UniProtKB - Q5VU21 (Q5VU21_HUMAN)
Protein
Submitted name:
PAI-1 mRNA-binding protein variant
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- mRNA 3'-UTR binding Source: InterPro
Keywordsi
Molecular function | RNA-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: PAI-1 mRNA-binding protein variantImportedSubmitted name: cDNA, FLJ92551, Homo sapiens PAI-1 mRNA-binding protein (PAI-RBP1), mRNAImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000142864.14 |
Expressioni
Gene expression databases
Bgeei | ENSG00000142864, Expressed in testis and 247 other tissues |
ExpressionAtlasi | Q5VU21, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 189 – 293 | HABP4_PAI-RBP1InterPro annotationAdd BLAST | 105 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 33 – 266 | DisorderedSequence analysisAdd BLAST | 234 | |
Regioni | 309 – 387 | DisorderedSequence analysisAdd BLAST | 79 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 55 – 69 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 95 – 161 | PolyampholyteSequence analysisAdd BLAST | 67 | |
Compositional biasi | 176 – 213 | PolyampholyteSequence analysisAdd BLAST | 38 | |
Compositional biasi | 236 – 266 | PolyampholyteSequence analysisAdd BLAST | 31 | |
Compositional biasi | 309 – 328 | PolyampholyteSequence analysisAdd BLAST | 20 |
Phylogenomic databases
HOGENOMi | CLU_037366_2_1_1 |
OMAi | QNRKREF |
Family and domain databases
InterProi | View protein in InterPro IPR039764, HABP4/SERBP1 IPR006861, HABP4_PAIRBP1-bd IPR032381, IHABP4_N IPR027205, SERBP1 |
PANTHERi | PTHR12299, PTHR12299, 1 hit PTHR12299:SF29, PTHR12299:SF29, 1 hit |
Pfami | View protein in Pfam PF04774, HABP4_PAI-RBP1, 1 hit PF16174, IHABP4_N, 1 hit |
SMARTi | View protein in SMART SM01233, HABP4_PAI-RBP1, 1 hit |
i Sequence
Sequence statusi: Complete.
Q5VU21-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MPGHLQEGFG CVVTNRFDQL FDDESDPFEV LKAAENKKKE AGGGGVGGPG
60 70 80 90 100
AKSAAQAAAQ TNSNAAGKQL RKESQKDRKN PLPPSVGVVD KKEETQPPVA
110 120 130 140 150
LKKEGIRRVG RRPDQQLQGE GKIIDRRPER RPPRERRFEK PLEEKGEGGE
160 170 180 190 200
FSVDRPIIDR PIRGRGGLGR GRGGRGRGMG RGDGFDSRGK REFDRHSGSD
210 220 230 240 250
RSGLKHEDKR GGSGSHNWGT VKDELTDLDQ SNVTEETPEG EEHHPVADTE
260 270 280 290 300
NKENEVEEVK EEGPKEMTLD EWKAIQNKDR AKVEFNIRKP NEGADGQWKK
310 320 330 340 350
GFVLHKSKSE EAHAEDSVMD HHFRKPANDI TSQLEINFGD LGRPGRGGRG
360 370 380
GRGGRGRGGR PNRGSRTDKS SASAPDVDDP EAFPALA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK222955 mRNA Translation: BAD96675.1 AK223138 mRNA Translation: BAD96858.1 AK312256 mRNA Translation: BAG35188.1 |
RefSeqi | NP_056455.3, NM_015640.3 |
Genome annotation databases
GeneIDi | 26135 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK222955 mRNA Translation: BAD96675.1 AK223138 mRNA Translation: BAD96858.1 AK312256 mRNA Translation: BAG35188.1 |
RefSeqi | NP_056455.3, NM_015640.3 |
3D structure databases
SMRi | Q5VU21 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q5VU21, 3 interactors |
Protocols and materials databases
Antibodypediai | 19619, 349 antibodies |
DNASUi | 26135 |
Genome annotation databases
GeneIDi | 26135 |
Organism-specific databases
CTDi | 26135 |
PharmGKBi | PA413 |
VEuPathDBi | HostDB:ENSG00000142864.14 |
Phylogenomic databases
HOGENOMi | CLU_037366_2_1_1 |
OMAi | QNRKREF |
Miscellaneous databases
BioGRID-ORCSi | 26135, 275 hits in 967 CRISPR screens |
GenomeRNAii | 26135 |
Gene expression databases
Bgeei | ENSG00000142864, Expressed in testis and 247 other tissues |
ExpressionAtlasi | Q5VU21, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR039764, HABP4/SERBP1 IPR006861, HABP4_PAIRBP1-bd IPR032381, IHABP4_N IPR027205, SERBP1 |
PANTHERi | PTHR12299, PTHR12299, 1 hit PTHR12299:SF29, PTHR12299:SF29, 1 hit |
Pfami | View protein in Pfam PF04774, HABP4_PAI-RBP1, 1 hit PF16174, IHABP4_N, 1 hit |
SMARTi | View protein in SMART SM01233, HABP4_PAI-RBP1, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5VU21_HUMAN | |
Accessioni | Q5VU21Primary (citable) accession number: Q5VU21 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | May 10, 2005 |
Last sequence update: | May 10, 2005 | |
Last modified: | April 7, 2021 | |
This is version 134 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |