UniProtKB - Q5ZMK0 (Q5ZMK0_CHICK)
Protein
Pept_C1 domain-containing protein
Gene
CTSO
Organism
Gallus gallus (Chicken)
Status
Functioni
GO - Molecular functioni
- cysteine-type endopeptidase activity Source: GO_Central
GO - Biological processi
- proteolysis involved in cellular protein catabolic process Source: GO_Central
Keywordsi
Molecular function | Hydrolase, Protease, Thiol proteaseARBA annotation |
Enzyme and pathway databases
Reactomei | R-GGA-2132295, MHC class II antigen presentation |
Protein family/group databases
MEROPSi | C01.035 |
Names & Taxonomyi
Protein namesi | Recommended name: Pept_C1 domain-containing proteinInterPro annotation |
Gene namesi | Name:CTSOImported ORF Names:RCJMB04_1m17Imported |
Organismi | Gallus gallus (Chicken)Imported |
Taxonomic identifieri | 9031 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus |
Proteomesi |
|
Subcellular locationi
Extracellular region or secreted
- extracellular space Source: GO_Central
Lysosome
- lysosome Source: GO_Central
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 20 | Sequence analysisAdd BLAST | 20 | |
ChainiPRO_5014205913 | 21 – 320 | Pept_C1 domain-containing proteinSequence analysisAdd BLAST | 300 |
Expressioni
Gene expression databases
Bgeei | ENSGALG00000009373, Expressed in liver and 12 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 107 – 319 | Pept_C1InterPro annotationAdd BLAST | 213 |
Sequence similaritiesi
Belongs to the peptidase C1 family.ARBA annotation
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG1542, Eukaryota |
GeneTreei | ENSGT00940000159253 |
HOGENOMi | CLU_012184_1_3_1 |
OMAi | FTPTWPR |
OrthoDBi | 1275401at2759 |
TreeFami | TF331594 |
Family and domain databases
CDDi | cd02248, Peptidase_C1A, 1 hit |
InterProi | View protein in InterPro IPR038765, Papain-like_cys_pep_sf IPR025661, Pept_asp_AS IPR000169, Pept_cys_AS IPR025660, Pept_his_AS IPR000668, Peptidase_C1A_C IPR039417, Peptidase_C1A_papain-like |
Pfami | View protein in Pfam PF00112, Peptidase_C1, 1 hit |
PRINTSi | PR00705, PAPAIN |
SMARTi | View protein in SMART SM00645, Pept_C1, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS00640, THIOL_PROTEASE_ASN, 1 hit PS00139, THIOL_PROTEASE_CYS, 1 hit PS00639, THIOL_PROTEASE_HIS, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5ZMK0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVLAFGLAL ACCLLRAADA AFAVPAGAAG RPPWDGGGRE EEAAALRESA
60 70 80 90 100
KRIRLLNSPS NDNGSAFYGK NQFSHLFPEE FKAIYLRSIP YKLPRYIKVP
110 120 130 140 150
KGEEKPLPKK FDWRDKKVIA EVRNQQTCGG CWAFSVVGGI ESAYAIKGHN
160 170 180 190 200
LEELSVQQVI DCSYSNYGCS GGSTITALSW LNQTKVKLVR DSEYTFKAQT
210 220 230 240 250
GLCHYFPHSD FGVSITGFAA YDFSGQEEEM MRVLVDWGPL AVTVDAVSWQ
260 270 280 290 300
DYLGGIIQYH CSSGKANHAV LITGFDTTGS IPYWIVQNSW GRTWGIDGYV
310 320
RVKIGSNVCG IADTVSSVFV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AADN05000018 Genomic DNA No translation available. AJ719384 mRNA Translation: CAG31043.1 |
RefSeqi | NP_001026300.1, NM_001031129.1 |
Genome annotation databases
Ensembli | ENSGALT00000015270; ENSGALP00000015254; ENSGALG00000009373 |
GeneIDi | 422410 |
KEGGi | gga:422410 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AADN05000018 Genomic DNA No translation available. AJ719384 mRNA Translation: CAG31043.1 |
RefSeqi | NP_001026300.1, NM_001031129.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9031.ENSGALP00000015254 |
Protein family/group databases
MEROPSi | C01.035 |
Genome annotation databases
Ensembli | ENSGALT00000015270; ENSGALP00000015254; ENSGALG00000009373 |
GeneIDi | 422410 |
KEGGi | gga:422410 |
Organism-specific databases
CTDi | 1519 |
Phylogenomic databases
eggNOGi | KOG1542, Eukaryota |
GeneTreei | ENSGT00940000159253 |
HOGENOMi | CLU_012184_1_3_1 |
OMAi | FTPTWPR |
OrthoDBi | 1275401at2759 |
TreeFami | TF331594 |
Enzyme and pathway databases
Reactomei | R-GGA-2132295, MHC class II antigen presentation |
Gene expression databases
Bgeei | ENSGALG00000009373, Expressed in liver and 12 other tissues |
Family and domain databases
CDDi | cd02248, Peptidase_C1A, 1 hit |
InterProi | View protein in InterPro IPR038765, Papain-like_cys_pep_sf IPR025661, Pept_asp_AS IPR000169, Pept_cys_AS IPR025660, Pept_his_AS IPR000668, Peptidase_C1A_C IPR039417, Peptidase_C1A_papain-like |
Pfami | View protein in Pfam PF00112, Peptidase_C1, 1 hit |
PRINTSi | PR00705, PAPAIN |
SMARTi | View protein in SMART SM00645, Pept_C1, 1 hit |
SUPFAMi | SSF54001, SSF54001, 1 hit |
PROSITEi | View protein in PROSITE PS00640, THIOL_PROTEASE_ASN, 1 hit PS00139, THIOL_PROTEASE_CYS, 1 hit PS00639, THIOL_PROTEASE_HIS, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5ZMK0_CHICK | |
Accessioni | Q5ZMK0Primary (citable) accession number: Q5ZMK0 Secondary accession number(s): F1P0K2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 23, 2004 |
Last sequence update: | November 23, 2004 | |
Last modified: | December 2, 2020 | |
This is version 108 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |