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Entry version 122 (16 Oct 2019)
Sequence version 1 (07 Dec 2004)
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Protein

Protein FAM171A1

Gene

FAM171A1

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Involved in the regulation of the cytoskeletal dynamics, plays a role in actin stress fiber formation.1 Publication

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Protein FAM171A1Curated
Alternative name(s):
Astroprincin1 Publication
Short name:
APCN1 Publication
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:FAM171A1Imported
Synonyms:APCN1 Publication, C10orf38
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000005640 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 10

Organism-specific databases

Human Gene Nomenclature Database

More...
HGNCi
HGNC:23522 FAM171A1

neXtProt; the human protein knowledge platform

More...
neXtProti
NX_Q5VUB5

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the subcellular compartment where each non-membrane region of a membrane-spanning protein is found.<p><a href='/help/topo_dom' target='_top'>More...</a></p>Topological domaini22 – 303Extracellular1 PublicationAdd BLAST282
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei304 – 324HelicalSequence analysisAdd BLAST21
Topological domaini325 – 890Cytoplasmic1 PublicationAdd BLAST566

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Cell membrane, Membrane

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/manual/pathology_and_biotech_section">'Pathology and Biotech'</a> section describes the effect of the experimental mutation of one or more amino acid(s) on the biological properties of the protein.<p><a href='/help/mutagen' target='_top'>More...</a></p>Mutagenesisi136S → A: No effect on glycosylation. 1 Publication1
Mutagenesisi159N → A: Decreases glycosylation levels. Abolishes glycosylation; when associated with A-194. 1 Publication1
Mutagenesisi190N → A: No effect on glycosylation. 1 Publication1
Mutagenesisi194N → A: Decreases glycosylation levels. Abolishes glycosylation; when associated with A-159. 1 Publication1

Organism-specific databases

DisGeNET

More...
DisGeNETi
221061

Open Targets

More...
OpenTargetsi
ENSG00000148468

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA162387176

Miscellaneous databases

Pharos NIH Druggable Genome Knowledgebase

More...
Pharosi
Q5VUB5

Polymorphism and mutation databases

BioMuta curated single-nucleotide variation and disease association database

More...
BioMutai
FAM171A1

Domain mapping of disease mutations (DMDM)

More...
DMDMi
74747078

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 21Sequence analysisAdd BLAST21
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_000027426322 – 890Protein FAM171A1Add BLAST869

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi159N-linked (GlcNAc...) asparagine2 Publications1
Glycosylationi190N-linked (GlcNAc...) asparagineSequence analysis1
Glycosylationi194N-linked (GlcNAc...) asparagine1 Publication1
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei358PhosphoserineCombined sources1
Modified residuei360PhosphoserineCombined sources1
Modified residuei371PhosphoserineCombined sources1
Modified residuei422PhosphoserineCombined sources1
Modified residuei443PhosphoserineCombined sources1
Modified residuei525PhosphoserineCombined sources1
Modified residuei849PhosphoserineCombined sources1
Modified residuei855PhosphoserineCombined sources1

Keywords - PTMi

Glycoprotein, Phosphoprotein

Proteomic databases

Encyclopedia of Proteome Dynamics

More...
EPDi
Q5VUB5

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
Q5VUB5

MassIVE - Mass Spectrometry Interactive Virtual Environment

More...
MassIVEi
Q5VUB5

MaxQB - The MaxQuant DataBase

More...
MaxQBi
Q5VUB5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
Q5VUB5

PeptideAtlas

More...
PeptideAtlasi
Q5VUB5

PRoteomics IDEntifications database

More...
PRIDEi
Q5VUB5

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
65405

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
Q5VUB5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
Q5VUB5

SwissPalm database of S-palmitoylation events

More...
SwissPalmi
Q5VUB5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the ‘Expression’ section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’. <br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Expressed in heart, brain, liver, skeletal muscle, kidney and pancreas (PubMed:30312582). In brain, expressed by glia, pyramidal neurons and astrocytes (at protein level) (PubMed:30312582). Highly expressed in placental trophoblasts (PubMed:30312582).1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSG00000148468 Expressed in 239 organ(s), highest expression level in nucleus accumbens

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
Q5VUB5 baseline and differential

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
Q5VUB5 HS

Organism-specific databases

Human Protein Atlas

More...
HPAi
HPA051345

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Interacts with ADAM10, NSG1 and OAZ1.

1 Publication

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
128680, 10 interactors

Protein interaction database and analysis system

More...
IntActi
Q5VUB5, 9 interactors

STRING: functional protein association networks

More...
STRINGi
9606.ENSP00000367356

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
Q5VUB5

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

<p>This subsection of the ‘Family and domains’ section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the FAM171 family.Curated

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
ENOG410IKM3 Eukaryota
ENOG410ZV9V LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00950000183184

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231925

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
Q5VUB5

Identification of Orthologs from Complete Genome Data

More...
OMAi
GEADMHT

Database of Orthologous Groups

More...
OrthoDBi
168316at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
Q5VUB5

TreeFam database of animal gene trees

More...
TreeFami
TF331338

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR018890 Uncharacterised_FAM171

The PANTHER Classification System

More...
PANTHERi
PTHR31626 PTHR31626, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF10577 UPF0560, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is in its mature form or if it represents the precursor.<p><a href='/help/sequence_processing' target='_top'>More...</a></p>Sequence processingi: The displayed sequence is further processed into a mature form.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

Q5VUB5-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSRSATLLLC LLGCHVWKAV TKTLREPGAG AQEVTLKVHI SDASTHQPVA
60 70 80 90 100
DALIEIFTNQ ASIASGTSGT DGVAFIKFQY KLGSQLIVTA SKHAYVPNSA
110 120 130 140 150
PWKPIRLPVF SSLSLGLLPE RSATLMVYED VVQIVSGFQG ARPQPRVHFQ
160 170 180 190 200
RRALRLPENT SYSDLTAFLT AASSPSEVDS FPYLRGLDGN GTGNSTRHDL
210 220 230 240 250
TPVTAVSVHL LSSNGTPVLV DGPIYVTVPL ATQSSLRHNA YVAAWRFDQK
260 270 280 290 300
LGTWLKSGLG LVHQEGSQLT WTYIAPQLGY WVAAMSPPIP GPVVTQDITT
310 320 330 340 350
YHTVFLLAIL GGMAFILLVL LCLLLYYCRR KCLKPRQHHR KLQLPAGLES
360 370 380 390 400
SKRDQSTSMS HINLLFSRRA SEFPGPLSVT SHGRPEAPGT KELMSGVHLE
410 420 430 440 450
MMSPGGEGDL HTPMLKLSYS TSQEFSSREE LLSCKEEDKS QISFDNLTPS
460 470 480 490 500
GTLGKDYHKS VEVFPLKARK SMEREGYESS GNDDYRGSYN TVLSQPLFEK
510 520 530 540 550
QDREGPASTG SKLTIQEHLY PAPSSPEKEQ LLDRRPTECM MSRSVDHLER
560 570 580 590 600
PTSFPRPGQL ICCSSVDQVN DSVYRKVLPA LVIPAHYMKL PGDHSYVSQP
610 620 630 640 650
LVVPADQQLE IERLQAELSN PHAGIFPHPS SQIQPQPLSS QAISQQHLQD
660 670 680 690 700
AGTREWSPQN ASMSESLSIP ASLNDAALAQ MNSEVQLLTE KALMELGGGK
710 720 730 740 750
PLPHPRAWFV SLDGRSNAHV RHSYIDLQRA GRNGSNDASL DSGVDMNEPK
760 770 780 790 800
SARKGRGDAL SLQQNYPPVQ EHQQKEPRAP DSTAYTQLVY LDDVEQSGSE
810 820 830 840 850
CGTTVCTPED SALRCLLEGS SRRSGGQLPS LQEETTRRTA DAPSEPAASP
860 870 880 890
HQRRSAHEEE EDDDDDDQGE DKKSPWQKRE ERPLMAFNIK
Length:890
Mass (Da):97,854
Last modified:December 7, 2004 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iA0718E29A639FB72
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5SW12Q5SW12_HUMAN
Protein FAM171A1
FAM171A1
198Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti118L → P in AAI09304 (PubMed:15489334).Curated1
Sequence conflicti592G → R in AAH34232 (PubMed:15489334).Curated1
Sequence conflicti670P → Q in AAH34232 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Sequence’ section describes natural variant(s) of the protein sequence.<p><a href='/help/variant' target='_top'>More...</a></p>Natural variantiVAR_030220465P → S1 PublicationCorresponds to variant dbSNP:rs3814165Ensembl.1

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AY683003 mRNA Translation: AAV85904.1
AL590365 Genomic DNA No translation available.
AL139338 Genomic DNA No translation available.
AL607028 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86237.1
BC034232 mRNA Translation: AAH34232.1
BC109302 mRNA Translation: AAI09303.1
BC109303 mRNA Translation: AAI09304.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS31154.1

NCBI Reference Sequences

More...
RefSeqi
NP_001010924.1, NM_001010924.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENST00000378116; ENSP00000367356; ENSG00000148468

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
221061

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
hsa:221061

UCSC genome browser

More...
UCSCi
uc001iob.4 human

Keywords - Coding sequence diversityi

Polymorphism

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY683003 mRNA Translation: AAV85904.1
AL590365 Genomic DNA No translation available.
AL139338 Genomic DNA No translation available.
AL607028 Genomic DNA No translation available.
CH471072 Genomic DNA Translation: EAW86237.1
BC034232 mRNA Translation: AAH34232.1
BC109302 mRNA Translation: AAI09303.1
BC109303 mRNA Translation: AAI09304.1
CCDSiCCDS31154.1
RefSeqiNP_001010924.1, NM_001010924.1

3D structure databases

SMRiQ5VUB5
ModBaseiSearch...

Protein-protein interaction databases

BioGridi128680, 10 interactors
IntActiQ5VUB5, 9 interactors
STRINGi9606.ENSP00000367356

PTM databases

iPTMnetiQ5VUB5
PhosphoSitePlusiQ5VUB5
SwissPalmiQ5VUB5

Polymorphism and mutation databases

BioMutaiFAM171A1
DMDMi74747078

Proteomic databases

EPDiQ5VUB5
jPOSTiQ5VUB5
MassIVEiQ5VUB5
MaxQBiQ5VUB5
PaxDbiQ5VUB5
PeptideAtlasiQ5VUB5
PRIDEiQ5VUB5
ProteomicsDBi65405

Genome annotation databases

EnsembliENST00000378116; ENSP00000367356; ENSG00000148468
GeneIDi221061
KEGGihsa:221061
UCSCiuc001iob.4 human

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
221061
DisGeNETi221061

GeneCards: human genes, protein and diseases

More...
GeneCardsi
FAM171A1
HGNCiHGNC:23522 FAM171A1
HPAiHPA051345
neXtProtiNX_Q5VUB5
OpenTargetsiENSG00000148468
PharmGKBiPA162387176

GenAtlas: human gene database

More...
GenAtlasi
Search...

Phylogenomic databases

eggNOGiENOG410IKM3 Eukaryota
ENOG410ZV9V LUCA
GeneTreeiENSGT00950000183184
HOGENOMiHOG000231925
InParanoidiQ5VUB5
OMAiGEADMHT
OrthoDBi168316at2759
PhylomeDBiQ5VUB5
TreeFamiTF331338

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
FAM171A1 human

Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens

More...
GenomeRNAii
221061
PharosiQ5VUB5

Protein Ontology

More...
PROi
PR:Q5VUB5

Gene expression databases

BgeeiENSG00000148468 Expressed in 239 organ(s), highest expression level in nucleus accumbens
ExpressionAtlasiQ5VUB5 baseline and differential
GenevisibleiQ5VUB5 HS

Family and domain databases

InterProiView protein in InterPro
IPR018890 Uncharacterised_FAM171
PANTHERiPTHR31626 PTHR31626, 1 hit
PfamiView protein in Pfam
PF10577 UPF0560, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiF1711_HUMAN
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: Q5VUB5
Secondary accession number(s): D3DRT9, Q32M49, Q8N4I0
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 6, 2007
Last sequence update: December 7, 2004
Last modified: October 16, 2019
This is version 122 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Human polymorphisms and disease mutations
    Index of human polymorphisms and disease mutations
  3. Human chromosome 10
    Human chromosome 10: entries, gene names and cross-references to MIM
  4. Human entries with polymorphisms or disease mutations
    List of human entries with polymorphisms or disease mutations
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