Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Vesicle-trafficking protein SEC22b

Gene

SEC22B

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-GGA-1236974 ER-Phagosome pathway
R-GGA-204005 COPII-mediated vesicle transport
R-GGA-5694530 Cargo concentration in the ER
R-GGA-6811434 COPI-dependent Golgi-to-ER retrograde traffic

Names & Taxonomyi

Protein namesi
Recommended name:
Vesicle-trafficking protein SEC22b
Alternative name(s):
SEC22 vesicle-trafficking protein homolog B
Gene namesi
Name:SEC22BBy similarity
ORF Names:RCJMB04_15c3
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 8

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 194CytoplasmicSequence analysisAdd BLAST194
Transmembranei195 – 215HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002522421 – 215Vesicle-trafficking protein SEC22bAdd BLAST215

Proteomic databases

PaxDbiQ5ZJW4
PRIDEiQ5ZJW4

Expressioni

Gene expression databases

BgeeiENSGALG00000026268 Expressed in 11 organ(s), highest expression level in liver

Interactioni

Subunit structurei

Component of 2 distinct SNARE complexes.By similarity

GO - Molecular functioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000004591

Structurei

3D structure databases

ProteinModelPortaliQ5ZJW4
SMRiQ5ZJW4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 119LonginPROSITE-ProRule annotationAdd BLAST114
Domaini134 – 194v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd BLAST61

Sequence similaritiesi

Belongs to the synaptobrevin family.Sequence analysis

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG0862 Eukaryota
COG5143 LUCA
GeneTreeiENSGT00510000046833
HOGENOMiHOG000044957
HOVERGENiHBG052748
InParanoidiQ5ZJW4
KOiK08517
OMAiMLCASVD
OrthoDBiEOG091G0MPE
PhylomeDBiQ5ZJW4

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR010908 Longin_dom
IPR001388 Synaptobrevin
PfamiView protein in Pfam
PF13774 Longin, 1 hit
PF00957 Synaptobrevin, 1 hit
PRINTSiPR00219 SYNAPTOBREVN
SMARTiView protein in SMART
SM01270 Longin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS50859 LONGIN, 1 hit
PS50892 V_SNARE, 1 hit

Sequencei

Sequence statusi: Complete.

Q5ZJW4-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVLLTMIARV ADGLPLAASM QEDEQSGRDL QQYQSQAKQL FRKLNEQSPT
60 70 80 90 100
RCTLEAGAMA FHYIIEKGVC YLVLCEAAFP KKLAFAYLED LQSEFDEQHG
110 120 130 140 150
KKVPTVSRPY SFIEFDTYIQ KTKKLYIDSR ARRNLGSINT ELQDVQRIMV
160 170 180 190 200
ANIEEVLQRG EALSALDSKA NNLSSLSKKY RQDAKYLNMR STYAKLAAVA
210
VFFIMLIVYV RFWWL
Length:215
Mass (Da):24,718
Last modified:November 23, 2004 - v1
Checksum:iB0ADF3A7CF16C870
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720320 mRNA Translation: CAG31979.1
RefSeqiNP_001026437.1, NM_001031266.3
UniGeneiGga.1782

Genome annotation databases

EnsembliENSGALT00000079169; ENSGALP00000051201; ENSGALG00000039704
GeneIDi424377
KEGGigga:424377

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720320 mRNA Translation: CAG31979.1
RefSeqiNP_001026437.1, NM_001031266.3
UniGeneiGga.1782

3D structure databases

ProteinModelPortaliQ5ZJW4
SMRiQ5ZJW4
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9031.ENSGALP00000004591

Proteomic databases

PaxDbiQ5ZJW4
PRIDEiQ5ZJW4

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSGALT00000079169; ENSGALP00000051201; ENSGALG00000039704
GeneIDi424377
KEGGigga:424377

Organism-specific databases

CTDi9554

Phylogenomic databases

eggNOGiKOG0862 Eukaryota
COG5143 LUCA
GeneTreeiENSGT00510000046833
HOGENOMiHOG000044957
HOVERGENiHBG052748
InParanoidiQ5ZJW4
KOiK08517
OMAiMLCASVD
OrthoDBiEOG091G0MPE
PhylomeDBiQ5ZJW4

Enzyme and pathway databases

ReactomeiR-GGA-1236974 ER-Phagosome pathway
R-GGA-204005 COPII-mediated vesicle transport
R-GGA-5694530 Cargo concentration in the ER
R-GGA-6811434 COPI-dependent Golgi-to-ER retrograde traffic

Miscellaneous databases

PROiPR:Q5ZJW4

Gene expression databases

BgeeiENSGALG00000026268 Expressed in 11 organ(s), highest expression level in liver

Family and domain databases

InterProiView protein in InterPro
IPR011012 Longin-like_dom_sf
IPR010908 Longin_dom
IPR001388 Synaptobrevin
PfamiView protein in Pfam
PF13774 Longin, 1 hit
PF00957 Synaptobrevin, 1 hit
PRINTSiPR00219 SYNAPTOBREVN
SMARTiView protein in SMART
SM01270 Longin, 1 hit
SUPFAMiSSF64356 SSF64356, 1 hit
PROSITEiView protein in PROSITE
PS50859 LONGIN, 1 hit
PS50892 V_SNARE, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSC22B_CHICK
AccessioniPrimary (citable) accession number: Q5ZJW4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: November 23, 2004
Last modified: September 12, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again