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Protein

Density-regulated protein

Gene

DENR

Organism
Gallus gallus (Chicken)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

May be involved in the translation of target mRNAs by scanning and recognition of the initiation codon. Involved in translation initiation; promotes recruitment of aminoacetyled initiator tRNA to P site of 40S ribosomes. Can promote release of deacylated tRNA and mRNA from recycled 40S subunits following ABCE1-mediated dissociation of post-termination ribosomal complexes into subunits (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionInitiation factor
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Density-regulated protein
Short name:
DRP
Gene namesi
Name:DENR
ORF Names:RCJMB04_20p1
OrganismiGallus gallus (Chicken)
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus
Proteomesi
  • UP000000539 Componenti: Chromosome 15

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001306031 – 198Density-regulated proteinAdd BLAST198

Proteomic databases

PaxDbiQ5ZJ39
PRIDEiQ5ZJ39

Expressioni

Gene expression databases

BgeeiENSGALG00000003795
ExpressionAtlasiQ5ZJ39 baseline and differential

Interactioni

Protein-protein interaction databases

STRINGi9031.ENSGALP00000006010

Structurei

3D structure databases

ProteinModelPortaliQ5ZJ39
SMRiQ5ZJ39
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini115 – 182SUI1PROSITE-ProRule annotationAdd BLAST68

Sequence similaritiesi

Belongs to the DENR family.Curated

Phylogenomic databases

eggNOGiKOG3239 Eukaryota
COG0023 LUCA
GeneTreeiENSGT00390000014349
HOGENOMiHOG000237611
HOVERGENiHBG005471
InParanoidiQ5ZJ39
OrthoDBiEOG091G0R9X
PhylomeDBiQ5ZJ39

Family and domain databases

InterProiView protein in InterPro
IPR005873 Drp1
IPR001950 SUI1
IPR005872 SUI1_arc_bac
IPR036877 SUI1_dom_sf
PANTHERiPTHR12789 PTHR12789, 1 hit
PfamiView protein in Pfam
PF01253 SUI1, 1 hit
SUPFAMiSSF55159 SSF55159, 2 hits
TIGRFAMsiTIGR01159 DRP1, 1 hit
PROSITEiView protein in PROSITE
PS50296 SUI1, 1 hit

Sequencei

Sequence statusi: Complete.

Q5ZJ39-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATDVAEPVV PDCRGDIRSG ARSDADYPLR VLYCGVCSLP TEYCEYMPDV
60 70 80 90 100
TKCRQWLEKN FPDEFAKLTV ENSPKQEAGV GEGQGTAGEE EEKKKQKRGG
110 120 130 140 150
RGQIKQKKKT VPQKVTIAKI PRAKKKYVTR VCGLATFEID LKEAQRFFAQ
160 170 180 190
KFSCGASVTG EDEIIIQGDF TDDIIDVIQE KWPEVDDDSI EDLGEVKK
Length:198
Mass (Da):22,158
Last modified:November 23, 2004 - v1
Checksum:i2A43A2FF5D6EC9C4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ720595 mRNA Translation: CAG32254.1
RefSeqiNP_001072973.1, NM_001079505.1
UniGeneiGga.8483

Genome annotation databases

EnsembliENSGALT00000034620; ENSGALP00000033977; ENSGALG00000003795
GeneIDi771794
KEGGigga:771794

Similar proteinsi

Entry informationi

Entry nameiDENR_CHICK
AccessioniPrimary (citable) accession number: Q5ZJ39
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 24, 2006
Last sequence update: November 23, 2004
Last modified: May 23, 2018
This is version 65 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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