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Entry version 87 (26 Feb 2020)
Sequence version 1 (23 Nov 2004)
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Protein
Submitted name:

Uncharacterized protein

Gene

RCJMB04_1o14

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Protein family/group databases

MEROPS protease database

More...
MEROPSi
M16.005

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:RCJMB04_1o14Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiGallus gallus (Chicken)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9031 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini214 – 343Peptidase_M16InterPro annotationAdd BLAST130
Domaini369 – 553Peptidase_M16_CInterPro annotationAdd BLAST185
Domaini560 – 840Peptidase_M16_MInterPro annotationAdd BLAST281
Domaini846 – 1027Peptidase_M16_CInterPro annotationAdd BLAST182

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni12 – 105DisorderedSequence analysisAdd BLAST94
Regioni132 – 212DisorderedSequence analysisAdd BLAST81

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi77 – 92PolyampholyteSequence analysisAdd BLAST16
Compositional biasi136 – 202AcidicSequence analysisAdd BLAST67

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the peptidase M16 family.UniRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0959 Eukaryota
COG1025 LUCA

KEGG Orthology (KO)

More...
KOi
K01411

Database of Orthologous Groups

More...
OrthoDBi
1008844at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5ZMI8

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR011249 Metalloenz_LuxS/M16
IPR011765 Pept_M16_N
IPR001431 Pept_M16_Zn_BS
IPR007863 Peptidase_M16_C
IPR032632 Peptidase_M16_M

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00675 Peptidase_M16, 1 hit
PF05193 Peptidase_M16_C, 2 hits
PF16187 Peptidase_M16_M, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF63411 SSF63411, 4 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00143 INSULINASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5ZMI8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRRLARRLAA AFARRGRAAR PGAERGRPPP PVRGSARPLW RCAAAAMPGR
60 70 80 90 100
NKATSNYGCP ELTMGQQAGV SGRDAGGRSP HGEEEERGEL GGNLGDPDIV
110 120 130 140 150
KSPSDPKQYR YIKLQNGLCA LLISDLNYLD GAPSTLSSEE EEEEEDDDDE
160 170 180 190 200
SEEESDEDDS GAEIEDGREG FDEDCDEGDE DDDDEEDNED FNDPDDSELE
210 220 230 240 250
ELAEKEETRK RGCTEKQSAA ALCVAVGSFS DPEDLPGLAH FLEHMVFMGS
260 270 280 290 300
LKYPDENGFD AFLKKHGGSD NASTDCERTV FQFDVQRKYF KEALDRWAQF
310 320 330 340 350
FIHPLMIRDA IDREVEAVDS EYQLARPSDA NRKEMLFGSL ARPGHPMKKF
360 370 380 390 400
FWGNADTLKH ESKKNNIDTY TRLRDFWQRH YSAHYMTLVV QSKETLDTLE
410 420 430 440 450
KWVTEIFSEI PNNGLPKPSF GHLTQPFDTP EFHKLYRVVP IRKVHSLSIT
460 470 480 490 500
WALPPQEEYY RVKPLHYISW LVGHEGKGSV LSFLRKKFWA LALYGGNGET
510 520 530 540 550
GFEQNSTYSI FSISVTLTDE GYKHFYEVAH VVFQYVKMLQ QRGPDKRIWE
560 570 580 590 600
EIQKIEANEF HYQEQTDPVD YVESLCENMQ LFPKEDFLTG DQLLFEYKPE
610 620 630 640 650
IIADALNQLS PQRANLVLLS AANEGQCHLK ERWFGTQYSV EDIDKYWSDL
660 670 680 690 700
WASDFELNQD LHLPEENKYI ATDFALKVAD CPETEYPVKA LSTQQGCLWC
710 720 730 740 750
RKDDKFKIPK GYIRFHLISP LIQRSAENIV LFDTFVNILS HNLGEPAYEA
760 770 780 790 800
DVAQLEYKLV AGEHGLIIRV KGFNHKLPLL FQLIIDYLTD FSFTPAVFEM
810 820 830 840 850
ITEQLKKTYF NILIKPETLA KDVRLLILEH SRWSMIDKYQ TLMKGLSIEA
860 870 880 890 900
LSSFVKAFKS QLFVEGLVQG NFTSREAKDF LNYVVQKLQF APLAHPCPVQ
910 920 930 940 950
FRVVDLPNTH LLCKVKTLNK GDANSEVTVY YQSGARSLRE YTLMELLVMH
960 970 980 990 1000
MEEPCFDFLR TKQTLGYHVY PTCRNTSGIL GFSVTVATQA TKYNSELVDK
1010 1020 1030 1040 1050
KIEEFLSCFE EKIKHLTEEA FSTQVTALIK LKECEDSHLG EEVDRNWNEV
1060 1070 1080 1090 1100
VTQQYLFDRL AREIEALKSV TKSDLVSWFH AHRSSKEKVL SVHVVGFGKH
1110 1120 1130 1140 1150
EGDAEVTALS EAQNSSSGEI PHLNFLPPST LMADVTSIKD IKAYTSTLNV

LPYHKILK
Length:1,158
Mass (Da):132,231
Last modified:November 23, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iF8731EA06460D028
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AJ719396 mRNA Translation: CAG31055.1

NCBI Reference Sequences

More...
RefSeqi
NP_001026455.1, NM_001031284.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
424635

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
gga:424635

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ719396 mRNA Translation: CAG31055.1
RefSeqiNP_001026455.1, NM_001031284.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

MEROPSiM16.005

Genome annotation databases

GeneIDi424635
KEGGigga:424635

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
4898

Phylogenomic databases

eggNOGiKOG0959 Eukaryota
COG1025 LUCA
KOiK01411
OrthoDBi1008844at2759
PhylomeDBiQ5ZMI8

Family and domain databases

InterProiView protein in InterPro
IPR011249 Metalloenz_LuxS/M16
IPR011765 Pept_M16_N
IPR001431 Pept_M16_Zn_BS
IPR007863 Peptidase_M16_C
IPR032632 Peptidase_M16_M
PfamiView protein in Pfam
PF00675 Peptidase_M16, 1 hit
PF05193 Peptidase_M16_C, 2 hits
PF16187 Peptidase_M16_M, 1 hit
SUPFAMiSSF63411 SSF63411, 4 hits
PROSITEiView protein in PROSITE
PS00143 INSULINASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5ZMI8_CHICK
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5ZMI8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: February 26, 2020
This is version 87 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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