UniProtKB - Q62230 (SN_MOUSE)
Protein
Sialoadhesin
Gene
Siglec1
Organism
Mus musculus (Mouse)
Status
Functioni
Acts as an endocytic receptor mediating clathrin dependent endocytosis. Macrophage-restricted adhesion molecule that mediates sialic-acid dependent binding to lymphocytes, including granulocytes, monocytes, natural killer cells, B-cells and CD8 T-cells (By similarity). Preferentially binds to alpha-2,3-linked sialic acid. Binds to SPN/CD43 on T-cells. May play a role in hematopoiesis. May act as a counter-receptor for CLEC10A in lymph node.By similarity1 Publication
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 63 | Sialic acid1 Publication | 1 | |
Binding sitei | 116 | Sialic acid4 Publications | 1 |
GO - Molecular functioni
- carbohydrate binding Source: UniProtKB-KW
GO - Biological processi
- cell adhesion Source: UniProtKB-KW
- endocytosis Source: UniProtKB-KW
- positive regulation of extrinsic apoptotic signaling pathway Source: MGI
- positive regulation of T cell apoptotic process Source: MGI
Keywordsi
Biological process | Cell adhesion, Endocytosis |
Ligand | Lectin |
Enzyme and pathway databases
Reactomei | R-MMU-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
Protein family/group databases
UniLectini | Q62230 |
Names & Taxonomyi
Protein namesi | Recommended name: SialoadhesinAlternative name(s): Sheep erythrocyte receptor Short name: SER Sialic acid-binding Ig-like lectin 1 Short name: Siglec-1 CD_antigen: CD169 |
Gene namesi | Name:Siglec1 Synonyms:Sa, Sn |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:99668 Siglec1 |
Subcellular locationi
Isoform 1 :
Plasma membrane
Extracellular region or secreted
- extracellular region Source: UniProtKB-SubCell
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 20 – 1639 | ExtracellularSequence analysisAdd BLAST | 1620 | |
Transmembranei | 1640 – 1660 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 1661 – 1695 | CytoplasmicSequence analysisAdd BLAST | 35 |
Keywords - Cellular componenti
Cell membrane, Membrane, SecretedPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 21 | W → Q: Loss of sialic acid binding. 1 Publication | 1 | |
Mutagenesisi | 116 | R → A: Loss of sialic acid binding. 1 Publication | 1 | |
Mutagenesisi | 116 | R → L: 10-fold loss in affinity to sialic acid. 1 Publication | 1 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Add BLAST | 19 | |
ChainiPRO_0000014969 | 20 – 1695 | SialoadhesinAdd BLAST | 1676 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Disulfide bondi | 36 ↔ 166 | PROSITE-ProRule annotation | ||
Disulfide bondi | 41 ↔ 98 | PROSITE-ProRule annotation1 Publication | ||
Glycosylationi | 159 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 160 ↔ 218 | PROSITE-ProRule annotation | ||
Disulfide bondi | 263 ↔ 306 | PROSITE-ProRule annotation | ||
Glycosylationi | 266 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 299 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 340 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 347 ↔ 391 | PROSITE-ProRule annotation | ||
Disulfide bondi | 434 ↔ 492 | PROSITE-ProRule annotation | ||
Glycosylationi | 500 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 532 ↔ 576 | PROSITE-ProRule annotation | ||
Glycosylationi | 583 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 625 ↔ 685 | PROSITE-ProRule annotation | ||
Glycosylationi | 693 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 722 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 725 ↔ 770 | PROSITE-ProRule annotation | ||
Glycosylationi | 737 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 813 ↔ 872 | PROSITE-ProRule annotation | ||
Glycosylationi | 882 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 912 ↔ 956 | PROSITE-ProRule annotation | ||
Disulfide bondi | 1001 ↔ 1063 | PROSITE-ProRule annotation | ||
Glycosylationi | 1090 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 1100 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 1103 ↔ 1145 | PROSITE-ProRule annotation | ||
Disulfide bondi | 1189 ↔ 1237 | PROSITE-ProRule annotation | ||
Glycosylationi | 1247 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 1277 ↔ 1320 | PROSITE-ProRule annotation | ||
Disulfide bondi | 1363 ↔ 1422 | PROSITE-ProRule annotation | ||
Glycosylationi | 1460 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 1463 ↔ 1509 | PROSITE-ProRule annotation | ||
Glycosylationi | 1474 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 1552 ↔ 1611 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
jPOSTi | Q62230 |
PaxDbi | Q62230 |
PRIDEi | Q62230 |
PTM databases
iPTMneti | Q62230 |
PhosphoSitePlusi | Q62230 |
Expressioni
Tissue specificityi
Detected in lymph node in the subcapsular sinus, interfollicular regions, and T and B-cell boundary (at protein level). Expressed by macrophages in various tissues. Highest expression in spleen and lymph node with lower amounts in lung, liver, bone marrow, heart and skin. No expression in thymus, kidney, brain or small intestine.1 Publication
Interactioni
Subunit structurei
Interacts with CLEC10A.
5 PublicationsProtein-protein interaction databases
BioGridi | 203360, 2 interactors |
IntActi | Q62230, 3 interactors |
MINTi | Q62230 |
STRINGi | 10090.ENSMUSP00000028794 |
Structurei
Secondary structure
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details3D structure databases
SMRi | Q62230 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q62230 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 20 – 136 | Ig-like V-typeAdd BLAST | 117 | |
Domaini | 153 – 235 | Ig-like C2-type 1Add BLAST | 83 | |
Domaini | 239 – 321 | Ig-like C2-type 2Add BLAST | 83 | |
Domaini | 326 – 406 | Ig-like C2-type 3Add BLAST | 81 | |
Domaini | 416 – 508 | Ig-like C2-type 4Add BLAST | 93 | |
Domaini | 509 – 594 | Ig-like C2-type 5Add BLAST | 86 | |
Domaini | 602 – 701 | Ig-like C2-type 6Add BLAST | 100 | |
Domaini | 704 – 781 | Ig-like C2-type 7Add BLAST | 78 | |
Domaini | 795 – 890 | Ig-like C2-type 8Add BLAST | 96 | |
Domaini | 894 – 973 | Ig-like C2-type 9Add BLAST | 80 | |
Domaini | 980 – 1079 | Ig-like C2-type 10Add BLAST | 100 | |
Domaini | 1081 – 1161 | Ig-like C2-type 11Add BLAST | 81 | |
Domaini | 1172 – 1264 | Ig-like C2-type 12Add BLAST | 93 | |
Domaini | 1245 – 1337 | Ig-like C2-type 13Add BLAST | 93 | |
Domaini | 1342 – 1439 | Ig-like C2-type 14Add BLAST | 98 | |
Domaini | 1442 – 1520 | Ig-like C2-type 15Add BLAST | 79 | |
Domaini | 1534 – 1627 | Ig-like C2-type 16Add BLAST | 94 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 122 – 126 | Sialic acid binding | 5 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 827 – 829 | Cell attachment siteSequence analysis | 3 |
Sequence similaritiesi
Belongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.Curated
Keywords - Domaini
Immunoglobulin domain, Repeat, Signal, Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | ENOG410KDW5 Eukaryota ENOG410ZJZH LUCA |
HOGENOMi | HOG000154365 |
InParanoidi | Q62230 |
KOi | K06548 |
OrthoDBi | 54136at2759 |
Family and domain databases
Gene3Di | 2.60.40.10, 17 hits |
InterProi | View protein in InterPro IPR013162 CD80_C2-set IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR013098 Ig_I-set IPR003599 Ig_sub IPR003598 Ig_sub2 IPR013106 Ig_V-set IPR013151 Immunoglobulin |
Pfami | View protein in Pfam PF08205 C2-set_2, 1 hit PF07679 I-set, 3 hits PF00047 ig, 1 hit PF13895 Ig_2, 6 hits PF07686 V-set, 1 hit |
SMARTi | View protein in SMART SM00409 IG, 16 hits SM00408 IGc2, 15 hits |
SUPFAMi | SSF48726 SSF48726, 12 hits |
PROSITEi | View protein in PROSITE PS50835 IG_LIKE, 14 hits |
s (3+)i Sequence
Sequence statusi: Complete.
: The displayed sequence is further processed into a mature form. Sequence processingi
This entry describes 3 produced by isoformsialternative splicing. AlignAdd to basketThis entry has 3 described isoforms and 3 potential isoforms that are computationally mapped.Show allAlign All
Isoform 1 (identifier: Q62230-1) [UniParc]FASTAAdd to basket
This isoform has been chosen as the sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry. canonicali
10 20 30 40 50
MCVLFSLLLL ASVFSLGQTT WGVSSPKNVQ GLSGSCLLIP CIFSYPADVP
60 70 80 90 100
VSNGITAIWY YDYSGKRQVV IHSGDPKLVD KRFRGRAELM GNMDHKVCNL
110 120 130 140 150
LLKDLKPEDS GTYNFRFEIS DSNRWLDVKG TTVTVTTDPS PPTITIPEEL
160 170 180 190 200
REGMERNFNC STPYLCLQEK QVSLQWRGQD PTHSVTSSFQ SLEPTGVYHQ
210 220 230 240 250
TTLHMALSWQ DHGRTLLCQF SLGAHSSRKE VYLQVPHAPK GVEILLSSSG
260 270 280 290 300
RNILPGDPVT LTCRVNSSYP AVSAVQWARD GVNLGVTGHV LRLFSAAWND
310 320 330 340 350
SGAYTCQATN DMGSLVSSPL SLHVFMAEVK MNPAGPVLEN ETVTLLCSTP
360 370 380 390 400
KEAPQELRYS WYKNHILLED AHASTLHLPA VTRADTGFYF CEVQNAQGSE
410 420 430 440 450
RSSPLSVVVR YPPLTPDLTT FLETQAGLVG ILHCSVVSEP LATVVLSHGG
460 470 480 490 500
LTLASNSGEN DFNPRFRISS APNSLRLEIR DLQPADSGEY TCLAVNSLGN
510 520 530 540 550
STSSLDFYAN VARLLINPSA EVVEGQAVTL SCRSGLSPAP DTRFSWYLNG
560 570 580 590 600
ALLLEGSSSS LLLPAASSTD AGSYYCRTQA GPNTSGPSLP TVLTVFYPPR
610 620 630 640 650
KPTFTARLDL DTSGVGDGRR GILLCHVDSD PPAQLRLLHK GHVVATSLPS
660 670 680 690 700
RCGSCSQRTK VSRTSNSLHV EIQKPVLEDE GVYLCEASNT LGNSSAAASF
710 720 730 740 750
NAKATVLVIT PSNTLREGTE ANLTCNVNQE VAVSPANFSW FRNGVLWTQG
760 770 780 790 800
SLETVRLQPV ARTDAAVYAC RLLTEDGAQL SAPVVLSVLY APDPPKLSAL
810 820 830 840 850
LDVGQGHMAV FICTVDSYPL AHLSLFRGDH LLATNLEPQR PSHGRIQAKA
860 870 880 890 900
TANSLQLEVR ELGLVDSGNY HCEATNILGS ANSSLFFQVR GAWVQVSPSP
910 920 930 940 950
ELREGQAVVL SCQVPTGVSE GTSYSWYQDG RPLQESTSST LRIAAISLRQ
960 970 980 990 1000
AGAYHCQAQA PDTAIASLAA PVSLHVSYTP RHVTLSALLS TDPERLGHLV
1010 1020 1030 1040 1050
CSVQSDPPAQ LQLFHRNRLV ASTLQGADEL AGSNPRLHVT VLPNELRLQI
1060 1070 1080 1090 1100
HFPELEDDGT YTCEASNTLG QASAAADFDA QAVRVTVWPN ATVQEGQQVN
1110 1120 1130 1140 1150
LTCLVWSTHQ DSLSYTWYKG GQQLLGARSI TLPSVKVLDA TSYRCGVGLP
1160 1170 1180 1190 1200
GHAPHLSRPV TLDVLHAPRN LRLTYLLETQ GRQLALVLCT VDSRPPAQLT
1210 1220 1230 1240 1250
LSHGDQLVAS STEASVPNTL RLELQDPRPS NEGLYSCSAH SPLGKANTSL
1260 1270 1280 1290 1300
ELLLEGVRVK MNPSGSVPEG EPVTVTCEDP AALSSALYAW FHNGHWLQEG
1310 1320 1330 1340 1350
PASSLQFLVT TRAHAGAYFC QVHDTQGTRS SRPASLQILY APRDAVLSSF
1360 1370 1380 1390 1400
RDSRTRLMVV IQCTVDSEPP AEMVLSHNGK VLAASHERHS SASGIGHIQV
1410 1420 1430 1440 1450
ARNALRLQVQ DVTLGDGNTY VCTAQNTLGS ISTTQRLLTE TDIRVTAEPG
1460 1470 1480 1490 1500
LDVPEGTALN LSCLLPGGSG PTGNSSFTWF WNRHRLHSAP VPTLSFTPVV
1510 1520 1530 1540 1550
RAQAGLYHCR ADLPTGATTS APVMLRVLYP PKTPTLIVFV EPQGGHQGIL
1560 1570 1580 1590 1600
DCRVDSEPLA ILTLHRGSQL VASNQLHDAP TKPHIRVTAP PNALRVDIEE
1610 1620 1630 1640 1650
LGPSNQGEYV CTASNTLGSA SASAYFGTRA LHQLQLFQRL LWVLGFLAGF
1660 1670 1680 1690
LCLLLGLVAY HTWRKKSSTK LNEDENSAEM ATKKNTIQEE VVAAL
Computationally mapped potential isoform sequencesi
There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketG3X8X6 | G3X8X6_MOUSE | Sialic acid binding Ig-like lectin ... | Siglec1 mCG_18494 | 1,701 | Annotation score: | ||
H9KUZ2 | H9KUZ2_MOUSE | Sialoadhesin | Siglec1 | 346 | Annotation score: | ||
H9KUZ3 | H9KUZ3_MOUSE | Sialic acid binding Ig-like lectin ... | Siglec1 mCG_18494 | 1,605 | Annotation score: |
Sequence cautioni
The sequence CAA85268 differs from that shown. Reason: Frameshift.Curated
The sequence CAA85290 differs from that shown. Reason: Frameshift.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 159 | N → F in AAB95641 (PubMed:9383289).Curated | 1 | |
Sequence conflicti | 197 | V → S in CAA85268 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 197 | V → S in CAA85290 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 197 | V → S in AAB95641 (PubMed:9383289).Curated | 1 | |
Sequence conflicti | 590 | P → Q AA sequence (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 727 | V → G in CAA85268 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 727 | V → G in CAA85290 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 727 | V → G in AAB95641 (PubMed:9383289).Curated | 1 | |
Sequence conflicti | 759 – 760 | PV → LL in CAA85268 (PubMed:7925291).Curated | 2 | |
Sequence conflicti | 759 – 760 | PV → LL in CAA85290 (PubMed:7925291).Curated | 2 | |
Sequence conflicti | 759 – 760 | PV → LL in AAB95641 (PubMed:9383289).Curated | 2 | |
Sequence conflicti | 1050 – 1052 | IHF → FLV AA sequence (PubMed:7925291).Curated | 3 | |
Sequence conflicti | 1055 – 1056 | LE → VQ AA sequence (PubMed:7925291).Curated | 2 | |
Sequence conflicti | 1062 | T → Q AA sequence (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 1066 | S → Q AA sequence (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 1426 | N → H in CAA85268 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 1426 | N → H in CAA85290 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 1426 | N → H in AAB95641 (PubMed:9383289).Curated | 1 | |
Sequence conflicti | 1453 | V → W in CAA85268 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 1453 | V → W in CAA85290 (PubMed:7925291).Curated | 1 | |
Sequence conflicti | 1453 | V → W in AAB95641 (PubMed:9383289).Curated | 1 |
Alternative sequence
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Alternative sequenceiVSP_002573 | 326 – 340 | MAEVK…PVLEN → SESWMRLRGPVSGKH in isoform 2. 1 PublicationAdd BLAST | 15 | |
Alternative sequenceiVSP_002574 | 341 – 1695 | Missing in isoform 2. 1 PublicationAdd BLAST | 1355 | |
Alternative sequenceiVSP_002575 | 1529 – 1599 | YPPKT…RVDIE → CEYEPISALCLSLHLTGPYQ AFSSAQSKGFIGKGLRTLAS SLAGCMWFVSMLGYPALKWR ILLPFWDEYRR in isoform 3. 1 PublicationAdd BLAST | 71 | |
Alternative sequenceiVSP_002576 | 1600 – 1695 | Missing in isoform 3. 1 PublicationAdd BLAST | 96 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z36293 mRNA Translation: CAA85290.1 Frameshift. Z36233 mRNA Translation: CAA85268.1 Frameshift. Z36234 mRNA Translation: CAA85269.1 U92842 U92841 Genomic DNA Translation: AAB95641.1 AL831736 Genomic DNA No translation available. AL833771 Genomic DNA No translation available. |
PIRi | S50065 |
RefSeqi | NP_035556.3, NM_011426.3 |
Genome annotation databases
GeneIDi | 20612 |
KEGGi | mmu:20612 |
UCSCi | uc008mkp.1 mouse [Q62230-3] uc008mkq.1 mouse [Q62230-2] |
Keywords - Coding sequence diversityi
Alternative splicingSimilar proteinsi
Cross-referencesi
Web resourcesi
Functional Glycomics Gateway - Glycan Binding Siglec-1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | Z36293 mRNA Translation: CAA85290.1 Frameshift. Z36233 mRNA Translation: CAA85268.1 Frameshift. Z36234 mRNA Translation: CAA85269.1 U92842 U92841 Genomic DNA Translation: AAB95641.1 AL831736 Genomic DNA No translation available. AL833771 Genomic DNA No translation available. |
PIRi | S50065 |
RefSeqi | NP_035556.3, NM_011426.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1OD7 | X-ray | 3.00 | A | 20-138 | [»] | |
1OD9 | X-ray | 2.10 | A | 20-138 | [»] | |
1ODA | X-ray | 3.31 | A | 20-138 | [»] | |
1QFO | X-ray | 1.85 | A/B/C | 20-138 | [»] | |
1QFP | X-ray | 2.80 | A | 20-138 | [»] | |
1URL | X-ray | 2.40 | A | 20-137 | [»] | |
2BVE | X-ray | 2.20 | A/B | 20-138 | [»] | |
SMRi | Q62230 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGridi | 203360, 2 interactors |
IntActi | Q62230, 3 interactors |
MINTi | Q62230 |
STRINGi | 10090.ENSMUSP00000028794 |
Protein family/group databases
UniLectini | Q62230 |
PTM databases
iPTMneti | Q62230 |
PhosphoSitePlusi | Q62230 |
Proteomic databases
jPOSTi | Q62230 |
PaxDbi | Q62230 |
PRIDEi | Q62230 |
Genome annotation databases
GeneIDi | 20612 |
KEGGi | mmu:20612 |
UCSCi | uc008mkp.1 mouse [Q62230-3] uc008mkq.1 mouse [Q62230-2] |
Organism-specific databases
CTDi | 6614 |
MGIi | MGI:99668 Siglec1 |
Phylogenomic databases
eggNOGi | ENOG410KDW5 Eukaryota ENOG410ZJZH LUCA |
HOGENOMi | HOG000154365 |
InParanoidi | Q62230 |
KOi | K06548 |
OrthoDBi | 54136at2759 |
Enzyme and pathway databases
Reactomei | R-MMU-198933 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
Miscellaneous databases
EvolutionaryTracei | Q62230 |
PROi | PR:Q62230 |
SOURCEi | Search... |
Family and domain databases
Gene3Di | 2.60.40.10, 17 hits |
InterProi | View protein in InterPro IPR013162 CD80_C2-set IPR007110 Ig-like_dom IPR036179 Ig-like_dom_sf IPR013783 Ig-like_fold IPR013098 Ig_I-set IPR003599 Ig_sub IPR003598 Ig_sub2 IPR013106 Ig_V-set IPR013151 Immunoglobulin |
Pfami | View protein in Pfam PF08205 C2-set_2, 1 hit PF07679 I-set, 3 hits PF00047 ig, 1 hit PF13895 Ig_2, 6 hits PF07686 V-set, 1 hit |
SMARTi | View protein in SMART SM00409 IG, 16 hits SM00408 IGc2, 15 hits |
SUPFAMi | SSF48726 SSF48726, 12 hits |
PROSITEi | View protein in PROSITE PS50835 IG_LIKE, 14 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SN_MOUSE | |
Accessioni | Q62230Primary (citable) accession number: Q62230 Secondary accession number(s): D3YVZ3 Q62229 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | May 30, 2000 |
Last sequence update: | September 21, 2011 | |
Last modified: | October 16, 2019 | |
This is version 168 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Complete proteome, Direct protein sequencing, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references