UniProtKB - Q61545 (EWS_MOUSE)

BLAST

>sp|Q61545|EWS_MOUSE RNA-binding protein EWS OS=Mus musculus OX=10090 GN=Ewsr1 PE=1 SV=2
MASTDYSTYSQAAAQQGYSAYTAQPTQGYAQTTQAYGQQSYGTYGQPTDVSYTQAQTTAT
YGQTAYATSYGQPPTGYSTPTAPQAYSQPVQGYGTGTYDSTTATVTTTQASYAAQTAYGT
QPAYPTYGQQPTATAPTRPQDGNKPAETSQPQSSTGGYNQPSLGYGQSNYSYPQVPGSYP
MQPVTAPPSYPPTSYSSSQPTSYDQSSYSQQNTYGQPSSYGQQSSYGQQSSYGQQPPTSY
PPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSLSGPDNR
GRGRGGFDRGGMSRGGRGGGRGGLGAGERGGFNKPGGPMDEGPDLDLGLPIDPDEDSDNS
AIYVQGLNDNVTLDDLADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPP
TAKAAVEWFDGKDFQGSKLKVSLARKKPPMNSMRGGMPPREGRGMPPPLRGGPGGPGGPG
GPMGRMGGRGGDRGGFPPRGPRGSRGNPSGGGNVQHRAGDWQCPNPGCGNQNFAWRTECN
QCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGPGGMFRGGRGGDRGGFRG
GRGMDRGGFGGGRRGGPGGPPGPLMEQMGGRRGGRGGPGKMDKGEHRQERRDRPY

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History
Entry version 171 (12 Sep 2018)
Sequence version 2 (27 Jul 2011)
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Protein

RNA-binding protein EWS

Gene

Ewsr1

Organism

Mus musculus (Mouse)

Status

Reviewed-Annotation score: -Experimental evidence at protein levelⁱ

Functionⁱ

Might function as a transcriptional repressor.By similarity

Miscellaneous

Binds calmodulin in the presence, but not in the absence, of calcium ion.By similarity

Regions

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	517 – 548	RanBP2-typePROSITE-ProRule annotationAdd BLAST		32

GO - Molecular functionⁱ

calmodulin binding Source: UniProtKB-KW
identical protein binding Source: Ensembl
metal ion binding Source: UniProtKB-KW
RNA binding Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

GO - Biological processⁱ

regulation of transcription, DNA-templated Source: UniProtKB-KW
transcription, DNA-templated Source: UniProtKB-KW

View the complete GO annotation on QuickGO ...

Keywordsⁱ

Molecular function	Calmodulin-binding, Repressor, RNA-binding
Biological process	Transcription, Transcription regulation
Ligand	Metal-binding, Zinc

Names & Taxonomyⁱ

Protein namesⁱ	Recommended name: RNA-binding protein EWS
Gene namesⁱ	Name:Ewsr1 Synonyms:Ews, Ewsh
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 11

Organism-specific databases

MGIⁱ	MGI:99960 Ewsr1

Keywords - Cellular componentⁱ

Cell membrane, Cytoplasm, Membrane, Nucleus

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
ChainⁱPRO_0000081587	1 – 655	RNA-binding protein EWSAdd BLAST		655

Amino acid modifications

Feature key	Position(s)	DescriptionActions	Length
Modified residueⁱ	266	Phosphoserine; by PKCBy similarity	1
Modified residueⁱ	300	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	302	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	304	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	309	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	314	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	317	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	321	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	438	N6-acetyllysineCombined sources	1
Modified residueⁱ	454	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	463	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	470	Asymmetric dimethylarginine; alternateBy similarity	1
Modified residueⁱ	470	Omega-N-methylarginine; alternateCombined sources	1
Modified residueⁱ	485	Omega-N-methylarginineCombined sources	1
Modified residueⁱ	489	Asymmetric dimethylarginine; by PRMT8By similarity	1
Modified residueⁱ	493	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	499	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	502	Asymmetric dimethylarginineCombined sources	1
Modified residueⁱ	505	Asymmetric dimethylarginine; alternateCombined sources	1
Modified residueⁱ	505	Omega-N-methylarginine; alternateCombined sources	1
Modified residueⁱ	562	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	564	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	571	Asymmetric dimethylarginine; alternate; by PRMT8By similarity	1
Modified residueⁱ	571	Omega-N-methylarginine; alternate; by PRMT8By similarity	1
Modified residueⁱ	574	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	580	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	588	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	591	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	595	Asymmetric dimethylarginine; alternate; by PRMT8By similarity	1
Modified residueⁱ	595	Omega-N-methylarginine; alternate; by PRMT8By similarity	1
Modified residueⁱ	599	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	602	Asymmetric dimethylarginine; by PRMT8By similarity	1
Modified residueⁱ	606	Asymmetric dimethylarginine; alternate; by PRMT8By similarity	1
Modified residueⁱ	606	Omega-N-methylarginine; alternate; by PRMT8By similarity	1
Modified residueⁱ	614	Asymmetric dimethylarginine; alternateCombined sources	1
Modified residueⁱ	614	Omega-N-methylarginine; alternateCombined sources	1
Modified residueⁱ	632	Asymmetric dimethylarginineBy similarity	1
Modified residueⁱ	635	Asymmetric dimethylarginineBy similarity	1

Post-translational modificationⁱ

Phosphorylated; calmodulin-binding inhibits phosphorylation of Ser-266.By similarity

Highly methylated on arginine residues. Methylation is mediated by PRMT1 and, at lower level by PRMT8 (By similarity).By similarity

Keywords - PTMⁱ

Acetylation, Methylation, Phosphoprotein

Proteomic databases

EPDⁱ	Q61545
MaxQB - The MaxQuant DataBase More...MaxQBⁱ	Q61545
PaxDbⁱ	Q61545
PRIDEⁱ	Q61545

PTM databases

iPTMnetⁱ	Q61545
PhosphoSitePlusⁱ	Q61545
SwissPalmⁱ	Q61545

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000009079 Expressed in 301 organ(s), highest expression level in urinary bladder
CleanExⁱ	MM_EWSR1
ExpressionAtlasⁱ	Q61545 baseline and differential
Genevisibleⁱ	Q61545 MM

Interactionⁱ

Subunit structureⁱ

Binds RNA, POLR2C, SF1 and calmodulin. Interacts with PTK2B and TDRD3 (By similarity).By similarity

Binary interactionsⁱ

With	Entry	#Exp.	IntAct	Notes
Pou5f1	P20263	13	EBI-1606991,EBI-1606219

With

Entry

#Exp.

IntAct

Notes

Pou5f1

P20263

EBI-1606991,EBI-1606219

GO - Molecular functionⁱ

calmodulin binding Source: UniProtKB-KW
identical protein binding Source: Ensembl

View the complete GO annotation on QuickGO ...

Protein-protein interaction databases

BioGridⁱ	199551, 73 interactors
IntActⁱ	Q61545, 17 interactors
Molecular INTeraction database More...MINTⁱ	Q61545
STRINGⁱ	10090.ENSMUSP00000078867

Structureⁱ

3D structure databases

ProteinModelPortalⁱ	Q61545
SMRⁱ	Q61545
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Repeatⁱ	8 – 16	1	9
Repeatⁱ	17 – 27	2Add BLAST	11
Repeatⁱ	28 – 34	3	7
Repeatⁱ	35 – 42	4	8
Repeatⁱ	43 – 50	5	8
Repeatⁱ	51 – 59	6	9
Repeatⁱ	60 – 68	7	9
Repeatⁱ	69 – 75	8	7
Repeatⁱ	76 – 84	9	9
Repeatⁱ	85 – 91	10	7
Repeatⁱ	92 – 110	11Add BLAST	19
Repeatⁱ	111 – 116	12	6
Repeatⁱ	117 – 125	13	9
Repeatⁱ	126 – 156	14Add BLAST	31
Repeatⁱ	157 – 163	15	7
Repeatⁱ	164 – 170	16	7
Repeatⁱ	171 – 177	17	7
Repeatⁱ	178 – 188	18Add BLAST	11
Repeatⁱ	189 – 193	19	5
Repeatⁱ	194 – 201	20	8
Repeatⁱ	202 – 206	21	5
Repeatⁱ	207 – 212	22	6
Repeatⁱ	213 – 218	23	6
Repeatⁱ	219 – 224	24	6
Repeatⁱ	225 – 230	25	6
Repeatⁱ	231 – 238	26	8
Repeatⁱ	239 – 245	27	7
Repeatⁱ	246 – 252	28	7
Repeatⁱ	253 – 259	29	7
Domainⁱ	256 – 285	IQAdd BLAST	30
Repeatⁱ	260 – 276	30Add BLAST	17
Repeatⁱ	277 – 285	31	9
Domainⁱ	360 – 446	RRMPROSITE-ProRule annotationAdd BLAST	87

Region

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Regionⁱ	1 – 285	EAD (Gln/Pro/Thr-rich)Add BLAST		285
Regionⁱ	8 – 285	31 X approximate tandem repeatsAdd BLAST		278

Motif

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Motifⁱ	638 – 655	Nuclear localization signalBy similarityAdd BLAST		18

Compositional bias

Feature key	Position(s)	DescriptionActions	Length
Compositional biasⁱ	300 – 339	Arg/Gly/Pro-richAdd BLAST	40
Compositional biasⁱ	453 – 512	Arg/Gly/Pro-richAdd BLAST	60
Compositional biasⁱ	558 – 639	Arg/Gly/Pro-richAdd BLAST	82

Sequence similaritiesⁱ

Belongs to the RRM TET family.Curated

Zinc finger

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Zinc fingerⁱ	517 – 548	RanBP2-typePROSITE-ProRule annotationAdd BLAST		32

Keywords - Domainⁱ

Repeat, Zinc-finger

Phylogenomic databases

eggNOGⁱ	KOG1995 Eukaryota ENOG4111Q2F LUCA
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00530000063105
HOVERGENⁱ	HBG000970
InParanoidⁱ	Q61545
KEGG Orthology (KO) More...KOⁱ	K13209
TreeFamⁱ	TF322599

Family and domain databases

Conserved Domains Database More...CDDⁱ	cd12533 RRM_EWS, 1 hit
Gene3Dⁱ	3.30.70.330, 1 hit
InterProⁱ	View protein in InterPro IPR034869 EWS_RRM IPR033109 EWSR1 IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR000504 RRM_dom IPR034870 TET_fam IPR001876 Znf_RanBP2 IPR036443 Znf_RanBP2_sf
PANTHERⁱ	PTHR23238 PTHR23238, 1 hit PTHR23238:SF3 PTHR23238:SF3, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00076 RRM_1, 1 hit PF00641 zf-RanBP, 1 hit
SMARTⁱ	View protein in SMART SM00360 RRM, 1 hit SM00547 ZnF_RBZ, 1 hit
SUPFAMⁱ	SSF54928 SSF54928, 1 hit SSF90209 SSF90209, 1 hit
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 1 hit PS01358 ZF_RANBP2_1, 1 hit PS50199 ZF_RANBP2_2, 1 hit

Sequence (1+)ⁱ

Sequence statusⁱ: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show all Align All

Q61545-1 [UniParc]FASTA Add to basket

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        10         20         30         40         50
MASTDYSTYS QAAAQQGYSA YTAQPTQGYA QTTQAYGQQS YGTYGQPTDV 
        60         70         80         90        100
SYTQAQTTAT YGQTAYATSY GQPPTGYSTP TAPQAYSQPV QGYGTGTYDS 
       110        120        130        140        150
TTATVTTTQA SYAAQTAYGT QPAYPTYGQQ PTATAPTRPQ DGNKPAETSQ 
       160        170        180        190        200
PQSSTGGYNQ PSLGYGQSNY SYPQVPGSYP MQPVTAPPSY PPTSYSSSQP 
       210        220        230        240        250
TSYDQSSYSQ QNTYGQPSSY GQQSSYGQQS SYGQQPPTSY PPQTGSYSQA 
       260        270        280        290        300
PSQYSQQSSS YGQQSSFRQD HPSSMGVYGQ ESGGFSGPGE NRSLSGPDNR 
       310        320        330        340        350
GRGRGGFDRG GMSRGGRGGG RGGLGAGERG GFNKPGGPMD EGPDLDLGLP 
       360        370        380        390        400
IDPDEDSDNS AIYVQGLNDN VTLDDLADFF KQCGVVKMNK RTGQPMIHIY 
       410        420        430        440        450
LDKETGKPKG DATVSYEDPP TAKAAVEWFD GKDFQGSKLK VSLARKKPPM 
       460        470        480        490        500
NSMRGGMPPR EGRGMPPPLR GGPGGPGGPG GPMGRMGGRG GDRGGFPPRG 
       510        520        530        540        550
PRGSRGNPSG GGNVQHRAGD WQCPNPGCGN QNFAWRTECN QCKAPKPEGF 
       560        570        580        590        600
LPPPFPPPGG DRGRGGPGGM RGGRGGLMDR GGPGGMFRGG RGGDRGGFRG 
       610        620        630        640        650
GRGMDRGGFG GGRRGGPGGP PGPLMEQMGG RRGGRGGPGK MDKGEHRQER 

RDRPY

Length:655

Mass (Da):68,462

Last modified:July 27, 2011 - v2

Checksum:ⁱ10C7F06A921668F3

Computationally mapped potential isoform sequencesⁱ

There are 4 potential isoforms mapped to this entry.BLAST Align Show all Add to basket

Entry	Entry name	Protein names	Gene names	Length	Annotation

Q5SUS9	Q5SUS9_MOUSE	RNA-binding protein EWS RNA-binding protein EWS	Ewsr1	661	Annotation score:
Q5SUT0	Q5SUT0_MOUSE	RNA-binding protein EWS RNA-binding protein EWS	Ewsr1	618	Annotation score:
Q5SUS8	Q5SUS8_MOUSE	RNA-binding protein EWS RNA-binding protein EWS	Ewsr1	354	Annotation score:
Q8BQU4	Q8BQU4_MOUSE	RNA-binding protein EWS RNA-binding protein EWS	Ewsr1	113	Annotation score:

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Sequence conflictⁱ	97	T → A in CAA55815 (PubMed:7829090).Curated		1
Sequence conflictⁱ	116	T → S in CAA55815 (PubMed:7829090).Curated		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X79233 mRNA Translation: CAA55815.1 AK019460 mRNA Translation: BAB31732.1 AK151625 mRNA Translation: BAE30560.1 AL645845 Genomic DNA Translation: CAI25231.1 CH466574 Genomic DNA Translation: EDL40519.1
The Consensus CDS (CCDS) project More...CCDSⁱ	CCDS24396.1
PIRⁱ	A55726
NCBI Reference Sequences More...RefSeqⁱ	NP_031994.2, NM_007968.3
UniGeneⁱ	Mm.142822

Genome annotation databases

Ensemblⁱ	ENSMUST00000079949; ENSMUSP00000078867; ENSMUSG00000009079
GeneIDⁱ	14030
KEGGⁱ	mmu:14030
UCSC genome browser More...UCSCⁱ	uc007hvw.2 mouse

Similar proteinsⁱ

90% Identity
50% Identity

Protein	Similar proteins		Species	Score	Length	Source
Q61545	RNA-binding protein EWS	)	HUMAN		656	UniRef90_Q01844
Uncharacterized protein		RABIT		751
RNA-binding protein EWS isoform X1		DELLE		718
Uncharacterized protein (Fragment)		NEOLE		693
Uncharacterized protein		CANLF		671
+374

Protein	Similar proteins		Species	Score	Length	Source
Q61545	RNA-binding protein EWS	)	HUMAN		656	UniRef50_Q01844
Uncharacterized protein		RABIT		751
RNA-binding protein EWS isoform X1		DELLE		718
Uncharacterized protein (Fragment)		NEOLE		693
Uncharacterized protein		CANLF		671
+434

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	X79233 mRNA Translation: CAA55815.1 AK019460 mRNA Translation: BAB31732.1 AK151625 mRNA Translation: BAE30560.1 AL645845 Genomic DNA Translation: CAI25231.1 CH466574 Genomic DNA Translation: EDL40519.1
CCDSⁱ	CCDS24396.1
PIRⁱ	A55726
RefSeqⁱ	NP_031994.2, NM_007968.3
UniGeneⁱ	Mm.142822

3D structure databases

ProteinModelPortalⁱ	Q61545
SMRⁱ	Q61545
ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

BioGridⁱ	199551, 73 interactors
IntActⁱ	Q61545, 17 interactors
MINTⁱ	Q61545
STRINGⁱ	10090.ENSMUSP00000078867

PTM databases

iPTMnetⁱ	Q61545
PhosphoSitePlusⁱ	Q61545
SwissPalmⁱ	Q61545

Proteomic databases

EPDⁱ	Q61545
MaxQBⁱ	Q61545
PaxDbⁱ	Q61545
PRIDEⁱ	Q61545

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000079949; ENSMUSP00000078867; ENSMUSG00000009079
GeneIDⁱ	14030
KEGGⁱ	mmu:14030
UCSCⁱ	uc007hvw.2 mouse

Organism-specific databases

CTDⁱ	2130
MGIⁱ	MGI:99960 Ewsr1

Phylogenomic databases

eggNOGⁱ	KOG1995 Eukaryota ENOG4111Q2F LUCA
GeneTreeⁱ	ENSGT00530000063105
HOVERGENⁱ	HBG000970
InParanoidⁱ	Q61545
KOⁱ	K13209
TreeFamⁱ	TF322599

Miscellaneous databases

Protein Ontology More...PROⁱ	PR:Q61545
SOURCEⁱ	Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000009079 Expressed in 301 organ(s), highest expression level in urinary bladder
CleanExⁱ	MM_EWSR1
ExpressionAtlasⁱ	Q61545 baseline and differential
Genevisibleⁱ	Q61545 MM

Family and domain databases

CDDⁱ	cd12533 RRM_EWS, 1 hit
Gene3Dⁱ	3.30.70.330, 1 hit
InterProⁱ	View protein in InterPro IPR034869 EWS_RRM IPR033109 EWSR1 IPR012677 Nucleotide-bd_a/b_plait_sf IPR035979 RBD_domain_sf IPR000504 RRM_dom IPR034870 TET_fam IPR001876 Znf_RanBP2 IPR036443 Znf_RanBP2_sf
PANTHERⁱ	PTHR23238 PTHR23238, 1 hit PTHR23238:SF3 PTHR23238:SF3, 1 hit
Pfamⁱ	View protein in Pfam PF00076 RRM_1, 1 hit PF00641 zf-RanBP, 1 hit
SMARTⁱ	View protein in SMART SM00360 RRM, 1 hit SM00547 ZnF_RBZ, 1 hit
SUPFAMⁱ	SSF54928 SSF54928, 1 hit SSF90209 SSF90209, 1 hit
PROSITEⁱ	View protein in PROSITE PS50102 RRM, 1 hit PS01358 ZF_RANBP2_1, 1 hit PS50199 ZF_RANBP2_2, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	EWS_MOUSE
Accessionⁱ	Q61545Primary (citable) accession number: Q61545 Secondary accession number(s): Q9D2P0
Entry historyⁱ	Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
	Last sequence update:	July 27, 2011
	Last modified:	September 12, 2018
	This is version 171 of the entry and version 2 of the sequence. See complete history.
Entry statusⁱ	Reviewed (UniProtKB/Swiss-Prot)
Annotation program	Chordata Protein Annotation Program

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Reference proteome

Documents

SIMILARITY comments
Index of protein domains and families
MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q61545 (EWS_MOUSE)

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RNA-binding protein EWS

Ewsr1

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Miscellaneous

Regions

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Nucleus

Plasma membrane

Other locations

Nucleus

Plasma Membrane

Other locations

Keywords - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Amino acid modifications

Keywords - PTMi

Proteomic databases

PTM databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Region

Motif

Compositional bias

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Zinc finger

Keywords - Domaini

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

PTM databases

Proteomic databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Documents

UniProt is an ELIXIR core data resource

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Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Keywords - Cellular componentⁱ

PTM / Processingⁱ

Keywords - PTMⁱ

Expressionⁱ

Interactionⁱ

GO - Molecular functionⁱ

Structureⁱ

Family & Domainsⁱ

Sequence similaritiesⁱ

Keywords - Domainⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ

Keywords - Technical termⁱ