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Entry version 121 (07 Oct 2020)
Sequence version 3 (05 Sep 2012)
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Protein

Inactive 2'-5'-oligoadenylate synthase 1B

Gene

Oas1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Does not have 2'-5'-OAS activity, but can bind double-stranded RNA (PubMed:12396720, PubMed:27663720). The full-length protein displays antiviral activity against flaviviruses such as west Nile virus (WNV) via an alternative antiviral pathway independent of RNase L (PubMed:12080145, PubMed:16371364, PubMed:17904183, PubMed:27663720). The truncated form of the protein lacks antiviral activity (PubMed:12080145, PubMed:16371364, PubMed:17904183).5 Publications

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding
Biological processAntiviral defense, Immunity, Innate immunity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Inactive 2'-5'-oligoadenylate synthase 1B
Short name:
(2-5')oligo(A) synthase 1B
Short name:
2-5A synthase 1B
Alternative name(s):
2'-5'-oligoadenylate synthase-like protein 1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Oas1b
Synonyms:Flv, Oias2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unplaced

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:97430, Oas1b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini1 – 351CytoplasmicSequence analysisAdd BLAST351
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei352 – 370Helical; Anchor for type IV membrane proteinSequence analysisAdd BLAST19
Topological domaini371 – 376ExtracellularSequence analysis6

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001602611 – 376Inactive 2'-5'-oligoadenylate synthase 1BAdd BLAST376

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q60856

PeptideAtlas

More...
PeptideAtlasi
Q60856

PRoteomics IDEntifications database

More...
PRIDEi
Q60856

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Highly expressed in lung, spleen and thymus (PubMed:12396720, PubMed:12186974). Also detected at lower levels in heart, kidney, liver, lung, skeletal muscle, testes, uterus and ovaries (PubMed:12396720, PubMed:12186974, PubMed:27663720).3 Publications

<p>This subsection of the 'Expression' section provides information on the expression of the gene product at various stages of a cell, tissue or organism development. By default, the information is derived from experiments at the mRNA level, unless specified 'at the protein level'.<p><a href='/help/developmental_stage' target='_top'>More...</a></p>Developmental stagei

Detected 1 week after birth in developing skin, testes, ovary, kidney and lung.1 Publication

<p>This subsection of the 'Expression' section reports the experimentally proven effects of inducers and repressors (usually chemical compounds or environmental factors) on the level of protein (or mRNA) expression (up-regulation, down-regulation, constitutive expression).<p><a href='/help/induction' target='_top'>More...</a></p>Inductioni

Up-regulated by the type I interferon IFNB1, in a STAT2-dependent manner (PubMed:22305621). Induced by polyinosinic:polycytidylic acid (poly I:C) (PubMed:12396720, PubMed:27663720).3 Publications

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with OSBPL1A and ABCF3.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

More...
BioGRIDi
204822, 1 interactor

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q60856, protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q60856

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the 2-5A synthase family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q60856

KEGG Orthology (KO)

More...
KOi
K14216

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1410.20, 1 hit
3.30.460.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018952, 2-5-oligoAdlate_synth_1_dom2/C
IPR038121, 2-5-oligoAdlate_synth_2_sf
IPR026774, 2-5A_synthase
IPR006117, 2-5OAS_C_CS
IPR043519, NT_sf

The PANTHER Classification System

More...
PANTHERi
PTHR11258, PTHR11258, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10421, OAS1_C, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81301, SSF81301, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00833, 25A_SYNTH_2, 1 hit
PS50152, 25A_SYNTH_3, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q60856-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEQDLRSIPA SKLDKFIENH LPDTSFCADL REVIDALCAL LKDRSFRGPV
60 70 80 90 100
RRMRASKGVK GKGTTLKGRS DADLVVFLNN LTSFEDQLNQ QGVLIKEIKK
110 120 130 140 150
QLCEVQHERR CGVKFEVHSL RSPNSRALSF KLSAPDLLKE VKFDVLPAYD
160 170 180 190 200
LLDHLNILKK PNQQFYANLI SGRTPPGKEG KLSICFMGLR KYFLNCRPTK
210 220 230 240 250
LKRLIRLVTH WYQLCKEKLG DPLPPQYALE LLTVYAWEYG SRVTKFNTAQ
260 270 280 290 300
GFRTVLELVT KYKQLQIYWT VYYDFRHQEV SEYLHQQLKK DRPVILDPAD
310 320 330 340 350
PTRNIAGLNP KDWRRLAGEA AAWLQYPCFK YRDGSSVCSW EVPTEVGVPM
360 370
KYLLCRIFWL LFWSLFHFIF GKTSSG
Length:376
Mass (Da):43,620
Last modified:September 5, 2012 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0733589FC702D4C7
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
V5IRT6V5IRT6_MOUSE
Inactive 2'-5'-oligoadenylate synth...
Oas1b
251Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB84129 differs from that shown. Reason: Frameshift.Curated
The sequence CAA39455 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti58 – 60GVK → VFQ in CAA39455 (PubMed:1709495).Curated3
Sequence conflicti234 – 235VY → LD in BAB84129 (PubMed:12396720).Curated2
Sequence conflicti234 – 235VY → LD in CAA39455 (PubMed:1709495).Curated2

<p>This subsection of the 'Sequence' section provides information on polymorphic variants. If the variant is associated with a disease state, the description of the latter can be found in the <a href="http://www.uniprot.org/manual/involvement%5Fin%5Fdisease">'Involvement in disease'</a> subsection.<p><a href='/help/polymorphism' target='_top'>More...</a></p>Polymorphismi

A nonsense mutation in exon 4 results in a premature stop codon leading to a truncated form which determines the resistant/susceptible phenotype of the mice to flaviviruses. Mice encoding the full-length protein show a flavivirus resistance phenotype (Flv(r)), whereas mice encoding a C-terminally truncated protein show a flavivirus susceptible phenotype (Flv(s)).3 Publications

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural varianti36A → S in strain: BID, DHA, MPR. 1 Publication1
Natural varianti45S → F in strain: MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti47R → Q in strain: DHA. 1 Publication1
Natural varianti50V → G in strain: DHA. 1 Publication1
Natural varianti63G → C in strain: BID, DHA, MPR, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti65T → A in strain: BALB/c, BID, C57BL/6J, C3H/He, MBT/Pas, PWD/Phj. 7 Publications1
Natural varianti83S → Y in strain: BID, DHA, MPR, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti90Q → R in strain: DHA. 1 Publication1
Natural varianti103C → Y in strain: MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti105V → I in strain: DHA. 1 Publication1
Natural varianti111C → F in strain: MPR, DHA, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti118H → Q in strain: MPR, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti151L → V in strain: BID, MPR. 1 Publication1
Natural varianti176P → L in strain: MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti181K → E in strain: DHA. 1 Publication1
Natural varianti183S → L in strain: BID, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti184I → T in strain: BID, DHA, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti190R → Q in strain: BALB/c, C57BL/6J, C3H/He. 6 Publications1
Natural varianti206R → H in strain: MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti253 – 376Missing in the truncated form. Add BLAST124
Natural varianti266Q → R in strain: BID, C3H/RV, DHA, MPR, MBT/Pas, PWD/Phj. 3 Publications1
Natural varianti277H → L in strain: BID. 1 Publication1
Natural varianti278Q → P in strain: DHA. 1 Publication1
Natural varianti291D → V in strain: DHA. 1 Publication1
Natural varianti299A → V in strain: MPR. 1 Publication1
Natural varianti305I → V in strain: MPR. 1 Publication1
Natural varianti322A → T in strain: C3H/RV. 1 Publication1
Natural varianti336S → P in strain: C3H/RV, DHA, MPR, MBT/Pas, PWD/Phj. 3 Publications1
Natural varianti347G → A in strain: DHA, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti350M → T in strain: BID, DHA, MBT/Pas, PWD/Phj. 2 Publications1
Natural varianti354L → F in strain: BID, C3H/RV, DHA, MPR, MBT/Pas, PWD/Phj. 3 Publications1
Natural varianti368F → L in strain: MPR. 1 Publication1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB067529 mRNA Translation: BAB84129.1 Frameshift.
AF328926 mRNA Translation: AAM47542.1
AF418004 mRNA Translation: AAM47544.1
AF418005 mRNA Translation: AAM47545.1
AF481734 Genomic DNA Translation: AAM49738.1
AF466822 mRNA Translation: AAM97603.1
AF466823 mRNA Translation: AAM97604.1
AM887907 Genomic DNA Translation: CAP12708.1
AM887915 Genomic DNA Translation: CAP12714.1
AM887917 Genomic DNA Translation: CAP12716.1
AM887918 Genomic DNA Translation: CAP12717.1
AM887919 Genomic DNA Translation: CAP12718.1
AC115937 Genomic DNA No translation available.
CH466529 Genomic DNA Translation: EDL19747.1
X55982 mRNA Translation: CAA39455.1 Frameshift.

Protein sequence database of the Protein Information Resource

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PIRi
S15661

NCBI Reference Sequences

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RefSeqi
NP_001077394.1, NM_001083925.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
23961

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:23961

UCSC genome browser

More...
UCSCi
uc008zie.1, mouse

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB067529 mRNA Translation: BAB84129.1 Frameshift.
AF328926 mRNA Translation: AAM47542.1
AF418004 mRNA Translation: AAM47544.1
AF418005 mRNA Translation: AAM47545.1
AF481734 Genomic DNA Translation: AAM49738.1
AF466822 mRNA Translation: AAM97603.1
AF466823 mRNA Translation: AAM97604.1
AM887907 Genomic DNA Translation: CAP12708.1
AM887915 Genomic DNA Translation: CAP12714.1
AM887917 Genomic DNA Translation: CAP12716.1
AM887918 Genomic DNA Translation: CAP12717.1
AM887919 Genomic DNA Translation: CAP12718.1
AC115937 Genomic DNA No translation available.
CH466529 Genomic DNA Translation: EDL19747.1
X55982 mRNA Translation: CAA39455.1 Frameshift.
PIRiS15661
RefSeqiNP_001077394.1, NM_001083925.1

3D structure databases

SMRiQ60856
ModBaseiSearch...

Protein-protein interaction databases

BioGRIDi204822, 1 interactor

Proteomic databases

PaxDbiQ60856
PeptideAtlasiQ60856
PRIDEiQ60856

Genome annotation databases

GeneIDi23961
KEGGimmu:23961
UCSCiuc008zie.1, mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
23961
MGIiMGI:97430, Oas1b

Phylogenomic databases

InParanoidiQ60856
KOiK14216

Miscellaneous databases

BioGRID ORCS database of CRISPR phenotype screens

More...
BioGRID-ORCSi
23961, 0 hits in 9 CRISPR screens

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Oas1g, mouse

Protein Ontology

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PROi
PR:Q60856
RNActiQ60856, protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Family and domain databases

Gene3Di1.10.1410.20, 1 hit
3.30.460.10, 1 hit
InterProiView protein in InterPro
IPR018952, 2-5-oligoAdlate_synth_1_dom2/C
IPR038121, 2-5-oligoAdlate_synth_2_sf
IPR026774, 2-5A_synthase
IPR006117, 2-5OAS_C_CS
IPR043519, NT_sf
PANTHERiPTHR11258, PTHR11258, 1 hit
PfamiView protein in Pfam
PF10421, OAS1_C, 1 hit
SUPFAMiSSF81301, SSF81301, 1 hit
PROSITEiView protein in PROSITE
PS00833, 25A_SYNTH_2, 1 hit
PS50152, 25A_SYNTH_3, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiOAS1B_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q60856
Secondary accession number(s): A8YPE5
, A8YPE7, A8YPE8, A8YPE9, E9QKP6, Q78ZX0, Q8JZN0, Q8JZN4, Q8VI98
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 21, 2001
Last sequence update: September 5, 2012
Last modified: October 7, 2020
This is version 121 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
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