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UniProtKB - Q5ZKJ0 (CLP1L_CHICK)
Protein
Cleft lip and palate transmembrane protein 1-like protein
Gene
CLPTM1L
Organism
Gallus gallus (Chicken)
Status
Functioni
May enhance cisplatin-mediated apoptosis, when overexpressed.
By similarityGO - Biological processi
- apoptotic process Source: UniProtKB-KW
Keywordsi
Biological process | Apoptosis |
Names & Taxonomyi
Protein namesi | Recommended name: Cleft lip and palate transmembrane protein 1-like proteinShort name: CLPTM1-like protein |
Gene namesi | Name:CLPTM1L ORF Names:RCJMB04_10g15 |
Organismi | Gallus gallus (Chicken) |
Taxonomic identifieri | 9031 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archelosauria › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galloanserae › Galliformes › Phasianidae › Phasianinae › Gallus |
Proteomesi |
|
Subcellular locationi
Other locations
- Membrane Curated; Multi-pass membrane protein Curated
Other locations
- integral component of membrane Source: UniProtKB-KW
- membrane Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Topological domaini | 1 – 9 | CytoplasmicSequence analysis | 9 | |
Transmembranei | 10 – 30 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 31 – 284 | ExtracellularSequence analysisAdd BLAST | 254 | |
Transmembranei | 285 – 305 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 306 – 324 | CytoplasmicSequence analysisAdd BLAST | 19 | |
Transmembranei | 325 – 342 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 343 – 346 | ExtracellularSequence analysis | 4 | |
Transmembranei | 347 – 364 | HelicalSequence analysisAdd BLAST | 18 | |
Topological domaini | 365 – 402 | CytoplasmicSequence analysisAdd BLAST | 38 | |
Transmembranei | 403 – 423 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 424 – 428 | ExtracellularSequence analysis | 5 | |
Transmembranei | 429 – 449 | HelicalSequence analysisAdd BLAST | 21 | |
Topological domaini | 450 – 536 | CytoplasmicSequence analysisAdd BLAST | 87 |
Keywords - Cellular componenti
MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000331303 | 1 – 536 | Cleft lip and palate transmembrane protein 1-like proteinAdd BLAST | 536 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Glycosylationi | 92 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 102 | N-linked (GlcNAc...) asparagineSequence analysis | 1 | |
Glycosylationi | 229 | N-linked (GlcNAc...) asparagineSequence analysis | 1 |
Keywords - PTMi
GlycoproteinProteomic databases
PaxDbi | Q5ZKJ0 |
Structurei
Family & Domainsi
Sequence similaritiesi
Belongs to the CLPTM1 family.Curated
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | KOG2489, Eukaryota |
InParanoidi | Q5ZKJ0 |
PhylomeDBi | Q5ZKJ0 |
Family and domain databases
InterProi | View protein in InterPro IPR008429, CLPTM1 IPR030434, CLPTM1L |
PANTHERi | PTHR21347, PTHR21347, 1 hit PTHR21347:SF12, PTHR21347:SF12, 1 hit |
Pfami | View protein in Pfam PF05602, CLPTM1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5ZKJ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLSRSSFTSL AVGVFAVYVA HTCWVMYGIV YTRPCPSGGA AACVWPYLAR
60 70 80 90 100
RPKLQLSVYT TTRSNIGAES NIDLVLNVED FDIESKFERT VNVSVPKKTR
110 120 130 140 150
NNGTLYAYIF LHHAGVLPWH DGKQVHIVSP LTTYMVPKPE EINLLTGEST
160 170 180 190 200
TQQIEAEKQT SALDEPVSHW RSRLTLNVMV EDFVFDGSSL PADVHRYMKM
210 220 230 240 250
VQLGKTVHYL PILFIDQLSN RVKDLMVINR STTELPLTVS YDKISLGKLR
260 270 280 290 300
FWIHMQDAVY SLQQFGFSEK DADEVKGIFV DTNLYFLALT FFVAAFHLLF
310 320 330 340 350
DFLAFKNDIS FWKKKRSMIG MSTKAVLWRC FSTVVIFLFL LDEQTSLLVL
360 370 380 390 400
IPAGIGAVIE LWKVKKALKM TVKWQGIRPK VQFGASNDSE KKTEEYDTQA
410 420 430 440 450
MKYLSYLLYP LCIGGAAYSL LNVKYKSWYS WLINSFVNGV YAFGFLFMLP
460 470 480 490 500
QLFVNYKMKS VAHLPWKAFT YKAFNTFIDD IFAFIITMPT SHRLACFRDD
510 520 530
VVFLVYLYQR WLYPVDKSRV NEYGESYEEK PKKKSS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ720094 mRNA Translation: CAG31753.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ720094 mRNA Translation: CAG31753.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9031.ENSGALP00000021513 |
Proteomic databases
PaxDbi | Q5ZKJ0 |
Phylogenomic databases
eggNOGi | KOG2489, Eukaryota |
InParanoidi | Q5ZKJ0 |
PhylomeDBi | Q5ZKJ0 |
Family and domain databases
InterProi | View protein in InterPro IPR008429, CLPTM1 IPR030434, CLPTM1L |
PANTHERi | PTHR21347, PTHR21347, 1 hit PTHR21347:SF12, PTHR21347:SF12, 1 hit |
Pfami | View protein in Pfam PF05602, CLPTM1, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | CLP1L_CHICK | |
Accessioni | Q5ZKJ0Primary (citable) accession number: Q5ZKJ0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | April 29, 2008 |
Last sequence update: | November 23, 2004 | |
Last modified: | February 23, 2022 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families