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Entry version 60 (29 Sep 2021)
Sequence version 1 (23 Nov 2004)
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Protein

Protein KATNIP homolog

Gene
N/A
Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

May control cilium integrity.

By similarity

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein KATNIP homolog
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus laevis (African clawed frog)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8355 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-5819675, katnip.L

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell projection, Cytoplasm, Cytoskeleton

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00003130921 – 1414Protein KATNIP homologAdd BLAST1414

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
104930, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q5XK85, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 32DisorderedSequence analysisAdd BLAST32
Regioni80 – 116DisorderedSequence analysisAdd BLAST37
Regioni139 – 158DisorderedSequence analysisAdd BLAST20
Regioni712 – 731DisorderedSequence analysisAdd BLAST20
Regioni756 – 783DisorderedSequence analysisAdd BLAST28
Regioni823 – 861DisorderedSequence analysisAdd BLAST39
Regioni924 – 943DisorderedSequence analysisAdd BLAST20

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi831 – 848Polar residuesSequence analysisAdd BLAST18
Compositional biasi924 – 942Polar residuesSequence analysisAdd BLAST19

Phylogenomic databases

Identification of Orthologs from Complete Genome Data

More...
OMAi
FVDYLQP

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR026704, KATNIP
IPR027859, KATNIP_dom

The PANTHER Classification System

More...
PANTHERi
PTHR21534, PTHR21534, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF14652, DUF4457, 5 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5XK85-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MHGKSLGSSR KNDSRSKIRQ EKESNIDFDE KHDEYLINLQ QRNRALNNSK
60 70 80 90 100
AKDATQIKLQ HLEEGFSLYL NGANADLRKQ QSTQDLARES SKSSKIPDDG
110 120 130 140 150
CSHLPGRRSQ TAPGKIQRKA WVQNSIQIKS ERGSRVYIGP NTKYSEDFES
160 170 180 190 200
DDDMNEDQAS DQYKYFTDSE KNVPQGPGKK RLVLDASDVK ALRESLEISL
210 220 230 240 250
CLQQDSKYSL DDDDADFVEE ELIECETPEL DSPSKTQLES KHQAFGHQRL
260 270 280 290 300
LPGDFVVLEF NALDKKDGRM LTAKRKDNSE FYIPTKPVMV KNKTPRLKSS
310 320 330 340 350
SFSSKDSFFP RPESRQEILL PTPRRSISEN KDSRPSVSTV VDAINNENEA
360 370 380 390 400
ITRAISDGKT EKMTSGPSGI SEGVVTKAIE KINLMKISQQ KKLLKVLQDI
410 420 430 440 450
DNDSSTNSNS EGEILKWDSV YLDPAVKDVI CITVEILSNW GNQYYIGLTE
460 470 480 490 500
IQFFDLKNEE IYVSPHDVDI RNVDVPGDPT CLVNGKTLTT KEHFMWTCPF
510 520 530 540 550
HPPVQLYFII RNATKSGDFD ISKMKIWNYN KALSDLDIGA KLVKIYKDET
560 570 580 590 600
LVFDGLLAKG SGNQDFDYSN TIDLHSGQIK SSSFISDQFS DETQISNSLG
610 620 630 640 650
ASNNIELKHQ SDGLVYTSEQ LSSILSEGSN QAKTSQQKDL HFENNTKGLR
660 670 680 690 700
TFQDEALNKS FQHLALTSSS INCQEDITEG EVGIKMSYNK EEHFKINQSK
710 720 730 740 750
DFNTMTAELQ MVSATSSKEP PPCPRDDNDL TVTDQLERTP GRKECSSLNR
760 770 780 790 800
FPPWLSSSSN FQQKSHNQPT KNHLNASSST FTNKRSDQDI NQFLDEYVKS
810 820 830 840 850
SNTYSNKNFK NCSQSKMLCS SSKMDNEDDL ENFSNQSSYN SDRPVSGRRK
860 870 880 890 900
TVQMQDKSEK YEGASFHKTI NPVDTKNLRP RWQNDQENNL LESWTSLIKF
910 920 930 940 950
NKSHRGRISN LEFEGDIFDE FLQQQQKAGK QSDSTKNGSS LMPKGATEIH
960 970 980 990 1000
LESEKEEGSN FEIPVLPYGQ HLCIKIVTTW GDRHYVGLNG IEVFASTGKP
1010 1020 1030 1040 1050
VEISRIRADP PDINILPAYG KDPRVVVNLI DGVNRTQDDM HLWLAPFSPG
1060 1070 1080 1090 1100
KLHFINLDFV EPCRVAMIRI WNYNKSRIHS FRGVKEVEIF LDNELIFKGE
1110 1120 1130 1140 1150
IAKASGTLSG AAEQFGDTIL FTTDDEILQA MSLFDETFSE ELKATETPTE
1160 1170 1180 1190 1200
HEIDSLRPST ADSIKEERPF TQAGLSEKLQ SNLTDVSENY SDKLPGIYSG
1210 1220 1230 1240 1250
KCLLLNFTMT WGDPHYLGLT GMEIVGRDGK ALAITLDALS ACPQDLSILP
1260 1270 1280 1290 1300
EYKDDLRTLD KLIDGVNITN EDTHMWLIPF ASGADHTITI NFNKSEDIAG
1310 1320 1330 1340 1350
IRFWNYNKSP EDTYRGAKIV YVTLDGHAIS PPGGFLIRKG PGNCHFDFAQ
1360 1370 1380 1390 1400
EILFVDYIHE QQILEKQLRS HSKCMELATM DYEAPLMPCG FIFQLQLITS
1410
WGDPYYIGLN GLEM
Length:1,414
Mass (Da):159,672
Last modified:November 23, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD9E35F9BF6DC2162
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC083029 mRNA Translation: AAH83029.1

NCBI Reference Sequences

More...
RefSeqi
NP_001088144.1, NM_001094675.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
494850

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xla:494850

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC083029 mRNA Translation: AAH83029.1
RefSeqiNP_001088144.1, NM_001094675.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi104930, 1 interactor
IntActiQ5XK85, 1 interactor

Genome annotation databases

GeneIDi494850
KEGGixla:494850

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
494850
XenbaseiXB-GENE-5819675, katnip.L

Phylogenomic databases

OMAiFVDYLQP

Family and domain databases

InterProiView protein in InterPro
IPR026704, KATNIP
IPR027859, KATNIP_dom
PANTHERiPTHR21534, PTHR21534, 1 hit
PfamiView protein in Pfam
PF14652, DUF4457, 5 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiKATIP_XENLA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5XK85
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 23, 2004
Last modified: September 29, 2021
This is version 60 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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