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UniProtKB - Q5VTZ4 (Q5VTZ4_HUMAN)
Protein
Submitted name:
Cyclic AMP-dependent transcription factor ATF-3
Gene
ATF3
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor activity Source: InterPro
- sequence-specific DNA binding Source: UniProt
GO - Biological processi
- regulation of transcription by RNA polymerase II Source: InterPro
Names & Taxonomyi
Protein namesi | Submitted name: Cyclic AMP-dependent transcription factor ATF-3Imported |
Gene namesi | Name:ATF3Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Proteomesi |
|
Organism-specific databases
HGNCi | HGNC:785, ATF3 |
VEuPathDBi | HostDB:ENSG00000162772 |
Expressioni
Gene expression databases
Bgeei | ENSG00000162772, Expressed in vena cava and 240 other tissues |
ExpressionAtlasi | Q5VTZ4, baseline and differential |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 86 – 149 | BZIPInterPro annotationAdd BLAST | 64 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 91 – 145 | Sequence analysisAdd BLAST | 55 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000156376 |
OMAi | MMVQHSG |
Family and domain databases
InterProi | View protein in InterPro IPR000837, AP-1 IPR029812, ATF3 IPR004827, bZIP |
PANTHERi | PTHR23351, PTHR23351, 1 hit PTHR23351:SF23, PTHR23351:SF23, 1 hit |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
PRINTSi | PR00042, LEUZIPPRFOS |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit PS00036, BZIP_BASIC, 1 hit |
(1+)i Sequence
Sequence statusi: Fragment.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
Q5VTZ4-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMLQHPGQVS ASEVSASAIV PCLSPPGSLV FEDFANLTPF VKEELRFAIQ
60 70 80 90 100
NKHLCHRMSS ALESVTVSDR PLGVSITKAE VAPEEDERKK RRRERNKIAA
110 120 130 140 150
AKCRNKKKEK TECLQKESEK LESVNAELKA QIEELKNEKQ HLIYMLNLHR
160 170
PTCIVRAQNG RTPEDERNLF IQQIK
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketP18847 | ATF3_HUMAN | Cyclic AMP-dependent transcription ... | ATF3 | 181 | Annotation score: | ||
A0A0A0MRJ2 | A0A0A0MRJ2_HUMAN | Cyclic AMP-dependent transcription ... | ATF3 | 153 | Annotation score: |
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Non-terminal residuei | 175 | Imported | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092803 Genomic DNA No translation available. AL590648 Genomic DNA No translation available. AL606913 Genomic DNA No translation available. |
Genome annotation databases
Ensembli | ENST00000366981; ENSP00000355948; ENSG00000162772 |
UCSCi | uc057pfw.1, human |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC092803 Genomic DNA No translation available. AL590648 Genomic DNA No translation available. AL606913 Genomic DNA No translation available. |
3D structure databases
SMRi | Q5VTZ4 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | Q5VTZ4, 1 interactor |
Proteomic databases
MaxQBi | Q5VTZ4 |
PeptideAtlasi | Q5VTZ4 |
ProteomicsDBi | 65368 |
Protocols and materials databases
Antibodypediai | 658, 572 antibodies from 36 providers |
Genome annotation databases
Ensembli | ENST00000366981; ENSP00000355948; ENSG00000162772 |
UCSCi | uc057pfw.1, human |
Organism-specific databases
HGNCi | HGNC:785, ATF3 |
OpenTargetsi | ENSG00000162772 |
VEuPathDBi | HostDB:ENSG00000162772 |
GenAtlasi | Search... |
Phylogenomic databases
GeneTreei | ENSGT00940000156376 |
OMAi | MMVQHSG |
Miscellaneous databases
ChiTaRSi | ATF3, human |
Gene expression databases
Bgeei | ENSG00000162772, Expressed in vena cava and 240 other tissues |
ExpressionAtlasi | Q5VTZ4, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR000837, AP-1 IPR029812, ATF3 IPR004827, bZIP |
PANTHERi | PTHR23351, PTHR23351, 1 hit PTHR23351:SF23, PTHR23351:SF23, 1 hit |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
PRINTSi | PR00042, LEUZIPPRFOS |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit PS00036, BZIP_BASIC, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | Q5VTZ4_HUMAN | |
Accessioni | Q5VTZ4Primary (citable) accession number: Q5VTZ4 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | December 7, 2004 |
Last sequence update: | December 7, 2004 | |
Last modified: | January 19, 2022 | |
This is version 130 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |