Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Outer dense fiber protein 1

Gene

Odf1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental protein
Biological processDifferentiation, Spermatogenesis

Names & Taxonomyi

Protein namesi
Recommended name:
Outer dense fiber protein 1
Gene namesi
Name:Odf1
Synonyms:Odfp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:97424 Odf1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000580251 – 247Outer dense fiber protein 1Add BLAST247

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei5PhosphoserineBy similarity1
Modified residuei10PhosphoserineBy similarity1
Modified residuei64PhosphoserineBy similarity1
Modified residuei87PhosphoserineBy similarity1
Modified residuei108PhosphoserineBy similarity1
Modified residuei109PhosphoserineBy similarity1
Modified residuei137PhosphoserineBy similarity1
Modified residuei153PhosphoserineBy similarity1
Modified residuei175PhosphoserineBy similarity1
Modified residuei180PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

PaxDbiQ61999
PRIDEiQ61999

PTM databases

iPTMnetiQ61999
PhosphoSitePlusiQ61999

Expressioni

Gene expression databases

CleanExiMM_ODF1

Interactioni

Subunit structurei

Interact (via leucine zipper motif) with TCP11 (By similarity). Interacts with SPAG4 (By similarity). Interacts with KLC3 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080632

Structurei

3D structure databases

ProteinModelPortaliQ61999
SMRiQ61999
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati34 – 3815
Repeati74 – 7825

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni34 – 782 X 5 AA repeats of [RC]-C-L-C-DAdd BLAST45
Regioni195 – 235C-X-P repeat regionAdd BLAST41

Domaini

The C-terminal contains many C-X-P repeats.

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiENOG410IHKT Eukaryota
ENOG4111C5F LUCA
HOVERGENiHBG007863
InParanoidiQ61999

Family and domain databases

CDDicd06482 ACD_HspB10, 1 hit
Gene3Di2.60.40.790, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR008978 HSP20-like_chaperone
IPR037552 ODF1_ACD
IPR037389 ODFP
PANTHERiPTHR17125 PTHR17125, 1 hit
PfamiView protein in Pfam
PF00011 HSP20, 1 hit
SUPFAMiSSF49764 SSF49764, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q61999-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAALSCLLDS VRRDIKKVDR ELRQLRCIDE ISSRCLCDLY MHPYCCCDLH
60 70 80 90 100
PYPYCLCYSK RSRSCGLCDL YYPCCLCDYK LYCLRPSLRS LERLRRTTNR
110 120 130 140 150
ILASSCCSSN ILGSVNVCGF EPDQVKVRVK DGKVCVSAER ENRYDCLGSK
160 170 180 190 200
KYSYMNICKE FSLPPCVDEK DVTYSYGLGS CVKIESPCYP CTSPCNPCNP
210 220 230 240
CSPCSPCAPC ACGPCGPCGP CGPCGPCDPC NPCYPCGSRF SCRKMIL
Length:247
Mass (Da):27,539
Last modified:November 1, 1997 - v1
Checksum:i821EB57C2D67E458
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A6H656A6H656_MOUSE
Odf1 protein
Odf1 mCG_122467
248Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79446 mRNA Translation: CAA55965.1
PIRiI48699
UniGeneiMm.252830

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X79446 mRNA Translation: CAA55965.1
PIRiI48699
UniGeneiMm.252830

3D structure databases

ProteinModelPortaliQ61999
SMRiQ61999
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000080632

PTM databases

iPTMnetiQ61999
PhosphoSitePlusiQ61999

Proteomic databases

PaxDbiQ61999
PRIDEiQ61999

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:97424 Odf1

Phylogenomic databases

eggNOGiENOG410IHKT Eukaryota
ENOG4111C5F LUCA
HOVERGENiHBG007863
InParanoidiQ61999

Miscellaneous databases

PROiPR:Q61999
SOURCEiSearch...

Gene expression databases

CleanExiMM_ODF1

Family and domain databases

CDDicd06482 ACD_HspB10, 1 hit
Gene3Di2.60.40.790, 1 hit
InterProiView protein in InterPro
IPR002068 A-crystallin/Hsp20_dom
IPR008978 HSP20-like_chaperone
IPR037552 ODF1_ACD
IPR037389 ODFP
PANTHERiPTHR17125 PTHR17125, 1 hit
PfamiView protein in Pfam
PF00011 HSP20, 1 hit
SUPFAMiSSF49764 SSF49764, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiODFP1_MOUSE
AccessioniPrimary (citable) accession number: Q61999
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: July 18, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again