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Entry version 105 (31 Jul 2019)
Sequence version 1 (23 Nov 2004)
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Protein
Submitted name:

Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase

Gene

cad

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section is used for enzymes and indicates the residues directly involved in catalysis.<p><a href='/help/act_site' target='_top'>More...</a></p>Active sitei252NucleophilePROSITE-ProRule annotation1
Active sitei336PROSITE-ProRule annotation1
Active sitei338PROSITE-ProRule annotation1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandATP-bindingPROSITE-ProRule annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotaseImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:cadImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-021030-4 cad

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini177 – 363Glutamine amidotransferase type-1InterPro annotationAdd BLAST187
Domaini521 – 713ATP-graspInterPro annotationAdd BLAST193
Domaini1057 – 1248ATP-graspInterPro annotationAdd BLAST192

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1841 – 1877DisorderedSequence analysisAdd BLAST37

Keywords - Domaini

Glutamine amidotransferasePROSITE-ProRule annotation

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0370 Eukaryota
COG0458 LUCA
COG0505 LUCA
COG0540 LUCA

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000234584

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5XLV0

Family and domain databases

Conserved Domains Database

More...
CDDi
cd01744 GATase1_CPSase, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1030.10, 1 hit
3.30.1490.20, 1 hit
3.40.50.1370, 2 hits
3.40.50.1380, 1 hit
3.40.50.880, 1 hit
3.50.30.20, 1 hit

HAMAP database of protein families

More...
HAMAPi
MF_00001 Asp_carb_tr, 1 hit
MF_01209 CPSase_S_chain, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006680 Amidohydro-rel
IPR006132 Asp/Orn_carbamoyltranf_P-bd
IPR006130 Asp/Orn_carbamoylTrfase
IPR036901 Asp/Orn_carbamoylTrfase_sf
IPR002082 Asp_carbamoyltransf
IPR006131 Asp_carbamoyltransf_Asp/Orn-bd
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR006275 CarbamoylP_synth_lsu
IPR005480 CarbamoylP_synth_lsu_oligo
IPR036897 CarbamoylP_synth_lsu_oligo_sf
IPR006274 CarbamoylP_synth_ssu
IPR002474 CarbamoylP_synth_ssu_N
IPR036480 CarbP_synth_ssu_N_sf
IPR005479 CbamoylP_synth_lsu-like_ATP-bd
IPR005483 CbamoylP_synth_lsu_CPSase_dom
IPR029062 Class_I_gatase-like
IPR035686 CPSase_GATase1
IPR002195 Dihydroorotase_CS
IPR017926 GATASE
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
IPR016185 PreATP-grasp_dom_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01979 Amidohydro_1, 1 hit
PF02786 CPSase_L_D2, 2 hits
PF02787 CPSase_L_D3, 1 hit
PF00988 CPSase_sm_chain, 1 hit
PF00117 GATase, 1 hit
PF02142 MGS, 1 hit
PF00185 OTCace, 1 hit
PF02729 OTCace_N, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00100 AOTCASE
PR00098 CPSASE

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM01096 CPSase_L_D3, 1 hit
SM01097 CPSase_sm_chain, 1 hit
SM00851 MGS, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48108 SSF48108, 1 hit
SSF51338 SSF51338, 1 hit
SSF51556 SSF51556, 1 hit
SSF52021 SSF52021, 1 hit
SSF52317 SSF52317, 1 hit
SSF52335 SSF52335, 1 hit
SSF52440 SSF52440, 2 hits
SSF53671 SSF53671, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00670 asp_carb_tr, 1 hit
TIGR01369 CPSaseII_lrg, 1 hit
TIGR01368 CPSaseIIsmall, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50975 ATP_GRASP, 2 hits
PS00097 CARBAMOYLTRANSFERASE, 1 hit
PS00866 CPSASE_1, 2 hits
PS00867 CPSASE_2, 2 hits
PS00482 DIHYDROOROTASE_1, 1 hit
PS00483 DIHYDROOROTASE_2, 1 hit
PS51273 GATASE_TYPE_1, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5XLV0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASLVLEDGT TFKGRLFGAV SSVSGEVVFQ TGMVGYPEAL TDPSYKSQIL
60 70 80 90 100
TLTYPMIGNY GIPKDEDGEF GLSKWFESSQ IHAAALIVGE VSENPSHWSA
110 120 130 140 150
AKSLDEWLRE QGIPGLQGVD TRCLTKKIRE KGTMLGKLVV EGTPADNIPF
160 170 180 190 200
DNPDARNLVK EVSMKAPKVF NPEGTVRITA IDCGIKYNQI RCLCQRGARV
210 220 230 240 250
TVVPWDQPLD SNDFDGLFIS NGPGNPEYCK ETVENIRKVA CVENPKPIFG
260 270 280 290 300
ICLGHQLLSL VIGAKTYKMK YGNRGHNQPC IHKGTSRCYI TSQNHGFAVD
310 320 330 340 350
PETLPKDWDV LFTNANDQTS EGIVHNHKPL FSVQFHPEHM AGPTDLVGLF
360 370 380 390 400
DVFLDTVRDV KENKAGKSGD LTVKQRLMEH LTFPGSPDPN AFVRPRKVLV
410 420 430 440 450
LGSGGLSIGQ AGEFDYSGSQ AIKAMKEENI QTILINPNIA TVQTSKGLAD
460 470 480 490 500
KVYFLPITPE YVTQVIKNER PDGVLLTFGG QTALNCGVEL KKQGVLEKYK
510 520 530 540 550
VRVLGTPVAS IEMTEDRKIF VEKMEEINEH VAPSEAAMSV EQAVAAAERL
560 570 580 590 600
GYPVLVRSAF ALGGLGSGFA NNRDEMITLV TQAFAHTSQV LVDKSLKGWK
610 620 630 640 650
EIEYEVVRDA YDNCVTVCNM ENIDPLGIHT GESIVVAPSQ TLNDYEYNML
660 670 680 690 700
RNTAIKVIRH LGVVGECNIQ YALNPESEQY YIIEVNARLS RSSALASKAT
710 720 730 740 750
GYPLAYVAAK LSLGIPLPVL KNSVTNSTTA NFEPSLDYCV VKVPRWDLSK
760 770 780 790 800
FLRVSTKIGS SMKSVGEVMA IGRSFEEAFQ KALRMVDENC VGFDHTIKPE
810 820 830 840 850
SEEELQTPTD KRIFVLAAAL HAGYTVERLY ELTKIDHWFL HKMKNIADHK
860 870 880 890 900
KLLETYKQDE SAMPPEIMRK AKQLGFSDKQ IAQAVQSTEL AVRKLRRDWK
910 920 930 940 950
IFPVVKQIDT VAAEWPAQTN YLYLTYHGSE SDVVFEQPHV MVIGSGVYRI
960 970 980 990 1000
GSSVEFDWCA VGCIMELRKM GYKTIMVNYN PETVSTDYDM CDRLYFDEIS
1010 1020 1030 1040 1050
FEVVMDIYEM ENPEGVILSM GGQLPNNIAM SLHRQQCRIL GTSPEFIDNA
1060 1070 1080 1090 1100
ENRFKFSRML DTIGISQPRW KELSDTESAV NFCETVGYPC LVRPSYVLSG
1110 1120 1130 1140 1150
AAMNVAYSDT DMEKFLSSAV AVSKEHPVVI SKFIQEAKEI DVDAVACDGE
1160 1170 1180 1190 1200
VIAIAVSEHV ENAGVHSGDA TLVTPPQDIN QKTMERIKMI VHAIGQELQV
1210 1220 1230 1240 1250
TGPFNLQLIA KDDQLKVIEC NVRVSRSFPY VSKTLGVDLV ALATRVILGE
1260 1270 1280 1290 1300
EVEAVGLMRG NGIVGVKVPQ FSFSRLAGAD VVLGVEMTST GEVACFGENR
1310 1320 1330 1340 1350
YEAYLKAMLS TGFKIPKKNI LLSIGSYKNK SELLPTVQTL ESLGYNLYAS
1360 1370 1380 1390 1400
LGTADFYTEH GVKVMAVDWP FEEESDCPNK DKQRNIMDYL EENHFDLVIN
1410 1420 1430 1440 1450
LSMRNSGGRR LSSFVTKGYR TRRMAIDFSV PLITDIKCTK LFVQALKQIG
1460 1470 1480 1490 1500
QAPRVKTHVD SMTSQKLIRL PGLIDVHVHL REPGATHKED FSSGTAAALA
1510 1520 1530 1540 1550
GGITMVCAMP NTNPAIIDPN SFTMAQKLAK AGCRCDYALF VGASSDNAAL
1560 1570 1580 1590 1600
LPSIASSTAG LKMYLNDTYS TLKMDNVSLW MEHFEKWPKH LPIVAHAEKQ
1610 1620 1630 1640 1650
TVAAILLVAQ LYQRPVHICH VAKKEEILII RAAKQKGIQV TCEVAPHHLF
1660 1670 1680 1690 1700
LCEDNVPVIG KDKAQVRPML GTREDMEALW ENLDIIDCFA TDHAPHSAEE
1710 1720 1730 1740 1750
KISEKPPPGY PGLETMLPLL FTAVSEGRLT VDDIIKRLYE NPRKIFSLPA
1760 1770 1780 1790 1800
QEDTYVEVDL EQEWIIPKHM QFTKSKWTPF EGMKVKGKVM RVVLRGEVAY
1810 1820 1830 1840 1850
IDGQVLVPPG YGQDVKSWSA TPTATTEVIM DAPKRVIEAM TPERPRQAAP
1860 1870 1880 1890 1900
VDAVRSRAPS PRRSAGDGRF ILPPRIHRSS DPGLPPELAL PAEAYAHPPP
1910 1920 1930 1940 1950
LARILSPQAG QPQILPHPQT SPLLHPLVGQ HILSVRQFSK EQMSHLFNVA
1960 1970 1980 1990 2000
HTLRLMVQKE RPLDILKGKV MASMFYEVST RTSSSFAAAM HRLGGSVVHF
2010 2020 2030 2040 2050
CESTSSTQKG ESLVDSVNTM SCYADVIVLR HPIPGAVESA ARHCRRPVIN
2060 2070 2080 2090 2100
AGDGVGEHPT QALLDIFTIR EELGTVNGMT ITMVGDLKHG RTVHSLARLL
2110 2120 2130 2140 2150
TQYRITLRYV APKNLSMPAE IIDFVASKGI KQEEFNSIEE ALPDTDVLYM
2160 2170 2180 2190 2200
TRIQKERFSS EKEYNACFGQ FILTPHIMTG AKRKMVVMHP LPRVNEISVE
2210 2220 2230
VDTDPRAAYF RQAENGMYIR MALLATVLGR
Length:2,230
Mass (Da):247,202
Last modified:November 23, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3DD1D86F55F0D16C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY751464 mRNA Translation: AAU95538.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY751464 mRNA Translation: AAU95538.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Organism-specific databases

ZFINiZDB-GENE-021030-4 cad

Phylogenomic databases

eggNOGiKOG0370 Eukaryota
COG0458 LUCA
COG0505 LUCA
COG0540 LUCA
HOGENOMiHOG000234584
PhylomeDBiQ5XLV0

Family and domain databases

CDDicd01744 GATase1_CPSase, 1 hit
Gene3Di1.10.1030.10, 1 hit
3.30.1490.20, 1 hit
3.40.50.1370, 2 hits
3.40.50.1380, 1 hit
3.40.50.880, 1 hit
3.50.30.20, 1 hit
HAMAPiMF_00001 Asp_carb_tr, 1 hit
MF_01209 CPSase_S_chain, 1 hit
InterProiView protein in InterPro
IPR006680 Amidohydro-rel
IPR006132 Asp/Orn_carbamoyltranf_P-bd
IPR006130 Asp/Orn_carbamoylTrfase
IPR036901 Asp/Orn_carbamoylTrfase_sf
IPR002082 Asp_carbamoyltransf
IPR006131 Asp_carbamoyltransf_Asp/Orn-bd
IPR011761 ATP-grasp
IPR013815 ATP_grasp_subdomain_1
IPR006275 CarbamoylP_synth_lsu
IPR005480 CarbamoylP_synth_lsu_oligo
IPR036897 CarbamoylP_synth_lsu_oligo_sf
IPR006274 CarbamoylP_synth_ssu
IPR002474 CarbamoylP_synth_ssu_N
IPR036480 CarbP_synth_ssu_N_sf
IPR005479 CbamoylP_synth_lsu-like_ATP-bd
IPR005483 CbamoylP_synth_lsu_CPSase_dom
IPR029062 Class_I_gatase-like
IPR035686 CPSase_GATase1
IPR002195 Dihydroorotase_CS
IPR017926 GATASE
IPR011059 Metal-dep_hydrolase_composite
IPR032466 Metal_Hydrolase
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
IPR016185 PreATP-grasp_dom_sf
PfamiView protein in Pfam
PF01979 Amidohydro_1, 1 hit
PF02786 CPSase_L_D2, 2 hits
PF02787 CPSase_L_D3, 1 hit
PF00988 CPSase_sm_chain, 1 hit
PF00117 GATase, 1 hit
PF02142 MGS, 1 hit
PF00185 OTCace, 1 hit
PF02729 OTCace_N, 1 hit
PRINTSiPR00100 AOTCASE
PR00098 CPSASE
SMARTiView protein in SMART
SM01096 CPSase_L_D3, 1 hit
SM01097 CPSase_sm_chain, 1 hit
SM00851 MGS, 1 hit
SUPFAMiSSF48108 SSF48108, 1 hit
SSF51338 SSF51338, 1 hit
SSF51556 SSF51556, 1 hit
SSF52021 SSF52021, 1 hit
SSF52317 SSF52317, 1 hit
SSF52335 SSF52335, 1 hit
SSF52440 SSF52440, 2 hits
SSF53671 SSF53671, 1 hit
TIGRFAMsiTIGR00670 asp_carb_tr, 1 hit
TIGR01369 CPSaseII_lrg, 1 hit
TIGR01368 CPSaseIIsmall, 1 hit
PROSITEiView protein in PROSITE
PS50975 ATP_GRASP, 2 hits
PS00097 CARBAMOYLTRANSFERASE, 1 hit
PS00866 CPSASE_1, 2 hits
PS00867 CPSASE_2, 2 hits
PS00482 DIHYDROOROTASE_1, 1 hit
PS00483 DIHYDROOROTASE_2, 1 hit
PS51273 GATASE_TYPE_1, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiQ5XLV0_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5XLV0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: November 23, 2004
Last sequence update: November 23, 2004
Last modified: July 31, 2019
This is version 105 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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