UniProtKB - Q61466 (SMRD1_MOUSE)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1
Smarcd1
Functioni
GO - Molecular functioni
- chromatin binding Source: MGI
- molecular adaptor activity Source: MGI
- signaling receptor binding Source: MGI
GO - Biological processi
- cellular response to fatty acid Source: Ensembl
- chromatin-mediated maintenance of transcription Source: MGI
- chromatin remodeling Source: MGI
- nervous system development Source: UniProtKB-KW
- nucleosome disassembly Source: MGI
- positive regulation of transcription by RNA polymerase II Source: GO_Central
- regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | Chromatin regulator |
Biological process | Neurogenesis |
Enzyme and pathway databases
Reactomei | R-MMU-3214858, RMTs methylate histone arginines R-MMU-8939243, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known |
Names & Taxonomyi
Protein namesi | Recommended name: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1Alternative name(s): 60 kDa BRG-1/Brm-associated factor subunit A BRG1-associated factor 60A Short name: BAF60A Protein D15KZ1 SWI/SNF complex 60 kDa subunit |
Gene namesi | Name:Smarcd1 Synonyms:Baf60a, D15Kz1 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1933623, Smarcd1 |
Subcellular locationi
Nucleus
- Nucleus Curated
Nucleus
- nBAF complex Source: UniProtKB
- npBAF complex Source: UniProtKB
- nucleoplasm Source: MGI
- nucleus Source: MGI
- SWI/SNF complex Source: UniProtKB
Other locations
- intracellular membrane-bounded organelle Source: MGI
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000071984 | 1 – 515 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1Add BLAST | 515 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 68 | Asymmetric dimethylarginineBy similarity | 1 | |
Modified residuei | 88 | Asymmetric dimethylarginineCombined sources | 1 | |
Cross-linki | 101 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity | ||
Modified residuei | 203 | PhosphothreonineBy similarity | 1 | |
Modified residuei | 223 | N6-acetyllysineCombined sources | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Methylation, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q61466 |
PaxDbi | Q61466 |
PeptideAtlasi | Q61466 |
PRIDEi | Q61466 |
PTM databases
iPTMneti | Q61466 |
PhosphoSitePlusi | Q61466 |
Expressioni
Tissue specificityi
Developmental stagei
Gene expression databases
Bgeei | ENSMUSG00000023018, Expressed in cortical plate and 269 other tissues |
ExpressionAtlasi | Q61466, baseline and differential |
Genevisiblei | Q61466, MM |
Interactioni
Subunit structurei
Component of the multiprotein chromatin-remodeling complexes SWI/SNF: SWI/SNF-A (BAF), SWI/SNF-B (PBAF) and related complexes. The canonical complex contains a catalytic subunit (either SMARCA4/BRG1/BAF190A or SMARCA2/BRM/BAF190B), and at least SMARCE1, ACTL6A/BAF53, SMARCC1/BAF155, SMARCC2/BAF170, and SMARCB1/SNF5/BAF47. Other subunits specific to each of the complexes may also be present permitting several possible combinations developmentally and tissue specific (PubMed:8804307, PubMed:8895581).
Component of the BAF complex, which includes at least actin (ACTB), ARID1A/BAF250A, ARID1B/BAF250B, SMARCA2/BRM, SMARCA4/BRG1/BAF190A, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C (By similarity). In muscle cells, the BAF complex also contains DPF3.
Component of neural progenitors-specific chromatin remodeling complex (npBAF complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, PHF10/BAF45A, ACTL6A/BAF53A and actin.
Component of neuron-specific chromatin remodeling complex (nBAF complex) composed of at least, ARID1A/BAF250A or ARID1B/BAF250B, SMARCD1/BAF60A, SMARCD3/BAF60C, SMARCA2/BRM/BAF190B, SMARCA4/BRG1/BAF190A, SMARCB1/BAF47, SMARCC1/BAF155, SMARCE1/BAF57, SMARCC2/BAF170, DPF1/BAF45B, DPF3/BAF45C, ACTL6B/BAF53B and actin (PubMed:17640523).
Component of the SWI/SNF-B (PBAF) chromatin remodeling complex, at least composed of SMARCA4/BRG1, SMARCB1/BAF47/SNF5, ACTL6A/BAF53A or ACTL6B/BAF53B, SMARCE1/BAF57, SMARCD1/BAF60A, SMARCD2/BAF60B, perhaps SMARCD3/BAF60C, SMARCC1/BAF155, SMARCC2/BAF170, PBRM1/BAF180, ARID2/BAF200 and actin (ACTB) (By similarity).
Component of SWI/SNF (GBAF) subcomplex, which includes at least BICRA or BICRAL (mutually exclusive), BRD9, SS18, SMARCA2/BRM, SMARCA4/BRG1/BAF190A, ACTL6A/BAF53, SMARCC1/BAF155, and SMARCD1/BAF60A (PubMed:29374058). Specifically interacts with the VDR heterodimer complex.
Interacts with ESR1, NR3C1, NR1H4, PGR, SMARCA4, SMARCC1 and SMARCC2 (By similarity).
Interacts with DPF2.
By similarity4 PublicationsBinary interactionsi
Hide detailsQ61466
With | #Exp. | IntAct |
---|---|---|
Akirin2 [B1AXD8] | 2 | EBI-371529,EBI-10107866 |
Smarcc1 [P97496] | 3 | EBI-371529,EBI-648047 |
Tbx1 [P70323] | 3 | EBI-371529,EBI-13635846 |
Tp53 [P02340] | 4 | EBI-371529,EBI-474016 |
GO - Molecular functioni
- signaling receptor binding Source: MGI
Protein-protein interaction databases
BioGRIDi | 219977, 25 interactors |
ComplexPortali | CPX-1232, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA2 variant CPX-1233, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA4 variant CPX-1234, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA2 variant CPX-1235, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA4 variant CPX-1236, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA2 variant CPX-1237, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA4 variant CPX-1238, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA2 variant CPX-1239, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA4 variant CPX-1240, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA2 variant CPX-1241, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA4 variant CPX-1242, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA2 variant CPX-1243, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA4 variant CPX-1244, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA2 variant CPX-1245, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA4 variant CPX-1246, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA2 variant CPX-1247, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA4 variant CPX-1248, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A variant CPX-1250, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B variant CPX-1251, Embryonic stem cell-specific SWI/SNF ATP-dependent chromatin remodeling complex CPX-1252, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA2 variant CPX-1253, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA4 variant CPX-1254, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA2 variant CPX-1255, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA4 variant CPX-1256, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA2 variant CPX-1257, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA4 variant CPX-1258, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA2 variant CPX-1259, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA4 variant CPX-4202, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRA-SMARCA2 variant CPX-4204, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRAL-SMARCA2 variant CPX-4221, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRA-SMARCA4 variant CPX-4222, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRAL-SMARCA4 variant CPX-4227, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRA-SMARCA2 variant CPX-4228, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRAL-SMARCA2 variant CPX-4229, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRA-SMARCA4 variant CPX-4230, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRAL-SMARCA4 variant |
CORUMi | Q61466 |
DIPi | DIP-33019N |
IntActi | Q61466, 14 interactors |
MINTi | Q61466 |
STRINGi | 10090.ENSMUSP00000023759 |
Miscellaneous databases
RNActi | Q61466, protein |
Structurei
Secondary structure
3D structure databases
SMRi | Q61466 |
ModBasei | Search... |
PDBe-KBi | Search... |
Miscellaneous databases
EvolutionaryTracei | Q61466 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 290 – 367 | SWIB/MDM2PROSITE-ProRule annotationAdd BLAST | 78 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 43 – 167 | Interaction with ESR1, NR1H4, NR3C1, PGR and SMARCA4By similarityAdd BLAST | 125 | |
Regioni | 168 – 474 | Interaction with SMARCC1 and SMARCC2By similarityAdd BLAST | 307 | |
Regioni | 180 – 515 | Necessary for GR/NR3C1-mediated remodeling and transcription from chromatin; required for GR/NR3C1 interaction with the BRG1/SMARCA4 complex in vivoBy similarityAdd BLAST | 336 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 412 – 440 | Sequence analysisAdd BLAST | 29 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 124 – 127 | Poly-Lys | 4 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilPhylogenomic databases
eggNOGi | KOG2570, Eukaryota |
GeneTreei | ENSGT00940000156629 |
HOGENOMi | CLU_023529_0_1_1 |
InParanoidi | Q61466 |
OMAi | MNITINL |
OrthoDBi | 1027566at2759 |
PhylomeDBi | Q61466 |
TreeFami | TF106486 |
Family and domain databases
Gene3Di | 1.10.245.10, 1 hit |
InterProi | View protein in InterPro IPR038041, SMARCD1 IPR019835, SWIB_domain IPR036885, SWIB_MDM2_dom_sf IPR003121, SWIB_MDM2_domain |
PANTHERi | PTHR13844:SF1, PTHR13844:SF1, 1 hit |
Pfami | View protein in Pfam PF02201, SWIB, 1 hit |
SMARTi | View protein in SMART SM00151, SWIB, 1 hit |
SUPFAMi | SSF47592, SSF47592, 1 hit |
PROSITEi | View protein in PROSITE PS51925, SWIB_MDM2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MAARAGFQSV APSGGAGASG GAGVAAALGP GGTPGPPVRM GPAPGQGLYR
60 70 80 90 100
SPMPGAAYPR PGMLPGSRMT PQGPSMGPPG YGGNPSVRPG LAQSGMDQSR
110 120 130 140 150
KRPAPQQIQQ VQQQAVQNRN HNAKKKKMAD KILPQRIREL VPESQAYMDL
160 170 180 190 200
LAFERKLDQT IMRKRLDIQE ALKRPIKQKR KLRIFISNTF NPAKSDAEDG
210 220 230 240 250
EGTVASWELR VEGRLLEDAA LSKYDATKQK RKFSSFFKSL VIELDKDLYG
260 270 280 290 300
PDNHLVEWHR TATTQETDGF QVKRPGDVNV RCTVLLMLDY QPPQFKLDPR
310 320 330 340 350
LARLLGIHTQ TRPVIIQALW QYIKTHKLQD PHEREFVLCD KYLQQIFESQ
360 370 380 390 400
RMKFSEIPQR LHALLMPPEP IIINHVISVD PNDQKKTACY DIDVEVDDTL
410 420 430 440 450
KTQMNSFLLS TASQQEIATL DNKIHETIET INQLKTQREF MLSFARDPQG
460 470 480 490 500
FINDWLQSQC RDLKTMTDVV GNPEEERRAE FYFQPWAQEA VCRYFYSKVQ
510
QRRQELEQAL GIRNT
Computationally mapped potential isoform sequencesi
There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A2R8VKP3 | A0A2R8VKP3_MOUSE | SWI/SNF-related matrix-associated a... | Smarcd1 | 474 | Annotation score: | ||
A0A2R8VHB7 | A0A2R8VHB7_MOUSE | SWI/SNF-related matrix-associated a... | Smarcd1 | 95 | Annotation score: | ||
A0A2R8VI06 | A0A2R8VI06_MOUSE | SWI/SNF-related matrix-associated a... | Smarcd1 | 175 | Annotation score: | ||
A0A2R8VI28 | A0A2R8VI28_MOUSE | SWI/SNF-related matrix-associated a... | Smarcd1 | 98 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 15 | G → A in AAA53377 (PubMed:2725507).Curated | 1 | |
Sequence conflicti | 15 | G → A in AAC52794 (PubMed:8804307).Curated | 1 | |
Sequence conflicti | 215 | L → I in BAC35856 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 218 | D → E in BAC35856 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 449 | Q → S in AAA53377 (PubMed:2725507).Curated | 1 | |
Sequence conflicti | 449 | Q → S in AAC52794 (PubMed:8804307).Curated | 1 | |
Sequence conflicti | 462 | D → G in AAA53377 (PubMed:2725507).Curated | 1 | |
Sequence conflicti | 462 | D → G in AAC52794 (PubMed:8804307).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC026783 mRNA Translation: AAH26783.3 Different initiation. BC059921 mRNA No translation available. M25773 mRNA Translation: AAA53377.1 Sequence problems. U66620 mRNA Translation: AAC52794.1 Sequence problems. AK075611 mRNA Translation: BAC35856.1 |
CCDSi | CCDS37204.1 |
PIRi | A30222 |
RefSeqi | NP_114030.2, NM_031842.2 |
Genome annotation databases
Ensembli | ENSMUST00000023759; ENSMUSP00000023759; ENSMUSG00000023018 |
GeneIDi | 83797 |
KEGGi | mmu:83797 |
UCSCi | uc007xqb.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BC026783 mRNA Translation: AAH26783.3 Different initiation. BC059921 mRNA No translation available. M25773 mRNA Translation: AAA53377.1 Sequence problems. U66620 mRNA Translation: AAC52794.1 Sequence problems. AK075611 mRNA Translation: BAC35856.1 |
CCDSi | CCDS37204.1 |
PIRi | A30222 |
RefSeqi | NP_114030.2, NM_031842.2 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
1UHR | NMR | - | A | 291-370 | [»] | |
SMRi | Q61466 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 219977, 25 interactors |
ComplexPortali | CPX-1232, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA2 variant CPX-1233, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA4 variant CPX-1234, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA2 variant CPX-1235, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA4 variant CPX-1236, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA2 variant CPX-1237, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA4 variant CPX-1238, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA2 variant CPX-1239, SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA4 variant CPX-1240, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA2 variant CPX-1241, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1A-SMARCA4 variant CPX-1242, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA2 variant CPX-1243, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A-ARID1B-SMARCA4 variant CPX-1244, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA2 variant CPX-1245, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1A-SMARCA4 variant CPX-1246, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA2 variant CPX-1247, Muscle cell-specific SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B-ARID1B-SMARCA4 variant CPX-1248, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6A variant CPX-1250, Polybromo-associated SWI/SNF ATP-dependent chromatin remodeling complex, ACTL6B variant CPX-1251, Embryonic stem cell-specific SWI/SNF ATP-dependent chromatin remodeling complex CPX-1252, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA2 variant CPX-1253, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA4 variant CPX-1254, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA2 variant CPX-1255, Neural progenitor-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA4 variant CPX-1256, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA2 variant CPX-1257, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1A-SMARCA4 variant CPX-1258, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA2 variant CPX-1259, Neuron-specific SWI/SNF ATP-dependent chromatin remodeling complex, ARID1B-SMARCA4 variant CPX-4202, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRA-SMARCA2 variant CPX-4204, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRAL-SMARCA2 variant CPX-4221, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRA-SMARCA4 variant CPX-4222, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6A-BICRAL-SMARCA4 variant CPX-4227, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRA-SMARCA2 variant CPX-4228, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRAL-SMARCA2 variant CPX-4229, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRA-SMARCA4 variant CPX-4230, GBAF (SWI/SNF) ATP-dependent chromatin remodeling complex, ACTL6B-BICRAL-SMARCA4 variant |
CORUMi | Q61466 |
DIPi | DIP-33019N |
IntActi | Q61466, 14 interactors |
MINTi | Q61466 |
STRINGi | 10090.ENSMUSP00000023759 |
PTM databases
iPTMneti | Q61466 |
PhosphoSitePlusi | Q61466 |
Proteomic databases
EPDi | Q61466 |
PaxDbi | Q61466 |
PeptideAtlasi | Q61466 |
PRIDEi | Q61466 |
Protocols and materials databases
Antibodypediai | 1319, 261 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000023759; ENSMUSP00000023759; ENSMUSG00000023018 |
GeneIDi | 83797 |
KEGGi | mmu:83797 |
UCSCi | uc007xqb.1, mouse |
Organism-specific databases
CTDi | 6602 |
MGIi | MGI:1933623, Smarcd1 |
Phylogenomic databases
eggNOGi | KOG2570, Eukaryota |
GeneTreei | ENSGT00940000156629 |
HOGENOMi | CLU_023529_0_1_1 |
InParanoidi | Q61466 |
OMAi | MNITINL |
OrthoDBi | 1027566at2759 |
PhylomeDBi | Q61466 |
TreeFami | TF106486 |
Enzyme and pathway databases
Reactomei | R-MMU-3214858, RMTs methylate histone arginines R-MMU-8939243, RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known |
Miscellaneous databases
BioGRID-ORCSi | 83797, 5 hits in 21 CRISPR screens |
ChiTaRSi | Smarcd1, mouse |
EvolutionaryTracei | Q61466 |
PROi | PR:Q61466 |
RNActi | Q61466, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000023018, Expressed in cortical plate and 269 other tissues |
ExpressionAtlasi | Q61466, baseline and differential |
Genevisiblei | Q61466, MM |
Family and domain databases
Gene3Di | 1.10.245.10, 1 hit |
InterProi | View protein in InterPro IPR038041, SMARCD1 IPR019835, SWIB_domain IPR036885, SWIB_MDM2_dom_sf IPR003121, SWIB_MDM2_domain |
PANTHERi | PTHR13844:SF1, PTHR13844:SF1, 1 hit |
Pfami | View protein in Pfam PF02201, SWIB, 1 hit |
SMARTi | View protein in SMART SM00151, SWIB, 1 hit |
SUPFAMi | SSF47592, SSF47592, 1 hit |
PROSITEi | View protein in PROSITE PS51925, SWIB_MDM2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | SMRD1_MOUSE | |
Accessioni | Q61466Primary (citable) accession number: Q61466 Secondary accession number(s): P70384, Q8R0I7 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 |
Last sequence update: | May 26, 2009 | |
Last modified: | February 10, 2021 | |
This is version 167 of the entry and version 3 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
3D-structure, Direct protein sequencing, Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families