UniProtKB - Q5VWG9 (TAF3_HUMAN)
Transcription initiation factor TFIID subunit 3
TAF3
Functioni
The TFIID basal transcription factor complex plays a major role in the initiation of RNA polymerase II (Pol II)-dependent transcription (PubMed:33795473).
TFIID recognizes and binds promoters with or without a TATA box via its subunit TBP, a TATA-box-binding protein, and promotes assembly of the pre-initiation complex (PIC) (PubMed:33795473).
The TFIID complex consists of TBP and TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473).
The TFIID complex structure can be divided into 3 modules TFIID-A, TFIID-B, and TFIID-C (PubMed:33795473).
TAF3 forms the TFIID-A module together with TAF5 and TBP (PubMed:33795473).
Required in complex with TBPL2 for the differentiation of myoblasts into myocytes (PubMed:11438666).
The TAF3-TBPL2 complex replaces TFIID at specific promoters at an early stage in the differentiation process (PubMed:11438666).
2 PublicationsSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 868 | Zinc 1Combined sources | 1 | |
Metal bindingi | 871 | Zinc 1Combined sources | 1 | |
Metal bindingi | 883 | Zinc 2Combined sources | 1 | |
Metal bindingi | 886 | Zinc 2Combined sources | 1 | |
Metal bindingi | 891 | Zinc 1; via pros nitrogenCombined sources | 1 | |
Metal bindingi | 894 | Zinc 1Combined sources | 1 | |
Metal bindingi | 909 | Zinc 2Combined sources | 1 | |
Metal bindingi | 912 | Zinc 2Combined sources | 1 |
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 865 – 915 | PHD-typePROSITE-ProRule annotationAdd BLAST | 51 |
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
- p53 binding Source: Ensembl
- protein heterodimerization activity Source: InterPro
- RNA polymerase II general transcription initiation factor activity Source: ARUK-UCL
- transcription regulator inhibitor activity Source: Ensembl
GO - Biological processi
- maintenance of protein location in nucleus Source: HGNC-UCL
- mRNA transcription by RNA polymerase II Source: ComplexPortal
- negative regulation of DNA-binding transcription factor activity Source: BHF-UCL
- negative regulation of transcription by RNA polymerase II Source: BHF-UCL
- positive regulation of transcription initiation from RNA polymerase II promoter Source: ComplexPortal
- protein phosphorylation Source: ComplexPortal
- RNA polymerase II preinitiation complex assembly Source: ComplexPortal
Keywordsi
Biological process | Transcription, Transcription regulation |
Ligand | Metal-binding, Zinc |
Enzyme and pathway databases
PathwayCommonsi | Q5VWG9 |
Reactomei | R-HSA-167161, HIV Transcription Initiation R-HSA-167162, RNA Polymerase II HIV Promoter Escape R-HSA-167172, Transcription of the HIV genome R-HSA-674695, RNA Polymerase II Pre-transcription Events R-HSA-6804756, Regulation of TP53 Activity through Phosphorylation R-HSA-73776, RNA Polymerase II Promoter Escape R-HSA-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-75953, RNA Polymerase II Transcription Initiation R-HSA-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance |
SignaLinki | Q5VWG9 |
SIGNORi | Q5VWG9 |
Names & Taxonomyi
Protein namesi | Recommended name: Transcription initiation factor TFIID subunit 3Alternative name(s): 140 kDa TATA box-binding protein-associated factor TBP-associated factor 3 Transcription initiation factor TFIID 140 kDa subunit Short name: TAF(II)140 Short name: TAF140 Short name: TAFII-140 Short name: TAFII140 |
Gene namesi | Name:TAF3 |
Organismi | Homo sapiens (Human) |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:17303, TAF3 |
MIMi | 606576, gene |
neXtProti | NX_Q5VWG9 |
VEuPathDBi | HostDB:ENSG00000165632 |
Subcellular locationi
Nucleus
- Nucleus 1 Publication
Nucleus
- nuclear membrane Source: HPA
- nucleoplasm Source: HPA
- nucleus Source: HGNC-UCL
- transcription factor TFIID complex Source: UniProtKB
Keywords - Cellular componenti
NucleusPathology & Biotechi
Mutagenesis
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Mutagenesisi | 23 | W → R: Loss of interaction with TAF10. 1 Publication | 1 |
Organism-specific databases
DisGeNETi | 83860 |
OpenTargetsi | ENSG00000165632 |
PharmGKBi | PA38222 |
Miscellaneous databases
Pharosi | Q5VWG9, Tbio |
Chemistry databases
ChEMBLi | CHEMBL4523329 |
Genetic variation databases
BioMutai | TAF3 |
DMDMi | 74747393 |
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000245528 | 1 – 929 | Transcription initiation factor TFIID subunit 3Add BLAST | 929 |
Amino acid modifications
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Modified residuei | 183 | PhosphoserineCombined sources | 1 | |
Modified residuei | 199 | PhosphoserineCombined sources | 1 | |
Modified residuei | 229 | PhosphoserineCombined sources | 1 | |
Modified residuei | 243 | PhosphoserineCombined sources | 1 | |
Modified residuei | 266 | N6-acetyllysineCombined sources | 1 | |
Modified residuei | 291 | PhosphoserineCombined sources | 1 | |
Modified residuei | 297 | PhosphoserineCombined sources | 1 | |
Modified residuei | 301 | PhosphoserineCombined sources | 1 | |
Modified residuei | 501 | PhosphothreonineCombined sources | 1 | |
Cross-linki | 581 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 667 | PhosphoserineCombined sources | 1 | |
Cross-linki | 746 | Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)Combined sources | ||
Modified residuei | 755 | PhosphoserineCombined sources | 1 | |
Modified residuei | 776 | N6-acetyllysineCombined sources | 1 |
Keywords - PTMi
Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugationProteomic databases
EPDi | Q5VWG9 |
jPOSTi | Q5VWG9 |
MassIVEi | Q5VWG9 |
MaxQBi | Q5VWG9 |
PaxDbi | Q5VWG9 |
PeptideAtlasi | Q5VWG9 |
PRIDEi | Q5VWG9 |
ProteomicsDBi | 65526 |
PTM databases
iPTMneti | Q5VWG9 |
MetOSitei | Q5VWG9 |
PhosphoSitePlusi | Q5VWG9 |
Expressioni
Gene expression databases
Bgeei | ENSG00000165632, Expressed in tendon of biceps brachii and 223 other tissues |
Genevisiblei | Q5VWG9, HS |
Organism-specific databases
HPAi | ENSG00000165632, Low tissue specificity |
Interactioni
Subunit structurei
Component of the TFIID basal transcription factor complex, composed of TATA-box-binding protein TBP, and a number of TBP-associated factors (TAFs), including TAF1, TAF2, TAF3, TAF4, TAF5, TAF6, TAF7, TAF8, TAF9, TAF10, TAF11, TAF12 and TAF13 (PubMed:33795473).
Interacts with TAF10 via the histone fold (PubMed:11438666).
Interacts with TAF13, TBP, SAP130 and GCN5L2 (PubMed:11438666).
Interacts with TBPL2 (PubMed:11438666).
2 PublicationsBinary interactionsi
Q5VWG9
With | #Exp. | IntAct |
---|---|---|
H3-3B [P84243] | 3 | EBI-1560087,EBI-120658 |
GO - Molecular functioni
- p53 binding Source: Ensembl
- protein heterodimerization activity Source: InterPro
Protein-protein interaction databases
BioGRIDi | 123775, 62 interactors |
ComplexPortali | CPX-915, General transcription factor complex TFIID CPX-930, General transcription factor complex TFIID, TAF4B variant |
CORUMi | Q5VWG9 |
DIPi | DIP-38920N |
IntActi | Q5VWG9, 22 interactors |
MINTi | Q5VWG9 |
STRINGi | 9606.ENSP00000340271 |
Miscellaneous databases
RNActi | Q5VWG9, protein |
Structurei
Secondary structure
3D structure databases
AlphaFoldDBi | Q5VWG9 |
BMRBi | Q5VWG9 |
SMRi | Q5VWG9 |
ModBasei | Search... |
PDBe-KBi | Search... |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 131 – 152 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 176 – 197 | DisorderedSequence analysisAdd BLAST | 22 | |
Regioni | 221 – 358 | DisorderedSequence analysisAdd BLAST | 138 | |
Regioni | 405 – 578 | DisorderedSequence analysisAdd BLAST | 174 | |
Regioni | 603 – 658 | DisorderedSequence analysisAdd BLAST | 56 | |
Regioni | 692 – 748 | DisorderedSequence analysisAdd BLAST | 57 | |
Regioni | 778 – 807 | DisorderedSequence analysisAdd BLAST | 30 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 176 – 194 | Basic and acidic residuesSequence analysisAdd BLAST | 19 | |
Compositional biasi | 260 – 297 | Polar residuesSequence analysisAdd BLAST | 38 | |
Compositional biasi | 317 – 358 | Polar residuesSequence analysisAdd BLAST | 42 | |
Compositional biasi | 414 – 467 | Polar residuesSequence analysisAdd BLAST | 54 | |
Compositional biasi | 488 – 502 | Pro residuesSequence analysisAdd BLAST | 15 | |
Compositional biasi | 505 – 526 | Basic and acidic residuesSequence analysisAdd BLAST | 22 | |
Compositional biasi | 534 – 578 | Basic and acidic residuesSequence analysisAdd BLAST | 45 | |
Compositional biasi | 603 – 648 | Basic and acidic residuesSequence analysisAdd BLAST | 46 | |
Compositional biasi | 710 – 748 | Basic and acidic residuesSequence analysisAdd BLAST | 39 | |
Compositional biasi | 785 – 807 | Pro residuesSequence analysisAdd BLAST | 23 |
Domaini
Sequence similaritiesi
Zinc finger
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Zinc fingeri | 865 – 915 | PHD-typePROSITE-ProRule annotationAdd BLAST | 51 |
Keywords - Domaini
Zinc-fingerPhylogenomic databases
eggNOGi | KOG1973, Eukaryota KOG2389, Eukaryota |
GeneTreei | ENSGT00710000106806 |
HOGENOMi | CLU_014486_0_0_1 |
InParanoidi | Q5VWG9 |
OMAi | FPQPGAR |
OrthoDBi | 826756at2759 |
PhylomeDBi | Q5VWG9 |
TreeFami | TF316513 |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR006565, BTP IPR009072, Histone-fold IPR019786, Zinc_finger_PHD-type_CS IPR011011, Znf_FYVE_PHD IPR001965, Znf_PHD IPR019787, Znf_PHD-finger IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF07524, Bromo_TP, 1 hit PF00628, PHD, 1 hit |
SMARTi | View protein in SMART SM00576, BTP, 1 hit SM00249, PHD, 1 hit |
SUPFAMi | SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS01359, ZF_PHD_1, 1 hit PS50016, ZF_PHD_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
10 20 30 40 50
MCESYSRSLL RVSVAQICQA LGWDSVQLSA CHLLTDVLQR YLQQLGRGCH
60 70 80 90 100
RYSELYGRTD PILDDVGEAF QLMGVSLHEL EDYIHNIEPV TFPHQIPSFP
110 120 130 140 150
VSKNNVLQFP QPGSKDAEER KEYIPDYLPP IVSSQEEEEE EQVPTDGGTS
160 170 180 190 200
AEAMQVPLEE DDELEEEEII NDENFLGKRP LDSPEAEELP AMKRPRLLST
210 220 230 240 250
KGDTLDVVLL EAREPLSSIN TQKIPPMLSP VHVQDSTDLA PPSPEPPMLA
260 270 280 290 300
PVAKSQMPTA KPLETKSFTP KTKTKTSSPG QKTKSPKTAQ SPAMVGSPIR
310 320 330 340 350
SPKTVSKEKK SPGRSKSPKS PKSPKVTTHI PQTPVRPETP NRTPSATLSE
360 370 380 390 400
KISKETIQVK QIQTPPDAGK LNSENQPKKA VVADKTIEAS IDAVIARACA
410 420 430 440 450
EREPDPFEFS SGSESEGDIF TSPKRISGPE CTTPKASTSA NNFTKSGSTP
460 470 480 490 500
LPLSGGTSSS DNSWTMDASI DEVVRKAKLG TPSNMPPNFP YISSPSVSPP
510 520 530 540 550
TPEPLHKVYE EKTKLPSSVE VKKKLKKELK TKMKKKEKQR DREREKDKNK
560 570 580 590 600
DKSKEKDKVK EKEKDKETGR ETKYPWKEFL KEEEADPYKF KIKEFEDVDP
610 620 630 640 650
KVKLKDGLVR KEKEKHKDKK KDREKGKKDK DKREKEKVKD KGREDKMKAP
660 670 680 690 700
APPLVLPPKE LALPLFSPAT ASRVPAMLPS LLPVLPEKLF EEKEKVKEKE
710 720 730 740 750
KKKDKKEKKK KKEKEKEKKE KEREKEKRER EKREKEKEKH KHEKIKVEPV
760 770 780 790 800
ALAPSPVIPR LTLRVGAGQD KIVISKVVPA PEAKPAPSQN RPKTPPPAPA
810 820 830 840 850
PAPGPMLVSP APVPLPLLAQ AAAGPALLPS PGPAASGASA KAPVRSVVTE
860 870 880 890 900
TVSTYVIRDE WGNQIWICPG CNKPDDGSPM IGCDDCDDWY HWPCVGIMTA
910 920
PPEEMQWFCP KCANKKKDKK HKKRKHRAH
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A8I5KR98 | A0A8I5KR98_HUMAN | Transcription initiation factor TFI... | TAF3 | 928 | Annotation score: | ||
A0A8I5QJF0 | A0A8I5QJF0_HUMAN | Transcription initiation factor TFI... | TAF3 | 146 | Annotation score: |
Sequence cautioni
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 23 – 25 | WDS → TRP in CAB56032 (PubMed:17974005).Curated | 3 | |
Sequence conflicti | 533 | M → K in AAH73884 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 537 – 539 | EKQ → KKK in AAH17320 (PubMed:15489334).Curated | 3 | |
Sequence conflicti | 696 | V → P in AAH62352 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 700 | E → K in CAB56032 (PubMed:17974005).Curated | 1 | |
Sequence conflicti | 707 | E → K in AAH62352 (PubMed:15489334).Curated | 1 | |
Sequence conflicti | 713 | E → K in AAH62352 (PubMed:15489334).Curated | 1 |
Natural variant
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Natural variantiVAR_052254 | 349 | S → T. Corresponds to variant dbSNP:rs17366712Ensembl. | 1 | |
Natural variantiVAR_052255 | 442 | N → S1 PublicationCorresponds to variant dbSNP:rs4747647Ensembl. | 1 | |
Natural variantiVAR_052256 | 696 | V → A1 PublicationCorresponds to variant dbSNP:rs1244229Ensembl. | 1 | |
Natural variantiVAR_052257 | 696 | V → L. Corresponds to variant dbSNP:rs10795583Ensembl. | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ292190 mRNA Translation: CAC34475.1 AL390294 Genomic DNA No translation available. AL353754 Genomic DNA No translation available. AL159172 Genomic DNA No translation available. BC017320 mRNA Translation: AAH17320.1 BC045106 mRNA Translation: AAH45106.1 Sequence problems. BC073884 mRNA Translation: AAH73884.1 Different initiation. BC062352 mRNA Translation: AAH62352.1 Different initiation. AL117661 mRNA Translation: CAB56032.1 |
CCDSi | CCDS41487.1 |
PIRi | T17342 |
RefSeqi | NP_114129.1, NM_031923.3 |
Genome annotation databases
Ensembli | ENST00000344293.6; ENSP00000340271.5; ENSG00000165632.9 |
GeneIDi | 83860 |
KEGGi | hsa:83860 |
MANE-Selecti | ENST00000344293.6; ENSP00000340271.5; NM_031923.4; NP_114129.1 |
UCSCi | uc010qbd.4, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AJ292190 mRNA Translation: CAC34475.1 AL390294 Genomic DNA No translation available. AL353754 Genomic DNA No translation available. AL159172 Genomic DNA No translation available. BC017320 mRNA Translation: AAH17320.1 BC045106 mRNA Translation: AAH45106.1 Sequence problems. BC073884 mRNA Translation: AAH73884.1 Different initiation. BC062352 mRNA Translation: AAH62352.1 Different initiation. AL117661 mRNA Translation: CAB56032.1 |
CCDSi | CCDS41487.1 |
PIRi | T17342 |
RefSeqi | NP_114129.1, NM_031923.3 |
3D structure databases
Select the link destinations: PDBei RCSB PDBi PDBji Links Updated | PDB entry | Method | Resolution (Å) | Chain | Positions | PDBsum |
5C13 | X-ray | 2.10 | A/C/E/G | 855-915 | [»] | |
5WXG | X-ray | 1.70 | A | 853-915 | [»] | |
5WXH | X-ray | 1.30 | A/C | 853-915 | [»] | |
5XMY | X-ray | 1.70 | A/C | 853-915 | [»] | |
6MZD | electron microscopy | 9.80 | C | 1-929 | [»] | |
6MZL | electron microscopy | 23.00 | C | 1-929 | [»] | |
7EDX | electron microscopy | 4.50 | c | 1-929 | [»] | |
7EG7 | electron microscopy | 6.20 | c | 1-929 | [»] | |
7EG8 | electron microscopy | 7.40 | c | 1-929 | [»] | |
7EG9 | electron microscopy | 3.70 | c | 1-929 | [»] | |
7EGA | electron microscopy | 4.10 | c | 1-929 | [»] | |
7EGB | electron microscopy | 3.30 | c | 1-929 | [»] | |
7EGC | electron microscopy | 3.90 | c | 1-929 | [»] | |
7EGD | electron microscopy | 6.75 | c | 1-929 | [»] | |
7EGE | electron microscopy | 9.00 | c | 1-929 | [»] | |
7EGF | electron microscopy | 3.16 | c | 1-929 | [»] | |
7EGI | electron microscopy | 9.82 | c | 1-929 | [»] | |
7EGJ | electron microscopy | 8.64 | c | 1-929 | [»] | |
7ENA | electron microscopy | 4.07 | Dc | 1-929 | [»] | |
7ENC | electron microscopy | 4.13 | Dc | 1-929 | [»] | |
AlphaFoldDBi | Q5VWG9 | |||||
BMRBi | Q5VWG9 | |||||
SMRi | Q5VWG9 | |||||
ModBasei | Search... | |||||
PDBe-KBi | Search... |
Protein-protein interaction databases
BioGRIDi | 123775, 62 interactors |
ComplexPortali | CPX-915, General transcription factor complex TFIID CPX-930, General transcription factor complex TFIID, TAF4B variant |
CORUMi | Q5VWG9 |
DIPi | DIP-38920N |
IntActi | Q5VWG9, 22 interactors |
MINTi | Q5VWG9 |
STRINGi | 9606.ENSP00000340271 |
Chemistry databases
ChEMBLi | CHEMBL4523329 |
PTM databases
iPTMneti | Q5VWG9 |
MetOSitei | Q5VWG9 |
PhosphoSitePlusi | Q5VWG9 |
Genetic variation databases
BioMutai | TAF3 |
DMDMi | 74747393 |
Proteomic databases
EPDi | Q5VWG9 |
jPOSTi | Q5VWG9 |
MassIVEi | Q5VWG9 |
MaxQBi | Q5VWG9 |
PaxDbi | Q5VWG9 |
PeptideAtlasi | Q5VWG9 |
PRIDEi | Q5VWG9 |
ProteomicsDBi | 65526 |
Protocols and materials databases
Antibodypediai | 24519, 137 antibodies from 26 providers |
DNASUi | 83860 |
Genome annotation databases
Ensembli | ENST00000344293.6; ENSP00000340271.5; ENSG00000165632.9 |
GeneIDi | 83860 |
KEGGi | hsa:83860 |
MANE-Selecti | ENST00000344293.6; ENSP00000340271.5; NM_031923.4; NP_114129.1 |
UCSCi | uc010qbd.4, human |
Organism-specific databases
CTDi | 83860 |
DisGeNETi | 83860 |
GeneCardsi | TAF3 |
HGNCi | HGNC:17303, TAF3 |
HPAi | ENSG00000165632, Low tissue specificity |
MIMi | 606576, gene |
neXtProti | NX_Q5VWG9 |
OpenTargetsi | ENSG00000165632 |
PharmGKBi | PA38222 |
VEuPathDBi | HostDB:ENSG00000165632 |
GenAtlasi | Search... |
Phylogenomic databases
eggNOGi | KOG1973, Eukaryota KOG2389, Eukaryota |
GeneTreei | ENSGT00710000106806 |
HOGENOMi | CLU_014486_0_0_1 |
InParanoidi | Q5VWG9 |
OMAi | FPQPGAR |
OrthoDBi | 826756at2759 |
PhylomeDBi | Q5VWG9 |
TreeFami | TF316513 |
Enzyme and pathway databases
PathwayCommonsi | Q5VWG9 |
Reactomei | R-HSA-167161, HIV Transcription Initiation R-HSA-167162, RNA Polymerase II HIV Promoter Escape R-HSA-167172, Transcription of the HIV genome R-HSA-674695, RNA Polymerase II Pre-transcription Events R-HSA-6804756, Regulation of TP53 Activity through Phosphorylation R-HSA-73776, RNA Polymerase II Promoter Escape R-HSA-73779, RNA Polymerase II Transcription Pre-Initiation And Promoter Opening R-HSA-75953, RNA Polymerase II Transcription Initiation R-HSA-76042, RNA Polymerase II Transcription Initiation And Promoter Clearance |
SignaLinki | Q5VWG9 |
SIGNORi | Q5VWG9 |
Miscellaneous databases
BioGRID-ORCSi | 83860, 186 hits in 1098 CRISPR screens |
ChiTaRSi | TAF3, human |
GeneWikii | TAF3 |
GenomeRNAii | 83860 |
Pharosi | Q5VWG9, Tbio |
PROi | PR:Q5VWG9 |
RNActi | Q5VWG9, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSG00000165632, Expressed in tendon of biceps brachii and 223 other tissues |
Genevisiblei | Q5VWG9, HS |
Family and domain databases
Gene3Di | 1.10.20.10, 1 hit 3.30.40.10, 1 hit |
InterProi | View protein in InterPro IPR006565, BTP IPR009072, Histone-fold IPR019786, Zinc_finger_PHD-type_CS IPR011011, Znf_FYVE_PHD IPR001965, Znf_PHD IPR019787, Znf_PHD-finger IPR013083, Znf_RING/FYVE/PHD |
Pfami | View protein in Pfam PF07524, Bromo_TP, 1 hit PF00628, PHD, 1 hit |
SMARTi | View protein in SMART SM00576, BTP, 1 hit SM00249, PHD, 1 hit |
SUPFAMi | SSF57903, SSF57903, 1 hit |
PROSITEi | View protein in PROSITE PS01359, ZF_PHD_1, 1 hit PS50016, ZF_PHD_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | TAF3_HUMAN | |
Accessioni | Q5VWG9Primary (citable) accession number: Q5VWG9 Secondary accession number(s): Q05DA0 Q9UFI8 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 11, 2006 |
Last sequence update: | December 7, 2004 | |
Last modified: | May 25, 2022 | |
This is version 162 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
Miscellaneousi
Keywords - Technical termi
3D-structure, Reference proteomeDocuments
- Human chromosome 10
Human chromosome 10: entries, gene names and cross-references to MIM - Human entries with genetic variants
List of human entries with genetic variants - Human variants curated from literature reports
Index of human variants curated from literature reports - MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot - PDB cross-references
Index of Protein Data Bank (PDB) cross-references - SIMILARITY comments
Index of protein domains and families