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UniProtKB - Q61048 (WBP4_MOUSE)

Entry version 141 (12 Aug 2020)
Sequence version 4 (27 Jul 2011)
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Protein

WW domain-binding protein 4

Gene

Wbp4

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in pre-mRNA splicing as a component of the spliceosome. May play a role in cross-intron bridging of U1 and U2 snRNPs in the mammalian A complex.1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri11 – 42Matrin-typePROSITE-ProRule annotationAdd BLAST32

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processmRNA processing, mRNA splicing
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...Reactomei		R-MMU-72163, mRNA Splicing - Major Pathway

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
WW domain-binding protein 4
Short name:
WBP-4
Alternative name(s):
Formin-binding protein 21
WW domain-containing-binding protein 4
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Wbp4
Synonyms:Fbp21, Fnbp21
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...MGIi		MGI:109568, Wbp4

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus, Spliceosome

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000760661 – 376WW domain-binding protein 4Add BLAST376

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei228PhosphoserineBy similarity1
Modified residuei230PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q61048

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q61048

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q61048

PRoteomics IDEntifications database

More...PRIDEi		Q61048

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q61048

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q61048

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSMUSG00000022023, Expressed in pancreas and 306 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q61048, baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q61048, MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the spliceosome B complex (PubMed:9724750). Associated with U2 snRNPs. Binds splicing factors SNRPB, SNRPC and SF1 (PubMed:9724750).

Interacts via the WW domains with the Pro-rich domains of KHDRBS1/SAM68 (PubMed:10748127).

Interacts via the WW domains with the Pro-rich domains of WBP11 (By similarity).

By similarity2 Publications

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...BioGRIDi		204548, 4 interactors

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...ELMi		Q61048

STRING: functional protein association networks

More...STRINGi		10090.ENSMUSP00000022601

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q61048, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q61048

Database of comparative protein structure models

More...ModBasei		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini123 – 156WW 1PROSITE-ProRule annotationAdd BLAST34
Domaini164 – 197WW 2PROSITE-ProRule annotationAdd BLAST34

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi113 – 122Poly-Lys10
Compositional biasi115 – 126Lys-richAdd BLAST12

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The WW domain recognizes the proline, glycine and methionine-rich (PGM) motif present in the splicing factors, as well as the Arg/Gly-rich-flanked Pro-rich domains found in several WW domain-binding proteins.

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri11 – 42Matrin-typePROSITE-ProRule annotationAdd BLAST32

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		KOG0150, Eukaryota

Ensembl GeneTree

More...GeneTreei		ENSGT00390000013956

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_050927_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q61048

KEGG Orthology (KO)

More...KOi		K13220

Identification of Orthologs from Complete Genome Data

More...OMAi		ANPYGVW

Database of Orthologous Groups

More...OrthoDBi		1585242at2759

TreeFam database of animal gene trees

More...TreeFami		TF316671

Family and domain databases

Conserved Domains Database

More...CDDi		cd00201, WW, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR000690, Matrin/U1-C_Znf_C2H2
IPR003604, Matrin/U1-like-C_Znf_C2H2
IPR013085, U1-CZ_Znf_C2H2
IPR040023, WBP4
IPR001202, WW_dom
IPR036020, WW_dom_sf
IPR036236, Znf_C2H2_sf

The PANTHER Classification System

More...PANTHERi		PTHR13173, PTHR13173, 1 hit

Pfam protein domain database

More...Pfami		View protein in Pfam
PF00397, WW, 2 hits
PF06220, zf-U1, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00456, WW, 2 hits
SM00451, ZnF_U1, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF51045, SSF51045, 2 hits
SSF57667, SSF57667, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS01159, WW_DOMAIN_1, 1 hit
PS50020, WW_DOMAIN_2, 2 hits
PS50171, ZF_MATRIN, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q61048-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MADYWKSQPK KFCDYCKCWI ADNRPSVEFH ERGKNHKENV ARRISEIKQK 
        60         70         80         90        100
SLDKAKEEEK ASKEFAAMEA AALKAYQEDL KRLGLPLPSD ISEPTVSPVI 
       110        120        130        140        150
STVQPTPTSN QQKEKKKKKK KKEASKGGWV EGVTADGHCY YYDLITGASQ 
       160        170        180        190        200
WEKPEGFQGN LKKTAAKAVW VEGLSEDGYT YYYNTETGES KWEKPEDFIP 
       210        220        230        240        250
HGGDVLSSKD SGKLPDTLED AKSSDSHSDS EGEQKKAGEA STETKKLIIK 
       260        270        280        290        300
FKEKNKSTEK RIGPEIQKEK STPKQNPSNT NEEKPKTLKK STNPYGEWQE 
       310        320        330        340        350
IKQEAESQEE VDLELPSTEG ECLSTSEAGV GEIKVVFKEK TVSSLGVAAD 
       360        370 
GVAPVFKKRR LENGKSRNLR QRGDDE
Length:376
Mass (Da):42,137
Last modified:July 27, 2011 - v4
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iECA7288FC94F3F83
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A2I3BQA9A0A2I3BQA9_MOUSE
WW domain-binding protein 4
Wbp4
315Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti80 – 83LKRL → SEKA in AAC34810 (PubMed:9724750).Curated4
Sequence conflicti155E → K in AAH34851 (Ref. 3) Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF071184 mRNA Translation: AAC34810.1
AK019160 mRNA Translation: BAB31575.3
AK135215 mRNA Translation: BAE22462.1
AK160559 mRNA Translation: BAE35873.1
AK162009 mRNA Translation: BAE36679.1
CH466535 Genomic DNA Translation: EDL35764.1
BC034851 mRNA Translation: AAH34851.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS27300.1

Protein sequence database of the Protein Information Resource

More...PIRi		S64714

NCBI Reference Sequences

More...RefSeqi		NP_061235.2, NM_018765.3

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENSMUST00000022601; ENSMUSP00000022601; ENSMUSG00000022023

Database of genes from NCBI RefSeq genomes

More...GeneIDi		22380

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		mmu:22380

UCSC genome browser

More...UCSCi		uc007uta.1, mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF071184 mRNA Translation: AAC34810.1
AK019160 mRNA Translation: BAB31575.3
AK135215 mRNA Translation: BAE22462.1
AK160559 mRNA Translation: BAE35873.1
AK162009 mRNA Translation: BAE36679.1
CH466535 Genomic DNA Translation: EDL35764.1
BC034851 mRNA Translation: AAH34851.1
CCDSiCCDS27300.1
PIRiS64714
RefSeqiNP_061235.2, NM_018765.3

3D structure databases

SMRiQ61048
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi204548, 4 interactors
ELMiQ61048
STRINGi10090.ENSMUSP00000022601

PTM databases

iPTMnetiQ61048
PhosphoSitePlusiQ61048

Proteomic databases

EPDiQ61048
MaxQBiQ61048
PaxDbiQ61048
PRIDEiQ61048

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...Antibodypediai		42181, 51 antibodies

Genome annotation databases

EnsembliENSMUST00000022601; ENSMUSP00000022601; ENSMUSG00000022023
GeneIDi22380
KEGGimmu:22380
UCSCiuc007uta.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		11193
MGIiMGI:109568, Wbp4

Phylogenomic databases

eggNOGiKOG0150, Eukaryota
GeneTreeiENSGT00390000013956
HOGENOMiCLU_050927_1_0_1
InParanoidiQ61048
KOiK13220
OMAiANPYGVW
OrthoDBi1585242at2759
TreeFamiTF316671

Enzyme and pathway databases

ReactomeiR-MMU-72163, mRNA Splicing - Major Pathway

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...BioGRID-ORCSi		22380, 4 hits in 21 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		Wbp4, mouse

Protein Ontology

More...PROi		PR:Q61048
RNActiQ61048, protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSMUSG00000022023, Expressed in pancreas and 306 other tissues
ExpressionAtlasiQ61048, baseline and differential
GenevisibleiQ61048, MM

Family and domain databases

CDDicd00201, WW, 2 hits
InterProiView protein in InterPro
IPR000690, Matrin/U1-C_Znf_C2H2
IPR003604, Matrin/U1-like-C_Znf_C2H2
IPR013085, U1-CZ_Znf_C2H2
IPR040023, WBP4
IPR001202, WW_dom
IPR036020, WW_dom_sf
IPR036236, Znf_C2H2_sf
PANTHERiPTHR13173, PTHR13173, 1 hit
PfamiView protein in Pfam
PF00397, WW, 2 hits
PF06220, zf-U1, 1 hit
SMARTiView protein in SMART
SM00456, WW, 2 hits
SM00451, ZnF_U1, 1 hit
SUPFAMiSSF51045, SSF51045, 2 hits
SSF57667, SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS01159, WW_DOMAIN_1, 1 hit
PS50020, WW_DOMAIN_2, 2 hits
PS50171, ZF_MATRIN, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiWBP4_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q61048
Secondary accession number(s): Q3TUU8, Q8K1Z9, Q9CS45
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: July 27, 2011
Last modified: August 12, 2020
This is version 141 of the entry and version 4 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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