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Entry version 83 (02 Jun 2021)
Sequence version 1 (23 Nov 2004)
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Protein
Submitted name:

Cation-transporting ATPase, E1-E2 family

Gene

MCA1915

Organism
Methylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Protein family/group databases

Transport Classification Database

More...
TCDBi
3.A.3.31.2, the p-type atpase (p-atpase) superfamily

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Cation-transporting ATPase, E1-E2 familyImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:MCA1915Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMethylococcus capsulatus (strain ATCC 33009 / NCIMB 11132 / Bath)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri243233 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaMethylococcalesMethylococcaceaeMethylococcus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006821 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei742 – 766HelicalSequence analysisAdd BLAST25

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

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STRINGi
243233.MCA1915

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
COG2217, Bacteria

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
CLU_288006_0_0_6

Identification of Orthologs from Complete Genome Data

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OMAi
KESEMAG

Database of Orthologous Groups

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OrthoDBi
1909646at2

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
3.40.50.1000, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR024787, EcsC
IPR023214, HAD_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12787, EcsC, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF81653, SSF81653, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q606U9-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAGRIAFGSS WLRIEDTGVF GPGRAKIARR FARRVFTLPE VESLELEPSR
60 70 80 90 100
GCALIRHRTA KTGVDAFRRR LAAAVDVEEE GRADRDLPQW PADSPVTLHR
110 120 130 140 150
HDDLISLFRI GSAANGWLEL QHPSLQGNAV RLRTIEAALG ALDAVRGVSG
160 170 180 190 200
HAASGTIRIR YHAGSLEPAA LLRVAEGLLI AETASCIPEP AAVDFRVANA
210 220 230 240 250
SVGLGAVGEL MLPLATPLAA GLLVAGNLRV LQDAGKQISH GKLGVAVFHT
260 270 280 290 300
ALLACSIATG QVLAYALTEW SLRYWQQNWR KHLTRETRAL LEDNLPIPAQ
310 320 330 340 350
TVLLSPEGIE SRVAPSDLRA GDRVKVSAPR IIPVDGVVLA GQALVQESSL
360 370 380 390 400
RGRPGLVRKT AGDEVLAGTV VANGSLDIQA VCTGPETRAA GLTRQVLDTA
410 420 430 440 450
SLMPADRTMR RRAEELADRT VFPTLATAGV GWAVGDLITV GAILHQDWVS
460 470 480 490 500
GPGMVLPMET LRAMRLAWRA GALLKSASAL ARMKYSDFLV IDGDLPGLLD
510 520 530 540 550
PQLELAEVAS QAPYTDTILR HAAGAGLFLG DERAEALARS CAQRGLVVRE
560 570 580 590 600
PELLSLDANA VEVRSGRHTV SLTGALSHSE AVTAPLRMRI DGTDVAELRF
610 620 630 640 650
TYSHRPRASQ TLASLRALGM RQIFVVSSRP EAETAELMRR LGADLSGGGL
660 670 680 690 700
NAEQKIRFLR GLKNRGVRTT LVGDFDKESE MAGEAHVTVG LVNPLGDSGP
710 720 730 740 750
CDIALLSESL DPLVALMELA RSHDANVVSA CRMAAIPNLL CIAGAFAGIL
760 770 780 790 800
NGITSGIIAN LGVVNVDRRL RRNLQMAKGA SRSASALNKP GARRSPEPSP
810 820 830 840 850
PVLLIGMKHL IPAMPPSHYE AEQIRAIAAW KRRKPHLASP LLNRARRPLV
860 870 880 890 900
RLGRKIIPAP ASRFALDALN KMAEQLVRDD WILRHGGIRS LEEIGAQSLE
910 920 930 940 950
FSDRLADKVI EEGLKLATGV GAVTGTGSLG TVLVGVPASL GVALRLIHRV
960 970 980 990 1000
SQAYGYSTER TGDRGFMLHI LALATAETAE ERTRALENYH WQLEHHLVGD
1010 1020 1030 1040 1050
AVNDAALAVL QRIVFGRKLA SFVPGLSVAL NAYANRSFSR RAGLAAKHVY
1060
QERWLLDRGR IAGWVAPT
Length:1,068
Mass (Da):114,551
Last modified:November 23, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iDACA2F2DAE75DC7A
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AE017282 Genomic DNA Translation: AAU92110.1

NCBI Reference Sequences

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RefSeqi
WP_010961163.1, NC_002977.6

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
AAU92110; AAU92110; MCA1915

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mca:MCA1915

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017282 Genomic DNA Translation: AAU92110.1
RefSeqiWP_010961163.1, NC_002977.6

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi243233.MCA1915

Protein family/group databases

TCDBi3.A.3.31.2, the p-type atpase (p-atpase) superfamily

Genome annotation databases

EnsemblBacteriaiAAU92110; AAU92110; MCA1915
KEGGimca:MCA1915

Phylogenomic databases

eggNOGiCOG2217, Bacteria
HOGENOMiCLU_288006_0_0_6
OMAiKESEMAG
OrthoDBi1909646at2

Family and domain databases

Gene3Di3.40.50.1000, 1 hit
InterProiView protein in InterPro
IPR008250, ATPase_P-typ_transduc_dom_A_sf
IPR024787, EcsC
IPR023214, HAD_sf
PfamiView protein in Pfam
PF12787, EcsC, 1 hit
SUPFAMiSSF81653, SSF81653, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ606U9_METCA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q606U9
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: June 2, 2021
This is version 83 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Reference proteomeImported
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