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Protein

Tetratricopeptide repeat protein 23

Gene

TTC23

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tetratricopeptide repeat protein 23
Short name:
TPR repeat protein 23
Alternative name(s):
Cervical cancer proto-oncogene 8 protein
Short name:
HCC-8
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TTC23
ORF Names:HCC8
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Eukaryotic Pathogen Database Resources

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EuPathDBi
HostDB:ENSG00000103852.12

Human Gene Nomenclature Database

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HGNCi
HGNC:25730 TTC23

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5W5X9

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

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OpenTargetsi
ENSG00000103852

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670675

Polymorphism and mutation databases

Domain mapping of disease mutations (DMDM)

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DMDMi
74708246

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002895481 – 447Tetratricopeptide repeat protein 23Add BLAST447

Proteomic databases

Encyclopedia of Proteome Dynamics

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EPDi
Q5W5X9

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5W5X9

PeptideAtlas

More...
PeptideAtlasi
Q5W5X9

PRoteomics IDEntifications database

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PRIDEi
Q5W5X9

ProteomicsDB human proteome resource

More...
ProteomicsDBi
65810
65811 [Q5W5X9-2]
65812 [Q5W5X9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

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iPTMneti
Q5W5X9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

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PhosphoSitePlusi
Q5W5X9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

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Bgeei
ENSG00000103852 Expressed in 138 organ(s), highest expression level in lower esophagus

CleanEx database of gene expression profiles

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CleanExi
HS_TTC23

ExpressionAtlas, Differential and Baseline Expression

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ExpressionAtlasi
Q5W5X9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

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Genevisiblei
Q5W5X9 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA039806
HPA040369

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

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BioGridi
122349, 22 interactors

Protein interaction database and analysis system

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IntActi
Q5W5X9, 94 interactors

Molecular INTeraction database

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MINTi
Q5W5X9

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

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ProteinModelPortali
Q5W5X9

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
Q5W5X9

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati45 – 78TPR 1Add BLAST34
Repeati137 – 170TPR 2Add BLAST34
Repeati186 – 219TPR 3Add BLAST34
Repeati356 – 389TPR 4Add BLAST34

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

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eggNOGi
ENOG410IJRU Eukaryota
ENOG410XVCY LUCA

Ensembl GeneTree

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GeneTreei
ENSGT00530000063847

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

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HOGENOMi
HOG000154704

The HOVERGEN Database of Homologous Vertebrate Genes

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HOVERGENi
HBG096816

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5W5X9

Identification of Orthologs from Complete Genome Data

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OMAi
PYNDNTD

Database of Orthologous Groups

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OrthoDBi
EOG091G08RQ

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5W5X9

TreeFam database of animal gene trees

More...
TreeFami
TF332604

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

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Gene3Di
1.25.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

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InterProi
View protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00028 TPR, 4 hits

Superfamily database of structural and functional annotation

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SUPFAMi
SSF48452 SSF48452, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5W5X9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQESQETHIS NHLDEVVAAV SITHRKKFQN KLLQTALFQP PREKLHLCEE
60 70 80 90 100
KAKSYSNSHE YKQAVHELVR CVALTRICYG DSHWKLAEAH VNLAQGYLQL
110 120 130 140 150
KGLSLQAKQH AEKARQILAN SIVPPYSENT DVFKFSIELF HTMGRALLSL
160 170 180 190 200
QKFKEAAENL TKAERLSKEL LQCGRIIKEE WIEIEARIRL SFAQVYQGQK
210 220 230 240 250
KSKEALSHYQ AALEYVEISK GETSRECVPI LRELAGVEQA LGLHDVSINH
260 270 280 290 300
FLQAHLIILS RSPSQVEAAD SAHIVAHAAV ASGRHEHHDV AEQYFQESMA
310 320 330 340 350
HLKDSEGMGR TKFLSIQDEF CHFLQMTGQK ERATSILRES LEAKVEAFGD
360 370 380 390 400
FSPEVAETYR LLGGADLAQG NHSGARKKLK KCLQIQTLLY GPQDKRTLAT
410 420 430 440
QQAMGMLSTA PKVASKPRQA SKAKVAFCTS IPQDTLLGKA RPGTTAD
Length:447
Mass (Da):50,009
Last modified:December 7, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7548138692B33E57
GO
Isoform 2 (identifier: Q5W5X9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     382-447: CLQIQTLLYG...GKARPGTTAD → VKLEPVLTRD

Show »
Length:391
Mass (Da):44,174
Checksum:i4D38FFBA005B3041
GO
Isoform 3 (identifier: Q5W5X9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     382-447: CLQIQTLLYG...GKARPGTTAD → GDLSFLLSATLP

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available.
Show »
Length:393
Mass (Da):44,238
Checksum:iA7C4AAC73EAA15A5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7BZG4H7BZG4_HUMAN
Tetratricopeptide repeat protein 23
TTC23
263Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YNH7H0YNH7_HUMAN
Tetratricopeptide repeat protein 23
TTC23
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YNV8H0YNV8_HUMAN
Tetratricopeptide repeat protein 23
TTC23
157Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YM10H0YM10_HUMAN
Tetratricopeptide repeat protein 23
TTC23
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YMN1H0YMN1_HUMAN
Tetratricopeptide repeat protein 23
TTC23
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YKN9H0YKN9_HUMAN
Tetratricopeptide repeat protein 23
TTC23
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YN45H0YN45_HUMAN
Tetratricopeptide repeat protein 23
TTC23
83Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YET0H0YET0_HUMAN
Tetratricopeptide repeat protein 23
TTC23
73Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB14144 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti374G → E in BAD96300 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026017382 – 447CLQIQ…GTTAD → VKLEPVLTRD in isoform 2. 1 PublicationAdd BLAST66
Alternative sequenceiVSP_026018382 – 447CLQIQ…GTTAD → GDLSFLLSATLP in isoform 3. 1 PublicationAdd BLAST66

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AF411456 mRNA Translation: AAQ03215.1
AK022634 mRNA Translation: BAB14144.1 Different initiation.
AK023230 mRNA Translation: BAB14480.1
AK222580 mRNA Translation: BAD96300.1
AK291690 mRNA Translation: BAF84379.1
BC015728 mRNA Translation: AAH15728.1

The Consensus CDS (CCDS) project

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CCDSi
CCDS10379.2 [Q5W5X9-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001275544.1, NM_001288615.1 [Q5W5X9-1]
NP_001275545.1, NM_001288616.1 [Q5W5X9-1]
XP_016878001.1, XM_017022512.1 [Q5W5X9-1]
XP_016878002.1, XM_017022513.1 [Q5W5X9-1]
XP_016878003.1, XM_017022514.1 [Q5W5X9-1]
XP_016878004.1, XM_017022515.1 [Q5W5X9-1]
XP_016878005.1, XM_017022516.1 [Q5W5X9-1]
XP_016878006.1, XM_017022517.1
XP_016878007.1, XM_017022518.1 [Q5W5X9-1]

UniGene gene-oriented nucleotide sequence clusters

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UniGenei
Hs.513195
Hs.621260
Hs.737076

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000262074; ENSP00000262074; ENSG00000103852 [Q5W5X9-3]
ENST00000394129; ENSP00000457901; ENSG00000103852 [Q5W5X9-2]
ENST00000394132; ENSP00000377690; ENSG00000103852 [Q5W5X9-1]
ENST00000394135; ENSP00000377692; ENSG00000103852 [Q5W5X9-1]
ENST00000459771; ENSP00000433162; ENSG00000103852 [Q5W5X9-3]
ENST00000558663; ENSP00000452923; ENSG00000103852 [Q5W5X9-1]

Database of genes from NCBI RefSeq genomes

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GeneIDi
64927

KEGG: Kyoto Encyclopedia of Genes and Genomes

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KEGGi
hsa:64927

UCSC genome browser

More...
UCSCi
uc002buy.5 human [Q5W5X9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF411456 mRNA Translation: AAQ03215.1
AK022634 mRNA Translation: BAB14144.1 Different initiation.
AK023230 mRNA Translation: BAB14480.1
AK222580 mRNA Translation: BAD96300.1
AK291690 mRNA Translation: BAF84379.1
BC015728 mRNA Translation: AAH15728.1
CCDSiCCDS10379.2 [Q5W5X9-1]
RefSeqiNP_001275544.1, NM_001288615.1 [Q5W5X9-1]
NP_001275545.1, NM_001288616.1 [Q5W5X9-1]
XP_016878001.1, XM_017022512.1 [Q5W5X9-1]
XP_016878002.1, XM_017022513.1 [Q5W5X9-1]
XP_016878003.1, XM_017022514.1 [Q5W5X9-1]
XP_016878004.1, XM_017022515.1 [Q5W5X9-1]
XP_016878005.1, XM_017022516.1 [Q5W5X9-1]
XP_016878006.1, XM_017022517.1
XP_016878007.1, XM_017022518.1 [Q5W5X9-1]
UniGeneiHs.513195
Hs.621260
Hs.737076

3D structure databases

ProteinModelPortaliQ5W5X9
SMRiQ5W5X9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122349, 22 interactors
IntActiQ5W5X9, 94 interactors
MINTiQ5W5X9

PTM databases

iPTMnetiQ5W5X9
PhosphoSitePlusiQ5W5X9

Polymorphism and mutation databases

DMDMi74708246

Proteomic databases

EPDiQ5W5X9
PaxDbiQ5W5X9
PeptideAtlasiQ5W5X9
PRIDEiQ5W5X9
ProteomicsDBi65810
65811 [Q5W5X9-2]
65812 [Q5W5X9-3]

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
64927
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000262074; ENSP00000262074; ENSG00000103852 [Q5W5X9-3]
ENST00000394129; ENSP00000457901; ENSG00000103852 [Q5W5X9-2]
ENST00000394132; ENSP00000377690; ENSG00000103852 [Q5W5X9-1]
ENST00000394135; ENSP00000377692; ENSG00000103852 [Q5W5X9-1]
ENST00000459771; ENSP00000433162; ENSG00000103852 [Q5W5X9-3]
ENST00000558663; ENSP00000452923; ENSG00000103852 [Q5W5X9-1]
GeneIDi64927
KEGGihsa:64927
UCSCiuc002buy.5 human [Q5W5X9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
64927
EuPathDBiHostDB:ENSG00000103852.12

GeneCards: human genes, protein and diseases

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GeneCardsi
TTC23
HGNCiHGNC:25730 TTC23
HPAiHPA039806
HPA040369
neXtProtiNX_Q5W5X9
OpenTargetsiENSG00000103852
PharmGKBiPA142670675

GenAtlas: human gene database

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GenAtlasi
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Phylogenomic databases

eggNOGiENOG410IJRU Eukaryota
ENOG410XVCY LUCA
GeneTreeiENSGT00530000063847
HOGENOMiHOG000154704
HOVERGENiHBG096816
InParanoidiQ5W5X9
OMAiPYNDNTD
OrthoDBiEOG091G08RQ
PhylomeDBiQ5W5X9
TreeFamiTF332604

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
TTC23 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

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GenomeRNAii
64927

Protein Ontology

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PROi
PR:Q5W5X9

Gene expression databases

BgeeiENSG00000103852 Expressed in 138 organ(s), highest expression level in lower esophagus
CleanExiHS_TTC23
ExpressionAtlasiQ5W5X9 baseline and differential
GenevisibleiQ5W5X9 HS

Family and domain databases

Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
SMARTiView protein in SMART
SM00028 TPR, 4 hits
SUPFAMiSSF48452 SSF48452, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTTC23_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5W5X9
Secondary accession number(s): A8K6M5
, Q53HK0, Q96BC9, Q9H8W9, Q9H9S7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: December 7, 2004
Last modified: November 7, 2018
This is version 117 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
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