Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 160 (02 Dec 2020)
Sequence version 2 (15 Aug 2003)
Previous versions | rss
Add a publicationFeedback
Protein

Apoptosis-stimulating of p53 protein 1

Gene

Ppp1r13b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Regulator that plays a central role in regulation of apoptosis via its interaction with p53/TP53 (By similarity). Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo (By similarity).By similarity

Miscellaneous

In contrast to its official gene name, it is not a regulatory subunit of protein phosphatase 1. This name was given due to its similarity with a protein that binds to protein phosphatase 1.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-6804759, Regulation of TP53 Activity through Association with Co-factors

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Apoptosis-stimulating of p53 protein 1
Alternative name(s):
Protein phosphatase 1 regulatory subunit 13B
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Ppp1r13b
Synonyms:Aspp1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1336199, Ppp1r13b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000669631 – 1087Apoptosis-stimulating of p53 protein 1Add BLAST1087

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei332PhosphoserineBy similarity1
Modified residuei335PhosphoserineBy similarity1
Modified residuei552Asymmetric dimethylarginineCombined sources1
Modified residuei679PhosphoserineBy similarity1
Modified residuei708PhosphoserineCombined sources1

Keywords - PTMi

Methylation, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q62415

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q62415

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q62415

PeptideAtlas

More...
PeptideAtlasi
Q62415

PRoteomics IDEntifications database

More...
PRIDEi
Q62415

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q62415

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q62415

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000021285, Expressed in dorsal pancreas and 253 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q62415, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q62415, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with P53/TP53; the interaction promotes pro-apoptotic activity.

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
204283, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q62415, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000062464

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q62415, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q62415

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati917 – 949ANK 1Add BLAST33
Repeati950 – 982ANK 2Add BLAST33
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1016 – 1078SH3PROSITE-ProRule annotationAdd BLAST63

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi132 – 292Gln-richAdd BLAST161
Compositional biasi446 – 857Pro-richAdd BLAST412

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The ankyrin repeats and the SH3 domain are required for a specific interactions with TP53.By similarity

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the ASPP family.Curated

Keywords - Domaini

ANK repeat, Repeat, SH3 domain

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0515, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000153463

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_008234_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q62415

Database of Orthologous Groups

More...
OrthoDBi
1041229at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q62415

TreeFam database of animal gene trees

More...
TreeFami
TF105545

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR028319, ASPP_1
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR029071, Ubiquitin-like_domsf

The PANTHER Classification System

More...
PANTHERi
PTHR24131:SF5, PTHR24131:SF5, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796, Ank_2, 1 hit
PF00018, SH3_1, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00452, SH3DOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248, ANK, 2 hits
SM00326, SH3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403, SSF48403, 1 hit
SSF50044, SSF50044, 1 hit
SSF54236, SSF54236, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50002, SH3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q62415-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MMPMILTVFL SNNEQILTEV PITPETTCRD VVEFCKEPGE GGCHLAEVWR
60 70 80 90 100
GSERPIPYDH MMYEHLQKWG PRREEVKFFL RHEDSPTESS EQGARQTQEQ
110 120 130 140 150
RTQRSVVNVP GEKRTENGVG NPRVELTLSE LQDMAARQQQ QIENQQQMLV
160 170 180 190 200
AKEQRLHFLK QQERRQQQSV SENEKLQKLK ERVEAQENKL KKIRAMRGQV
210 220 230 240 250
DYSKIMNGNL SAEIERFSAM FQEKKQEVQT AILRVDQLSQ QLEDLKKGKL
260 270 280 290 300
NGFQSYNGRL TGPAAVELKR LYQELQIRNQ LNQEQNSKLQ QQKELLNKRN
310 320 330 340 350
MEVAMMDKRI SELRERLYGK KIQLNRVNGT SSPQSPLSTS GRVAAVGPYI
360 370 380 390 400
QVPSTGGFPL PGDPVKPQSL TIASSAAHGR SKSANDGNWP PLKQNSASVK
410 420 430 440 450
STQMTGDWKD SGMEGTLKQG AISSQPLPLS ALGATEKLGI EIGKGPPPIP
460 470 480 490 500
GVGKPLPPSY GTYPSSGPLG PGSTSSLERR KEGSLPRPGA GPPSRQKPAP
510 520 530 540 550
LPPASNAPQP GSSQQIQQRI SVPPSPTYPP AGPPAFPTGD GKPELPLTVA
560 570 580 590 600
IRPFLADKGS RPQSPRKGPQ TVNSSSIYSM YLQQATPPKN YQPPAHGTLN
610 620 630 640 650
KSVKAVYGKP VLPSGSASPS PLPFLHGSLG TGTAQPQPPS DSAEKEPEQE
660 670 680 690 700
GPSVPGEGST VESLPRPLSP TKLTPIVHSP LRYQSDADLE ALRRKLANAP
710 720 730 740 750
RPLKKRSSIT EPEGPGGPNI QKLLYQRFNT LAGGMEGTPF YQPSPSQDFV
760 770 780 790 800
GTLADMDNGN TNANGNLDEP FPPRPTAPLP EELAPSSDAN DNELPSPEPE
810 820 830 840 850
ELICPQTTHQ TAEPTEDNNN NVAPVPSTEQ IPSPVAEAPS EEDQVPPAPL
860 870 880 890 900
SPVIHPPAAS ASKRTNLKKP NSERTGHGLR VRFNPLALLL DASLEGEFDL
910 920 930 940 950
VQRIIYEVED PSKPNDEGIT PLHNAVCAGH HHIVKFLLDF GVNVNAADSD
960 970 980 990 1000
GWTPLHCAAS CNSVHLCKQL VESGAAIFAS TISDIETAAD KCEEMEEGYI
1010 1020 1030 1040 1050
QCSQFLYGVQ EKLGVMNKGT VYALWDYEAQ NSDELSFHEG DAITILRRKD
1060 1070 1080
ENETEWWWAR LGDREGYVPK NLLGLYPRIK PRQRTLA
Length:1,087
Mass (Da):119,170
Last modified:August 15, 2003 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8B3E9CC4B2390F13
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1Y7VJH3A0A1Y7VJH3_MOUSE
Apoptosis-stimulating of p53 protei...
Ppp1r13b
964Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC054788 mRNA Translation: AAH54788.1
BC053092 mRNA Translation: AAH53092.1
U58881 mRNA Translation: AAC52638.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS56866.1

NCBI Reference Sequences

More...
RefSeqi
NP_035755.1, NM_011625.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000054815; ENSMUSP00000062464; ENSMUSG00000021285

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
21981

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:21981

UCSC genome browser

More...
UCSCi
uc007ped.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC054788 mRNA Translation: AAH54788.1
BC053092 mRNA Translation: AAH53092.1
U58881 mRNA Translation: AAC52638.1
CCDSiCCDS56866.1
RefSeqiNP_035755.1, NM_011625.1

3D structure databases

SMRiQ62415
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi204283, 10 interactors
IntActiQ62415, 1 interactor
STRINGi10090.ENSMUSP00000062464

PTM databases

iPTMnetiQ62415
PhosphoSitePlusiQ62415

Proteomic databases

EPDiQ62415
MaxQBiQ62415
PaxDbiQ62415
PeptideAtlasiQ62415
PRIDEiQ62415

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
87, 218 antibodies

Genome annotation databases

EnsembliENSMUST00000054815; ENSMUSP00000062464; ENSMUSG00000021285
GeneIDi21981
KEGGimmu:21981
UCSCiuc007ped.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23368
MGIiMGI:1336199, Ppp1r13b

Phylogenomic databases

eggNOGiKOG0515, Eukaryota
GeneTreeiENSGT00940000153463
HOGENOMiCLU_008234_0_0_1
InParanoidiQ62415
OrthoDBi1041229at2759
PhylomeDBiQ62415
TreeFamiTF105545

Enzyme and pathway databases

ReactomeiR-MMU-6804759, Regulation of TP53 Activity through Association with Co-factors

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
21981, 0 hits in 18 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Ppp1r13b, mouse

Protein Ontology

More...
PROi
PR:Q62415
RNActiQ62415, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000021285, Expressed in dorsal pancreas and 253 other tissues
ExpressionAtlasiQ62415, baseline and differential
GenevisibleiQ62415, MM

Family and domain databases

Gene3Di1.25.40.20, 1 hit
InterProiView protein in InterPro
IPR002110, Ankyrin_rpt
IPR020683, Ankyrin_rpt-contain_dom
IPR036770, Ankyrin_rpt-contain_sf
IPR028319, ASPP_1
IPR036028, SH3-like_dom_sf
IPR001452, SH3_domain
IPR029071, Ubiquitin-like_domsf
PANTHERiPTHR24131:SF5, PTHR24131:SF5, 1 hit
PfamiView protein in Pfam
PF12796, Ank_2, 1 hit
PF00018, SH3_1, 1 hit
PRINTSiPR00452, SH3DOMAIN
SMARTiView protein in SMART
SM00248, ANK, 2 hits
SM00326, SH3, 1 hit
SUPFAMiSSF48403, SSF48403, 1 hit
SSF50044, SSF50044, 1 hit
SSF54236, SSF54236, 1 hit
PROSITEiView protein in PROSITE
PS50297, ANK_REP_REGION, 1 hit
PS50088, ANK_REPEAT, 2 hits
PS50002, SH3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiASPP1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q62415
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: August 15, 2003
Last modified: December 2, 2020
This is version 160 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again