We will be switching to the new UniProt website soon. Please explore and share your feedback.
Take me to the new website.
UniProtKB - Q5XZF2 (Q5XZF2_MOUSE)
Protein
C-C motif chemokine
Gene
Ccl5
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- chemokine activity Source: InterPro
GO - Biological processi
- immune response Source: InterPro
Keywordsi
Molecular function | CytokineUniRule annotationARBA annotation |
Biological process | ChemotaxisUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: C-C motif chemokineUniRule annotation |
Gene namesi | Name:Ccl5Imported |
Organismi | Mus musculus (Mouse)Imported |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Organism-specific databases
MGIi | MGI:98262, Ccl5 |
VEuPathDBi | HostDB:ENSMUSG00000035042 |
Subcellular locationi
Extracellular region or secreted
- Secreted UniRule annotation
Extracellular region or secreted
- extracellular space Source: UniProtKB-KW
Keywords - Cellular componenti
SecretedUniRule annotationPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 23 | UniRule annotationAdd BLAST | 23 | |
ChainiPRO_5014205910 | 24 – 91 | C-C motif chemokineUniRule annotationAdd BLAST | 68 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000035042, Expressed in blood and 135 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 30 – 88 | SCYInterPro annotationAdd BLAST | 59 |
Sequence similaritiesi
Keywords - Domaini
SignalUniRule annotationPhylogenomic databases
HOGENOMi | CLU_141716_4_2_1 |
OMAi | HIQEYFY |
OrthoDBi | 1575018at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR039809, Chemokine_b/g/d IPR000827, Chemokine_CC_CS IPR001811, Chemokine_IL8-like_dom IPR036048, Interleukin_8-like_sf |
PANTHERi | PTHR12015, PTHR12015, 1 hit |
Pfami | View protein in Pfam PF00048, IL8, 1 hit |
SMARTi | View protein in SMART SM00199, SCY, 1 hit |
SUPFAMi | SSF54117, SSF54117, 1 hit |
PROSITEi | View protein in PROSITE PS00472, SMALL_CYTOKINES_CC, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5XZF2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKISAAALTI ILTAAALCTP APASPYGSDT TPCCFAYLSL ALPRAHVKEY
60 70 80 90
FYTSSKCSNL AVVFVTRRNR QVCANPEKKW VQEYINYLEM S
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY722103 mRNA Translation: AAU43779.1 CT010315 mRNA Translation: CAJ18523.1 |
RefSeqi | NP_038681.2, NM_013653.3 |
Genome annotation databases
GeneIDi | 20304 |
KEGGi | mmu:20304 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AY722103 mRNA Translation: AAU43779.1 CT010315 mRNA Translation: CAJ18523.1 |
RefSeqi | NP_038681.2, NM_013653.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protocols and materials databases
Antibodypediai | 73329, 935 antibodies from 40 providers |
DNASUi | 20304 |
Genome annotation databases
GeneIDi | 20304 |
KEGGi | mmu:20304 |
Organism-specific databases
CTDi | 6352 |
MGIi | MGI:98262, Ccl5 |
VEuPathDBi | HostDB:ENSMUSG00000035042 |
Phylogenomic databases
HOGENOMi | CLU_141716_4_2_1 |
OMAi | HIQEYFY |
OrthoDBi | 1575018at2759 |
Miscellaneous databases
BioGRID-ORCSi | 20304, 1 hit in 66 CRISPR screens |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000035042, Expressed in blood and 135 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR039809, Chemokine_b/g/d IPR000827, Chemokine_CC_CS IPR001811, Chemokine_IL8-like_dom IPR036048, Interleukin_8-like_sf |
PANTHERi | PTHR12015, PTHR12015, 1 hit |
Pfami | View protein in Pfam PF00048, IL8, 1 hit |
SMARTi | View protein in SMART SM00199, SCY, 1 hit |
SUPFAMi | SSF54117, SSF54117, 1 hit |
PROSITEi | View protein in PROSITE PS00472, SMALL_CYTOKINES_CC, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5XZF2_MOUSE | |
Accessioni | Q5XZF2Primary (citable) accession number: Q5XZF2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | January 19, 2022 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |