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Entry version 118 (02 Jun 2021)
Sequence version 1 (23 Nov 2004)
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Protein

ALS2 C-terminal-like protein

Gene

Als2cl

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics (By similarity).

By similarity1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionGTPase activation

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-8876198, RAB GEFs exchange GTP for GDP on RABs

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ALS2 C-terminal-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Als2cl
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:2447532, Als2cl

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cytoplasm

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003138501 – 952ALS2 C-terminal-like proteinAdd BLAST952

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q60I26

PeptideAtlas

More...
PeptideAtlasi
Q60I26

PRoteomics IDEntifications database

More...
PRIDEi
Q60I26

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
296162 [Q60I26-1]
296163 [Q60I26-2]
296164 [Q60I26-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q60I26

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q60I26

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart, lung, liver and kidney.1 Publication

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Homodimer.

Forms a heteromeric complex with ALS2.

Interacts with ALS2 and RAB5A.

2 Publications

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000115718

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q60I26, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q60I26

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati358 – 380MORN 1Add BLAST23
Repeati381 – 403MORN 2Add BLAST23
Repeati409 – 431MORN 3Add BLAST23
Repeati432 – 454MORN 4Add BLAST23
Repeati459 – 481MORN 5Add BLAST23
Repeati483 – 505MORN 6Add BLAST23
Repeati506 – 528MORN 7Add BLAST23
Repeati529 – 552MORN 8Add BLAST24
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini795 – 941VPS9PROSITE-ProRule annotationAdd BLAST147

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0231, Eukaryota

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q60I26

Database of Orthologous Groups

More...
OrthoDBi
37470at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q60I26

TreeFam database of animal gene trees

More...
TreeFami
TF331793

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.1050.80, 1 hit
1.20.900.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035899, DBL_dom_sf
IPR003409, MORN
IPR003123, VPS9
IPR037191, VPS9_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02493, MORN, 6 hits
PF02204, VPS9, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00698, MORN, 7 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF109993, SSF109993, 1 hit
SSF48065, SSF48065, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51205, VPS9, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 2 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q60I26-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSSSEEADLL RLEEVFSTTL ARTISLILQP LLLADPEPSD PCGKECLRLL
60 70 80 90 100
QQLHESAQRL WYVTEQSLLS LRQRLYHPPS KGLEAVLLLS NADHVLQAHM
110 120 130 140 150
EYIKSYTDCV VAQAFQKVSK KRSEFWRSQR KALRQLLSSG SSEGSVGTTM
160 170 180 190 200
CQALRQPLSQ HVQKYLLLLL SLRDTLDESH PAQELVMHAI TLFGNLQSFM
210 220 230 240 250
GQALDQAVAT QALWHSLSSR LRDVLCSPAH RLLQDSQDIP VVVTPLRAER
260 270 280 290 300
VLLFDDSLVL LQGHNTHTFD LKLVWVKPGQ DKCVLHILTP EEEISFCTRD
310 320 330 340 350
PQGQVVWQWK VTQAVCQALC GKKDFPVLGS GRETSVPPEC RCVAYTFCRE
360 370 380 390 400
GRLCQATYDG EWCRAKPHGK GTLKWPDGRN HVGTFYQGLE HGFGICLVPQ
410 420 430 440 450
ASEDKFDCYK CHWREGRMCE YGICEYGTDE VYKGYFQAGL RHGFGILESA
460 470 480 490 500
PQAPQPFRYT GHWERGQRSG YGIEEDRDRG ERYIGMWQAD QRHGPGVVVT
510 520 530 540 550
QAGVCYQGTF QGDKMAGPGI LLCEDDSLYE GTFTRDLTLL GKGKVTFPNG
560 570 580 590 600
FTLDGSFSSG TDKGLYTQGV LDTAALPPDP SSTRKRQLGL GTFPVESRWQ
610 620 630 640 650
GVYSPFRDFL RLGCPGEQQE ALLGFHTQSS RELRKSQECL CCERSHPEDC
660 670 680 690 700
VGSMEDTLKE LLQHRKPKAL QQYLRKALSN SRHPLGQLLR TLMLTFQATY
710 720 730 740 750
SGIGANKHLQ EMAQEEVKQH ARELWAAYRG LLKVALQHQG QTLEEENMET
760 770 780 790 800
RDLQVHGLLL PLILPSFYSE LFTLYLLLHE REDGLYSRGI TNLSLFPDTK
810 820 830 840 850
LLEFLDVQKH LWPLKDLKLT SNQRYSLVRD KCFLTATECL QKIITTVHPR
860 870 880 890 900
EKLEVLEKTY GEIEATVSRV LGCKYKLPMD DLLPLLIYVV SRARIQHLGA
910 920 930 940 950
EIHLIRDMMD PVHTGGLHDF LLTALESCYE HIQKEDMRPH HLPGHWDARD

LW
Length:952
Mass (Da):108,146
Last modified:November 23, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i8D730F53AA313A08
GO
Isoform 2 (identifier: Q60I26-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     645-747: Missing.

Show »
Length:849
Mass (Da):96,347
Checksum:iB49C2BA585898B60
GO
Isoform 3 (identifier: Q60I26-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-692: Missing.

Show »
Length:260
Mass (Da):30,246
Checksum:i0916E0892F482216
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0R4J1X4A0A0R4J1X4_MOUSE
ALS2 C-terminal-like protein
Als2cl
952Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0G2JEP6A0A0G2JEP6_MOUSE
ALS2 C-terminal-like protein
Als2cl
39Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAD21399 differs from that shown. Intron retention.Curated
The sequence BAD21399 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti141S → N in AAM89221 (PubMed:12140191).Curated1
Sequence conflicti141S → N in BAC35257 (PubMed:16141072).Curated1
Sequence conflicti348C → R in AAM89221 (PubMed:12140191).Curated1
Sequence conflicti348C → R in BAC35257 (PubMed:16141072).Curated1
Sequence conflicti738H → R in AAM89221 (PubMed:12140191).Curated1
Sequence conflicti738H → R in BAC35257 (PubMed:16141072).Curated1
Sequence conflicti738H → R in BAC27145 (PubMed:16141072).Curated1
Sequence conflicti939P → L in AAM89221 (PubMed:12140191).Curated1
Sequence conflicti939P → L in BAC35257 (PubMed:16141072).Curated1
Sequence conflicti939P → L in BAC27145 (PubMed:16141072).Curated1
Sequence conflicti950D → E in AAM89221 (PubMed:12140191).Curated1
Sequence conflicti950D → E in BAC35257 (PubMed:16141072).Curated1
Sequence conflicti950D → E in BAC27145 (PubMed:16141072).Curated1
Sequence conflicti950D → E in AAH22645 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0301721 – 692Missing in isoform 3. 1 PublicationAdd BLAST692
Alternative sequenceiVSP_030173645 – 747Missing in isoform 2. 1 PublicationAdd BLAST103

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF481142 mRNA Translation: AAM89221.1
AB107016 mRNA Translation: BAD51818.1
AK131149 Transcribed RNA Translation: BAD21399.1 Sequence problems.
AK030815 mRNA Translation: BAC27145.1
AK053076 mRNA Translation: BAC35257.1
AK155451 mRNA Translation: BAE33270.1
BC022645 mRNA Translation: AAH22645.1
BC117928 mRNA Translation: AAI17929.1
BC117929 mRNA Translation: AAI17930.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS23579.1 [Q60I26-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001139531.1, NM_001146059.1
NP_001139532.1, NM_001146060.1
NP_666340.3, NM_146228.4
XP_006512166.1, XM_006512103.2
XP_017168843.1, XM_017313354.1
XP_017168844.1, XM_017313355.1
XP_017168845.1, XM_017313356.1
XP_017168846.1, XM_017313357.1
XP_017168847.1, XM_017313358.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
235633

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:235633

UCSC genome browser

More...
UCSCi
uc009rvc.2, mouse [Q60I26-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF481142 mRNA Translation: AAM89221.1
AB107016 mRNA Translation: BAD51818.1
AK131149 Transcribed RNA Translation: BAD21399.1 Sequence problems.
AK030815 mRNA Translation: BAC27145.1
AK053076 mRNA Translation: BAC35257.1
AK155451 mRNA Translation: BAE33270.1
BC022645 mRNA Translation: AAH22645.1
BC117928 mRNA Translation: AAI17929.1
BC117929 mRNA Translation: AAI17930.1
CCDSiCCDS23579.1 [Q60I26-1]
RefSeqiNP_001139531.1, NM_001146059.1
NP_001139532.1, NM_001146060.1
NP_666340.3, NM_146228.4
XP_006512166.1, XM_006512103.2
XP_017168843.1, XM_017313354.1
XP_017168844.1, XM_017313355.1
XP_017168845.1, XM_017313356.1
XP_017168846.1, XM_017313357.1
XP_017168847.1, XM_017313358.1

3D structure databases

SMRiQ60I26
ModBaseiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000115718

PTM databases

iPTMnetiQ60I26
PhosphoSitePlusiQ60I26

Proteomic databases

PaxDbiQ60I26
PeptideAtlasiQ60I26
PRIDEiQ60I26
ProteomicsDBi296162 [Q60I26-1]
296163 [Q60I26-2]
296164 [Q60I26-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
235633

Genome annotation databases

GeneIDi235633
KEGGimmu:235633
UCSCiuc009rvc.2, mouse [Q60I26-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
259173
MGIiMGI:2447532, Als2cl

Phylogenomic databases

eggNOGiKOG0231, Eukaryota
InParanoidiQ60I26
OrthoDBi37470at2759
PhylomeDBiQ60I26
TreeFamiTF331793

Enzyme and pathway databases

ReactomeiR-MMU-8876198, RAB GEFs exchange GTP for GDP on RABs

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
235633, 4 hits in 52 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Als2cl, mouse

Protein Ontology

More...
PROi
PR:Q60I26
RNActiQ60I26, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

Gene3Di1.20.1050.80, 1 hit
1.20.900.10, 1 hit
InterProiView protein in InterPro
IPR035899, DBL_dom_sf
IPR003409, MORN
IPR003123, VPS9
IPR037191, VPS9_dom_sf
PfamiView protein in Pfam
PF02493, MORN, 6 hits
PF02204, VPS9, 1 hit
SMARTiView protein in SMART
SM00698, MORN, 7 hits
SUPFAMiSSF109993, SSF109993, 1 hit
SSF48065, SSF48065, 1 hit
PROSITEiView protein in PROSITE
PS51205, VPS9, 1 hit

MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAL2CL_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q60I26
Secondary accession number(s): Q6KAQ8
, Q8C0K7, Q8K468, Q8R222
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 23, 2004
Last modified: June 2, 2021
This is version 118 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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