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UniProtKB - Q5VUG0 (SMBT2_HUMAN)

Entry version 136 (26 Feb 2020)
Sequence version 1 (07 Dec 2004)
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Protein

Scm-like with four MBT domains protein 2

Gene

SFMBT2

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Transcriptional repressor of HOXB13 gene.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

  • histone binding Source: UniProtKB
  • transcription corepressor activity Source: InterPro
Complete GO annotation on QuickGO ...

GO - Biological processi

Complete GO annotation on QuickGO ...

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionRepressor

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Scm-like with four MBT domains protein 2
Short name:
Scm-like with 4 MBT domains protein 2
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:SFMBT2
Synonyms:KIAA1617
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...HGNCi		HGNC:20256 SFMBT2

Online Mendelian Inheritance in Man (OMIM)

More...MIMi		615392 gene

neXtProt; the human protein knowledge platform

More...neXtProti		NX_Q5VUG0

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

Open Targets

More...OpenTargetsi		ENSG00000198879

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...PharmGKBi		PA134866013

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...Pharosi		Q5VUG0 Tdark

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...BioMutai		SFMBT2

Domain mapping of disease mutations (DMDM)

More...DMDMi		67461560

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00000719691 – 894Scm-like with four MBT domains protein 2Add BLAST894

Proteomic databases

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...MassIVEi		Q5VUG0

MaxQB - The MaxQuant DataBase

More...MaxQBi		Q5VUG0

PaxDb, a database of protein abundance averages across all three domains of life

More...PaxDbi		Q5VUG0

PeptideAtlas

More...PeptideAtlasi		Q5VUG0

PRoteomics IDEntifications database

More...PRIDEi		Q5VUG0

ProteomicsDB: a multi-organism proteome resource

More...ProteomicsDBi		65417

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...iPTMneti		Q5VUG0

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...PhosphoSitePlusi		Q5VUG0

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...Bgeei		ENSG00000198879 Expressed in corpus callosum and 177 other tissues

ExpressionAtlas, Differential and Baseline Expression

More...ExpressionAtlasi		Q5VUG0 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...Genevisiblei		Q5VUG0 HS

Organism-specific databases

Human Protein Atlas

More...HPAi		HPA035447
HPA035448
HPA070388

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with YY1.

Interacts with methylated histones H3K9me2 and H4K20me2, but not with H3K4me2, nor H3K9Ac.

1 Publication

<p>This subsection of the '<a href="http://www.uniprot.org/help/interaction%5Fsection%27">Interaction</a> section provides information about binary protein-protein interactions. The data presented in this section are a quality-filtered subset of binary interactions automatically derived from the <a href="http://www.ebi.ac.uk/intact/">IntAct database</a>. It is updated on a monthly basis. Each binary interaction is displayed on a separate line.<p><a href='/help/binary_interactions' target='_top'>More...</a></p>Binary interactionsi

Show more details

GO - Molecular functioni

Complete GO annotation on QuickGO ...

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...BioGridi		121736, 6 interactors

Protein interaction database and analysis system

More...IntActi		Q5VUG0, 9 interactors

STRING: functional protein association networks

More...STRINGi		9606.ENSP00000380353

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...RNActi		Q5VUG0 protein

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

Secondary structure

1894
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...SMRi		Q5VUG0

Database of comparative protein structure models

More...ModBasei		Search...

Protein Data Bank in Europe - Knowledge Base

More...PDBe-KBi		Search...

Miscellaneous databases

Relative evolutionary importance of amino acids within a protein sequence

More...EvolutionaryTracei		Q5VUG0

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati44 – 144MBT 1Add BLAST101
Repeati152 – 256MBT 2Add BLAST105
Repeati266 – 372MBT 3Add BLAST107
Repeati380 – 477MBT 4Add BLAST98
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini824 – 887SAMAdd BLAST64

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...eggNOGi		ENOG410IMEX Eukaryota
ENOG410XSJM LUCA

Ensembl GeneTree

More...GeneTreei		ENSGT00940000158123

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...HOGENOMi		CLU_005352_0_0_1

InParanoid: Eukaryotic Ortholog Groups

More...InParanoidi		Q5VUG0

Identification of Orthologs from Complete Genome Data

More...OMAi		KMTSEWK

Database of Orthologous Groups

More...OrthoDBi		237430at2759

Database for complete collections of gene phylogenies

More...PhylomeDBi		Q5VUG0

TreeFam database of animal gene trees

More...TreeFami		TF316498

Family and domain databases

Conserved Domains Database

More...CDDi		cd09581 SAM_Scm-like-4MBT1_2, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...Gene3Di		1.10.150.50, 1 hit
1.20.1380.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...InterProi		View protein in InterPro
IPR004092 Mbt
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR037604 Scm-like-4MBT1/2_SAM
IPR021987 SLED
IPR038348 SLED_sf

Pfam protein domain database

More...Pfami		View protein in Pfam
PF02820 MBT, 4 hits
PF00536 SAM_1, 1 hit
PF12140 SLED, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...SMARTi		View protein in SMART
SM00561 MBT, 4 hits
SM00454 SAM, 1 hit

Superfamily database of structural and functional annotation

More...SUPFAMi		SSF47769 SSF47769, 1 hit

PROSITE; a protein domain and family database

More...PROSITEi		View protein in PROSITE
PS51079 MBT, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All

Q5VUG0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MESTLSASNM QDPSSSPLEK CLGSANGNGD LDSEEGSSLE ETGFNWGEYL 
        60         70         80         90        100
EETGASAAPH TSFKHVEISI QSNFQPGMKL EVANKNNPDT YWVATIITTC 
       110        120        130        140        150
GQLLLLRYCG YGEDRRADFW CDVVIADLHP VGWCTQNNKV LMPPDAIKEK 
       160        170        180        190        200
YTDWTEFLIR DLTGSRTAPA NLLEGPLRGK GPIDLITVGS LIELQDSQNP 
       210        220        230        240        250
FQYWIVSVIE NVGGRLRLRY VGLEDTESYD QWLFYLDYRL RPVGWCQENK 
       260        270        280        290        300
YRMDPPSEIY PLKMASEWKC TLEKSLIDAA KFPLPMEVFK DHADLRSHFF 
       310        320        330        340        350
TVGMKLETVN MCEPFYISPA SVTKVFNNHF FQVTIDDLRP EPSKLSMLCH 
       360        370        380        390        400
ADSLGILPVQ WCLKNGVSLT PPKGYSGQDF DWADYHKQHG AQEAPPFCFR 
       410        420        430        440        450
NTSFSRGFTK NMKLEAVNPR NPGELCVASV VSVKGRLMWL HLEGLQTPVP 
       460        470        480        490        500
EVIVDVESMD IFPVGWCEAN SYPLTAPHKT VSQKKRKIAV VQPEKQLPPT 
       510        520        530        540        550
VPVKKIPHDL CLFPHLDTTG TVNGKYCCPQ LFINHRCFSG PYLNKGRIAE 
       560        570        580        590        600
LPQSVGPGKC VLVLKEVLSM IINAAYKPGR VLRELQLVED PHWNFQEETL 
       610        620        630        640        650
KAKYRGKTYR AVVKIVRTSD QVANFCRRVC AKLECCPNLF SPVLISENCP 
       660        670        680        690        700
ENCSIHTKTK YTYYYGKRKK ISKPPIGESN PDSGHPKPAR RRKRRKSIFV 
       710        720        730        740        750
QKKRRSSAVD FTAGSGEESE EEDADAMDDD TASEETGSEL RDDQTDTSSA 
       760        770        780        790        800
EVPSARPRRA VTLRSGSEPV RRPPPERTRR GRGAPAASSA EEGEKCPPTK 
       810        820        830        840        850
PEGTEDTKQE EEERLVLESN PLEWTVTDVV RFIKLTDCAP LAKIFQEQDI 
       860        870        880        890 
DGQALLLLTL PTVQECMELK LGPAIKLCHQ IERVKVAFYA QYAN
Length:894
Mass (Da):100,563
Last modified:December 7, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i20EFF7F789F41787
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5T981Q5T981_HUMAN
Scm-like with four MBT domains prot...
SFMBT2
186Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q5T980Q5T980_HUMAN
Scm-like with four MBT domains prot...
SFMBT2
160Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

<p>This subsection of the 'Sequence' section reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.<p><a href='/help/sequence_caution' target='_top'>More...</a></p>Sequence cautioni

The sequence BAB13443 differs from that shown. Reason: Erroneous initiation. Extended N-terminus.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_051362675P → R. Corresponds to variant dbSNP:rs3740212Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...EMBLi

GenBank nucleotide sequence database

More...GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...DDBJi
Links Updated
AB046837 mRNA Translation: BAB13443.1 Different initiation.
AL590095 Genomic DNA No translation available.
AL158046 Genomic DNA No translation available.
AL139125 Genomic DNA No translation available.
AL138771 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86385.1
BC152430 mRNA Translation: AAI52431.1

The Consensus CDS (CCDS) project

More...CCDSi		CCDS31138.1

NCBI Reference Sequences

More...RefSeqi		NP_001018049.1, NM_001018039.1
NP_001025051.1, NM_001029880.2
XP_011517913.1, XM_011519611.1
XP_016871955.1, XM_017016466.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...Ensembli		ENST00000361972; ENSP00000355109; ENSG00000198879
ENST00000397167; ENSP00000380353; ENSG00000198879

Database of genes from NCBI RefSeq genomes

More...GeneIDi		57713

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...KEGGi		hsa:57713

UCSC genome browser

More...UCSCi		uc001ijn.2 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB046837 mRNA Translation: BAB13443.1 Different initiation.
AL590095 Genomic DNA No translation available.
AL158046 Genomic DNA No translation available.
AL139125 Genomic DNA No translation available.
AL138771 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86385.1
BC152430 mRNA Translation: AAI52431.1
CCDSiCCDS31138.1
RefSeqiNP_001018049.1, NM_001018039.1
NP_001025051.1, NM_001029880.2
XP_011517913.1, XM_011519611.1
XP_016871955.1, XM_017016466.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...PDBei

Protein Data Bank RCSB

More...RCSB PDBi

Protein Data Bank Japan

More...PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1WJRNMR-A182-295[»]
SMRiQ5VUG0
ModBaseiSearch...
PDBe-KBiSearch...

Protein-protein interaction databases

BioGridi121736, 6 interactors
IntActiQ5VUG0, 9 interactors
STRINGi9606.ENSP00000380353

PTM databases

iPTMnetiQ5VUG0
PhosphoSitePlusiQ5VUG0

Polymorphism and mutation databases

BioMutaiSFMBT2
DMDMi67461560

Proteomic databases

MassIVEiQ5VUG0
MaxQBiQ5VUG0
PaxDbiQ5VUG0
PeptideAtlasiQ5VUG0
PRIDEiQ5VUG0
ProteomicsDBi65417

Protocols and materials databases

The DNASU plasmid repository

More...DNASUi		57713

Genome annotation databases

EnsembliENST00000361972; ENSP00000355109; ENSG00000198879
ENST00000397167; ENSP00000380353; ENSG00000198879
GeneIDi57713
KEGGihsa:57713
UCSCiuc001ijn.2 human

Organism-specific databases

Comparative Toxicogenomics Database

More...CTDi		57713

GeneCards: human genes, protein and diseases

More...GeneCardsi		SFMBT2
HGNCiHGNC:20256 SFMBT2
HPAiHPA035447
HPA035448
HPA070388
MIMi615392 gene
neXtProtiNX_Q5VUG0
OpenTargetsiENSG00000198879
PharmGKBiPA134866013

Human Unidentified Gene-Encoded large proteins database

More...HUGEi		Search...

GenAtlas: human gene database

More...GenAtlasi		Search...

Phylogenomic databases

eggNOGiENOG410IMEX Eukaryota
ENOG410XSJM LUCA
GeneTreeiENSGT00940000158123
HOGENOMiCLU_005352_0_0_1
InParanoidiQ5VUG0
OMAiKMTSEWK
OrthoDBi237430at2759
PhylomeDBiQ5VUG0
TreeFamiTF316498

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...ChiTaRSi		SFMBT2 human
EvolutionaryTraceiQ5VUG0

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...GenomeRNAii		57713
PharosiQ5VUG0 Tdark

Protein Ontology

More...PROi		PR:Q5VUG0
RNActiQ5VUG0 protein

The Stanford Online Universal Resource for Clones and ESTs

More...SOURCEi		Search...

Gene expression databases

BgeeiENSG00000198879 Expressed in corpus callosum and 177 other tissues
ExpressionAtlasiQ5VUG0 baseline and differential
GenevisibleiQ5VUG0 HS

Family and domain databases

CDDicd09581 SAM_Scm-like-4MBT1_2, 1 hit
Gene3Di1.10.150.50, 1 hit
1.20.1380.20, 1 hit
InterProiView protein in InterPro
IPR004092 Mbt
IPR001660 SAM
IPR013761 SAM/pointed_sf
IPR037604 Scm-like-4MBT1/2_SAM
IPR021987 SLED
IPR038348 SLED_sf
PfamiView protein in Pfam
PF02820 MBT, 4 hits
PF00536 SAM_1, 1 hit
PF12140 SLED, 1 hit
SMARTiView protein in SMART
SM00561 MBT, 4 hits
SM00454 SAM, 1 hit
SUPFAMiSSF47769 SSF47769, 1 hit
PROSITEiView protein in PROSITE
PS51079 MBT, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...ProtoNeti		Search...

MobiDB: a database of protein disorder and mobility annotations

More...MobiDBi		Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiSMBT2_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5VUG0
Secondary accession number(s): A7MD09, Q9HCF5
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: December 7, 2004
Last modified: February 26, 2020
This is version 136 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structure, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  3. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
  4. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  5. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
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