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Protein

Putative uncharacterized protein C10orf113

Gene

C10orf113

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Encoded in intron of the NEBL gene.Curated

Names & Taxonomyi

Protein namesi
Recommended name:
Putative uncharacterized protein C10orf113
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000204683.10
HGNCiHGNC:31447 C10orf113
neXtProtiNX_Q5VZT2

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000204683
PharmGKBiPA134950749

Polymorphism and mutation databases

BioMutaiC10orf113

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002540391 – 155Putative uncharacterized protein C10orf113Add BLAST155

Proteomic databases

PaxDbiQ5VZT2
PeptideAtlasiQ5VZT2
PRIDEiQ5VZT2
ProteomicsDBi65723

PTM databases

iPTMnetiQ5VZT2
PhosphoSitePlusiQ5VZT2

Expressioni

Gene expression databases

BgeeiENSG00000204683
CleanExiHS_C10orf113

Organism-specific databases

HPAiHPA037013

Structurei

3D structure databases

SMRiQ5VZT2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiENOG410J2MX Eukaryota
ENOG41115PV LUCA
GeneTreeiENSGT00410000028701
HOGENOMiHOG000111707
InParanoidiQ5VZT2
OMAiPNELFRE
OrthoDBiEOG091G1335
PhylomeDBiQ5VZT2
TreeFamiTF353304

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q5VZT2-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAKSERRIYS MESMAPEISE DIGCPLAYMR ESVCALLINQ SFFSCVAEMY
60 70 80 90 100
IPDMNRPGKA ERRAEKGLRP PRKLVGETRR LQSWPTLARW LRRVSFSLYK
110 120 130 140 150
PPIQAAPEPD PGNWAKSPRL SLGPEGITKG KHGFKFQGIK EKFNVSKKVL

KMTFL
Length:155
Mass (Da):17,689
Last modified:June 28, 2011 - v2
Checksum:i71E5D38A3FA07109
GO
Isoform 2 (identifier: Q5VZT2-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     57-79: PGKAERRAEKGLRPPRKLVGETR → LEERTAALYPIGLVRQNGEPRRA
     80-155: Missing.

Note: No experimental confirmation available.
Show »
Length:79
Mass (Da):9,021
Checksum:i4932F1B405B985AF
GO

Sequence cautioni

The sequence AAI40745 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated
The sequence CAH70812 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural variantiVAR_05085872R → G. Corresponds to variant dbSNP:rs11591355Ensembl.1
Natural variantiVAR_028801110D → H1 PublicationCorresponds to variant dbSNP:rs625223Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_04497457 – 79PGKAE…VGETR → LEERTAALYPIGLVRQNGEP RRA in isoform 2. 1 PublicationAdd BLAST23
Alternative sequenceiVSP_04497580 – 155Missing in isoform 2. 1 PublicationAdd BLAST76

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL158160 Genomic DNA Translation: CAH70812.1 Different initiation.
BC140744 mRNA Translation: AAI40745.1 Different initiation.
BC144447 mRNA No translation available.
CCDSiCCDS31162.2 [Q5VZT2-1]
CCDS53496.1 [Q5VZT2-2]
RefSeqiNP_001010896.2, NM_001010896.2 [Q5VZT2-1]
NP_001170954.1, NM_001177483.1 [Q5VZT2-2]
UniGeneiHs.664110

Genome annotation databases

EnsembliENST00000529198; ENSP00000434089; ENSG00000204683 [Q5VZT2-2]
ENST00000534331; ENSP00000433646; ENSG00000204683 [Q5VZT2-1]
GeneIDi387638
KEGGihsa:387638
UCSCiuc001iqm.3 human [Q5VZT2-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCJ113_HUMAN
AccessioniPrimary (citable) accession number: Q5VZT2
Secondary accession number(s): B9EIM9, E9PRX7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 28, 2011
Last modified: June 20, 2018
This is version 90 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations

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