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Entry version 193 (11 Dec 2019)
Sequence version 2 (16 Oct 2013)
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Protein

Laminin subunit alpha-2

Gene

Lama2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processCell adhesion

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-3000157 Laminin interactions
R-MMU-8874081 MET activates PTK2 signaling

Protein family/group databases

UniLectin database of carbohydrate-binding proteins

More...
UniLectini
Q60675

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Laminin subunit alpha-2
Alternative name(s):
Laminin M chain
Laminin-12 subunit alpha
Laminin-2 subunit alpha
Laminin-4 subunit alpha
Merosin heavy chain
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Lama2
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:99912 Lama2

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Basement membrane, Extracellular matrix, Secreted

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

<p>This subsection of the ‘Pathology and Biotech’ section provides information on the disease(s) associated with genetic variations in a given protein. The information is extracted from the scientific literature and diseases that are also described in the <a href="http://www.ncbi.nlm.nih.gov/sites/entrez?db=omim">OMIM</a> database are represented with a <a href="http://www.uniprot.org/diseases">controlled vocabulary</a> in the following way:<p><a href='/help/involvement_in_disease' target='_top'>More...</a></p>Involvement in diseasei

Defects in Lama2 are a cause of murine muscular dystrophy (dy2J).

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 191 PublicationAdd BLAST19
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000001705720 – 3118Laminin subunit alpha-2Add BLAST3099

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi51N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi85N-linked (GlcNAc...) asparagineSequence analysis1
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi283 ↔ 292By similarity
Disulfide bondi285 ↔ 303By similarity
Glycosylationi299N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi305 ↔ 314By similarity
Disulfide bondi317 ↔ 337By similarity
Disulfide bondi340 ↔ 349By similarity
Disulfide bondi342 ↔ 374By similarity
Glycosylationi359N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi376N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi377 ↔ 386By similarity
Disulfide bondi389 ↔ 407By similarity
Disulfide bondi410 ↔ 422By similarity
Disulfide bondi412 ↔ 438By similarity
Disulfide bondi440 ↔ 449By similarity
Disulfide bondi452 ↔ 462By similarity
Disulfide bondi465 ↔ 478By similarity
Glycosylationi466N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi467 ↔ 482By similarity
Disulfide bondi484 ↔ 493By similarity
Disulfide bondi496 ↔ 511By similarity
Glycosylationi742N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi753 ↔ 762By similarity
Disulfide bondi755 ↔ 769By similarity
Disulfide bondi772 ↔ 781By similarity
Disulfide bondi784 ↔ 800By similarity
Disulfide bondi803 ↔ 818By similarity
Disulfide bondi805 ↔ 828By similarity
Disulfide bondi831 ↔ 840By similarity
Disulfide bondi843 ↔ 858By similarity
Disulfide bondi861 ↔ 875By similarity
Disulfide bondi863 ↔ 882By similarity
Disulfide bondi885 ↔ 894By similarity
Disulfide bondi897 ↔ 911By similarity
Disulfide bondi914 ↔ 926By similarity
Disulfide bondi916 ↔ 933By similarity
Glycosylationi919N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi935 ↔ 944By similarity
Disulfide bondi947 ↔ 960By similarity
Disulfide bondi963 ↔ 975By similarity
Disulfide bondi965 ↔ 981By similarity
Disulfide bondi983 ↔ 992By similarity
Disulfide bondi995 ↔ 1007By similarity
Disulfide bondi1010 ↔ 1019By similarity
Disulfide bondi1012 ↔ 1026By similarity
Disulfide bondi1028 ↔ 1037By similarity
Glycosylationi1031N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1040 ↔ 1053By similarity
Disulfide bondi1056 ↔ 1068By similarity
Glycosylationi1057N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi1058 ↔ 1075By similarity
Disulfide bondi1077 ↔ 1086By similarity
Disulfide bondi1089 ↔ 1099By similarity
Disulfide bondi1102 ↔ 1114By similarity
Disulfide bondi1104 ↔ 1130By similarity
Disulfide bondi1132 ↔ 1141By similarity
Disulfide bondi1144 ↔ 1159By similarity
Disulfide bondi1378 ↔ 1387By similarity
Disulfide bondi1416 ↔ 1425By similarity
Disulfide bondi1418 ↔ 1432By similarity
Disulfide bondi1435 ↔ 1444By similarity
Disulfide bondi1447 ↔ 1462By similarity
Disulfide bondi1465 ↔ 1480By similarity
Disulfide bondi1467 ↔ 1490By similarity
Disulfide bondi1493 ↔ 1502By similarity
Disulfide bondi1505 ↔ 1520By similarity
Disulfide bondi1523 ↔ 1535By similarity
Disulfide bondi1525 ↔ 1542By similarity
Disulfide bondi1544 ↔ 1553By similarity
Disulfide bondi1556 ↔ 1567By similarity
Disulfide bondi1570InterchainCurated
Disulfide bondi1574InterchainCurated
Glycosylationi1593N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1610N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1696N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1806N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1897N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1912N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi1916N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2013N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2024N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2041N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2122N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2236N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2298 ↔ 2324By similarity
Glycosylationi2356N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2431N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2474N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2491 ↔ 2517By similarity
Glycosylationi2547N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2554N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi2644N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2679 ↔ 2706By similarity
Glycosylationi2889N-linked (GlcNAc...) asparagineSequence analysis1
Disulfide bondi2905 ↔ 2930By similarity
Disulfide bondi3083 ↔ 3115By similarity

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

The CPTAC Assay portal

More...
CPTACi
non-CPTAC-3655
non-CPTAC-3835

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q60675

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q60675

PeptideAtlas

More...
PeptideAtlasi
Q60675

PRoteomics IDEntifications database

More...
PRIDEi
Q60675

PTM databases

GlyConnect protein glycosylation platform

More...
GlyConnecti
2456

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q60675

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q60675

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000019899 Expressed in 209 organ(s), highest expression level in sciatic nerve

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q60675 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q60675 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Alpha-2 is a subunit of laminin-2 (laminin-211 or merosin), laminin-4 (laminin-221 or S-merosin) and laminin-12 (laminin-213).

Interacts with FBLN1, FBLN2 and NID2.

1 Publication

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
201097, 1 interactor

ComplexPortal: manually curated resource of macromolecular complexes

More...
ComplexPortali
CPX-3009 Laminin-211 complex
CPX-3011 Laminin-221 complex
CPX-3018 Laminin-213 complex

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
Q60675

Protein interaction database and analysis system

More...
IntActi
Q60675, 1 interactor

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000090304

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
Q60675 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

13118
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q60675

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...
EvolutionaryTracei
Q60675

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini31 – 282Laminin N-terminalPROSITE-ProRule annotationAdd BLAST252
Domaini283 – 339Laminin EGF-like 1PROSITE-ProRule annotationAdd BLAST57
Domaini340 – 409Laminin EGF-like 2PROSITE-ProRule annotationAdd BLAST70
Domaini410 – 464Laminin EGF-like 3PROSITE-ProRule annotationAdd BLAST55
Domaini465 – 513Laminin EGF-like 4PROSITE-ProRule annotationAdd BLAST49
Domaini514 – 523Laminin EGF-like 5; first partPROSITE-ProRule annotation10
Domaini527 – 719Laminin IV type A 1PROSITE-ProRule annotationAdd BLAST193
Domaini720 – 752Laminin EGF-like 5; second partPROSITE-ProRule annotationAdd BLAST33
Domaini753 – 802Laminin EGF-like 6PROSITE-ProRule annotationAdd BLAST50
Domaini803 – 860Laminin EGF-like 7PROSITE-ProRule annotationAdd BLAST58
Domaini861 – 913Laminin EGF-like 8PROSITE-ProRule annotationAdd BLAST53
Domaini914 – 962Laminin EGF-like 9PROSITE-ProRule annotationAdd BLAST49
Domaini963 – 1009Laminin EGF-like 10PROSITE-ProRule annotationAdd BLAST47
Domaini1010 – 1055Laminin EGF-like 11PROSITE-ProRule annotationAdd BLAST46
Domaini1056 – 1101Laminin EGF-like 12PROSITE-ProRule annotationAdd BLAST46
Domaini1102 – 1161Laminin EGF-like 13PROSITE-ProRule annotationAdd BLAST60
Domaini1162 – 1171Laminin EGF-like 14; first partPROSITE-ProRule annotation10
Domaini1172 – 1375Laminin IV type A 2PROSITE-ProRule annotationAdd BLAST204
Domaini1376 – 1415Laminin EGF-like 14; second partPROSITE-ProRule annotationAdd BLAST40
Domaini1416 – 1464Laminin EGF-like 15PROSITE-ProRule annotationAdd BLAST49
Domaini1465 – 1522Laminin EGF-like 16PROSITE-ProRule annotationAdd BLAST58
Domaini1523 – 1569Laminin EGF-like 17PROSITE-ProRule annotationAdd BLAST47
Domaini2141 – 2324Laminin G-like 1PROSITE-ProRule annotationAdd BLAST184
Domaini2336 – 2517Laminin G-like 2PROSITE-ProRule annotationAdd BLAST182
Domaini2522 – 2706Laminin G-like 3PROSITE-ProRule annotationAdd BLAST185
Domaini2759 – 2930Laminin G-like 4PROSITE-ProRule annotationAdd BLAST172
Domaini2929 – 3115Laminin G-like 5PROSITE-ProRule annotationAdd BLAST187

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1570 – 2140Domain II and IAdd BLAST571

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1662 – 1863Sequence analysisAdd BLAST202
Coiled coili1923 – 2146Sequence analysisAdd BLAST224

<p>This subsection of the ‘Family and domains’ section provides general information on the biological role of a domain. The term ‘domain’ is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.
Domains VI, IV and G are globular.

Keywords - Domaini

Coiled coil, Laminin EGF-like domain, Repeat, Signal

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410KCXA Eukaryota
COG0419 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000155362

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000293201

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q60675

KEGG Orthology (KO)

More...
KOi
K05637

Database of Orthologous Groups

More...
OrthoDBi
128982at2759

TreeFam database of animal gene trees

More...
TreeFami
TF335359

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.120.1490, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR009030 Growth_fac_rcpt_cys_sf
IPR009254 Laminin_aI
IPR010307 Laminin_dom_II
IPR002049 Laminin_EGF
IPR001791 Laminin_G
IPR000034 Laminin_IV
IPR008211 Laminin_N
IPR038684 Laminin_N_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00052 Laminin_B, 2 hits
PF00053 Laminin_EGF, 16 hits
PF00054 Laminin_G_1, 4 hits
PF02210 Laminin_G_2, 1 hit
PF06008 Laminin_I, 1 hit
PF06009 Laminin_II, 1 hit
PF00055 Laminin_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 11 hits
SM00180 EGF_Lam, 16 hits
SM00281 LamB, 2 hits
SM00282 LamG, 5 hits
SM00136 LamNT, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49899 SSF49899, 5 hits
SSF57184 SSF57184, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00022 EGF_1, 11 hits
PS01186 EGF_2, 3 hits
PS01248 EGF_LAM_1, 14 hits
PS50027 EGF_LAM_2, 16 hits
PS50025 LAM_G_DOMAIN, 5 hits
PS51115 LAMININ_IVA, 2 hits
PS51117 LAMININ_NTER, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

Q60675-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPAATAGILL LLLLGTLEGS QTQRRQSQAH QQRGLFPAVL NLASNALITT
60 70 80 90 100
NATCGEKGPE MYCKLVEHVP GQPVRNPQCR ICNQNSSNPY QRHPITNAID
110 120 130 140 150
GKNTWWQSPS IKNGVEYHYV TITLDLQQVF QIAYVIVKAA NSPRPGNWIL
160 170 180 190 200
ERSLDDVEYK PWQYHAVTDT ECLTLYNIYP RTGPPSYAKD DEVICTSFYS
210 220 230 240 250
KIHPLENGEI HISLINGRPS ADDPSPELLE FTSARYIRLR FQRIRTLNAD
260 270 280 290 300
LMMFAHKDPR EIDPIVTRRY YYSVKDISVG GMCICYGHAR ACPLDPATNK
310 320 330 340 350
SRCECEHNTC GESCDRCCPG FHQKPWRAGT FLTKSECEAC NCHGKAEECY
360 370 380 390 400
YDETVASRNL SLNIHGKYIG GGVCINCTHN TAGINCETCV DGFFRPKGVS
410 420 430 440 450
PNYPRPCQPC HCDPTGSLSE VCVKDEKYAQ RGLKPGSCHC KTGFGGVNCD
460 470 480 490 500
RCVRGYHGYP DCQPCNCSGL GSTNEDPCVG PCSCKENVEG EDCSRCKSGF
510 520 530 540 550
FNLQEDNQKG CEECFCSGVS NRCQSSYWTY GNIQDMRGWY LTDLSGRIRM
560 570 580 590 600
APQLDNPDSP QQISISNSEA RKSLLDGYYW SAPPPYLGNR LPAVGGQLSF
610 620 630 640 650
TISYDLEEEE DDTEKILQLM IIFEGNDLRI STAYKEVYLE PSEEHIEEVS
660 670 680 690 700
LKEEAFTIHG TNLPVTRKDF MIVLTNLERV LMQITYNLGM DAIFRLSSVN
710 720 730 740 750
LESAVPYPTD RRIATDVEVC QCPPGYSGSS CETCWPRHRR VNGTIFGGIC
760 770 780 790 800
EPCQCFAHAE ACDDITGECL NCKDHTGGPY CNECLPGFYG DPTRGSPEDC
810 820 830 840 850
QPCACPLNIP SNNFSPTCHL DRSLGLICDE CPIGYTGPRC ERCAEGYFGQ
860 870 880 890 900
PSIPGGSCQP CQCNDNLDYS IPGSCDSLSG SCLICKPGTT GRYCELCADG
910 920 930 940 950
YFGDAVNAKN CQPCRCNING SFSEICHTRT GQCECRPNVQ GRHCDECKPE
960 970 980 990 1000
TFGLQLGRGC LPCNCNSFGS KSFDCEASGQ CWCQPGVAGK KCDRCAHGYF
1010 1020 1030 1040 1050
NFQEGGCIAC DCSHLGNNCD PKTGQCICPP NTTGEKCSEC LPNTWGHSIV
1060 1070 1080 1090 1100
TGCKVCNCST VGSLASQCNV NTGQCSCHPK FSGMKCSECS RGHWNYPLCT
1110 1120 1130 1140 1150
LCDCFLPGTD ATTCDLETRK CSCSDQTGQC SCKVNVEGVH CDRCRPGKFG
1160 1170 1180 1190 1200
LDAKNPLGCS SCYCFGVTSQ CSEAKGLIRT WVTLSDEQTI LPLVDEALQH
1210 1220 1230 1240 1250
TTTKGIAFQK PEIVAKMDEV RQELHLEPFY WKLPQQFEGK KLMAYGGKLK
1260 1270 1280 1290 1300
YAIYFEARDE TGFATYKPQV IIRGGTPTHA RIITRHMAAP LIGQLTRHEI
1310 1320 1330 1340 1350
EMTEKEWKYY GDDPRISRTV TREDFLDILY DIHYILIKAT YGNVVRQSRI
1360 1370 1380 1390 1400
SEISMEVAEP GHVLAGSPPA HLIERCDCPP GYSGLSCETC APGFYRLRSE
1410 1420 1430 1440 1450
PGGRTPGPTL GTCVPCQCNG HSSQCDPETS VCQNCQHHTA GDFCERCALG
1460 1470 1480 1490 1500
YYGIVRGLPN DCQPCACPLI SPSNNFSPSC VLEGLEDYRC TACPRGYEGQ
1510 1520 1530 1540 1550
YCERCAPGYT GSPSSPGGSC QECECDPYGS LPVPCDRVTG LCTCRPGATG
1560 1570 1580 1590 1600
RKCDGCEHWH AREGAECVFC GDECTGLLLG DLARLEQMTM NINLTGPLPA
1610 1620 1630 1640 1650
PYKILYGLEN TTQELKHLLS PQRAPERLIQ LAEGNVNTLV METNELLTRA
1660 1670 1680 1690 1700
TKVTADGEQT GQDAERTNSR AESLEEFIKG LVQDAEAINE KAVQLNETLG
1710 1720 1730 1740 1750
NQDKTAERNL EELQKEIDRM LKELRSKDLQ TQKEVAEDEL VAAEGLLKRV
1760 1770 1780 1790 1800
NKLFGEPRAQ NEDMEKDLQQ KLAEYKNKLD DAWDLLREAT DKTRDANRLS
1810 1820 1830 1840 1850
AANQKNMTIL ETKKEAIEGS KRQIENTLKE GNDILDEANR LLGEINSVID
1860 1870 1880 1890 1900
YVDDIKTKLP PMSEELSDKI DDLAQEIKDR RLAEKVFQAE SHAAQLNDSS
1910 1920 1930 1940 1950
AVLDGILDEA KNISFNATAA FRAYSNIKDY IDEAEKVARE AKELAQGATK
1960 1970 1980 1990 2000
LATSPQGLLK EDAKGSLQKS FRILNEAKKL ANDVKGNHND LNDLKTRLET
2010 2020 2030 2040 2050
ADLRNSGLLG ALNDTMDKLS AITNDTAAKL QAVKEKAREA NDTAKAVLAQ
2060 2070 2080 2090 2100
VKDLHQNLDG LKQNYNKLAD SVAKTNAVVK DPSKNKIIAD AGTSVRNLEQ
2110 2120 2130 2140 2150
EADRLIDKLK PIKELEDNLK KNISEIKELI NQARKQANSI KVSVSSGGDC
2160 2170 2180 2190 2200
VRTYRPEIKK GSYNNIVVHV KTAVADNLLF YLGSAKFIDF LAIEMRKGKV
2210 2220 2230 2240 2250
SFLWDVGSGV GRVEYPDLTI DDSYWYRIEA SRTGRNGSIS VRALDGPKAS
2260 2270 2280 2290 2300
MVPSTYHSVS PPGYTILDVD ANAMLFVGGL TGKIKKADAV RVITFTGCMG
2310 2320 2330 2340 2350
ETYFDNKPIG LWNFREKEGD CKGCTVSPQV EDSEGTIQFD GEGYALVSRP
2360 2370 2380 2390 2400
IRWYPNISTV MFKFRTFSSS ALLMYLATRD LKDFMSVELS DGHVKVSYDL
2410 2420 2430 2440 2450
GSGMTSVVSN QNHNDGKWKA FTLSRIQKQA NISIVDIDSN QEENVATSSS
2460 2470 2480 2490 2500
GNNFGLDLKA DDKIYFGGLP TLRNLSMKAR PEVNVKKYSG CLKDIEISRT
2510 2520 2530 2540 2550
PYNILSSPDY VGVTKGCSLE NVYTVSFPKP GFVELAAVSI DVGTEINLSF
2560 2570 2580 2590 2600
STRNESGIIL LGSGGTLTPP RRKRRQTTQA YYAIFLNKGR LEVHLSSGTR
2610 2620 2630 2640 2650
TMRKIVIKPE PNLFHDGREH SVHVERTRGI FTVQIDEDRR HMQNLTEEQP
2660 2670 2680 2690 2700
IEVKKLFVGG APPEFQPSPL RNIPAFQGCV WNLVINSIPM DFAQPIAFKN
2710 2720 2730 2740 2750
ADIGRCTYQK PREDESEAVP AEVIVQPQPV PTPAFPFPAP TMVHGPCVAE
2760 2770 2780 2790 2800
SEPALLTGSK QFGLSRNSHI AIAFDDTKVK NRLTIELEVR TEAESGLLFY
2810 2820 2830 2840 2850
MARINHADFA TVQLRNGFPY FSYDLGSGDT STMIPTKIND GQWHKIKIVR
2860 2870 2880 2890 2900
VKQEGILYVD DASSQTISPK KADILDVVGI LYVGGLPINY TTRRIGPVTY
2910 2920 2930 2940 2950
SLDGCVRNLH MEQAPVDLDQ PTSSFHVGTC FANAESGTYF DGTGFAKAVG
2960 2970 2980 2990 3000
GFKVGLDLLV EFEFRTTRPT GVLLGVSSQK MDGMGIEMID EKLMFHVDNG
3010 3020 3030 3040 3050
AGRFTAIYDA GIPGHMCNGQ WHKVTAKKIK NRLELVVDGN QVDAQSPNSA
3060 3070 3080 3090 3100
STSADTNDPV FVGGFPGGLN QFGLTTNIRF RGCIRSLKLT KGTGKPLEVN
3110
FAKALELRGV QPVSCPTT
Length:3,118
Mass (Da):343,815
Last modified:October 16, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iCCD31C71B1E0DFD4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A1W2P7N3A0A1W2P7N3_MOUSE
Laminin subunit alpha-2
Lama2
1,127Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A087WRP2A0A087WRP2_MOUSE
Laminin subunit alpha-2
Lama2
1,349Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A5F8MPG7A0A5F8MPG7_MOUSE
Laminin subunit alpha-2
Lama2
256Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAC52165 differs from that shown. Reason: Frameshift.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti616I → L in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti646I → V in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti678 – 682ERVLM → GEILI in AAC52165 (PubMed:7795883).Curated5
Sequence conflicti704A → P in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti853I → V in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti908A → T in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti917N → D in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti925I → D in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti1694Q → K in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti1840R → Q in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2205D → I in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2214 – 2215EY → GF in AAC52165 (PubMed:7795883).Curated2
Sequence conflicti2523Y → N in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2642M → I in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2729P → S in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2739A → V in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2773A → V in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2802A → G in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2810A → G in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2820Y → F in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2829 – 2831DTS → STR in AAC52165 (PubMed:7795883).Curated3
Sequence conflicti2878V → G in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2946A → G in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2953K → I in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti2976V → I in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti3011G → E in AAC52165 (PubMed:7795883).Curated1
Sequence conflicti3022H → Y in AAC52165 (PubMed:7795883).Curated1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
U12147 mRNA Translation: AAC52165.1 Frameshift.
AC101709 Genomic DNA No translation available.
AC152982 Genomic DNA No translation available.
AC153800 Genomic DNA No translation available.
AC155942 Genomic DNA No translation available.
AC167232 Genomic DNA No translation available.
AC171406 Genomic DNA No translation available.
X69869 mRNA Translation: CAA49502.1
S75315 mRNA Translation: AAB33573.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS48526.1

Protein sequence database of the Protein Information Resource

More...
PIRi
I49077 S53868

NCBI Reference Sequences

More...
RefSeqi
NP_032507.2, NM_008481.2

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000092639; ENSMUSP00000090304; ENSMUSG00000019899

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
16773

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:16773

UCSC genome browser

More...
UCSCi
uc007esf.2 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12147 mRNA Translation: AAC52165.1 Frameshift.
AC101709 Genomic DNA No translation available.
AC152982 Genomic DNA No translation available.
AC153800 Genomic DNA No translation available.
AC155942 Genomic DNA No translation available.
AC167232 Genomic DNA No translation available.
AC171406 Genomic DNA No translation available.
X69869 mRNA Translation: CAA49502.1
S75315 mRNA Translation: AAB33573.1
CCDSiCCDS48526.1
PIRiI49077 S53868
RefSeqiNP_032507.2, NM_008481.2

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1DYKX-ray2.00A2730-3118[»]
1OKQX-ray2.80A2730-3118[»]
1QU0X-ray2.35A/B/C/D2932-3118[»]
2WJSX-ray2.80A2136-2749[»]
5IK4X-ray1.27A2730-3118[»]
5IK5X-ray1.39A2730-3118[»]
5IK7X-ray2.00A/B2742-3118[»]
5IK8X-ray2.00A/B2742-3118[»]
SMRiQ60675
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi201097, 1 interactor
ComplexPortaliCPX-3009 Laminin-211 complex
CPX-3011 Laminin-221 complex
CPX-3018 Laminin-213 complex
CORUMiQ60675
IntActiQ60675, 1 interactor
STRINGi10090.ENSMUSP00000090304

Protein family/group databases

UniLectiniQ60675

PTM databases

GlyConnecti2456
iPTMnetiQ60675
PhosphoSitePlusiQ60675

Proteomic databases

CPTACinon-CPTAC-3655
non-CPTAC-3835
MaxQBiQ60675
PaxDbiQ60675
PeptideAtlasiQ60675
PRIDEiQ60675

Genome annotation databases

EnsembliENSMUST00000092639; ENSMUSP00000090304; ENSMUSG00000019899
GeneIDi16773
KEGGimmu:16773
UCSCiuc007esf.2 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
3908
MGIiMGI:99912 Lama2

Phylogenomic databases

eggNOGiENOG410KCXA Eukaryota
COG0419 LUCA
GeneTreeiENSGT00940000155362
HOGENOMiHOG000293201
InParanoidiQ60675
KOiK05637
OrthoDBi128982at2759
TreeFamiTF335359

Enzyme and pathway databases

ReactomeiR-MMU-3000157 Laminin interactions
R-MMU-8874081 MET activates PTK2 signaling

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Lama2 mouse
EvolutionaryTraceiQ60675

Protein Ontology

More...
PROi
PR:Q60675
RNActiQ60675 protein

The Stanford Online Universal Resource for Clones and ESTs

More...
SOURCEi
Search...

Gene expression databases

BgeeiENSMUSG00000019899 Expressed in 209 organ(s), highest expression level in sciatic nerve
ExpressionAtlasiQ60675 baseline and differential
GenevisibleiQ60675 MM

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR013320 ConA-like_dom_sf
IPR000742 EGF-like_dom
IPR009030 Growth_fac_rcpt_cys_sf
IPR009254 Laminin_aI
IPR010307 Laminin_dom_II
IPR002049 Laminin_EGF
IPR001791 Laminin_G
IPR000034 Laminin_IV
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
PfamiView protein in Pfam
PF00052 Laminin_B, 2 hits
PF00053 Laminin_EGF, 16 hits
PF00054 Laminin_G_1, 4 hits
PF02210 Laminin_G_2, 1 hit
PF06008 Laminin_I, 1 hit
PF06009 Laminin_II, 1 hit
PF00055 Laminin_N, 1 hit
SMARTiView protein in SMART
SM00181 EGF, 11 hits
SM00180 EGF_Lam, 16 hits
SM00281 LamB, 2 hits
SM00282 LamG, 5 hits
SM00136 LamNT, 1 hit
SUPFAMiSSF49899 SSF49899, 5 hits
SSF57184 SSF57184, 1 hit
PROSITEiView protein in PROSITE
PS00022 EGF_1, 11 hits
PS01186 EGF_2, 3 hits
PS01248 EGF_LAM_1, 14 hits
PS50027 EGF_LAM_2, 16 hits
PS50025 LAM_G_DOMAIN, 5 hits
PS51115 LAMININ_IVA, 2 hits
PS51117 LAMININ_NTER, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiLAMA2_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q60675
Secondary accession number(s): F8VQ43, Q05003, Q64061
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: October 16, 2013
Last modified: December 11, 2019
This is version 193 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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