PAI-1 mRNA-binding protein variant

Functionⁱ

GO - Molecular functionⁱ

mRNA 3'-UTR binding Source: InterPro

View the complete GO annotation on QuickGO ...

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: PAI-1 mRNA-binding protein variantImported Submitted name: cDNA, FLJ92551, Homo sapiens PAI-1 mRNA-binding protein (PAI-RBP1), mRNAImported
Organismⁱ	Homo sapiens (Human)Imported
Taxonomic identifierⁱ	9606 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Organism-specific databases

EuPathDBⁱ	HostDB:ENSG00000142864.14

EuPathDBⁱ

HostDB:ENSG00000142864.14

Subcellular locationⁱ

GO - Cellular component

Pathology & Biotechⁱ

Organism-specific databases

PharmGKBⁱ	PA413

PharmGKBⁱ

PA413

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSG00000142864 Expressed in 236 organ(s), highest expression level in testis

Bgeeⁱ

ENSG00000142864 Expressed in 236 organ(s), highest expression level in testis

Interactionⁱ

Protein-protein interaction databases

IntActⁱ	Q5VU21, 3 interactors Q5VU21, 3 interactors

IntActⁱ

Q5VU21, 3 interactors
Q5VU21, 3 interactors

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Domainⁱ	189 – 293	HABP4_PAI-RBP1InterPro annotationAdd BLAST		105

Phylogenomic databases

HOVERGENⁱ	HBG056357

HOVERGENⁱ

HBG056357

Family and domain databases

InterProⁱ	View protein in InterPro IPR039764 HABP4/SERBP1 IPR006861 HABP4_PAIRBP1-bd IPR032381 IHABP4_N IPR027205 SERBP1
PANTHERⁱ	PTHR12299 PTHR12299, 1 hit PTHR12299:SF29 PTHR12299:SF29, 1 hit
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF04774 HABP4_PAI-RBP1, 1 hit PF16174 IHABP4_N, 1 hit
SMARTⁱ	View protein in SMART SM01233 HABP4_PAI-RBP1, 1 hit

Sequenceⁱ

Sequence statusⁱ: Complete.

Q5VU21-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MPGHLQEGFG CVVTNRFDQL FDDESDPFEV LKAAENKKKE AGGGGVGGPG 
        60         70         80         90        100
AKSAAQAAAQ TNSNAAGKQL RKESQKDRKN PLPPSVGVVD KKEETQPPVA 
       110        120        130        140        150
LKKEGIRRVG RRPDQQLQGE GKIIDRRPER RPPRERRFEK PLEEKGEGGE 
       160        170        180        190        200
FSVDRPIIDR PIRGRGGLGR GRGGRGRGMG RGDGFDSRGK REFDRHSGSD 
       210        220        230        240        250
RSGLKHEDKR GGSGSHNWGT VKDELTDLDQ SNVTEETPEG EEHHPVADTE 
       260        270        280        290        300
NKENEVEEVK EEGPKEMTLD EWKAIQNKDR AKVEFNIRKP NEGADGQWKK 
       310        320        330        340        350
GFVLHKSKSE EAHAEDSVMD HHFRKPANDI TSQLEINFGD LGRPGRGGRG 
       360        370        380 
GRGGRGRGGR PNRGSRTDKS SASAPDVDDP EAFPALA

Length:387

Mass (Da):42,427

Last modified:May 10, 2005 - v1

Checksum:ⁱ8C47134D22C1CCFA

GO

Experimental Info

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Non-terminal residueⁱ	1	Imported		1

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK222955 mRNA Translation: BAD96675.1 AK223138 mRNA Translation: BAD96858.1 AK312256 mRNA Translation: BAG35188.1
NCBI Reference Sequences More...RefSeqⁱ	NP_056455.3, NM_015640.3
UniGeneⁱ	Hs.530412

Genome annotation databases

GeneIDⁱ	26135

GeneIDⁱ

26135

Protein	Similar proteins		Species	Score	Length	Source
Q5VU21	SERPINE1 mRNA binding protein 1, isoform CRA_c		HUMAN		450	UniRef100_D3DQ69
SERBP1 isoform 1		PONAB		387
SERBP1 isoform 1		PANTR		387
Isoform 4 of Plasminogen activator inhibitor 1 RNA-binding protein		HUMAN		387

Protein	Similar proteins		Species	Score	Length	Source
Q5VU21	SERPINE1 mRNA binding protein 1		BOVIN		386	UniRef90_A1L5B7
SERPINE1 mRNA binding protein 1, isoform CRA_c		HUMAN		450
SERBP1 isoform 1		PONAB		387
SERBP1 isoform 1		PANTR		387
Uncharacterized protein		MYOLU		411
+84

Protein	Similar proteins		Species	Score	Length	Source
Q5VU21	SERPINE1 mRNA binding protein 1		BOVIN		386	UniRef50_A1L5B7
SERPINE1 mRNA binding protein 1, isoform CRA_c		HUMAN		450
SERBP1 isoform 1		PONAB		387
SERBP1 isoform 1		PANTR		387
Uncharacterized protein		MYOLU		411
+92

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AK222955 mRNA Translation: BAD96675.1 AK223138 mRNA Translation: BAD96858.1 AK312256 mRNA Translation: BAG35188.1
RefSeqⁱ	NP_056455.3, NM_015640.3
UniGeneⁱ	Hs.530412

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

IntActⁱ	Q5VU21, 3 interactors Q5VU21, 3 interactors

IntActⁱ

Q5VU21, 3 interactors
Q5VU21, 3 interactors

Protocols and materials databases

The DNASU plasmid repository More...DNASUⁱ	26135
Structural Biology Knowledgebase	Search...

Genome annotation databases

GeneIDⁱ	26135

GeneIDⁱ

26135

Organism-specific databases

CTDⁱ	26135
EuPathDBⁱ	HostDB:ENSG00000142864.14
PharmGKBⁱ	PA413

Phylogenomic databases

HOVERGENⁱ	HBG056357

HOVERGENⁱ

HBG056357

Miscellaneous databases

GenomeRNAiⁱ	26135

GenomeRNAiⁱ

26135

Gene expression databases

Bgeeⁱ	ENSG00000142864 Expressed in 236 organ(s), highest expression level in testis

Bgeeⁱ

ENSG00000142864 Expressed in 236 organ(s), highest expression level in testis

Family and domain databases

InterProⁱ	View protein in InterPro IPR039764 HABP4/SERBP1 IPR006861 HABP4_PAIRBP1-bd IPR032381 IHABP4_N IPR027205 SERBP1
PANTHERⁱ	PTHR12299 PTHR12299, 1 hit PTHR12299:SF29 PTHR12299:SF29, 1 hit
Pfamⁱ	View protein in Pfam PF04774 HABP4_PAI-RBP1, 1 hit PF16174 IHABP4_N, 1 hit
SMARTⁱ	View protein in SMART SM01233 HABP4_PAI-RBP1, 1 hit
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q5VU21_HUMAN
Accessionⁱ	Q5VU21Primary (citable) accession number: Q5VU21
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	May 10, 2005
	Last sequence update:	May 10, 2005
	Last modified:	November 7, 2018
	This is version 117 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)
Disclaimer	Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

UniProtKB - Q5VU21 (Q5VU21_HUMAN)

Your basket is currently empty. ⁱ

Select a section on the left to see content.

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Organism-specific databases

Subcellular locationⁱ

Cytosol

Pathology & Biotechⁱ

Organism-specific databases

Expressionⁱ

Gene expression databases

Interactionⁱ

Protein-protein interaction databases

Family & Domainsⁱ

Domains and Repeats

Phylogenomic databases

Family and domain databases

Sequenceⁱ

Experimental Info

Sequence databases

Genome annotation databases

Similar proteinsⁱ

Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

Entry informationⁱ

UniProt is an ELIXIR core data resource

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q5VU21 (Q5VU21_HUMAN)

Your basket is currently empty. i <p>When browsing through different UniProt proteins, you can use the ‘basket’ to save them, so that you can back to find or analyse them later.<p><a href='/help/basket' target='_top'>More...</a></p>

PAI-1 mRNA-binding protein variant

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Cytosol

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

Experimental Info

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

UniProt is an ELIXIR core data resource

Your basket is currently empty. ⁱ

Functionⁱ

GO - Molecular functionⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

Pathology & Biotechⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Cross-referencesⁱ

Entry informationⁱ