770        780 
TEVLGSPRIV TVAAISQDSN PATPNVSTNM EEF

Length:783

Mass (Da):81,984

Last modified:November 1, 1996 - v1

Checksum:ⁱ394AA6D4DEA5A197

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07065921 Genomic DNA No translation available. U07610 mRNA Translation: AAA17375.1 CH474038 Genomic DNA Translation: EDL89090.1
PIRⁱ	A48143
NCBI Reference Sequences More...RefSeqⁱ	NP_036893.1, NM_012761.1
UniGeneⁱ	Rn.9989

Genome annotation databases

Ensemblⁱ	ENSRNOT00000007625; ENSRNOP00000007625; ENSRNOG00000005472
GeneIDⁱ	25162
KEGGⁱ	rno:25162
UCSC genome browser More...UCSCⁱ	RGD:3741 rat

Protein	Similar proteins		Species	Score	Length	Source
Q63158	Zinc finger transcription factor Sp4 (Fragment)		MOUSE		39	UniRef100_Q63158

Protein	Similar proteins		Species	Score	Length	Source
Q63158	Transcription factor Sp4		HUMAN		784	UniRef90_Q02446
Transcription factor Sp4		MOUSE		782
SP4 isoform 1		PANTR		784
Uncharacterized protein		PANPA		784
Sp4 transcription factor		GORGO		784
+145

Protein	Similar proteins		Species	Score	Length	Source
Q63158	Transcription factor Sp4		HUMAN		784	UniRef50_Q02446
Transcription factor Sp4		MOUSE		782
SP4 isoform 1		PANTR		784
Uncharacterized protein		PANPA		784
Sp4 transcription factor		GORGO		784
+322

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AABR07065921 Genomic DNA No translation available. U07610 mRNA Translation: AAA17375.1 CH474038 Genomic DNA Translation: EDL89090.1
PIRⁱ	A48143
RefSeqⁱ	NP_036893.1, NM_012761.1
UniGeneⁱ	Rn.9989

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10116.ENSRNOP00000007625

STRINGⁱ

10116.ENSRNOP00000007625

Proteomic databases

PRIDEⁱ	Q63158

PRIDEⁱ

Q63158

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSRNOT00000007625; ENSRNOP00000007625; ENSRNOG00000005472
GeneIDⁱ	25162
KEGGⁱ	rno:25162
UCSCⁱ	RGD:3741 rat

Organism-specific databases

CTDⁱ	6671
RGDⁱ	3741 Sp4

Phylogenomic databases

eggNOGⁱ	KOG1721 Eukaryota COG5048 LUCA
GeneTreeⁱ	ENSGT00760000118984
HOGENOMⁱ	HOG000234295
HOVERGENⁱ	HBG008933
KOⁱ	K09194
OMAⁱ	CHMEGCG
OrthoDBⁱ	EOG091G0HX6
TreeFamⁱ	TF350150

Gene expression databases

Bgeeⁱ	ENSRNOG00000005472 Expressed in 9 organ(s), highest expression level in spleen

Bgeeⁱ

ENSRNOG00000005472 Expressed in 9 organ(s), highest expression level in spleen

Family and domain databases

InterProⁱ	View protein in InterPro IPR030453 SP4 IPR036236 Znf_C2H2_sf IPR013087 Znf_C2H2_type
PANTHERⁱ	PTHR23235:SF17 PTHR23235:SF17, 1 hit
Pfamⁱ	View protein in Pfam PF00096 zf-C2H2, 3 hits
SMARTⁱ	View protein in SMART SM00355 ZnF_C2H2, 3 hits
SUPFAMⁱ	SSF57667 SSF57667, 2 hits
PROSITEⁱ	View protein in PROSITE PS00028 ZINC_FINGER_C2H2_1, 3 hits PS50157 ZINC_FINGER_C2H2_2, 3 hits
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q63158_RAT
Accessionⁱ	Q63158Primary (citable) accession number: Q63158
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	November 1, 1996
	Last sequence update:	November 1, 1996
	Last modified:	November 7, 2018
	This is version 133 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q63158 (Q63158_RAT)

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RCG21090

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytosol

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ