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Entry version 127 (07 Oct 2020)
Sequence version 1 (23 Nov 2004)
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Protein
Submitted name:

Anchor protein

Gene

RESDA1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:3 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Receptor that may have an important role in cell/cell signaling during nervous system formation.ARBA annotation

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionDevelopmental proteinARBA annotation, G-protein coupled receptorARBA annotation, Receptor, Transducer
LigandCalciumARBA annotation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Anchor proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:RESDA1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei2608 – 2632HelicalSequence analysisAdd BLAST25
Transmembranei2644 – 2663HelicalSequence analysisAdd BLAST20
Transmembranei2697 – 2719HelicalSequence analysisAdd BLAST23
Transmembranei2740 – 2760HelicalSequence analysisAdd BLAST21
Transmembranei2780 – 2801HelicalSequence analysisAdd BLAST22
Transmembranei2822 – 2843HelicalSequence analysisAdd BLAST22
Transmembranei3503 – 3530HelicalSequence analysisAdd BLAST28
Transmembranei3592 – 3615HelicalSequence analysisAdd BLAST24
Transmembranei3669 – 3688HelicalSequence analysisAdd BLAST20
Transmembranei3700 – 3718HelicalSequence analysisAdd BLAST19
Transmembranei3749 – 3773HelicalSequence analysisAdd BLAST25
Transmembranei3785 – 3804HelicalSequence analysisAdd BLAST20
Transmembranei3816 – 3836HelicalSequence analysisAdd BLAST21
Transmembranei3848 – 3865HelicalSequence analysisAdd BLAST18
Transmembranei3880 – 3911HelicalSequence analysisAdd BLAST32

Keywords - Cellular componenti

Cell membraneARBA annotation, Membrane

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi1493 ↔ 1502PROSITE-ProRule annotation
Disulfide bondi1531 ↔ 1540PROSITE-ProRule annotation
Disulfide bondi1818 ↔ 1827PROSITE-ProRule annotation
Disulfide bondi2080 ↔ 2089PROSITE-ProRule annotation
Disulfide bondi2147 ↔ 2159PROSITE-ProRule annotation
Disulfide bondi2149 ↔ 2166PROSITE-ProRule annotation
Disulfide bondi2168 ↔ 2177PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationARBA annotation, GlycoproteinARBA annotation, HydroxylationARBA annotation, PhosphoproteinARBA annotation

Proteomic databases

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5Y190

PeptideAtlas

More...
PeptideAtlasi
Q5Y190

Consortium for Top Down Proteomics

More...
TopDownProteomicsi
Q5Y190

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1445 – 1503EGF-likeInterPro annotationAdd BLAST59
Domaini1505 – 1541EGF-likeInterPro annotationAdd BLAST37
Domaini1545 – 1584EGF-likeInterPro annotationAdd BLAST40
Domaini1585 – 1789LAM_G_DOMAINInterPro annotationAdd BLAST205
Domaini1792 – 1828EGF-likeInterPro annotationAdd BLAST37
Domaini1834 – 2014LAM_G_DOMAINInterPro annotationAdd BLAST181
Domaini2016 – 2049EGF-likeInterPro annotationAdd BLAST34
Domaini2052 – 2090EGF-likeInterPro annotationAdd BLAST39
Domaini2147 – 2194Laminin EGF-likeInterPro annotationAdd BLAST48
Domaini2179 – 2252G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST74
Domaini2547 – 2599GPSInterPro annotationAdd BLAST53
Domaini2609 – 2873G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST265
Domaini3935 – 4128STASInterPro annotationAdd BLAST194

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni46 – 123DisorderedSequence analysisAdd BLAST78
Regioni160 – 269DisorderedSequence analysisAdd BLAST110
Regioni282 – 380DisorderedSequence analysisAdd BLAST99
Regioni2431 – 2469DisorderedSequence analysisAdd BLAST39
Regioni2986 – 3025DisorderedSequence analysisAdd BLAST40
Regioni3076 – 3104DisorderedSequence analysisAdd BLAST29
Regioni3184 – 3315DisorderedSequence analysisAdd BLAST132
Regioni3358 – 3405DisorderedSequence analysisAdd BLAST48
Regioni4018 – 4044DisorderedSequence analysisAdd BLAST27

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili3979 – 4005Sequence analysisAdd BLAST27

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi46 – 78PolarSequence analysisAdd BLAST33
Compositional biasi215 – 242PolarSequence analysisAdd BLAST28
Compositional biasi2436 – 2461PolarSequence analysisAdd BLAST26
Compositional biasi3077 – 3098PolarSequence analysisAdd BLAST22
Compositional biasi3207 – 3221PolyampholyteSequence analysisAdd BLAST15
Compositional biasi3260 – 3275Pro-richSequence analysisAdd BLAST16
Compositional biasi3289 – 3304PolarSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily.ARBA annotation
Belongs to the SLC26A/SulP transporter (TC 2.A.53) family. [View classification]ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, EGF-like domainPROSITE-ProRule annotationARBA annotation, Laminin EGF-like domainPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, SignalARBA annotation, Transmembrane, Transmembrane helixSequence analysisARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
4.10.1240.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR032471, GAIN_dom_N
IPR017981, GPCR_2-like
IPR036445, GPCR_2_extracell_dom_sf
IPR001879, GPCR_2_extracellular_dom
IPR000832, GPCR_2_secretin-like
IPR017983, GPCR_2_secretin-like_CS
IPR000203, GPS
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR018045, S04_transporter_CS
IPR011547, SLC26A/SulP_dom
IPR001902, SLC26A/SulP_fam
IPR002645, STAS_dom
IPR036513, STAS_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00002, 7tm_2, 1 hit
PF00028, Cadherin, 8 hits
PF00008, EGF, 2 hits
PF16489, GAIN, 1 hit
PF00053, Laminin_EGF, 1 hit
PF02210, Laminin_G_2, 2 hits
PF01740, STAS, 1 hit
PF00916, Sulfate_transp, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00205, CADHERIN
PR00249, GPCRSECRETIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00112, CA, 9 hits
SM00181, EGF, 6 hits
SM00179, EGF_CA, 5 hits
SM00180, EGF_Lam, 1 hit
SM00303, GPS, 1 hit
SM00008, HormR, 1 hit
SM00282, LamG, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF49313, SSF49313, 9 hits
SSF49899, SSF49899, 2 hits
SSF52091, SSF52091, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00815, sulP, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00232, CADHERIN_1, 6 hits
PS00022, EGF_1, 4 hits
PS01186, EGF_2, 3 hits
PS50026, EGF_3, 6 hits
PS01248, EGF_LAM_1, 1 hit
PS50027, EGF_LAM_2, 1 hit
PS00650, G_PROTEIN_RECEP_F2_2, 1 hit
PS50227, G_PROTEIN_RECEP_F2_3, 1 hit
PS50261, G_PROTEIN_RECEP_F2_4, 1 hit
PS50221, GPS, 1 hit
PS50025, LAM_G_DOMAIN, 2 hits
PS01130, SLC26A, 1 hit
PS50801, STAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5Y190-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGPPSKRLSE VEAATFHRKP MGGKYGVLVG DALLTAYCQK ARISHSTPSQ
60 70 80 90 100
SYENAHGHQN FRPKSGTRFR TSGQEGGTRD LEGQKKAGRR SWDSALEGGS
110 120 130 140 150
QEELGGGGHQ GWDPGLAATT GPRAHIGGGA LALCPESSGV REDGGPGLGV
160 170 180 190 200
REPIFVGLRG RRQSARNSRG PPEQPNEELG IEHGVQPLGS RERETGQGPG
210 220 230 240 250
SVLYWRPEVS SCGRTGPLQR GSLSPGALSS GVPGSGNSSP LPSDFLIRHH
260 270 280 290 300
GPKPVSSQRN AGTGSRKRVG TARCCGELWA TGSKGQGERA TTSGAERTAP
310 320 330 340 350
RRNCLPGASG SGPELDSAPR TARTAPASGS APRESRTAPE PAPKRMRSRG
360 370 380 390 400
LFRCRFLPQR PGPRPPGLPA RPEARKVTSA NRARFRRAAN RHPQFPQYNY
410 420 430 440 450
QTLVPENEAA GTAVLRVVAQ DPDAGEAGRL VYSLAALMNS RSLELFSIDP
460 470 480 490 500
QSGLIRTAAA LDRESMERHY LRVTAQDHGS PRLSATTMVA VTVADRNDHS
510 520 530 540 550
PVFEQAQYRE TLRENVEEGY PILQLRATDG DAPPNANLRY RFVGPPAARA
560 570 580 590 600
AAAAAFEIDP RSGLISTSGR VDREHMESYE LVVEASDQGQ EPGPRSATVR
610 620 630 640 650
VHITVLDEND NAPQFSEKRY VAQVREDVRP HTVVLRVTAT DRDKDANGLV
660 670 680 690 700
HYNIISGNSR GHFAIDSLTG EIQVVAPLDF EAEREYALRI RAQDAGRPPL
710 720 730 740 750
SNNTGLASIQ VVDINDHIPI FVSTPFQVSV LENAPLGHSV IHIQAVDADH
760 770 780 790 800
GENARLEYSL TGVAPDTPFV INSATGWVSV SGPLDRESVE HYFFGVEARD
810 820 830 840 850
HGSPPLSASA SVTVTVLDVN DNRPEFTMKE YHLRLNEDAA VGTSVVSVTA
860 870 880 890 900
VDRDANSAIS YQITGGNTRN RFAISTQGGV GLVTLALPLD YKQERYFKLV
910 920 930 940 950
LTASDRALHD HCYVHINITD ANTHRPVFQS AHYSVSVNED RPMGSTIVVI
960 970 980 990 1000
SASDDDVGEN ARITYLLEDN LPQFRIDADS GAITLQAPLD YEDQVTYTLA
1010 1020 1030 1040 1050
ITARDNGIPQ KADTTYVEVM VNDVNDNAPQ FVASHYTGLV SEDAPPFTSV
1060 1070 1080 1090 1100
LQISATDRDA HANGRVQYTF QNGEDGDGDF TIEPTSGIVR TVRRLDREAV
1110 1120 1130 1140 1150
SVYELTAYAV DRGVPPLRTP VSIQVMVQDV NDNAPVFPAE EFEVRVKENS
1160 1170 1180 1190 1200
IVGSVVAQIT AVDPDEGPNA HIMYQIVEGN IPELFQMDIF SGELTALIDL
1210 1220 1230 1240 1250
DYEARQEYVI VVQATSAPLV SRATVHVRLV DQNDNSPVLN NFQILFNNYV
1260 1270 1280 1290 1300
SNRSDTFPSG IIGRIPAYDP DVSDHLFYSF ERGNELQLLV VNQTSGELRL
1310 1320 1330 1340 1350
SRKLDNNRPL VASMLVTVTD GLHSVTAQCV LRVVIITEEL LANSLTVRLE
1360 1370 1380 1390 1400
NMWQERFLSP LLGRFLEGVA AVLATPAEDV FIFNIQNDTD VGGTVLNVSF
1410 1420 1430 1440 1450
SALAPRGAGA GAAGPWFSSE ELQEQLYVRR AALAARSLLD VLPFDDNVCL
1460 1470 1480 1490 1500
REPCENYMKC VSVLRFDSSA PFLASASTLF RPIQPIAGLR CRCPPGFTGD
1510 1520 1530 1540 1550
FCETELDLCY SNPCRNGGAC ARREGGYTCV CRPRFTGEDC ELDTEAGRCV
1560 1570 1580 1590 1600
PGVCRNGGTC TDAPNGGFRC QCPAGGAFEG PRCEVAARSF PPSSFVMFRG
1610 1620 1630 1640 1650
LRQRFHLTLS LSFATVQQSG LLFYNGRLNE KHDFLALELV AGQVRLTYST
1660 1670 1680 1690 1700
GESNTVVSPT VPGGLSDGQW HTVHLRYYNK PRTDALGGAQ GPSKDKVAVL
1710 1720 1730 1740 1750
SVDDCDVAVA LQFGAEIGNY SCAAAGVQTS SKKSLDLTGP LLLGGVPNLP
1760 1770 1780 1790 1800
ENFPVSHKDF IGCMRDLHID GRRVDMAAFV ANNGTMAGCQ AKLHFCDSGP
1810 1820 1830 1840 1850
CKNSGFCSER WGSFSCDCPV GFGGKDCQLT MAHPHHFRGN GTLSWNFGSD
1860 1870 1880 1890 1900
MAVSVPWYLG LAFRTRATQG VLMQVQAGPH STLLCQLDRG LLSVTVTRGS
1910 1920 1930 1940 1950
GRASHLLLDQ VTVSDGRWHD LRLELQEEPG GRRGHHVLMV SLDFSLFQDT
1960 1970 1980 1990 2000
MAVGSELQGL KVKQLHVGGL PPGSAEEAPQ GLVGCIQGVW LGSTPSGSPA
2010 2020 2030 2040 2050
LLPPSHRVNA EPGCVVTNAC ASGPCPPHAD CRDLWQTFSC TCQPGYYGPG
2060 2070 2080 2090 2100
CVDACLLNPC QNQGSCRHLP GAPHGYTCDC VGGYFGHHCE HRMDQQCPRG
2110 2120 2130 2140 2150
WWGSPTCGPC NCDVHKGFDP NCNKTNGQCH CKEFHYRPRG SDSCLPCDCY
2160 2170 2180 2190 2200
PVGSTSRSCA PHSGQCPCRP GALGRQCNSC DSPFAEVTAS GCRVLYDACP
2210 2220 2230 2240 2250
KSLRSGVWWP QTKFGVLATV PCPRGALGAA VRLCDEAQGW LEPDLFNCTS
2260 2270 2280 2290 2300
PAFRELSLLL DGLELNKTAL DTMEAKKLAQ RLREVTGHTD HYFSQDVRVT
2310 2320 2330 2340 2350
ARLLAHLLAF ESHQQGFGLT ATQDAHFNEN LLWAGSALLA PETGDLWAAL
2360 2370 2380 2390 2400
GQRAPGGSPG SAGLVRHLEE YAATLARNME LTYLNPMGLV TPNIMLSIDR
2410 2420 2430 2440 2450
MEHPSSPRGA RRYPRYHSNL FRGQDAWDPH THVLLPSQSP RPSPSEVLPT
2460 2470 2480 2490 2500
SSSIENSTTS SVVPPPAPPE PEPGISIIIL LVYRTLGGLL PAQFQAERRG
2510 2520 2530 2540 2550
ARLPQNPVMN SPVVSVAVFH GRNFLRGILE SPISLEFRLL QTANRSKAIC
2560 2570 2580 2590 2600
VQWDPPGLAE QHGVWTARDC ELVHRNGSHA RCRCSRTGTF GVLMDASPRE
2610 2620 2630 2640 2650
RLEGDLELLA VFTHVVVAVS VAALVLTAAI LLSLRSLKSN VRGIHANVAA
2660 2670 2680 2690 2700
ALGVAELLFL LGIHRTHNQV QDQGQGTCVL MTLLAQEAWG QNSGSELVCT
2710 2720 2730 2740 2750
AVAILLHYFF LSTFAWLFVQ GLHLYRMQVE PRNVDRGAMR FYHALGWGVP
2760 2770 2780 2790 2800
AVLLGLAVGL DPEGYGNPDF CWISVHEPLI WSFAGPVVLV IVMNGTMFLL
2810 2820 2830 2840 2850
AARTSCSTGQ REAKKTSALR TLRSSFLLLL LVSASWLFGL LAVNHSILAF
2860 2870 2880 2890 2900
HYLHAGLCGL QGLAVLLLFC VLNADARAAW MPACLGRKAA PEEARPAPGL
2910 2920 2930 2940 2950
GPGAYNNTAL FEESGLIRIT LGASTVSSVS SARSGRTQDQ DSQRGRSYLR
2960 2970 2980 2990 3000
DNVLVRHGSA ADHTDHSLQA HAGPTDLDVA MFHRDAGADS DSDSDLSLEE
3010 3020 3030 3040 3050
ERSLSIPSSE SEDNGRTRGR FQRPLCRAAQ SERLLTHPKD VDGNDLLSYW
3060 3070 3080 3090 3100
PALGECEAAP CALQTWGSER RLGLDTSKDA ANNNQPDPAL TSGDETSLGR
3110 3120 3130 3140 3150
AQRQRKGILK NRLQYPLVPQ TRGAPELSWC RAATLGHRAV PAASYGRIYA
3160 3170 3180 3190 3200
GGGTGSLSQP ASRYSSREQL DLLLRRQLSR ERLEEAPAPV LRPLSRPGSQ
3210 3220 3230 3240 3250
ECMDAAPGRL EPKDRGSTLP RRQPPRDYPG AMAGRFGSRD ALDLGAPREW
3260 3270 3280 3290 3300
LSTLPPPRRT RDLDPQPPPL PLSPQRQLSR DPLLPSRPLD SLSRSSNSRE
3310 3320 3330 3340 3350
QLDQVPSRHP SREALGPLPQ LLRAREDSVS GPSHGPSTEQ LDILSSILAS
3360 3370 3380 3390 3400
FNSSALSSVQ SSSTPLGPHT TATPSATASV LGPSTPRSAT SHSISELSPD
3410 3420 3430 3440 3450
SEPRDTQALL SATQAMDLRR RDYHMERPLL NQEHLEELGR WGSAPRTHQW
3460 3470 3480 3490 3500
RTWLQCSRAR AYALLLQHLP VLVWLPRYPV RDWLLGDLLS GLSVAIMQLP
3510 3520 3530 3540 3550
QGLAYALLAG LPPVFGLYSS FYPVFIYFLF GTSRHISVES LCVPGPVDTG
3560 3570 3580 3590 3600
TFAVMSVMVG SVTESLAPQA LNDSMINETA RDAARVQVAS TLSVLVGLFQ
3610 3620 3630 3640 3650
VGLGLIHFGF VVTYLSEPLV RGYTTAAAVQ VFVSQLKYVF GLHLSSHSGP
3660 3670 3680 3690 3700
LSLIYTVLEV CWKLPQSKVG TVVTAAVAGV VLVVVKLLND KLQQQLPMPI
3710 3720 3730 3740 3750
PGELLTLIGA TGISYGMGLK HRFEVDVVGN IPAGLVPPVA PNTQLFSKLV
3760 3770 3780 3790 3800
GSAFTIAVVG FAIAISLGKI FALRHGYRVD SNQELVALGL SNLIGGIFQC
3810 3820 3830 3840 3850
FPVSCSMSRS LVQESTGGNS QVAGAISSLF ILLIIVKLGE LFHDLPKAVL
3860 3870 3880 3890 3900
AAIIIVNLKG MLRQLSDMRS LWKANRADLL IWLVTFTATI LLNLDLGLVV
3910 3920 3930 3940 3950
AVIFSLLLVV VRTQMPHYSV LGQVPDTDIY RDVAEYSEAK EVRGVKVFRS
3960 3970 3980 3990 4000
SATVYFANAE FYSDALKQRC GVDVDFLISQ KKKLLKKQEQ LKLKQLQKEE
4010 4020 4030 4040 4050
KLRKQAGPLL SACLAPQQVS SGDKMEDATA NGQEDSKAPD GSTLKALGLP
4060 4070 4080 4090 4100
QPDFHSLILD LGALSFVDTV CLKSLKNIFH DFREIEVEVY MAACHSPVVS
4110 4120 4130 4140 4150
QLEAGHFFDA SITKKHLFAS VHDAVTFALQ HPRPVPDSPV SPSLAVSSDV
4160 4170 4180
KQLEPELLLR NNLLSGIPEK VQGSVGANGQ SLEDTE
Length:4,186
Mass (Da):453,240
Last modified:November 23, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iC7FA2B87474104DE
GO

Sequence databases

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EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
AY714129 mRNA Translation: AAU94938.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY714129 mRNA Translation: AAU94938.1

3D structure databases

Database of comparative protein structure models

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ModBasei
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SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

Information system for G protein-coupled receptors (GPCRs)

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GPCRDBi
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Proteomic databases

MaxQBiQ5Y190
PeptideAtlasiQ5Y190
TopDownProteomicsiQ5Y190

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
CELSR3, human

Family and domain databases

Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR002126, Cadherin-like_dom
IPR015919, Cadherin-like_sf
IPR020894, Cadherin_CS
IPR013320, ConA-like_dom_sf
IPR001881, EGF-like_Ca-bd_dom
IPR000742, EGF-like_dom
IPR032471, GAIN_dom_N
IPR017981, GPCR_2-like
IPR036445, GPCR_2_extracell_dom_sf
IPR001879, GPCR_2_extracellular_dom
IPR000832, GPCR_2_secretin-like
IPR017983, GPCR_2_secretin-like_CS
IPR000203, GPS
IPR002049, Laminin_EGF
IPR001791, Laminin_G
IPR018045, S04_transporter_CS
IPR011547, SLC26A/SulP_dom
IPR001902, SLC26A/SulP_fam
IPR002645, STAS_dom
IPR036513, STAS_dom_sf
PfamiView protein in Pfam
PF00002, 7tm_2, 1 hit
PF00028, Cadherin, 8 hits
PF00008, EGF, 2 hits
PF16489, GAIN, 1 hit
PF00053, Laminin_EGF, 1 hit
PF02210, Laminin_G_2, 2 hits
PF01740, STAS, 1 hit
PF00916, Sulfate_transp, 1 hit
PRINTSiPR00205, CADHERIN
PR00249, GPCRSECRETIN
SMARTiView protein in SMART
SM00112, CA, 9 hits
SM00181, EGF, 6 hits
SM00179, EGF_CA, 5 hits
SM00180, EGF_Lam, 1 hit
SM00303, GPS, 1 hit
SM00008, HormR, 1 hit
SM00282, LamG, 2 hits
SUPFAMiSSF49313, SSF49313, 9 hits
SSF49899, SSF49899, 2 hits
SSF52091, SSF52091, 1 hit
TIGRFAMsiTIGR00815, sulP, 1 hit
PROSITEiView protein in PROSITE
PS00232, CADHERIN_1, 6 hits
PS00022, EGF_1, 4 hits
PS01186, EGF_2, 3 hits
PS50026, EGF_3, 6 hits
PS01248, EGF_LAM_1, 1 hit
PS50027, EGF_LAM_2, 1 hit
PS00650, G_PROTEIN_RECEP_F2_2, 1 hit
PS50227, G_PROTEIN_RECEP_F2_3, 1 hit
PS50261, G_PROTEIN_RECEP_F2_4, 1 hit
PS50221, GPS, 1 hit
PS50025, LAM_G_DOMAIN, 2 hits
PS01130, SLC26A, 1 hit
PS50801, STAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5Y190_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5Y190
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: October 7, 2020
This is version 127 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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