UniProtKB - Q5XIA5 (Q5XIA5_RAT)
Protein
Submitted name:
Coenzyme A synthase
Gene
Coasy
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- ATP binding Source: UniProtKB-KW
- dephospho-CoA kinase activity Source: RGD
- pantetheine-phosphate adenylyltransferase activity Source: RGD
GO - Biological processi
- coenzyme A biosynthetic process Source: RGD
Keywordsi
Ligand | ATP-bindingARBA annotation, Nucleotide-binding |
Enzyme and pathway databases
Reactomei | R-RNO-196783, Coenzyme A biosynthesis |
Names & Taxonomyi
Protein namesi | Submitted name: Coenzyme A synthaseImported |
Gene namesi | Name:CoasyImported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 1549767, Coasy |
Subcellular locationi
Mitochondrion
- mitochondrial matrix Source: RGD
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Signal peptidei | 1 – 19 | Sequence analysisAdd BLAST | 19 | |
ChainiPRO_5014310184 | 20 – 563 | Sequence analysisAdd BLAST | 544 |
Proteomic databases
PRIDEi | Q5XIA5 |
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000019918, Expressed in brain and 22 other tissues |
Interactioni
Protein-protein interaction databases
IntActi | Q5XIA5, 5 interactors |
STRINGi | 10116.ENSRNOP00000027061 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 195 – 338 | CTP_transf_likeInterPro annotationAdd BLAST | 144 |
Keywords - Domaini
SignalSequence analysisPhylogenomic databases
eggNOGi | KOG3220, Eukaryota KOG3351, Eukaryota |
GeneTreei | ENSGT00550000075078 |
HOGENOMi | CLU_027827_1_0_1 |
OMAi | VIDCDKV |
OrthoDBi | 1543581at2759 |
TreeFami | TF105783 |
Family and domain databases
Gene3Di | 3.40.50.620, 1 hit |
HAMAPi | MF_00376, Dephospho_CoA_kinase, 1 hit |
InterProi | View protein in InterPro IPR004821, Cyt_trans-like IPR001977, Depp_CoAkinase IPR027417, P-loop_NTPase IPR014729, Rossmann-like_a/b/a_fold |
Pfami | View protein in Pfam PF01121, CoaE, 1 hit PF01467, CTP_transf_like, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00152, TIGR00152, 1 hit |
PROSITEi | View protein in PROSITE PS51219, DPCK, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5XIA5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAVFRSGLLV LTTPLATLAA RLPPILTSAS HLVNHTLYVH LQPGMNLGGP
60 70 80 90 100
AQPQPSPVQA TFEVLDFITH LYTGADLHRH LDVRILLTNI QTKSTLIPVL
110 120 130 140 150
SSVQNLAHPP EVVLTDFQTL DGSQYNPVKQ QLERYATSCY SCSPQLSSVL
160 170 180 190 200
LYPDYGTGEM PLELPNALLP STIRPASPVA RSPRQPVRGY RRGAVGGTFD
210 220 230 240 250
RLHNAHKVLL SVACVLAQEQ LVVGVADKDL LKSKLLPELL QPYSERVGHL
260 270 280 290 300
NEFLVDIKPS LTFELIPLLD PYGPAGSDPT LEFLVVSEET YRGGMAVNRF
310 320 330 340 350
RLENGKEELA LYQIQLLKDQ SHKENEEEKV SSSSFRQRIL GNLLQPPNER
360 370 380 390 400
PELPSGIYVL GLTGISGSGK SSVAQRLKNL GAYIIDSDHL GHRAYAPGGP
410 420 430 440 450
AYQPVVEAFG TDILHQDGTI NRKVLGSRVF GNKKQLKMLT DIVWPVIAKL
460 470 480 490 500
AREEMDVAVA KGKTLCVIDA AMLLEAGWQN MVHEVWTVVI PESEAVRRIV
510 520 530 540 550
ERDGLSEAAA QSRLQNQMSG QQLVEQSHVV LCTLWESHVT QRQVEKAWDL
560
LQKRLPKAHQ TRN
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07072184 Genomic DNA No translation available. BC083781 mRNA Translation: AAH83781.1 |
RefSeqi | NP_001006955.1, NM_001006954.1 XP_006247338.1, XM_006247276.3 |
Genome annotation databases
Ensembli | ENSRNOT00000027061; ENSRNOP00000027061; ENSRNOG00000019918 |
GeneIDi | 287711 |
KEGGi | rno:287711 |
UCSCi | RGD:1549767, rat |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07072184 Genomic DNA No translation available. BC083781 mRNA Translation: AAH83781.1 |
RefSeqi | NP_001006955.1, NM_001006954.1 XP_006247338.1, XM_006247276.3 |
3D structure databases
SMRi | Q5XIA5 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q5XIA5, 5 interactors |
STRINGi | 10116.ENSRNOP00000027061 |
Proteomic databases
PRIDEi | Q5XIA5 |
Genome annotation databases
Ensembli | ENSRNOT00000027061; ENSRNOP00000027061; ENSRNOG00000019918 |
GeneIDi | 287711 |
KEGGi | rno:287711 |
UCSCi | RGD:1549767, rat |
Organism-specific databases
CTDi | 80347 |
RGDi | 1549767, Coasy |
Phylogenomic databases
eggNOGi | KOG3220, Eukaryota KOG3351, Eukaryota |
GeneTreei | ENSGT00550000075078 |
HOGENOMi | CLU_027827_1_0_1 |
OMAi | VIDCDKV |
OrthoDBi | 1543581at2759 |
TreeFami | TF105783 |
Enzyme and pathway databases
Reactomei | R-RNO-196783, Coenzyme A biosynthesis |
Gene expression databases
Bgeei | ENSRNOG00000019918, Expressed in brain and 22 other tissues |
Family and domain databases
Gene3Di | 3.40.50.620, 1 hit |
HAMAPi | MF_00376, Dephospho_CoA_kinase, 1 hit |
InterProi | View protein in InterPro IPR004821, Cyt_trans-like IPR001977, Depp_CoAkinase IPR027417, P-loop_NTPase IPR014729, Rossmann-like_a/b/a_fold |
Pfami | View protein in Pfam PF01121, CoaE, 1 hit PF01467, CTP_transf_like, 1 hit |
SUPFAMi | SSF52540, SSF52540, 1 hit |
TIGRFAMsi | TIGR00152, TIGR00152, 1 hit |
PROSITEi | View protein in PROSITE PS51219, DPCK, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5XIA5_RAT | |
Accessioni | Q5XIA5Primary (citable) accession number: Q5XIA5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 23, 2004 |
Last sequence update: | November 23, 2004 | |
Last modified: | February 10, 2021 | |
This is version 141 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |