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Entry version 173 (12 Aug 2020)
Sequence version 2 (31 Aug 2004)
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Protein

Contactin-2

Gene

Cntn2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

In conjunction with another transmembrane protein, CNTNAP2, contributes to the organization of axonal domains at nodes of Ranvier by maintaining voltage-gated potassium channels at the juxtaparanodal region.By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-376176, Signaling by ROBO receptors

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Contactin-2
Alternative name(s):
Axonal glycoprotein TAG-1
Axonin-1
Transient axonal glycoprotein 1
Short name:
TAX-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Cntn2
Synonyms:Tax
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:104518, Cntn2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 30By similarityAdd BLAST30
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001469731 – 1014Contactin-2Add BLAST984
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section describes a propeptide, which is a part of a protein that is cleaved during maturation or activation. Once cleaved, a propeptide generally has no independent biological function.<p><a href='/help/propep' target='_top'>More...</a></p>PropeptideiPRO_00000146981015 – 1040Removed in mature formSequence analysisAdd BLAST26

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi63 ↔ 113PROSITE-ProRule annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi78N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi157 ↔ 209PROSITE-ProRule annotation
Glycosylationi200N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi206N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi263 ↔ 308PROSITE-ProRule annotation
Disulfide bondi350 ↔ 397PROSITE-ProRule annotation
Glycosylationi463N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi479N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi500N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi527N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi777N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi832N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi920N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi942N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm%5Fprocessing%5Fsection">PTM / Processing</a> section specifies the position(s) and the type of covalently attached lipid group(s).<p><a href='/help/lipid' target='_top'>More...</a></p>Lipidationi1014GPI-anchor amidated serineSequence analysis1

Keywords - PTMi

Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q61330

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q61330

PeptideAtlas

More...
PeptideAtlasi
Q61330

PRoteomics IDEntifications database

More...
PRIDEi
Q61330

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2225, 6 N-Linked glycans (4 sites)

GlyGen: Computational and Informatics Resources for Glycoscience

More...
GlyGeni
Q61330, 11 sites

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q61330

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q61330

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000053024, Expressed in cortical plate and 162 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q61330, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
203974, 11 interactors

Protein interaction database and analysis system

More...
IntActi
Q61330, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000083707

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q61330, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

11040
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q61330

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini39 – 130Ig-like C2-type 1Add BLAST92
Domaini135 – 224Ig-like C2-type 2Add BLAST90
Domaini241 – 324Ig-like C2-type 3Add BLAST84
Domaini329 – 413Ig-like C2-type 4Add BLAST85
Domaini419 – 506Ig-like C2-type 5Add BLAST88
Domaini511 – 605Ig-like C2-type 6Add BLAST95
Domaini612 – 710Fibronectin type-III 1PROSITE-ProRule annotationAdd BLAST99
Domaini715 – 812Fibronectin type-III 2PROSITE-ProRule annotationAdd BLAST98
Domaini817 – 913Fibronectin type-III 3PROSITE-ProRule annotationAdd BLAST97
Domaini917 – 1008Fibronectin type-III 4PROSITE-ProRule annotationAdd BLAST92

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a short (usually not more than 20 amino acids) conserved sequence motif of biological significance.<p><a href='/help/motif' target='_top'>More...</a></p>Motifi796 – 798Cell attachment siteSequence analysis3

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi608 – 614Gly/Pro-rich7

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Keywords - Domaini

Immunoglobulin domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3513, Eukaryota

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159193

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_005756_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q61330

KEGG Orthology (KO)

More...
KOi
K06760

Identification of Orthologs from Complete Genome Data

More...
OMAi
HYVYRNE

Database of Orthologous Groups

More...
OrthoDBi
655902at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q61330

TreeFam database of animal gene trees

More...
TreeFami
TF351103

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 3 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 10 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR043204, Basigin-like
IPR032991, Contactin-2
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2

The PANTHER Classification System

More...
PANTHERi
PTHR10075, PTHR10075, 1 hit
PTHR10075:SF55, PTHR10075:SF55, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041, fn3, 3 hits
PF07679, I-set, 2 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060, FN3, 4 hits
SM00409, IG, 6 hits
SM00408, IGc2, 5 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 6 hits
SSF49265, SSF49265, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 4 hits
PS50835, IG_LIKE, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.Show allAlign All

Q61330-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGAPARKRAS LLLLLLATMA LVSSPGWSFS QGTPATFGPV FEEQPVGLLF
60 70 80 90 100
PEESAEDQVT LACRARASPP ATYRWKMNGT EMNLEPGSRH QLMGGNLVIM
110 120 130 140 150
SPTKAQDAGV YQCLASNPVG TVVSKEAVLR FGFLQEFSKE ERDPVKTHEG
160 170 180 190 200
WGVMLPCNPP AHYPGLSYRW LLNEFPNFIP TDGRHFVSQT TGNLYIARTN
210 220 230 240 250
ASDLGNYSCL ATSHLDFSTK SVFSKFAQLN LAAEDPRLFA PSIKARFPPE
260 270 280 290 300
TYALVGQQVT LECFAFGNPV PRIKWRKVDG SLSPQWGTAE PTLQIPSVSF
310 320 330 340 350
EDEGTYECEA ENSKGRDTVQ GRIIVQAQPE WLKVISDTEA DIGSNLRWGC
360 370 380 390 400
AAAGKPRPMV RWLRNGEPLA SQNRVEVLAG DLRFSKLNLE DSGMYQCVAE
410 420 430 440 450
NKHGTIYASA ELAVQALAPD FRQNPVRRLI PAARGGEISI PCQPRAAPKA
460 470 480 490 500
TILWSKGTEI LGNSTRVTVT LDGTLIIRNI SRSDEGKYTC FAENFMGKAN
510 520 530 540 550
STGILSVRDA TKITLAPSSA DINVGDNLTL QCHASHDPTM DLTFTWTLDD
560 570 580 590 600
FPVDFDKPGG HYRRASVKET IGDLTILNAQ LRHGGTYTCM AQTVVDGASK
610 620 630 640 650
EATVLVRGPP GPPGGVVVRD IGDTTVQLSW SRGFDNHSPI AKYTLQARTP
660 670 680 690 700
PSGKWKQVRT NPVNIEGNAE TAQVLGLMPW MDYEFRVSAS NILGTGEPSG
710 720 730 740 750
PSSRIRTKEA VPSVAPSGLS GGGGAPGELT INWTPMSREY QNGDGFGYLL
760 770 780 790 800
SFRRQGSSSW QTARVPGADT QYFVYSNDSI HPYTPFEVKI RSYNRRGDGP
810 820 830 840 850
ESLTAIVYSA EEEPKVAPAK VWAKGSSSSE MNVSWEPVLQ DMNGILLGYE
860 870 880 890 900
IRYWKAGDKE AAADRVRTAG LDSSARVTGL YPNTKYHVTV RAYNRAGTGP
910 920 930 940 950
ASPSADAMTM KPPPRRPPGN ISWTFSSSSL SLKWDPVVPL RNESTVTGYK
960 970 980 990 1000
MLYQNDLQPT PMLHLTSKNW IEIPVPEDIG HALVQIRTTG PGGDGIPAEV
1010 1020 1030 1040
HIVRNGGTSM MVESSAVRPA HPGPVFSCMV ILMLAGCQRL
Length:1,040
Mass (Da):113,217
Last modified:August 31, 2004 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i012C05DDF7F97462
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A087WQQ9A0A087WQQ9_MOUSE
Contactin-2
Cntn2
544Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WPI9A0A087WPI9_MOUSE
Contactin-2
Cntn2
102Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WPS6A0A087WPS6_MOUSE
Contactin-2
Cntn2
25Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WST5A0A087WST5_MOUSE
Contactin-2
Cntn2
34Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti665I → M in CAA57130 (Ref. 2) Curated1
Sequence conflicti861A → R in CAA57130 (Ref. 2) Curated1
Sequence conflicti881Y → N in CAA57130 (Ref. 2) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC066106 mRNA Translation: AAH66106.1
BC053033 mRNA Translation: AAH53033.1
X81365 mRNA Translation: CAA57130.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS15288.1

NCBI Reference Sequences

More...
RefSeqi
NP_796103.2, NM_177129.5
XP_006529425.1, XM_006529362.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000086521; ENSMUSP00000083707; ENSMUSG00000053024

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
21367

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:21367

UCSC genome browser

More...
UCSCi
uc007cpa.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC066106 mRNA Translation: AAH66106.1
BC053033 mRNA Translation: AAH53033.1
X81365 mRNA Translation: CAA57130.1
CCDSiCCDS15288.1
RefSeqiNP_796103.2, NM_177129.5
XP_006529425.1, XM_006529362.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5E7LX-ray2.00A609-911[»]
SMRiQ61330
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGRIDi203974, 11 interactors
IntActiQ61330, 2 interactors
STRINGi10090.ENSMUSP00000083707

PTM databases

GlyConnecti2225, 6 N-Linked glycans (4 sites)
GlyGeniQ61330, 11 sites
iPTMnetiQ61330
PhosphoSitePlusiQ61330

Proteomic databases

MaxQBiQ61330
PaxDbiQ61330
PeptideAtlasiQ61330
PRIDEiQ61330

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
670, 261 antibodies

Genome annotation databases

EnsembliENSMUST00000086521; ENSMUSP00000083707; ENSMUSG00000053024
GeneIDi21367
KEGGimmu:21367
UCSCiuc007cpa.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
6900
MGIiMGI:104518, Cntn2

Phylogenomic databases

eggNOGiKOG3513, Eukaryota
GeneTreeiENSGT00940000159193
HOGENOMiCLU_005756_0_0_1
InParanoidiQ61330
KOiK06760
OMAiHYVYRNE
OrthoDBi655902at2759
PhylomeDBiQ61330
TreeFamiTF351103

Enzyme and pathway databases

ReactomeiR-MMU-376176, Signaling by ROBO receptors

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

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BioGRID-ORCSi
21367, 1 hit in 19 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Cntn2, mouse

Protein Ontology

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PROi
PR:Q61330
RNActiQ61330, protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000053024, Expressed in cortical plate and 162 other tissues
GenevisibleiQ61330, MM

Family and domain databases

CDDicd00063, FN3, 3 hits
Gene3Di2.60.40.10, 10 hits
InterProiView protein in InterPro
IPR043204, Basigin-like
IPR032991, Contactin-2
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
PANTHERiPTHR10075, PTHR10075, 1 hit
PTHR10075:SF55, PTHR10075:SF55, 1 hit
PfamiView protein in Pfam
PF00041, fn3, 3 hits
PF07679, I-set, 2 hits
SMARTiView protein in SMART
SM00060, FN3, 4 hits
SM00409, IG, 6 hits
SM00408, IGc2, 5 hits
SUPFAMiSSF48726, SSF48726, 6 hits
SSF49265, SSF49265, 2 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 4 hits
PS50835, IG_LIKE, 6 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiCNTN2_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q61330
Secondary accession number(s): Q6NZJ4, Q7TSJ5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: August 31, 2004
Last modified: August 12, 2020
This is version 173 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
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