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Entry version 143 (08 May 2019)
Sequence version 2 (06 Feb 2013)
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Protein
Submitted name:

Uncharacterized protein

Gene

mec-1

Organism
Caenorhabditis elegans
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • calcium ion binding Source: InterPro
  • serine-type endopeptidase inhibitor activity Source: GO_Central

GO - Biological processi

  • detection of mechanical stimulus involved in sensory perception of touch Source: UniProtKB
  • extracellular structure organization Source: WormBase
  • mechanosensory behavior Source: WormBase
  • response to mechanical stimulus Source: WormBase

Protein family/group databases

MEROPS protease database

More...
MEROPSi
I02.972

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:mec-1Imported
ORF Names:CELE_T07H8.4Imported, T07H8.4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiCaenorhabditis elegansImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri6239 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditinaRhabditomorphaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001940 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome V

Organism-specific databases

WormBase

More...
WormBasei
T07H8.4a ; CE48078 ; WBGene00003165 ; mec-1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5ZR42

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
WBGene00003165 Expressed in 4 organ(s), highest expression level in multi-cellular organism

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5ZR42 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
6239.T07H8.4a.1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5ZR42

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini46 – 96BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51
Domaini202 – 240EGF-likeInterPro annotationAdd BLAST39
Domaini246 – 303BPTI/Kunitz inhibitorInterPro annotationAdd BLAST58
Domaini411 – 471BPTI/Kunitz inhibitorInterPro annotationAdd BLAST61
Domaini615 – 675BPTI/Kunitz inhibitorInterPro annotationAdd BLAST61
Domaini859 – 915BPTI/Kunitz inhibitorInterPro annotationAdd BLAST57
Domaini1104 – 1160BPTI/Kunitz inhibitorInterPro annotationAdd BLAST57
Domaini1254 – 1311BPTI/Kunitz inhibitorInterPro annotationAdd BLAST58
Domaini1323 – 1379BPTI/Kunitz inhibitorInterPro annotationAdd BLAST57
Domaini1390 – 1446BPTI/Kunitz inhibitorInterPro annotationAdd BLAST57
Domaini1458 – 1514BPTI/Kunitz inhibitorInterPro annotationAdd BLAST57
Domaini1534 – 1584BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51
Domaini1597 – 1654BPTI/Kunitz inhibitorInterPro annotationAdd BLAST58
Domaini1674 – 1728BPTI/Kunitz inhibitorInterPro annotationAdd BLAST55
Domaini1740 – 1790BPTI/Kunitz inhibitorInterPro annotationAdd BLAST51
Domaini1798 – 1849BPTI/Kunitz inhibitorInterPro annotationAdd BLAST52

Keywords - Domaini

EGF-like domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG4295 Eukaryota
ENOG410XQNP LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000272637

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5ZR42

Identification of Orthologs from Complete Genome Data

More...
OMAi
CQWICER

Database of Orthologous Groups

More...
OrthoDBi
35188at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00109 KU, 6 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.410.10, 15 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF07645 EGF_CA, 1 hit
PF00014 Kunitz_BPTI, 13 hits

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00759 BASICPTASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00181 EGF, 2 hits
SM00179 EGF_CA, 1 hit
SM00131 KU, 15 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57362 SSF57362, 15 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00010 ASX_HYDROXYL, 1 hit
PS00280 BPTI_KUNITZ_1, 4 hits
PS50279 BPTI_KUNITZ_2, 15 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 1 hit
PS01187 EGF_CA, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 9 potential isoforms that are computationally mapped.Show allAlign All

Q5ZR42-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHLFLLFIPH VIAVKDLAWY SANPVLSSSH PVGPAAIQAA TAIDFCQLPV
60 70 80 90 100
DTGKCSQQLV RYYYDAAVDE CKRFTFSGCG GNSNRFMRRA HCRNRCVKQP
110 120 130 140 150
NKPEVQELKH RRTVTSTTST PFQTVNEEST VEPSATKRLP VTLPVKKLEL
160 170 180 190 200
VQVRIFNKTE SSFQSGHGNG LCQDCDPLYG TCLDGKCGCM KGFRSLGKVC
210 220 230 240 250
IDLNECDNGA VCGPNARCVN EIGSFQCVCD AGFSTDGDCK IGQEACMDEF
260 270 280 290 300
DVNLTEEDCN NGKQEIKYYY DADSVQCKQF FYGGCKTTSR NFFADLQTCD
310 320 330 340 350
VICVSNQRDY LKSKGQSLSH HPVLEISSDL NNGNDLKSNH YKIDLFSSPS
360 370 380 390 400
SPVTPNRPLS ADDWPLKPIT LKPALNLDFS QGKTKSTAEK HKEADDAEIL
410 420 430 440 450
VHQLTPEHNS CDLKFEPVLR EECISADWAE KFFWNSEFKD CEPFWYDSSC
460 470 480 490 500
DPRDRAGKNF FETFEDCKNK CDGVQSQYVV PITTVPDEQS KIEEVETSET
510 520 530 540 550
PGIVDETTTT AAPEEESEEN GFFFKVKPQN YLEDVLSSET EETQHYGFNP
560 570 580 590 600
NEFLKQNSQN QKPTEITEIL RILPAQTEHD EASELKKEDK IEHDILEHLK
610 620 630 640 650
NKEPTEKVLS TPSTCDLEYD DALRNECTSA DWTELYYWNA QFKECEAFWY
660 670 680 690 700
DSSCGDQDFS KKNLFKNFDD CNNQCVKKIG EALKKMDPET TTTTSTTTTT
710 720 730 740 750
TTAPTTTKME EPKRSNYKQS DPLNLILNKA LNPDESSELP EKFPPAHEQG
760 770 780 790 800
FVNFAIKSEV TATTKFDRLK YMAEFRKKLL ALPDNFSTTP KQSSPTSSPT
810 820 830 840 850
TTRMRSPSTH KSTVSQATKT ASSTPQSPST TTSFDDFVEK EKKTVLETIK
860 870 880 890 900
ILDRPEDLCD EPLHPKLEED CKNDQWEIQW FFNSDRGACK SFWYGGCEIE
910 920 930 940 950
SRNFFPDHAN CRHSCAHKYA TPASFSSKVY IPPGELSTPV PPRKDRLTTS
960 970 980 990 1000
LKLTYPHSED LFPSEEHSTV VELDGNFQRT EKQERIRLFP TKTFRPRAPT
1010 1020 1030 1040 1050
PTASNIVNVS EGEKTETAPA FYSHIDRVVH DMKTGEHPGY TKPEEFVRRI
1060 1070 1080 1090 1100
ESASNDYIKY DLQKPDVVTI IDKSPPTVPS RKERTERTEV TTKLPSTRSI
1110 1120 1130 1140 1150
NDPCDDEYDP KWDEDCLGDT WVVRSYYDSK AEKCKAFWYG GCHTSSRNIW
1160 1170 1180 1190 1200
FDKETCRTSC AHKFPTDMPM YGGAQSSEVS AEILPSPQEE NSSKETSSSS
1210 1220 1230 1240 1250
SSSSSSNTAH ISPEHRFKVD LDQKFADVKR EHEGREDLAY SQMVQHPVTV
1260 1270 1280 1290 1300
SADCLEVYNA SLSKPCGDGK SWSNRYFYDK DTRSCRMFWS NGCFSSSKNN
1310 1320 1330 1340 1350
FDDLETCQWK CEGRHPQPAG KSCLDKFDER YLEDCRHGEF TNRFYFDHDR
1360 1370 1380 1390 1400
KKCVAFHWGG CQSKSQNFFA DMTVCQDLCE SPPRELTQAC LQPFDTTYET
1410 1420 1430 1440 1450
SCSAEKPQQY YYFDMSSGIC KMFWFGNCKG ENQNIFSTLE ACQWICERKR
1460 1470 1480 1490 1500
DERKPAICAD KFDTKYTESC GDSQWTEKWY FDQSSGDCSS FWWDECTSSS
1510 1520 1530 1540 1550
QNIFPDEKSC TSNCKHPGFE ISSKLATEES KFRCLEPVEI GSCQETYPAF
1560 1570 1580 1590 1600
YYDRASRTCR PFAYSGCGGN SNRFMTVSQC ENLCFAFNSM NEAEVDCHLP
1610 1620 1630 1640 1650
MHIGYGKNED SCLPQAGFRF YYDRNYGKCS QMWYLGCGGN ANNFYSYEIC
1660 1670 1680 1690 1700
QRTCSQSDVP RELERKTRAS SEVCFEPPGD RGICGKNSST NPLKRWTYGN
1710 1720 1730 1740 1750
QKCTSFTYSG CGGNRNRFAT QDICENTCNG LMNSNDPRIC SFSPDWGSCN
1760 1770 1780 1790 1800
QLRYVWFYNL TRGTCDQFLY GGCGGNPNRF DTFEICQKAC EVTGTDPCME
1810 1820 1830 1840 1850
SLDRGSWCEA MSNRYYFNKR ARQCKGFHYT GCGKSGNNFL TKEECQTKCE
1860 1870 1880 1890 1900
KRFPRAAPSK KKAKVKLPVG YSGAKPKDKT PMLRHINLNG NNQTYFKSEP
1910 1920 1930 1940 1950
QWMDYSSCYG YRYNVTGRDT ILNVHYCAIR GSADCISESY RSTEGEEYCN
1960 1970 1980 1990 2000
ILRPFLRGQN LYSFYFGLDS VNPMYRPKDG LSGRIQRKNE TIAAVLVLKA

NQCHEIC
Length:2,007
Mass (Da):228,416
Last modified:February 6, 2013 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iADC23A375335D366
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 9 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A5A8R1A5A8R1_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
954Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5ZR41Q5ZR41_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
1,685Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5ZR40Q5ZR40_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
2,006Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5ZR36Q5ZR36_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
1,818Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5ZR39Q5ZR39_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
1,995Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2KZ67H2KZ67_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
1,167Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H2KZ68H2KZ68_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
1,954Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A5A8R2A5A8R2_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
255Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5ZR35Q5ZR35_CAEEL
Uncharacterized protein
mec-1 CELE_T07H8.4, T07H8.4
1,604Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD66552.2

NCBI Reference Sequences

More...
RefSeqi
NP_741559.3, NM_171477.5

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
T07H8.4a.1; T07H8.4a.1; WBGene00003165
T07H8.4a.2; T07H8.4a.2; WBGene00003165

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
188259

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
cel:CELE_T07H8.4

UCSC genome browser

More...
UCSCi
T07H8.4a c. elegans

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX284605 Genomic DNA Translation: CCD66552.2
RefSeqiNP_741559.3, NM_171477.5

3D structure databases

SMRiQ5ZR42
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi6239.T07H8.4a.1

Protein family/group databases

MEROPSiI02.972

Proteomic databases

PaxDbiQ5ZR42

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiT07H8.4a.1; T07H8.4a.1; WBGene00003165
T07H8.4a.2; T07H8.4a.2; WBGene00003165
GeneIDi188259
KEGGicel:CELE_T07H8.4
UCSCiT07H8.4a c. elegans

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
188259
WormBaseiT07H8.4a ; CE48078 ; WBGene00003165 ; mec-1

Phylogenomic databases

eggNOGiKOG4295 Eukaryota
ENOG410XQNP LUCA
HOGENOMiHOG000272637
InParanoidiQ5ZR42
OMAiCQWICER
OrthoDBi35188at2759

Gene expression databases

BgeeiWBGene00003165 Expressed in 4 organ(s), highest expression level in multi-cellular organism
ExpressionAtlasiQ5ZR42 baseline and differential

Family and domain databases

CDDicd00109 KU, 6 hits
Gene3Di4.10.410.10, 15 hits
InterProiView protein in InterPro
IPR001881 EGF-like_Ca-bd_dom
IPR013032 EGF-like_CS
IPR000742 EGF-like_dom
IPR000152 EGF-type_Asp/Asn_hydroxyl_site
IPR018097 EGF_Ca-bd_CS
IPR002223 Kunitz_BPTI
IPR036880 Kunitz_BPTI_sf
IPR020901 Prtase_inh_Kunz-CS
PfamiView protein in Pfam
PF07645 EGF_CA, 1 hit
PF00014 Kunitz_BPTI, 13 hits
PRINTSiPR00759 BASICPTASE
SMARTiView protein in SMART
SM00181 EGF, 2 hits
SM00179 EGF_CA, 1 hit
SM00131 KU, 15 hits
SUPFAMiSSF57362 SSF57362, 15 hits
PROSITEiView protein in PROSITE
PS00010 ASX_HYDROXYL, 1 hit
PS00280 BPTI_KUNITZ_1, 4 hits
PS50279 BPTI_KUNITZ_2, 15 hits
PS01186 EGF_2, 1 hit
PS50026 EGF_3, 1 hit
PS01187 EGF_CA, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5ZR42_CAEEL
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5ZR42
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: February 6, 2013
Last modified: May 8, 2019
This is version 143 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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