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Protein

Solute carrier family 25 member 36

Gene

SLC25A36

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Mitochondrial transporter that imports/exports pyrimidine nucleotides into and from mitochondria. Transports preferentially cytosine and uracil (deoxy)nucleoside mono-, di-, and triphosphates by uniport and antiport mechanism.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport

Names & Taxonomyi

Protein namesi
Recommended name:
Solute carrier family 25 member 36
Gene namesi
Name:SLC25A36
ORF Names:RCJMB04_9m7
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 9

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei7 – 27Helical; Name=1Sequence analysisAdd BLAST21
Transmembranei41 – 57Helical; Name=2Sequence analysisAdd BLAST17
Transmembranei113 – 133Helical; Name=3Sequence analysisAdd BLAST21
Transmembranei182 – 202Helical; Name=4Sequence analysisAdd BLAST21
Transmembranei228 – 248Helical; Name=5Sequence analysisAdd BLAST21
Transmembranei293 – 313Helical; Name=6Sequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002917991 – 313Solute carrier family 25 member 36Add BLAST313

Proteomic databases

PaxDbiQ5ZKP7

Expressioni

Gene expression databases

BgeeiENSGALG00000005283

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000008458

Structurei

3D structure databases

ProteinModelPortaliQ5ZKP7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati4 – 110Solcar 1Add BLAST107
Repeati118 – 205Solcar 2Add BLAST88
Repeati226 – 310Solcar 3Add BLAST85

Sequence similaritiesi

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0757 Eukaryota
ENOG410XS20 LUCA
GeneTreeiENSGT00550000074670
HOGENOMiHOG000188210
HOVERGENiHBG059891
InParanoidiQ5ZKP7
KOiK15116
OMAiESTLQWV
OrthoDBiEOG091G0BCW
PhylomeDBiQ5ZKP7
TreeFamiTF314220

Family and domain databases

Gene3Di1.50.40.10, 1 hit
InterProiView protein in InterPro
IPR002067 Mit_carrier
IPR018108 Mitochondrial_sb/sol_carrier
IPR023395 Mt_carrier_dom_sf
PfamiView protein in Pfam
PF00153 Mito_carr, 3 hits
PRINTSiPR00926 MITOCARRIER
SUPFAMiSSF103506 SSF103506, 1 hit
PROSITEiView protein in PROSITE
PS50920 SOLCAR, 3 hits

Sequencei

Sequence statusi: Complete.

Q5ZKP7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSQRDTLVHL FAGGCGGTVG AILTCPLEVV KTRLQSSSVT LYISEVHLNT
60 70 80 90 100
VNGASVNRVT RVSPGPLHCL KMILQKEGPR SLFRGLGPNL VGVAPSRAIY
110 120 130 140 150
FAAYSNCKEK LNNIFNPDST QVHMISAGVA GFTAITMTNP IWLVKTRLQL
160 170 180 190 200
DARNRGEKRM SAFECVRKVY RSDGIKGFYR GMSASYAGIS ETVIHFVIYE
210 220 230 240 250
SIKRKLLEHK TASAMDSEDE SAKEASDFVG MMMAAATSKT CATSIAYPHE
260 270 280 290 300
VVRTRLREEG TKYRSFFQTL SLLVREEGYG SLYRGLTTHL VRQIPNTAIM
310
MSTYEVVVYL LDG
Length:313
Mass (Da):34,557
Last modified:November 23, 2004 - v1
Checksum:iBA653E2132E4B006
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720037 mRNA Translation: CAG31696.1
RefSeqiNP_001007961.1, NM_001007960.1
UniGeneiGga.15825

Genome annotation databases

EnsembliENSGALT00000008472; ENSGALP00000008458; ENSGALG00000005283
GeneIDi424817
KEGGigga:424817

Similar proteinsi

Entry informationi

Entry nameiS2536_CHICK
AccessioniPrimary (citable) accession number: Q5ZKP7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: November 23, 2004
Last modified: March 28, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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