UniProtKB - Q60881 (OL142_MOUSE)
Protein
Olfactory receptor 142
Gene
Olfr142
Organism
Mus musculus (Mouse)
Status
Functioni
Odorant receptor.Curated
GO - Molecular functioni
- G protein-coupled receptor activity Source: UniProtKB-KW
- olfactory receptor activity Source: MGI
GO - Biological processi
- G protein-coupled receptor signaling pathway Source: MGI
- sensory perception of smell Source: MGI
Keywordsi
Molecular function | G-protein coupled receptor, Receptor, Transducer |
Biological process | Olfaction, Sensory transduction |
Enzyme and pathway databases
Reactomei | R-MMU-381753 Olfactory Signaling Pathway |
Names & Taxonomyi
Protein namesi | Recommended name: Olfactory receptor 142Alternative name(s): Olfactory receptor 227-2 Olfactory receptor 4C |
Gene namesi | Name:Olfr142 Synonyms:Mor227-2, Olfr4 |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:2177525 Olfr142 |
Subcellular locationi
Plasma membrane
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: MGI
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 25 | ExtracellularSequence analysisAdd BLAST | 25 | |
Transmembranei | 26 – 46 | Helical; Name=1Sequence analysisAdd BLAST | 21 | |
Topological domaini | 47 – 55 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 56 – 76 | Helical; Name=2Sequence analysisAdd BLAST | 21 | |
Topological domaini | 77 – 95 | ExtracellularSequence analysisAdd BLAST | 19 | |
Transmembranei | 96 – 116 | Helical; Name=3Sequence analysisAdd BLAST | 21 | |
Topological domaini | 117 – 141 | CytoplasmicSequence analysisAdd BLAST | 25 | |
Transmembranei | 142 – 162 | Helical; Name=4Sequence analysisAdd BLAST | 21 | |
Topological domaini | 163 – 202 | ExtracellularSequence analysisAdd BLAST | 40 | |
Transmembranei | 203 – 223 | Helical; Name=5Sequence analysisAdd BLAST | 21 | |
Topological domaini | 224 – 236 | CytoplasmicSequence analysisAdd BLAST | 13 | |
Transmembranei | 237 – 257 | Helical; Name=6Sequence analysisAdd BLAST | 21 | |
Topological domaini | 258 – 266 | ExtracellularSequence analysis | 9 | |
Transmembranei | 267 – 287 | Helical; Name=7Sequence analysisAdd BLAST | 21 | |
Topological domaini | 288 – 305 | CytoplasmicSequence analysisAdd BLAST | 18 |
Keywords - Cellular componenti
Cell membrane, MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000150819 | 1 – 305 | Olfactory receptor 142Add BLAST | 305 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 6 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Disulfide bondi | 95 ↔ 187 | PROSITE-ProRule annotation |
Keywords - PTMi
Disulfide bond, GlycoproteinProteomic databases
PaxDbi | Q60881 |
PRIDEi | Q60881 |
PTM databases
iPTMneti | Q60881 |
PhosphoSitePlusi | Q60881 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000075063 Expressed in 2 organ(s), highest expression level in olfactory epithelium |
Family & Domainsi
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.PROSITE-ProRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
GeneTreei | ENSGT00940000155395 |
HOGENOMi | HOG000041362 |
HOVERGENi | HBG017625 |
InParanoidi | Q60881 |
KOi | K04257 |
OMAi | GFIVMAN |
OrthoDBi | 1082090at2759 |
PhylomeDBi | Q60881 |
TreeFami | TF337251 |
Family and domain databases
InterProi | View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt |
Pfami | View protein in Pfam PF13853 7tm_4, 1 hit |
PRINTSi | PR00237 GPCRRHODOPSN PR00245 OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
Q60881-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANKNNVTEL IFTGLFQDPE VQKVCFVLFL PVYLATLLGN SLILVAVSIS
60 70 80 90 100
KTLHSPMYFF LSSLSLVEIC YSSTIVPKFI TDLLAKVKTI SLKGCLTQIF
110 120 130 140 150
FSHFFGVVEV ILLVVMAYDR YVAICKPLHY MNIMSRQVCH MLVAGSWLGG
160 170 180 190 200
FIHSIIQIII TIPLPFCGPN VIDHYFCDLQ QLFKLACTDT FMEGFIVMAN
210 220 230 240 250
SGLISIVSLF ILVSSYAVIL ISLRKRSAEG RRKALSTCAS HITVVILFFV
260 270 280 290 300
PGAFIYMRPS STFTEDKLVS VFYTVITPML NPIVYTLRNT EMKNAIRMSW
KQKDS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY073104 Genomic DNA Translation: AAL60767.1 AY318475 Genomic DNA Translation: AAP71664.1 U28770 Genomic DNA Translation: AAC52393.1 |
CCDSi | CCDS16410.1 |
RefSeqi | NP_667195.1, NM_146984.1 |
UniGenei | Mm.377948 |
Genome annotation databases
Ensembli | ENSMUST00000099752; ENSMUSP00000097341; ENSMUSG00000075063 ENSMUST00000213968; ENSMUSP00000150216; ENSMUSG00000075063 |
GeneIDi | 406186 |
KEGGi | mmu:406186 |
UCSCi | uc008ksp.1 mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY073104 Genomic DNA Translation: AAL60767.1 AY318475 Genomic DNA Translation: AAP71664.1 U28770 Genomic DNA Translation: AAC52393.1 |
CCDSi | CCDS16410.1 |
RefSeqi | NP_667195.1, NM_146984.1 |
UniGenei | Mm.377948 |
3D structure databases
ProteinModelPortali | Q60881 |
ModBasei | Search... |
MobiDBi | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000097341 |
Protein family/group databases
GPCRDBi | Search... |
PTM databases
iPTMneti | Q60881 |
PhosphoSitePlusi | Q60881 |
Proteomic databases
PaxDbi | Q60881 |
PRIDEi | Q60881 |
Protocols and materials databases
DNASUi | 406186 |
Structural Biology Knowledgebase | Search... |
Genome annotation databases
Ensembli | ENSMUST00000099752; ENSMUSP00000097341; ENSMUSG00000075063 ENSMUST00000213968; ENSMUSP00000150216; ENSMUSG00000075063 |
GeneIDi | 406186 |
KEGGi | mmu:406186 |
UCSCi | uc008ksp.1 mouse |
Organism-specific databases
CTDi | 406186 |
MGIi | MGI:2177525 Olfr142 |
Phylogenomic databases
GeneTreei | ENSGT00940000155395 |
HOGENOMi | HOG000041362 |
HOVERGENi | HBG017625 |
InParanoidi | Q60881 |
KOi | K04257 |
OMAi | GFIVMAN |
OrthoDBi | 1082090at2759 |
PhylomeDBi | Q60881 |
TreeFami | TF337251 |
Enzyme and pathway databases
Reactomei | R-MMU-381753 Olfactory Signaling Pathway |
Miscellaneous databases
PROi | PR:Q60881 |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000075063 Expressed in 2 organ(s), highest expression level in olfactory epithelium |
Family and domain databases
InterProi | View protein in InterPro IPR000276 GPCR_Rhodpsn IPR017452 GPCR_Rhodpsn_7TM IPR000725 Olfact_rcpt |
Pfami | View protein in Pfam PF13853 7tm_4, 1 hit |
PRINTSi | PR00237 GPCRRHODOPSN PR00245 OLFACTORYR |
PROSITEi | View protein in PROSITE PS00237 G_PROTEIN_RECEP_F1_1, 1 hit PS50262 G_PROTEIN_RECEP_F1_2, 1 hit |
ProtoNeti | Search... |
Entry informationi
Entry namei | OL142_MOUSE | |
Accessioni | Q60881Primary (citable) accession number: Q60881 Secondary accession number(s): Q8VGP2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | August 22, 2003 |
Last sequence update: | January 10, 2006 | |
Last modified: | February 13, 2019 | |
This is version 136 of the entry and version 2 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families - MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - 7-transmembrane G-linked receptors
List of 7-transmembrane G-linked receptor entries