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Protein
Submitted name:

Programmed cell death protein 4

Gene

PDCD4

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Submitted name:
Programmed cell death protein 4Imported
Gene namesi
Name:PDCD4Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiHostDB:ENSG00000150593.15
HGNCiHGNC:8763 PDCD4

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000150593

PTM / Processingi

Proteomic databases

EPDiQ5VZS7
MaxQBiQ5VZS7
PeptideAtlasiQ5VZS7
PRIDEiQ5VZS7

Expressioni

Gene expression databases

BgeeiENSG00000150593 Expressed in 231 organ(s), highest expression level in body of pancreas
ExpressionAtlasiQ5VZS7 baseline and differential

Structurei

3D structure databases

ProteinModelPortaliQ5VZS7
SMRiQ5VZS7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini149 – 231MIInterPro annotationAdd BLAST83

Phylogenomic databases

GeneTreeiENSGT00390000015948
HOGENOMiHOG000261612
HOVERGENiHBG052841

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR003891 Initiation_fac_eIF4g_MI
IPR016021 MIF4-like_sf
IPR039778 PDCD4
PANTHERiPTHR12626 PTHR12626, 1 hit
PfamiView protein in Pfam
PF02847 MA3, 1 hit
SMARTiView protein in SMART
SM00544 MA3, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51366 MI, 1 hit

Sequence (1+)i

Sequence statusi: Fragment.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5VZS7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDVENEQILN VNPAENAGTE EIKNEINGNW ISASSINEAR INAKAKRRLR
60 70 80 90 100
KNSSRDSGRG DSVSDSGSDA LRSGLTVPTS PKGRLLDRRS RSGKGRGLPK
110 120 130 140 150
KGGAGGKGVW GTPGQVYDVE EVDVKDPNYD DDQENCVYET VVLPLDERAF
160 170 180 190 200
EKTLTPIIQE YFEHGDTNEV AEMLRDLNLG EMKSGVPVLA VSLALEGKAS
210 220 230
HREMTSKLLS DLCGTVMSTT DVEKSFDKLL K
Length:231
Mass (Da):25,197
Last modified:December 7, 2004 - v1
Checksum:i29B27A18BB70CF43
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q53EL6PDCD4_HUMAN
Programmed cell death protein 4
PDCD4 H731
469Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei231Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136368 Genomic DNA No translation available.
AL158163 Genomic DNA No translation available.

Genome annotation databases

EnsembliENST00000444997; ENSP00000394668; ENSG00000150593
UCSCiuc057vze.1 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL136368 Genomic DNA No translation available.
AL158163 Genomic DNA No translation available.

3D structure databases

ProteinModelPortaliQ5VZS7
SMRiQ5VZS7
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

EPDiQ5VZS7
MaxQBiQ5VZS7
PeptideAtlasiQ5VZS7
PRIDEiQ5VZS7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000444997; ENSP00000394668; ENSG00000150593
UCSCiuc057vze.1 human

Organism-specific databases

EuPathDBiHostDB:ENSG00000150593.15
HGNCiHGNC:8763 PDCD4
OpenTargetsiENSG00000150593
GenAtlasiSearch...

Phylogenomic databases

GeneTreeiENSGT00390000015948
HOGENOMiHOG000261612
HOVERGENiHBG052841

Miscellaneous databases

ChiTaRSiPDCD4 human

Gene expression databases

BgeeiENSG00000150593 Expressed in 231 organ(s), highest expression level in body of pancreas
ExpressionAtlasiQ5VZS7 baseline and differential

Family and domain databases

Gene3Di1.25.40.180, 1 hit
InterProiView protein in InterPro
IPR016024 ARM-type_fold
IPR003891 Initiation_fac_eIF4g_MI
IPR016021 MIF4-like_sf
IPR039778 PDCD4
PANTHERiPTHR12626 PTHR12626, 1 hit
PfamiView protein in Pfam
PF02847 MA3, 1 hit
SMARTiView protein in SMART
SM00544 MA3, 1 hit
SUPFAMiSSF48371 SSF48371, 1 hit
PROSITEiView protein in PROSITE
PS51366 MI, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiQ5VZS7_HUMAN
AccessioniPrimary (citable) accession number: Q5VZS7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 7, 2004
Last sequence update: December 7, 2004
Last modified: November 7, 2018
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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