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UniProtKB - Q5W5X9 (TTC23_HUMAN)

Entry version 121 (08 May 2019)
Sequence version 1 (07 Dec 2004)
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Protein

Tetratricopeptide repeat protein 23

Gene

TTC23

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tetratricopeptide repeat protein 23
Short name:
TPR repeat protein 23
Alternative name(s):
Cervical cancer proto-oncogene 8 protein
Short name:
HCC-8
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TTC23
ORF Names:HCC8
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 15

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:25730 TTC23

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5W5X9

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000103852

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA142670675

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		TTC23

Domain mapping of disease mutations (DMDM)

More...DMDMi		74708246

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002895481 – 447Tetratricopeptide repeat protein 23Add BLAST447

Proteomic databases

Encyclopedia of Proteome Dynamics

More...EPDi		Q5W5X9

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5W5X9

PeptideAtlas

More...PeptideAtlasi		Q5W5X9

PRoteomics IDEntifications database

More...PRIDEi		Q5W5X9

ProteomicsDB human proteome resource

More...ProteomicsDBi		65810
65811 [Q5W5X9-2]
65812 [Q5W5X9-3]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5W5X9

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5W5X9

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000103852 Expressed in 138 organ(s), highest expression level in lower esophagus

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5W5X9 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5W5X9 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA039806
HPA040369

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction_section%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		122349, 22 interactors

Protein interaction database and analysis system

More...IntActi		Q5W5X9, 94 interactors

Molecular INTeraction database

More...MINTi		Q5W5X9

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000377690

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5W5X9

Database of comparative protein structure models

More...ModBasei		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati45 – 78TPR 1Add BLAST34
Repeati137 – 170TPR 2Add BLAST34
Repeati186 – 219TPR 3Add BLAST34
Repeati356 – 389TPR 4Add BLAST34

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Repeat, TPR repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IJRU Eukaryota
ENOG410XVCY LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00530000063847

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		HOG000154704

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5W5X9

Identification of Orthologs from Complete Genome Data

More...OMAi		VPPYNDN

Database of Orthologous Groups

More...OrthoDBi		1014824at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5W5X9

TreeFam database of animal gene trees

More...TreeFami		TF332604

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.25.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00028 TPR, 4 hits

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF48452 SSF48452, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 3 described isoforms and 8 potential isoforms that are computationally mapped.Show allAlign All

Isoform 1 (identifier: Q5W5X9-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MQESQETHIS NHLDEVVAAV SITHRKKFQN KLLQTALFQP PREKLHLCEE 
        60         70         80         90        100
KAKSYSNSHE YKQAVHELVR CVALTRICYG DSHWKLAEAH VNLAQGYLQL 
       110        120        130        140        150
KGLSLQAKQH AEKARQILAN SIVPPYSENT DVFKFSIELF HTMGRALLSL 
       160        170        180        190        200
QKFKEAAENL TKAERLSKEL LQCGRIIKEE WIEIEARIRL SFAQVYQGQK 
       210        220        230        240        250
KSKEALSHYQ AALEYVEISK GETSRECVPI LRELAGVEQA LGLHDVSINH 
       260        270        280        290        300
FLQAHLIILS RSPSQVEAAD SAHIVAHAAV ASGRHEHHDV AEQYFQESMA 
       310        320        330        340        350
HLKDSEGMGR TKFLSIQDEF CHFLQMTGQK ERATSILRES LEAKVEAFGD 
       360        370        380        390        400
FSPEVAETYR LLGGADLAQG NHSGARKKLK KCLQIQTLLY GPQDKRTLAT 
       410        420        430        440 
QQAMGMLSTA PKVASKPRQA SKAKVAFCTS IPQDTLLGKA RPGTTAD
Length:447
Mass (Da):50,009
Last modified:December 7, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i7548138692B33E57
GO
Isoform 2 (identifier: Q5W5X9-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     382-447: CLQIQTLLYG...GKARPGTTAD → VKLEPVLTRD

Show »
Length:391
Mass (Da):44,174
Checksum:i4D38FFBA005B3041
GO
Isoform 3 (identifier: Q5W5X9-3) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     382-447: CLQIQTLLYG...GKARPGTTAD → GDLSFLLSATLP

Note: May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay. No experimental confirmation available.
Show »
Length:393
Mass (Da):44,238
Checksum:iA7C4AAC73EAA15A5
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 8 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H7BZG4H7BZG4_HUMAN
Tetratricopeptide repeat protein 23
TTC23
263Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YNV8H0YNV8_HUMAN
Tetratricopeptide repeat protein 23
TTC23
157Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YNH7H0YNH7_HUMAN
Tetratricopeptide repeat protein 23
TTC23
151Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YMN1H0YMN1_HUMAN
Tetratricopeptide repeat protein 23
TTC23
56Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YKN9H0YKN9_HUMAN
Tetratricopeptide repeat protein 23
TTC23
53Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YM10H0YM10_HUMAN
Tetratricopeptide repeat protein 23
TTC23
115Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YN45H0YN45_HUMAN
Tetratricopeptide repeat protein 23
TTC23
83Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
H0YET0H0YET0_HUMAN
Tetratricopeptide repeat protein 23
TTC23
73Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB14144 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti374G → E in BAD96300 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_026017382 – 447CLQIQ…GTTAD → VKLEPVLTRD in isoform 2. 1 PublicationAdd BLAST66
Alternative sequenceiVSP_026018382 – 447CLQIQ…GTTAD → GDLSFLLSATLP in isoform 3. 1 PublicationAdd BLAST66

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AF411456 mRNA Translation: AAQ03215.1
AK022634 mRNA Translation: BAB14144.1 Different initiation.
AK023230 mRNA Translation: BAB14480.1
AK222580 mRNA Translation: BAD96300.1
AK291690 mRNA Translation: BAF84379.1
BC015728 mRNA Translation: AAH15728.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS10379.2 [Q5W5X9-1]

NCBI Reference Sequences

More...RefSeqi		NP_001275544.1, NM_001288615.1 [Q5W5X9-1]
NP_001275545.1, NM_001288616.1 [Q5W5X9-1]
XP_016878001.1, XM_017022512.1 [Q5W5X9-1]
XP_016878002.1, XM_017022513.1 [Q5W5X9-1]
XP_016878003.1, XM_017022514.1 [Q5W5X9-1]
XP_016878004.1, XM_017022515.1 [Q5W5X9-1]
XP_016878005.1, XM_017022516.1 [Q5W5X9-1]
XP_016878006.1, XM_017022517.1
XP_016878007.1, XM_017022518.1 [Q5W5X9-1]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000262074; ENSP00000262074; ENSG00000103852 [Q5W5X9-3]
ENST00000394129; ENSP00000457901; ENSG00000103852 [Q5W5X9-2]
ENST00000394132; ENSP00000377690; ENSG00000103852 [Q5W5X9-1]
ENST00000394135; ENSP00000377692; ENSG00000103852 [Q5W5X9-1]
ENST00000459771; ENSP00000433162; ENSG00000103852 [Q5W5X9-3]
ENST00000558663; ENSP00000452923; ENSG00000103852 [Q5W5X9-1]

Database of genes from NCBI RefSeq genomes

More...GeneIDi		64927

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:64927

UCSC genome browser

More...UCSCi		uc002buy.5 human [Q5W5X9-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF411456 mRNA Translation: AAQ03215.1
AK022634 mRNA Translation: BAB14144.1 Different initiation.
AK023230 mRNA Translation: BAB14480.1
AK222580 mRNA Translation: BAD96300.1
AK291690 mRNA Translation: BAF84379.1
BC015728 mRNA Translation: AAH15728.1
CCDSiCCDS10379.2 [Q5W5X9-1]
RefSeqiNP_001275544.1, NM_001288615.1 [Q5W5X9-1]
NP_001275545.1, NM_001288616.1 [Q5W5X9-1]
XP_016878001.1, XM_017022512.1 [Q5W5X9-1]
XP_016878002.1, XM_017022513.1 [Q5W5X9-1]
XP_016878003.1, XM_017022514.1 [Q5W5X9-1]
XP_016878004.1, XM_017022515.1 [Q5W5X9-1]
XP_016878005.1, XM_017022516.1 [Q5W5X9-1]
XP_016878006.1, XM_017022517.1
XP_016878007.1, XM_017022518.1 [Q5W5X9-1]

3D structure databases

SMRiQ5W5X9
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi122349, 22 interactors
IntActiQ5W5X9, 94 interactors
MINTiQ5W5X9
STRINGi9606.ENSP00000377690

PTM databases

iPTMnetiQ5W5X9
PhosphoSitePlusiQ5W5X9

Polymorphism and mutation databases

BioMutaiTTC23
DMDMi74708246

Proteomic databases

EPDiQ5W5X9
PaxDbiQ5W5X9
PeptideAtlasiQ5W5X9
PRIDEiQ5W5X9
ProteomicsDBi65810
65811 [Q5W5X9-2]
65812 [Q5W5X9-3]

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		64927
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000262074; ENSP00000262074; ENSG00000103852 [Q5W5X9-3]
ENST00000394129; ENSP00000457901; ENSG00000103852 [Q5W5X9-2]
ENST00000394132; ENSP00000377690; ENSG00000103852 [Q5W5X9-1]
ENST00000394135; ENSP00000377692; ENSG00000103852 [Q5W5X9-1]
ENST00000459771; ENSP00000433162; ENSG00000103852 [Q5W5X9-3]
ENST00000558663; ENSP00000452923; ENSG00000103852 [Q5W5X9-1]
GeneIDi64927
KEGGihsa:64927
UCSCiuc002buy.5 human [Q5W5X9-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		64927

GeneCards: human genes, protein and diseases

More...GeneCardsi		TTC23
HGNCiHGNC:25730 TTC23
HPAiHPA039806
HPA040369
neXtProtiNX_Q5W5X9
OpenTargetsiENSG00000103852
PharmGKBiPA142670675

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IJRU Eukaryota
ENOG410XVCY LUCA
GeneTreeiENSGT00530000063847
HOGENOMiHOG000154704
InParanoidiQ5W5X9
OMAiVPPYNDN
OrthoDBi1014824at2759
PhylomeDBiQ5W5X9
TreeFamiTF332604

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		TTC23 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		64927

Protein Ontology

More...PROi		PR:Q5W5X9

Gene expression databases

BgeeiENSG00000103852 Expressed in 138 organ(s), highest expression level in lower esophagus
ExpressionAtlasiQ5W5X9 baseline and differential
GenevisibleiQ5W5X9 HS

Family and domain databases

Gene3Di1.25.40.10, 2 hits
InterProiView protein in InterPro
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
SMARTiView protein in SMART
SM00028 TPR, 4 hits
SUPFAMiSSF48452 SSF48452, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTTC23_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5W5X9
Secondary accession number(s): A8K6M5
, Q53HK0, Q96BC9, Q9H8W9, Q9H9S7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 29, 2007
Last sequence update: December 7, 2004
Last modified: May 8, 2019
This is version 121 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 15
    Human chromosome 15: entries, gene names and cross-references to MIM
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