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Entry version 147 (23 Feb 2022)
Sequence version 1 (01 Nov 1996)
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Protein

B-cell receptor-associated protein 29

Gene

Bcap29

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May play a role in anterograde transport of membrane proteins from the endoplasmic reticulum to the Golgi. May be involved in CASP8-mediated apoptosis (By similarity).

By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processApoptosis, ER-Golgi transport, Protein transport, Transport

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
B-cell receptor-associated protein 29
Short name:
BCR-associated protein 29
Short name:
Bap29
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Bcap29
Synonyms:Bap29
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 12

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:101917, Bcap29

Eukaryotic Pathogen, Vector and Host Database Resources

More...
VEuPathDBi
HostDB:ENSMUSG00000020650

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 6LumenalSequence analysis6
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei7 – 27HelicalSequence analysisAdd BLAST21
Topological domaini28 – 43CytoplasmicSequence analysisAdd BLAST16
Transmembranei44 – 64HelicalSequence analysisAdd BLAST21
Topological domaini65 – 103LumenalSequence analysisAdd BLAST39
Transmembranei104 – 124HelicalSequence analysisAdd BLAST21
Topological domaini125 – 240CytoplasmicSequence analysisAdd BLAST116

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001428891 – 240B-cell receptor-associated protein 29Add BLAST240

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q61334

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q61334

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q61334

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q61334

PRoteomics IDEntifications database

More...
PRIDEi
Q61334

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
277161

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q61334

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q61334

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q61334

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in brain and testis; detected at lower levels in thymus, spleen, liver, lung and bone marrow.

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000020650, Expressed in spermatocyte and 302 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q61334, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q61334, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer and heterodimer with BCAP31. Binds CASP8 as a complex containing BCAP31, BCAP29, BCL2 and/or BCL2L1.

Interacts with VAMP3, VAMP1 and membrane IgD immunoglobulins. May interact with ACTG1 and non-muscle myosin II (By similarity).

By similarity

Protein-protein interaction databases

Protein interaction database and analysis system

More...
IntActi
Q61334, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000020979

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q61334, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q61334

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili166 – 232By similarityAdd BLAST67

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi237 – 240Di-lysine motif4

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the BCAP29/BCAP31 family.Curated

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG1962, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000011863

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_070975_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q61334

Identification of Orthologs from Complete Genome Data

More...
OMAi
FMARFWN

Database of Orthologous Groups

More...
OrthoDBi
1514108at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q61334

TreeFam database of animal gene trees

More...
TreeFami
TF315310

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008417, BAP29/BAP31
IPR040463, BAP29/BAP31_N
IPR041672, Bap31/Bap29_C

The PANTHER Classification System

More...
PANTHERi
PTHR12701, PTHR12701, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF05529, Bap31, 1 hit
PF18035, Bap31_Bap29_C, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q61334-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIQWAAVAS FLYAEIGLIL LFCLPFIPPQ RWQKIFSFSV WGKIASFWNK
60 70 80 90 100
AFLTIIILLI ILFLDAVREV RKYSSTNVVE KNSAIRPSAF EHTQMKLFRS
110 120 130 140 150
QRNLYISGFS LFFWLVLRRL VTLITQLAKE IANKGVLKIQ AENTNKAAKK
160 170 180 190 200
FMEENEKLKL GLRNDNAEEH LLEAENKKLI ESKENLKTEL KKASDALLKA
210 220 230 240
QNDVMTMKIQ SERLSKEYDR LLKEHSELQN RLEKEKKKGL
Length:240
Mass (Da):27,964
Last modified:November 1, 1996 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i6592492403C4AF1D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
X78684 mRNA Translation: CAA55351.1
BC003303 mRNA Translation: AAH03303.1
BC021661 mRNA Translation: AAH21661.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS25864.1

Protein sequence database of the Protein Information Resource

More...
PIRi
S46997

NCBI Reference Sequences

More...
RefSeqi
NP_001157562.1, NM_001164090.1
NP_031556.1, NM_007530.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000020979; ENSMUSP00000020979; ENSMUSG00000020650
ENSMUST00000177962; ENSMUSP00000137260; ENSMUSG00000020650

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
12033

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:12033

UCSC genome browser

More...
UCSCi
uc007nhp.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78684 mRNA Translation: CAA55351.1
BC003303 mRNA Translation: AAH03303.1
BC021661 mRNA Translation: AAH21661.1
CCDSiCCDS25864.1
PIRiS46997
RefSeqiNP_001157562.1, NM_001164090.1
NP_031556.1, NM_007530.3

3D structure databases

SMRiQ61334
ModBaseiSearch...

Protein-protein interaction databases

IntActiQ61334, 2 interactors
STRINGi10090.ENSMUSP00000020979

PTM databases

iPTMnetiQ61334
PhosphoSitePlusiQ61334

Proteomic databases

EPDiQ61334
jPOSTiQ61334
MaxQBiQ61334
PaxDbiQ61334
PRIDEiQ61334
ProteomicsDBi277161
TopDownProteomicsiQ61334

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
17207, 296 antibodies from 32 providers

The DNASU plasmid repository

More...
DNASUi
12033

Genome annotation databases

EnsembliENSMUST00000020979; ENSMUSP00000020979; ENSMUSG00000020650
ENSMUST00000177962; ENSMUSP00000137260; ENSMUSG00000020650
GeneIDi12033
KEGGimmu:12033
UCSCiuc007nhp.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
55973
MGIiMGI:101917, Bcap29
VEuPathDBiHostDB:ENSMUSG00000020650

Phylogenomic databases

eggNOGiKOG1962, Eukaryota
GeneTreeiENSGT00390000011863
HOGENOMiCLU_070975_1_0_1
InParanoidiQ61334
OMAiFMARFWN
OrthoDBi1514108at2759
PhylomeDBiQ61334
TreeFamiTF315310

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
12033, 0 hits in 64 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Bcap29, mouse

Protein Ontology

More...
PROi
PR:Q61334
RNActiQ61334, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000020650, Expressed in spermatocyte and 302 other tissues
ExpressionAtlasiQ61334, baseline and differential
GenevisibleiQ61334, MM

Family and domain databases

InterProiView protein in InterPro
IPR008417, BAP29/BAP31
IPR040463, BAP29/BAP31_N
IPR041672, Bap31/Bap29_C
PANTHERiPTHR12701, PTHR12701, 1 hit
PfamiView protein in Pfam
PF05529, Bap31, 1 hit
PF18035, Bap31_Bap29_C, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBAP29_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q61334
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 8, 2002
Last sequence update: November 1, 1996
Last modified: February 23, 2022
This is version 147 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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