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UniProtKB - Q5WZW9 (Q5WZW9_LEGPL)
Protein
Non-specific serine/threonine protein kinase
Gene
lpl0262
Organism
Legionella pneumophila (strain Lens)
Status
Functioni
Catalytic activityi
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Binding sitei | 89 | ATP analogCombined sources | 1 | |
Binding sitei | 152 | ATP analogCombined sources | 1 | |
Binding sitei | 213 | ATP analogCombined sources | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Nucleotide bindingi | 102 – 104 | ATP analogCombined sources | 3 | |
Nucleotide bindingi | 146 – 148 | ATP analogCombined sources | 3 | |
Nucleotide bindingi | 199 – 202 | ATP analogCombined sources | 4 |
GO - Molecular functioni
- ATP binding Source: InterPro
- protein serine/threonine/tyrosine kinase activity Source: RHEA
- protein serine/threonine kinase activity Source: UniProtKB-EC
- protein serine kinase activity Source: RHEA
Keywordsi
Ligand | Nucleotide-bindingCombined sources |
Names & Taxonomyi
Protein namesi | Recommended name: Non-specific serine/threonine protein kinaseARBA annotation (EC:2.7.11.1ARBA annotation) |
Gene namesi | Ordered Locus Names:lpl0262Imported |
Organismi | Legionella pneumophila (strain Lens)Imported |
Taxonomic identifieri | 297245 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Legionellales › Legionellaceae › Legionella › |
Proteomesi |
|
Organism-specific databases
LegioListi | lpl0262 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 73 – 394 | Protein kinaseInterPro annotationAdd BLAST | 322 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 350 – 370 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
HOGENOMi | CLU_307506_0_0_6 |
OMAi | ANHEPRK |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5WZW9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKLLRFHELK SLPGMDEKAL ELLIKVLGNK GIRKLIKSAD GKPISREIMI
60 70 80 90 100
HEFGIDCQIL FITTEASLKP IIVPTENKIS GGGKSYCEQF KVYALDDGKT
110 120 130 140 150
YFLKSVKIDA ESLTEFTNEK DTLSKLGRLV GTFFNEQTQV HYILTTFIKG
160 170 180 190 200
IDLSRYKNAL PLNVNLKHFW EVLGIMISVC HQVKQFHELG LIHRDLKPGN
210 220 230 240 250
IMLDADMQCH LVDFGSSSSD KEPKPASWGT ASYLAPELNA QEDFIAFSQV
260 270 280 290 300
SDLFALAYSL DELFNPFRQV KFAKVDIGIK NKHLVLLHAE IEACITGLMS
310 320 330 340 350
NETSVRTLYF SRILQLQRVP ESFKSRPEAF TYLIMLLTQW KSCYEAPEMN
360 370 380 390 400
KELDEIIAEI KVAYENHEQD AVKIITLLEQ LSKADGLLNS HKALLSVLIK
410 420 430 440 450
SLANVQQQEL GHDDILPRRF ESDVVSRLIK TPTAKMMAAI KQVSDAIVKI
460 470 480 490 500
LEQYEHSPTE SFEYAVLQDF LEQMVQSDIL FGAPKEKIEI SDIIKILKAN
510 520 530 540 550
RPEDFVQIQH ISFKFAQVAL RDLALHDLPK YEPKGAFLEI LRKYQAKYAP
560 570 580 590 600
EETSLFELYH HMAGVRDHNP SKVKKGEGYR FRAFICDELF YGDEIFTTGD
610 620 630 640 650
NRGREGKPNQ RLQTNQVGLM KFEHSAHTKG LLTLNGQSWY ADCKTQLPNY
660 670 680 690 700
DSIHYLSALK TDCPYITGPS GMTSLFMNMM FLLLNPKDQD VILSYSLGVM
710 720 730 740 750
TYVVGAGYHS IKEILIPMVK CVGIVPDYPQ HKGTECLTAP PLYNHYFKAI
760 770 780 790 800
EEFDKEFAEA HEKIWQEYLA YFRMTYMPVC MRSHCLPHQV PSMEDISSEV
810 820 830 840 850
KEMLEIVSKS VKNCLEEHKV KRTGDMGLFL STPCGQTKAL EVLSHVCQQQ
860 870 880 890 900
VGLTAIFRQI QAYFKGTFET EEGIIINREM QLKFIAHFFD VLKESPTLLS
910 920 930 940 950
QFNLTLRIEN TIGVHQCELG SSKQKELFLE IKKTSIAANE EQMVANHEPR
960
KENRNVIILP Y
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR628337 Genomic DNA Translation: CAH14493.1 |
RefSeqi | WP_011214527.1, NC_006369.1 |
Genome annotation databases
EnsemblBacteriai | CAH14493; CAH14493; lpl0262 |
KEGGi | lpf:lpl0262 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR628337 Genomic DNA Translation: CAH14493.1 |
RefSeqi | WP_011214527.1, NC_006369.1 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5CKW | X-ray | 2.49 | A/B | 1-445 | [»] | |
5CLR | X-ray | 3.71 | A/B | 2-445 | [»] | |
SMRi | Q5WZW9 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Genome annotation databases
EnsemblBacteriai | CAH14493; CAH14493; lpl0262 |
KEGGi | lpf:lpl0262 |
Organism-specific databases
LegioListi | lpl0262 |
Phylogenomic databases
HOGENOMi | CLU_307506_0_0_6 |
OMAi | ANHEPRK |
Family and domain databases
InterProi | View protein in InterPro IPR011009, Kinase-like_dom_sf IPR000719, Prot_kinase_dom IPR008271, Ser/Thr_kinase_AS |
Pfami | View protein in Pfam PF00069, Pkinase, 1 hit |
SMARTi | View protein in SMART SM00220, S_TKc, 1 hit |
SUPFAMi | SSF56112, SSF56112, 1 hit |
PROSITEi | View protein in PROSITE PS50011, PROTEIN_KINASE_DOM, 1 hit PS00108, PROTEIN_KINASE_ST, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5WZW9_LEGPL | |
Accessioni | Q5WZW9Primary (citable) accession number: Q5WZW9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 23, 2004 |
Last sequence update: | November 23, 2004 | |
Last modified: | January 19, 2022 | |
This is version 107 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |