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Entry version 110 (08 May 2019)
Sequence version 3 (16 Jun 2009)
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Protein

Tudor domain-containing protein 10

Gene

TDRD10

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRNA-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Tudor domain-containing protein 10
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:TDRD10
ORF Names:UNQ9380/PRO34205
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:25316 TDRD10

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5VZ19

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

DisGeNET

More...
DisGeNETi
126668

Open Targets

More...
OpenTargetsi
ENSG00000163239

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA142670823

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
TDRD10

Domain mapping of disease mutations (DMDM)

More...
DMDMi
239938838

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00002707541 – 366Tudor domain-containing protein 10Add BLAST366

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5VZ19

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5VZ19

PeptideAtlas

More...
PeptideAtlasi
Q5VZ19

PRoteomics IDEntifications database

More...
PRIDEi
Q5VZ19

ProteomicsDB human proteome resource

More...
ProteomicsDBi
65664
65665 [Q5VZ19-2]

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5VZ19

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5VZ19

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000163239 Expressed in 140 organ(s), highest expression level in right testis

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5VZ19 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA054327

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
126008, 2 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000357465

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5VZ19

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini34 – 107RRMPROSITE-ProRule annotationAdd BLAST74
Domaini210 – 317TudorAdd BLAST108

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili216 – 237Sequence analysisAdd BLAST22

Keywords - Domaini

Coiled coil

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKPU Eukaryota
ENOG4111FQ7 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00390000006620

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5VZ19

Identification of Orthologs from Complete Genome Data

More...
OMAi
DFWAIPP

Database of Orthologous Groups

More...
OrthoDBi
1361661at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5VZ19

TreeFam database of animal gene trees

More...
TreeFami
TF343710

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.70.330, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR002999 Tudor

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00076 RRM_1, 1 hit
PF00567 TUDOR, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00360 RRM, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54928 SSF54928, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50102 RRM, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (2)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 2 <p>This subsection of the ‘Sequence’ section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: Q5VZ19-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MSWNISHPQL SDKLFGKNGV LEEQKSPGFK KRETEVYVGN LPLDISKEEI
60 70 80 90 100
LYLLKDFNPL DVHKIQNGCK CFAFVDLGSM QKVTLAIQEL NGKLFHKRKL
110 120 130 140 150
FVNTSKRPPK RTPDMIQQPR APLVLEKASG EGFGKTAAII QLAPKAPVDL
160 170 180 190 200
CETEKLRAAF FAVPLEMRGS FLVLLLRECF RDLSWLALIH SVRGEAGLLV
210 220 230 240 250
TSIVPKTPFF WAMHVTEALH QNMQALFSTL AQAEEQQPYL EGSTVMRGTR
260 270 280 290 300
CLAEYHLGDY GHAWNRCWVL DRVDTWAVVM FIDFGQLATI PVQSLRSLDS
310 320 330 340 350
DDFWTIPPLT QPFMLEKDIL SSYEVVHRIL KGKITGALNS AVTAPASNLA
360
VVPPLLPLGC LQQAAA
Length:366
Mass (Da):40,941
Last modified:June 16, 2009 - v3
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0CA48444B9FF6F49
GO
Isoform 2 (identifier: Q5VZ19-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     342-366: VTAPASNLAVVPPLLPLGCLQQAAA → LHILKFEESK

Show »
Length:351
Mass (Da):39,769
Checksum:iEB931A94349AFB8B
GO

<p>This subsection of the ‘Sequence’ section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence AAH44864 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI00896 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI00897 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI00898 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAI00899 differs from that shown. Reason: Erroneous initiation.Curated
The sequence AAQ88562 differs from that shown. Reason: Erroneous initiation.Curated
The sequence CAD28538 differs from that shown. Reason: Frameshift at positions 93 and 242.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti93K → N in CAD28538 (PubMed:17974005).Curated1
Sequence conflicti297S → Q in CAD28538 (PubMed:17974005).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_029817181R → Q. Corresponds to variant dbSNP:rs12750774Ensembl.1
Natural variantiVAR_029818215V → I3 PublicationsCorresponds to variant dbSNP:rs3811448Ensembl.1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_022216342 – 366VTAPA…QQAAA → LHILKFEESK in isoform 2. 1 PublicationAdd BLAST25

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK302144 mRNA Translation: BAG63516.1
AL162591 Genomic DNA No translation available.
AL592078 Genomic DNA No translation available.
BC044864 mRNA Translation: AAH44864.1 Different initiation.
BC100895 mRNA Translation: AAI00896.1 Different initiation.
BC100896 mRNA Translation: AAI00897.1 Different initiation.
BC100897 mRNA Translation: AAI00898.1 Different initiation.
BC100898 mRNA Translation: AAI00899.1 Different initiation.
AL713777 mRNA Translation: CAD28538.1 Frameshift.
AY358195 mRNA Translation: AAQ88562.1 Different initiation.

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS30878.2 [Q5VZ19-2]
CCDS41406.1 [Q5VZ19-1]

NCBI Reference Sequences

More...
RefSeqi
NP_001091945.1, NM_001098475.1 [Q5VZ19-1]
NP_872305.3, NM_182499.3 [Q5VZ19-2]
XP_006711219.1, XM_006711156.2
XP_011507462.1, XM_011509160.2
XP_011507463.1, XM_011509161.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000368480; ENSP00000357465; ENSG00000163239 [Q5VZ19-1]
ENST00000368482; ENSP00000357467; ENSG00000163239 [Q5VZ19-2]

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
126668

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:126668

UCSC genome browser

More...
UCSCi
uc001ffd.3 human [Q5VZ19-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK302144 mRNA Translation: BAG63516.1
AL162591 Genomic DNA No translation available.
AL592078 Genomic DNA No translation available.
BC044864 mRNA Translation: AAH44864.1 Different initiation.
BC100895 mRNA Translation: AAI00896.1 Different initiation.
BC100896 mRNA Translation: AAI00897.1 Different initiation.
BC100897 mRNA Translation: AAI00898.1 Different initiation.
BC100898 mRNA Translation: AAI00899.1 Different initiation.
AL713777 mRNA Translation: CAD28538.1 Frameshift.
AY358195 mRNA Translation: AAQ88562.1 Different initiation.
CCDSiCCDS30878.2 [Q5VZ19-2]
CCDS41406.1 [Q5VZ19-1]
RefSeqiNP_001091945.1, NM_001098475.1 [Q5VZ19-1]
NP_872305.3, NM_182499.3 [Q5VZ19-2]
XP_006711219.1, XM_006711156.2
XP_011507462.1, XM_011509160.2
XP_011507463.1, XM_011509161.1

3D structure databases

SMRiQ5VZ19
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi126008, 2 interactors
STRINGi9606.ENSP00000357465

PTM databases

iPTMnetiQ5VZ19
PhosphoSitePlusiQ5VZ19

Polymorphism and mutation databases

BioMutaiTDRD10
DMDMi239938838

Proteomic databases

EPDiQ5VZ19
PaxDbiQ5VZ19
PeptideAtlasiQ5VZ19
PRIDEiQ5VZ19
ProteomicsDBi65664
65665 [Q5VZ19-2]

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000368480; ENSP00000357465; ENSG00000163239 [Q5VZ19-1]
ENST00000368482; ENSP00000357467; ENSG00000163239 [Q5VZ19-2]
GeneIDi126668
KEGGihsa:126668
UCSCiuc001ffd.3 human [Q5VZ19-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
126668
DisGeNETi126668

GeneCards: human genes, protein and diseases

More...
GeneCardsi
TDRD10

H-Invitational Database, human transcriptome db

More...
H-InvDBi
HIX0001105
HGNCiHGNC:25316 TDRD10
HPAiHPA054327
neXtProtiNX_Q5VZ19
OpenTargetsiENSG00000163239
PharmGKBiPA142670823

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IKPU Eukaryota
ENOG4111FQ7 LUCA
GeneTreeiENSGT00390000006620
InParanoidiQ5VZ19
OMAiDFWAIPP
OrthoDBi1361661at2759
PhylomeDBiQ5VZ19
TreeFamiTF343710

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
TDRD10 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
126668

Protein Ontology

More...
PROi
PR:Q5VZ19

Gene expression databases

BgeeiENSG00000163239 Expressed in 140 organ(s), highest expression level in right testis
GenevisibleiQ5VZ19 HS

Family and domain databases

Gene3Di3.30.70.330, 1 hit
InterProiView protein in InterPro
IPR012677 Nucleotide-bd_a/b_plait_sf
IPR035979 RBD_domain_sf
IPR000504 RRM_dom
IPR002999 Tudor
PfamiView protein in Pfam
PF00076 RRM_1, 1 hit
PF00567 TUDOR, 1 hit
SMARTiView protein in SMART
SM00360 RRM, 1 hit
SUPFAMiSSF54928 SSF54928, 1 hit
PROSITEiView protein in PROSITE
PS50102 RRM, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiTDR10_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5VZ19
Secondary accession number(s): A4FU09
, B0QZ53, B4DXV4, Q3ZCP1, Q3ZCS7, Q5SXY7, Q6UXV2, Q8TCN3
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 9, 2007
Last sequence update: June 16, 2009
Last modified: May 8, 2019
This is version 110 of the entry and version 3 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 1
    Human chromosome 1: entries, gene names and cross-references to MIM
  2. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  3. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
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