Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

B-cell receptor-associated protein 29

Gene

Bcap29

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).By similarity

GO - Biological processi

Keywordsi

Biological processApoptosis, ER-Golgi transport, Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
B-cell receptor-associated protein 29
Short name:
BCR-associated protein 29
Short name:
Bap29
Gene namesi
Name:Bcap29
Synonyms:Bap29
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:101917 Bcap29

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 6LumenalSequence analysis6
Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Topological domaini28 – 43CytoplasmicSequence analysisAdd BLAST16
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Topological domaini65 – 103LumenalSequence analysisAdd BLAST39
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Topological domaini125 – 240CytoplasmicSequence analysisAdd BLAST116

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001428891 – 240B-cell receptor-associated protein 29Add BLAST240

Proteomic databases

EPDiQ61334
MaxQBiQ61334
PaxDbiQ61334
PRIDEiQ61334
TopDownProteomicsiQ61334

PTM databases

iPTMnetiQ61334
PhosphoSitePlusiQ61334

Expressioni

Tissue specificityi

Highly expressed in brain and testis; detected at lower levels in thymus, spleen, liver, lung and bone marrow.

Gene expression databases

BgeeiENSMUSG00000020650 Expressed in 277 organ(s), highest expression level in testis
CleanExiMM_BCAP29
ExpressionAtlasiQ61334 baseline and differential
GenevisibleiQ61334 MM

Interactioni

Subunit structurei

Homodimer and heterodimer with BCAP31. Binds CASP8 as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1. Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II (By similarity).By similarity

Protein-protein interaction databases

IntActiQ61334, 1 interactor
STRINGi10090.ENSMUSP00000020979

Structurei

3D structure databases

ProteinModelPortaliQ61334
SMRiQ61334
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili166 – 232By similarityAdd BLAST67

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi237 – 240Di-lysine motif4

Sequence similaritiesi

Belongs to the BCAP29/BCAP31 family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG1962 Eukaryota
COG5374 LUCA
GeneTreeiENSGT00390000011863
HOGENOMiHOG000204790
HOVERGENiHBG050661
InParanoidiQ61334
OMAiAQNDVMT
OrthoDBiEOG091G0MHN
PhylomeDBiQ61334
TreeFamiTF315310

Family and domain databases

InterProiView protein in InterPro
IPR008417 BAP29/BAP31
PANTHERiPTHR12701 PTHR12701, 1 hit
PfamiView protein in Pfam
PF05529 Bap31, 1 hit

Sequencei

Sequence statusi: Complete.

Q61334-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIQWAAVAS FLYAEIGLIL LFCLPFIPPQ RWQKIFSFSV WGKIASFWNK
60 70 80 90 100
AFLTIIILLI ILFLDAVREV RKYSSTNVVE KNSAIRPSAF EHTQMKLFRS
110 120 130 140 150
QRNLYISGFS LFFWLVLRRL VTLITQLAKE IANKGVLKIQ AENTNKAAKK
160 170 180 190 200
FMEENEKLKL GLRNDNAEEH LLEAENKKLI ESKENLKTEL KKASDALLKA
210 220 230 240
QNDVMTMKIQ SERLSKEYDR LLKEHSELQN RLEKEKKKGL
Length:240
Mass (Da):27,964
Last modified:November 1, 1996 - v1
Checksum:i6592492403C4AF1D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78684 mRNA Translation: CAA55351.1
BC003303 mRNA Translation: AAH03303.1
BC021661 mRNA Translation: AAH21661.1
CCDSiCCDS25864.1
PIRiS46997
RefSeqiNP_001157562.1, NM_001164090.1
NP_031556.1, NM_007530.3
UniGeneiMm.242379

Genome annotation databases

EnsembliENSMUST00000020979; ENSMUSP00000020979; ENSMUSG00000020650
ENSMUST00000177962; ENSMUSP00000137260; ENSMUSG00000020650
GeneIDi12033
KEGGimmu:12033
UCSCiuc007nhp.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78684 mRNA Translation: CAA55351.1
BC003303 mRNA Translation: AAH03303.1
BC021661 mRNA Translation: AAH21661.1
CCDSiCCDS25864.1
PIRiS46997
RefSeqiNP_001157562.1, NM_001164090.1
NP_031556.1, NM_007530.3
UniGeneiMm.242379

3D structure databases

ProteinModelPortaliQ61334
SMRiQ61334
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ61334, 1 interactor
STRINGi10090.ENSMUSP00000020979

PTM databases

iPTMnetiQ61334
PhosphoSitePlusiQ61334

Proteomic databases

EPDiQ61334
MaxQBiQ61334
PaxDbiQ61334
PRIDEiQ61334
TopDownProteomicsiQ61334

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000020979; ENSMUSP00000020979; ENSMUSG00000020650
ENSMUST00000177962; ENSMUSP00000137260; ENSMUSG00000020650
GeneIDi12033
KEGGimmu:12033
UCSCiuc007nhp.1 mouse

Organism-specific databases

CTDi55973
MGIiMGI:101917 Bcap29

Phylogenomic databases

eggNOGiKOG1962 Eukaryota
COG5374 LUCA
GeneTreeiENSGT00390000011863
HOGENOMiHOG000204790
HOVERGENiHBG050661
InParanoidiQ61334
OMAiAQNDVMT
OrthoDBiEOG091G0MHN
PhylomeDBiQ61334
TreeFamiTF315310

Miscellaneous databases

PROiPR:Q61334
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020650 Expressed in 277 organ(s), highest expression level in testis
CleanExiMM_BCAP29
ExpressionAtlasiQ61334 baseline and differential
GenevisibleiQ61334 MM

Family and domain databases

InterProiView protein in InterPro
IPR008417 BAP29/BAP31
PANTHERiPTHR12701 PTHR12701, 1 hit
PfamiView protein in Pfam
PF05529 Bap31, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiBAP29_MOUSE
AccessioniPrimary (citable) accession number: Q61334
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: November 1, 1996
Last modified: November 7, 2018
This is version 131 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again