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Entry version 54 (02 Jun 2021)
Sequence version 1 (23 Nov 2004)
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Protein

Nucleolar complex protein 3 homolog

Gene

noc3l

Organism
Xenopus laevis (African clawed frog)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Nucleolar complex protein 3 homolog
Short name:
NOC3 protein homolog
Alternative name(s):
NOC3-like protein
Nucleolar complex-associated protein 3-like protein
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:noc3l
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiXenopus laevis (African clawed frog)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri8355 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

Xenopus laevis and tropicalis biology and genomics resource

More...
Xenbasei
XB-GENE-5957788, noc3l.S

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00001734781 – 795Nucleolar complex protein 3 homologAdd BLAST795

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGRID)

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BioGRIDi
105185, 1 interactor

Protein interaction database and analysis system

More...
IntActi
Q5XGZ8, 1 interactor

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 88DisorderedSequence analysisAdd BLAST88
Regioni124 – 144DisorderedSequence analysisAdd BLAST21
Regioni168 – 190DisorderedSequence analysisAdd BLAST23

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili447 – 492Sequence analysisAdd BLAST46

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular type of amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi18 – 76Basic and acidic residuesSequence analysisAdd BLAST59
Compositional biasi171 – 186Acidic residuesSequence analysisAdd BLAST16

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the CBF/MAK21 family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
341721at2759

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR016024, ARM-type_fold
IPR005612, CCAAT-binding_factor
IPR011501, Noc3_N
IPR016903, Nucleolar_cplx-assoc_3

The PANTHER Classification System

More...
PANTHERi
PTHR14428, PTHR14428, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF03914, CBF, 1 hit
PF07540, NOC3p, 1 hit

PIRSF; a whole-protein classification database

More...
PIRSFi
PIRSF028977, Nucleolar_complex_p3, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48371, SSF48371, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

Q5XGZ8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKPMRNRKQA PSFRKLLKTS KLKLDNKLKN KQFKQESSAK KRRKEQKQLR
60 70 80 90 100
EAVRDVRSKI PKPLETVKKK QPVEEEYEVE EESLPLDMMD EDDVQLMKEM
110 120 130 140 150
AQRASFLTRD LTYSEPVHAN KRKRDDVINK YEKMPRKSKS EPEKEVIHLL
160 170 180 190 200
PIKDRHGIIP QTMEKPVIPS EEQEENEEEM DTEHTEEVPE EPLRIMTTEE
210 220 230 240 250
LLVHRQVTLE QRKTHIATLA SAILSEPENN IRKLKELRSM LMEQDPSVAV
260 270 280 290 300
TVRKLVMLSL MEVFKDITPS YKIRPLTEAE KAARVKKDTQ KLREFEEGLI
310 320 330 340 350
SQYKFYLENL EQILKDWKQM KTKKSEVVSL HAYKGLAEIA VKCLCELMVS
360 370 380 390 400
LSHFNFHNNI IVLVVPLVND KCRQISELSM EATRKLFRQD KFGHASLAAV
410 420 430 440 450
KVISGLVKSR NYDVRPEVLQ LLLHLRIKEV EVKKDTEDIA PKQKIMSYKD
460 470 480 490 500
KKKNLSRMQR KWKKAEEKLE RELLEAEASE SKEKKLKLNT ETLNIVFLTY
510 520 530 540 550
FRILKRAQKS VLLPSVLEGL AKFAHLINVE FFDDLLIVLH KLIDSGDLTY
560 570 580 590 600
RESLHCVQTA FNILSGQGDV LNIDPLKFYT HLYKTLYGLH AGATNDDTLI
610 620 630 640 650
ALQCLDVMLT RRRRQVSQQR ALAFIKRLST LALHVLPDSS IGILSTNRVL
660 670 680 690 700
MQTFPKTDLL LDSDSQGSGI YLPELDEPEY CNAQNSALWE LHTLMRHYHP
710 720 730 740 750
VVQIFAAHLS AGAPSEGSGA LKAELSRRSA QELFADYSIK EMTFNPPVSE
760 770 780 790
SVPKRKTKSR AFDLSEDLEQ LIQAQLEKVS SLHVDFSSCI KAQSV
Length:795
Mass (Da):91,810
Last modified:November 23, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iD28240CFCF9FD41C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC084278 mRNA Translation: AAH84278.1

NCBI Reference Sequences

More...
RefSeqi
NP_001088273.1, NM_001094804.1

Genome annotation databases

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
495105

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
xla:495105

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC084278 mRNA Translation: AAH84278.1
RefSeqiNP_001088273.1, NM_001094804.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGRIDi105185, 1 interactor
IntActiQ5XGZ8, 1 interactor

Genome annotation databases

GeneIDi495105
KEGGixla:495105

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
495105
XenbaseiXB-GENE-5957788, noc3l.S

Phylogenomic databases

OrthoDBi341721at2759

Family and domain databases

InterProiView protein in InterPro
IPR016024, ARM-type_fold
IPR005612, CCAAT-binding_factor
IPR011501, Noc3_N
IPR016903, Nucleolar_cplx-assoc_3
PANTHERiPTHR14428, PTHR14428, 1 hit
PfamiView protein in Pfam
PF03914, CBF, 1 hit
PF07540, NOC3p, 1 hit
PIRSFiPIRSF028977, Nucleolar_complex_p3, 1 hit
SUPFAMiSSF48371, SSF48371, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiNOC3L_XENLA
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5XGZ8
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: September 27, 2005
Last sequence update: November 23, 2004
Last modified: June 2, 2021
This is version 54 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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