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Protein

Zinc finger protein 30

Gene

Zfp30

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri172 – 194C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 5; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri508 – 530C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 30
Short name:
Zfp-30
Gene namesi
Name:Zfp30
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:99178 Zfp30

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000472921 – 533Zinc finger protein 30Add BLAST533

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei75Asymmetric dimethylarginineCombined sources1
Cross-linki155Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity

Keywords - PTMi

Isopeptide bond, Methylation, Ubl conjugation

Proteomic databases

PaxDbiQ60585
PRIDEiQ60585

PTM databases

iPTMnetiQ60585
PhosphoSitePlusiQ60585

Expressioni

Gene expression databases

CleanExiMM_ZFP30

Interactioni

Protein-protein interaction databases

BioGridi204656, 1 interactor
STRINGi10090.ENSMUSP00000032803

Structurei

3D structure databases

ProteinModelPortaliQ60585
SMRiQ60585
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 78KRABPROSITE-ProRule annotationAdd BLAST73

Sequence similaritiesi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri172 – 194C2H2-type 1PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri200 – 222C2H2-type 2PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri228 – 250C2H2-type 3PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri256 – 278C2H2-type 4PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri284 – 306C2H2-type 5; degeneratePROSITE-ProRule annotationAdd BLAST23
Zinc fingeri312 – 334C2H2-type 6PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri340 – 362C2H2-type 7PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri368 – 390C2H2-type 8PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri396 – 418C2H2-type 9PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri424 – 446C2H2-type 10PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri452 – 474C2H2-type 11PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri480 – 502C2H2-type 12PROSITE-ProRule annotationAdd BLAST23
Zinc fingeri508 – 530C2H2-type 13PROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOVERGENiHBG018163
InParanoidiQ60585
KOiK09228

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 13 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 13 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q60585-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAHSTVMFRD VAVGFSQEEW ECLSAYERDL YRDVMLENYS HLVSLAGCSI
60 70 80 90 100
SKPDVITLLE QGKEPWMIVR AEKRRWSRDL ESRYSSNGLL PEKNTYEINL
110 120 130 140 150
SPWEIMGRIQ RRGPEDSLLG KDFEYKIYEE QENSHRVYFR HVIKTTSGKR
160 170 180 190 200
PRYRKRTPVS LYQKTPNGEK PYECGECGKA FKVRQQLTFH QRIHTGEKPY
210 220 230 240 250
ECKECGKAFR QCAHLSRHQR IHASDKLYEC KKCAKIFTCS SDLRGHQRSH
260 270 280 290 300
VGEKPYDCKE CGKAFRVRGQ LMLHQRIHTG EKPYACTECG KSFRQVAHLT
310 320 330 340 350
RHQRLNSGSS RHECKECGRA FLCSTGLRLH HKLHTGEKPY DCKECGKAFR
360 370 380 390 400
VRQQLTLHER IHTGEKPFDC KECGKTFSRG YHLTLHQRIH TGEKPYECKE
410 420 430 440 450
CRKFFRRYSE LISHQGIHIG EKPYDCKECG KAFRLFSQLT QHQSIHFGEK
460 470 480 490 500
PYKCMECEKT FRLLSQLTQH QSIHTGEKPY DCKECGKAFR LHSSLIQHQR
510 520 530
IHSGEKPYKC TECKKAFRQH SHLTYHQRIH KNL
Length:533
Mass (Da):62,769
Last modified:May 24, 2005 - v2
Checksum:i0058748909A30CC3
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q78FW7Q78FW7_MOUSE
Brain specifically expressed BSG3
Zfp30 Bsg3
548Annotation score:
D3Z614D3Z614_MOUSE
Zinc finger protein 30
Zfp30
467Annotation score:

Sequence cautioni

The sequence CAA82913 differs from that shown. Reason: Erroneous initiation.Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z30174 mRNA Translation: CAA82913.1 Different initiation.
AK014064 mRNA Translation: BAB29138.2
PIRiI48208 S42077
RefSeqiNP_038733.1, NM_013705.1
UniGeneiMm.292690

Genome annotation databases

GeneIDi22693
KEGGimmu:22693
UCSCiuc009gcc.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z30174 mRNA Translation: CAA82913.1 Different initiation.
AK014064 mRNA Translation: BAB29138.2
PIRiI48208 S42077
RefSeqiNP_038733.1, NM_013705.1
UniGeneiMm.292690

3D structure databases

ProteinModelPortaliQ60585
SMRiQ60585
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi204656, 1 interactor
STRINGi10090.ENSMUSP00000032803

PTM databases

iPTMnetiQ60585
PhosphoSitePlusiQ60585

Proteomic databases

PaxDbiQ60585
PRIDEiQ60585

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi22693
KEGGimmu:22693
UCSCiuc009gcc.1 mouse

Organism-specific databases

CTDi22835
MGIiMGI:99178 Zfp30

Phylogenomic databases

eggNOGiKOG1721 Eukaryota
COG5048 LUCA
HOVERGENiHBG018163
InParanoidiQ60585
KOiK09228

Miscellaneous databases

PROiPR:Q60585
SOURCEiSearch...

Gene expression databases

CleanExiMM_ZFP30

Family and domain databases

CDDicd07765 KRAB_A-box, 1 hit
InterProiView protein in InterPro
IPR001909 KRAB
IPR036051 KRAB_dom_sf
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
PfamiView protein in Pfam
PF01352 KRAB, 1 hit
PF00096 zf-C2H2, 11 hits
SMARTiView protein in SMART
SM00349 KRAB, 1 hit
SM00355 ZnF_C2H2, 13 hits
SUPFAMiSSF109640 SSF109640, 1 hit
SSF57667 SSF57667, 7 hits
PROSITEiView protein in PROSITE
PS50805 KRAB, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 12 hits
PS50157 ZINC_FINGER_C2H2_2, 13 hits
ProtoNetiSearch...

Entry informationi

Entry nameiZFP30_MOUSE
AccessioniPrimary (citable) accession number: Q60585
Secondary accession number(s): Q9CRV9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2005
Last sequence update: May 24, 2005
Last modified: November 7, 2018
This is version 134 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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