Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

MORN repeat-containing protein 5

Gene

MORN5

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
MORN repeat-containing protein 5
Gene namesi
Name:MORN5
Synonyms:C9orf113, C9orf18
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 9

Organism-specific databases

EuPathDBiHostDB:ENSG00000185681.12
HGNCiHGNC:17841 MORN5
neXtProtiNX_Q5VZ52

Pathology & Biotechi

Organism-specific databases

DisGeNETi254956
OpenTargetsiENSG00000185681
PharmGKBiPA25975

Polymorphism and mutation databases

BioMutaiMORN5
DMDMi74747757

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002928401 – 161MORN repeat-containing protein 5Add BLAST161

Proteomic databases

PaxDbiQ5VZ52
PeptideAtlasiQ5VZ52
PRIDEiQ5VZ52
ProteomicsDBi65672

PTM databases

iPTMnetiQ5VZ52
PhosphoSitePlusiQ5VZ52

Expressioni

Gene expression databases

BgeeiENSG00000185681 Expressed in 102 organ(s), highest expression level in bronchial epithelial cell
CleanExiHS_MORN5
ExpressionAtlasiQ5VZ52 baseline and differential
GenevisibleiQ5VZ52 HS

Interactioni

Protein-protein interaction databases

BioGridi129063, 3 interactors
IntActiQ5VZ52, 10 interactors
STRINGi9606.ENSP00000362869

Structurei

3D structure databases

ProteinModelPortaliQ5VZ52
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati8 – 30MORN 1Add BLAST23
Repeati31 – 53MORN 2Add BLAST23
Repeati54 – 75MORN 3Add BLAST22

Keywords - Domaini

Repeat

Phylogenomic databases

eggNOGiKOG0231 Eukaryota
COG4642 LUCA
GeneTreeiENSGT00390000018089
HOGENOMiHOG000007133
HOVERGENiHBG059322
InParanoidiQ5VZ52
OMAiWIVRTCR
OrthoDBiEOG091G0C1Z
PhylomeDBiQ5VZ52
TreeFamiTF327409

Family and domain databases

InterProiView protein in InterPro
IPR003409 MORN
PfamiView protein in Pfam
PF02493 MORN, 3 hits
SMARTiView protein in SMART
SM00698 MORN, 2 hits

Sequences (2+)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

This entry has 2 described isoforms and 2 potential isoforms that are computationally mapped.iShow all

Isoform 1 (identifier: Q5VZ52-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MEYTGSKYIG EYVDGRMEGK AKYILPTETI YVGEMKDGMF HGEGTLYFPS
60 70 80 90 100
GSQYDAIWEN GLAIKGTYTF SDGLHYDEKN WHYCDGYDRR FYTEILNGLK
110 120 130 140 150
PAGMAQLTNM DPPRKIPKGY YDCGDGFYNP VTRVVKDYRN RFLRNADDDE
160
HEWITRTCRK G
Length:161
Mass (Da):18,731
Last modified:December 7, 2004 - v1
Checksum:iC0DA34ED1D015866
GO
Isoform 2 (identifier: Q5VZ52-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     147-161: DDDEHEWITRTCRKG → GRFLPTLQHVFSSPTYEYVHLYVQMYAHT

Note: No experimental confirmation available.
Show »
Length:175
Mass (Da):20,356
Checksum:i1AE8178BAD0B6C65
GO

Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
A0A0A0MTF6A0A0A0MTF6_HUMAN
MORN repeat-containing protein 5
MORN5
96Annotation score:
Q5T7S4Q5T7S4_HUMAN
MORN repeat-containing protein 5
MORN5
110Annotation score:

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti45T → A in BAC87653 (PubMed:14702039).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_055496147 – 161DDDEH…TCRKG → GRFLPTLQHVFSSPTYEYVH LYVQMYAHT in isoform 2. 1 PublicationAdd BLAST15

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK128877 mRNA Translation: BAC87653.1
AK302081 mRNA Translation: BAH13621.1
AL162423 Genomic DNA No translation available.
AL162424 Genomic DNA No translation available.
CH471090 Genomic DNA Translation: EAW87512.1
BC133690 mRNA Translation: AAI33691.1
CCDSiCCDS6836.1 [Q5VZ52-1]
RefSeqiNP_001273757.1, NM_001286828.1
NP_940871.2, NM_198469.3 [Q5VZ52-1]
XP_005251934.1, XM_005251877.4 [Q5VZ52-2]
UniGeneiHs.71428

Genome annotation databases

EnsembliENST00000373764; ENSP00000362869; ENSG00000185681 [Q5VZ52-1]
GeneIDi254956
KEGGihsa:254956
UCSCiuc004blw.4 human [Q5VZ52-1]

Keywords - Coding sequence diversityi

Alternative splicing

Similar proteinsi

Entry informationi

Entry nameiMORN5_HUMAN
AccessioniPrimary (citable) accession number: Q5VZ52
Secondary accession number(s): B7Z7I5, Q6ZQN1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 26, 2007
Last sequence update: December 7, 2004
Last modified: September 12, 2018
This is version 96 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again