UniProtKB - Q5ZLG3 (DIEXF_CHICK)
Protein
Digestive organ expansion factor homolog
Gene
DIEXF
Organism
Gallus gallus (Chicken)
Status
Functioni
Regulates the p53 pathway to control the expansion growth of digestive organs.By similarity
GO - Molecular functioni
- rRNA binding Source: GO_Central
- U3 snoRNA binding Source: GO_Central
GO - Biological processi
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: GO_Central
- multicellular organism development Source: UniProtKB-KW
- positive regulation of embryonic development Source: UniProtKB
- protein catabolic process Source: UniProtKB
- protein destabilization Source: UniProtKB
Keywordsi
Molecular function | Developmental protein |
Names & Taxonomyi
Protein namesi | Recommended name: Digestive organ expansion factor homolog |
Gene namesi | Name:DIEXF Synonyms:DEF ORF Names:RCJMB04_6f17 |
Organismi | Gallus gallus (Chicken) |
Taxonomic identifieri | 9031 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus |
Proteomesi |
|
Subcellular locationi
Nucleus
- Nucleus By similarity
Nucleus
- nucleolus Source: UniProtKB
Other locations
- small-subunit processome Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000254152 | 1 – 772 | Digestive organ expansion factor homologAdd BLAST | 772 |
Proteomic databases
PaxDbi | Q5ZLG3 |
Family & Domainsi
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 82 – 219 | Glu-richAdd BLAST | 138 |
Sequence similaritiesi
Belongs to the def family.Curated
Phylogenomic databases
eggNOGi | KOG2340, Eukaryota |
InParanoidi | Q5ZLG3 |
OrthoDBi | 257318at2759 |
PhylomeDBi | Q5ZLG3 |
Family and domain databases
InterProi | View protein in InterPro IPR010678, Digest_organ_expansion_fac-prd IPR027417, P-loop_NTPase |
PANTHERi | PTHR12933, PTHR12933, 1 hit |
Pfami | View protein in Pfam PF06862, UTP25, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5ZLG3-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MGKRRGGREL ARGLSKRQRK HLRQFGEQHP VCDRVSGRPE ATQICELSDN
60 70 80 90 100
SDKSSAESDS ETEVEQVSVY HKLLATLKAS PESESEEEED ESESEEAGES
110 120 130 140 150
EAELDSEGSQ EPKEAVGGEE EQNDVPEQEE EVAAKDPPEQ AFGQEEADGV
160 170 180 190 200
ETSCDPNRGA IEEFTDVKHE AEFSLETNFM EEESGDCDAD KRESNSSQAF
210 220 230 240 250
SEDPFKQHMD KELEEKEVEK ISTLSKTSSQ SKWPRLGQLT FSSTLEKHTT
260 270 280 290 300
LKPDKEFSVK QLYLHKPLES TWPKVNKHYL SSASKPSDSF FTPLQRELFC
310 320 330 340 350
IMNTYRDLFY PERNALTNGE EIRHAYCLHA LNHILKANAQ VLSNNAKKRD
360 370 380 390 400
QKPGTDSDDY RDQGLTRPKV LMIVPFRECA LRIVHIFISL LEVNEKRKID
410 420 430 440 450
VSNKKRFKGE FGSDPDEKPP NLKRPEDYEA VFAGNIDDHF RIGVAILQKS
460 470 480 490 500
MRLYAPFYSS DIIIASPLGM RTIIGTEGEK KRDFDFLSSI EMLIIDQADI
510 520 530 540 550
YLMQNWEHVL HLMRHINLLP LDSHGVDFSR VRMPNLNNWS KYYRQTLLFS
560 570 580 590 600
ALQDPQINAI FNKHCFNYVG QVAVRNVPLS GSISRVVVQL PHVFRRIEAE
610 620 630 640 650
NLTSVIDTRF QFFIDKVLPE YRDAIMSHTL IYVPSYFDYV RLRNYFKKEE
660 670 680 690 700
LNFTHICEYT KKAGICRARR SFLKGEKQFL LLTERFHFYK RYTIKGIRNL
710 720 730 740 750
IFYELPTYSH FYSEICNMMK ATDSGVDATW TCTVLYSKYD AQKLAAVVGI
760 770
DRTAQMLQSK KNVHLFVTGE NE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ719771 mRNA Translation: CAG31430.1 |
RefSeqi | NP_001026222.1, NM_001031051.1 |
Genome annotation databases
GeneIDi | 421384 |
KEGGi | gga:421384 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ719771 mRNA Translation: CAG31430.1 |
RefSeqi | NP_001026222.1, NM_001031051.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9031.ENSGALP00000016054 |
Proteomic databases
PaxDbi | Q5ZLG3 |
Genome annotation databases
GeneIDi | 421384 |
KEGGi | gga:421384 |
Organism-specific databases
CTDi | 421384 |
Phylogenomic databases
eggNOGi | KOG2340, Eukaryota |
InParanoidi | Q5ZLG3 |
OrthoDBi | 257318at2759 |
PhylomeDBi | Q5ZLG3 |
Miscellaneous databases
PROi | PR:Q5ZLG3 |
Family and domain databases
InterProi | View protein in InterPro IPR010678, Digest_organ_expansion_fac-prd IPR027417, P-loop_NTPase |
PANTHERi | PTHR12933, PTHR12933, 1 hit |
Pfami | View protein in Pfam PF06862, UTP25, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | DIEXF_CHICK | |
Accessioni | Q5ZLG3Primary (citable) accession number: Q5ZLG3 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | October 31, 2006 |
Last sequence update: | November 23, 2004 | |
Last modified: | December 2, 2020 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families